Immunotherapy focuses on boosting the immune system to fight cancer

What is immunotherapy and how does it work?

Immunotherapy is a type of treatment that harnesses the body's immune system to combat cancer. This video explainer from the American Cancer Society discusses various types of immunotherapies and their roles in targeting cancer cells. Still a new and quickly evoliving field, immunotherapy represents a significant advancement in cancer treatment and offers new options for patients.

A new type of immunotherapy focuses on healthy cells hijacked by tumors

Purdue University scientists are at work on a new cancer treatment that attacks immune system cells that feed and protect cancer cells rather than attacking them. The immunotherapy process promises to become a universal treatment for solid tumors. Thus far, the treatment has been tested and shown to work on human tumor cells in the laboratory and animal models.

Frequently asked questions on immunotherapy

The Cancer Research Institute takes a close look at immunotherapy and its potential for treating cancer. Immunotherapy teaches the patient's own immune system to recognize and fight cancer cells. It's especially promising as an alternative for cancers that resist chemotherapy and radiation treatment. Have all your questions about the process and its promise here.

Teaching immune cells to fight cancer

CAR T-cell therapy is a type of immunotherapy, which involves strengthening the immune system to attack cancer cells. Patient T cells, which manage immune responses and are responsible for killing pathogen-infected cells, are collected and re-engineered to produce surface-level proteins called chimeric antigen receptors. These CARs, now able to bind to specific proteins on cancer cell surfaces, are multiplied into the millions and infused back into the patient.

The difference between standard cancer treatments and emerging immunotherapies

If you've ever wondered what the difference was between immunotherapy and chemotherapy, this short video takes you through the steps. Briefly, chemotherapy attacks cancer in tumor cells directly, while immunotherapy encourages your immune system to fight it. There's more to it than that, but this delightful two-and-a-half-minute video provides a good primer.

How is immunotherapy used to fight cancer?

The Dana-Farber Cancer Institute provides a delightful Science Illustrated animation explaining PD-1/PD-L1 immunotherapy and how it fights cancer. Briefly, the treatment helps T-cells recognize cancerous cells that would ordinarily be "disguised" by proteins and attack. The fight is made more fair and effective by immunotherapy and similar cancer treatments.

The immune system is in a constant fight against mutations

At the heart of cancerous cells is the development of mutations—an ongoing and continuous process that happens frequently. So why don’t we get cancer immediately? The body’s immune system has developed intricate methods to detect and destroy cancer cells, catching the vast majority before they get the chance to evolve into tumors.

Chemotherapy slows cancer by interfering with cell division

Cancer cells divide much more frequently than most normal cells. Most chemotherapy drugs are designed to interfere with cell division, thereby targeting harmful cells while attempting to leave healthy cells alone.

What is cancer bioengineering?

While new treatments for cancer are under continuous development, researchers are increasingly using engineering principles to find wholly new strategies to combat the disease. Directions include nanoparticle drug delivery, advanced imaging tools, developing new materials to interact with cells, tissue engineering, robotic surgeries, and more. Such interdisciplinary efforts are expected to unlock new tools and therapies beyond traditional drug formulation.

How Nobel Prize-winning research unraveled why the immune system doesn't always attack itself

The 2025 Nobel Prize was awarded to scientists who discovered how immune system soldiers are typically stopped from attacking healthy tissue. The work furthered autoimmune understanding and cancer therapies.

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola

Monoclonal Antibodies mimic the antibodies produced naturally by the immune system. These molecules target specific parts of the virus, preventing them from entering cells or interfering with their ability to cause harm or infection.

Combining two cancer drugs increased the life space of mice by 30%

A study shows trametinib and rapamycin, two drugs used for cancer treatment in humans, increased mouse lifespan when used together. The medications delayed the onset of cancer and reduced chronic inflammation, results that will be explored in future research.

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

There are hundreds of subtypes of cancer, making a universal cure nearly impossible

Cancer is an umbrella term for over 200 different diseases, each with its own subtypes, genetic mutations, and behaviors. This diversity means that a treatment effective for one cancer type or patient may be ineffective for others. Moreover, as tumors grow, their cells accumulate different mutations, creating subclones with unique characteristics.

mRNA vaccines alter immune response, not DNA, to combat diseases like cancer

These vaccines—developed using techniques to create COVID vaccines—are now being tested for cancer treatment and have shown improved survival rates in patients with lung cancer. Scientists believe the research involved in developing these vaccines has opened the door to new and effective personalized cancer treatments in the future.

Tumor genetic profiling can lead to targeted treatments

Genetic profiling of tumors—based on a sample from the tumor, a patient's blood, or both—can help clinicians determine if targeted therapies known to block the growth of certain types of tumors would be appropriate for specific patients.

How does cancer actually kill someone?

While the emotional and physical tolls of cancer are often clear, the innerworkings of how cancer kills can be confusing — and terrifying to discuss. Here, oncologists explain how cancer can progress.

Immunosuppressants enable organ transplants, but come with severe side effects

This drug cocktail helps to lower your body's natural response to attack a transplanted organ. Such medications usually need to be taken for a lifetime after receiving an organ and can come with serious side effects including high blood pressure, diabetes, increased risk of some cancers, and high cholesterol, among others.

How Gleevec transformed leukemia treatment and cancer research

An outline of the discovery of imatinib (Gleevec), a ground-breaking drug that transformed the treatment of chronic myelogenous leukemia and sparked the beginning of precision medicine.

Autoimmunity is when the body attacks itself, causing inflammation

Inflammation is the body's way of healing itself, and acute inflammation saves our lives when we have injuries or infections. It increases blood flow to the affected areas to bring immune cells to fight off invaders. This often results in short-term swelling, redness, and pain.

Short-term cortisol spikes can boost the immune system

Elevated acute levels can enhance the immune system's ability to fight off infection or respond to injury. Chronic heightened cortisol levels, however, can lead to inflammation that harms cells and tissues over time.

Learn about the 'Goldilocks' of radioisotopes, which can help attack hard-to-treat cancers

Actinium-225 can be attached to a molecule that binds to cancer antigens, helping it target specific cancers in the body. It emits alpha particles that can damage DNA but do not penetrate deeply, confining the damage to nearby cancer cells. However, annual global production of actinium-225 is less than a grain of sand.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Inhalers, antihistamines, immunotherapy, and more have made allergies a multimillion-dollar market

Market research suggests that the allergies market will continue to grow in the years ahead as the number of allergy diagnoses increases, identifying new patients. Areas of growth include the increasing interest in immunotherapies designed to retrain the immune system through regular exposure to potential allergens via injections and under-the-tongue medical formulations, among other approaches.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Steve Jobs tried to treat his cancer with alternative medicine

After Steve Jobs was diagnosed with pancreatic cancer, he reportedly restricted his diet to just fruits or just fruits and vegetables, tried out hydrotherapy, and consulted psychics. There’s compelling evidence about the impact of alternative medicine on cancer patients.

The HPV vaccine reduces cervical cancer rates by 90% or more

Cervical cancer is the fourth most common cancer in women globally. Almost all cases (99%) are linked to infection with high-risk human papillomaviruses. However, cervical cancer is both treatable and preventable—and we may be able to prevent most cases through vaccination.

Autoimmune disorders are one of the top 10 killers of young and middle-aged women

Studies in the US and the UK, though conducted decades ago, have underscored that autoimmune diseases, when grouped together, are a top killer of women.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

This poison ivy knowledge quiz—accompanied by photos of the plant's varied forms—may help you identify this common rash-inducing growth.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

Iran's Revolutionary Guard Corps is independent of Iran's regular army and is one of the most powerful and influential military-political organizations in the Middle East.

Explore an interactive map of battles from the American Revolution, along with detailed summaries of each engagement

Calculate how much of your tax dollars go to each federal program based on your income, filing status, and number of children

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Hotels in Cannes, the glamorous city on the French Riviera, hire hawks to ward off seagulls during the city's famous film festival.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.