How is immunotherapy used to fight cancer?

Frequently asked questions on immunotherapy

The Cancer Research Institute takes a close look at immunotherapy and its potential for treating cancer. Immunotherapy teaches the patient's own immune system to recognize and fight cancer cells. It's especially promising as an alternative for cancers that resist chemotherapy and radiation treatment. Have all your questions about the process and its promise here.

What is immunotherapy and how does it work?

Immunotherapy is a type of treatment that harnesses the body's immune system to combat cancer. This video explainer from the American Cancer Society discusses various types of immunotherapies and their roles in targeting cancer cells. Still a new and quickly evoliving field, immunotherapy represents a significant advancement in cancer treatment and offers new options for patients.

A new type of immunotherapy focuses on healthy cells hijacked by tumors

Purdue University scientists are at work on a new cancer treatment that attacks immune system cells that feed and protect cancer cells rather than attacking them. The immunotherapy process promises to become a universal treatment for solid tumors. Thus far, the treatment has been tested and shown to work on human tumor cells in the laboratory and animal models.

The difference between standard cancer treatments and emerging immunotherapies

If you've ever wondered what the difference was between immunotherapy and chemotherapy, this short video takes you through the steps. Briefly, chemotherapy attacks cancer in tumor cells directly, while immunotherapy encourages your immune system to fight it. There's more to it than that, but this delightful two-and-a-half-minute video provides a good primer.

Immunotherapy focuses on boosting the immune system to fight cancer

The immune system detects and destroys abnormal cells, curbing the growth of many cancers. Immunotherapy works to boost the body’s immune system to target and kill cancer cells. There are many ways to accomplish this, including adaptive cell therapy, checkpoint inhibitors, vaccines, and monoclonal antibodies.

Teaching immune cells to fight cancer

CAR T-cell therapy is a type of immunotherapy, which involves strengthening the immune system to attack cancer cells. Patient T cells, which manage immune responses and are responsible for killing pathogen-infected cells, are collected and re-engineered to produce surface-level proteins called chimeric antigen receptors. These CARs, now able to bind to specific proteins on cancer cell surfaces, are multiplied into the millions and infused back into the patient.

What is cancer bioengineering?

While new treatments for cancer are under continuous development, researchers are increasingly using engineering principles to find wholly new strategies to combat the disease. Directions include nanoparticle drug delivery, advanced imaging tools, developing new materials to interact with cells, tissue engineering, robotic surgeries, and more. Such interdisciplinary efforts are expected to unlock new tools and therapies beyond traditional drug formulation.

mRNA vaccines alter immune response, not DNA, to combat diseases like cancer

These vaccines—developed using techniques to create COVID vaccines—are now being tested for cancer treatment and have shown improved survival rates in patients with lung cancer. Scientists believe the research involved in developing these vaccines has opened the door to new and effective personalized cancer treatments in the future.

How Gleevec transformed leukemia treatment and cancer research

An outline of the discovery of imatinib (Gleevec), a ground-breaking drug that transformed the treatment of chronic myelogenous leukemia and sparked the beginning of precision medicine.

Combining two cancer drugs increased the life space of mice by 30%

A study shows trametinib and rapamycin, two drugs used for cancer treatment in humans, increased mouse lifespan when used together. The medications delayed the onset of cancer and reduced chronic inflammation, results that will be explored in future research.

Lung cancer advances are making a big difference

Lung cancer deaths are declining faster than new cases due to advances in treatment. The progress illustrates what is possible, even for a cancer that has long had a poor prognosis.

The immune system fights tattoos

Our skin is a fascinating organ that wants nothing more than to protect our bodies from the outside world. Tattoos penetrate that protective wall to inject ink directly into the sensitive, immunologically rich layer of skin known as the dermis.

How does cancer actually kill someone?

While the emotional and physical tolls of cancer are often clear, the innerworkings of how cancer kills can be confusing — and terrifying to discuss. Here, oncologists explain how cancer can progress.

Physician teaches course on being a cancer patient

Stanford physician and professor Bryant Lin was diagnosed with stage four lung cancer, a terminal diagnosis. Despite its difficult implications for his life, Lin embraced the chance to teach his students from the unique perspective of a lung cancer patient. The course explored the journey from diagnosis to treatment; how to respect a patient's physical, emotional, and spiritual dimensions; and more.

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Dr. Bernard Fisher pioneered lumpectomy as a treatment for breast cancer

Dr. Bernard Fisher was a surgeon-scientist who developed and discovered cancer treatments that changed the way we treat and understand breast cancer. Despite these contributions, Fisher was also the subject of a congressional investigation that tarnished his reputation. Listen to the "Less Radical" six-episode podcast series covering the complex story of this influential doctor.

Steve Jobs tried to treat his cancer with alternative medicine

After Steve Jobs was diagnosed with pancreatic cancer, he reportedly restricted his diet to just fruits or just fruits and vegetables, tried out hydrotherapy, and consulted psychics. There’s compelling evidence about the impact of alternative medicine on cancer patients.

Photodynamic therapy is one current treatment for age-related macular degeneration

This laser-based treatment is used on advanced "wet" age-related macular degeneration patients, but it's now used less often than in the past because there are newer injection-based drugs to decrease abnormal blood vessel growth.

Calculate your risk of developing cancer

Hosted by the National Cancer Institute, this tool provides interactive charts that display the likelihood of dying from various causes—including cancer—based on factors like age, sex, race, and smoking status. By contextualizing cancer risk among other potential health threats, users can create custom charts.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

How radioactive isotopes are created and used for medical diagnostics

In particle accelerators, protons can be accelerated into other atoms to create radioactive isotopes, which can be attached to specific molecules to create radiotracers that are taken up by specific cells. Radiotracers can emit particles that produce light once they collide with an electron, and this light can be captured by a PET scanner to diagnose specific ailments.

FDA approved the first ever peanut allergy treatment in January 2020

This new medication, called Palforzia, is designed to stave off severe reactions from accidental peanut exposures with a daily dose that is increased over time under an allergist’s supervision. It’s not a treatment that should be administered during an allergic reaction, however. Epinephrine, usually administered via injection, remains the intervention for severe reactions.

Diabetes drug GLP-1 is a peptide (that's what the 'P' is for)

Glucagon-like peptide-1, or GLP-1, is one of the most well-known peptides in common use. In 2024, 26.5% of all adults with diagnosed diabetes used the substance. GLP-1 was particularly popular among people with diabetes aged 50-64, followed by younger adults and then seniors aged 65+.

A gallery of medical illustrations from NIH

The National Institutes of Health provides educational materials for broad use. The institute hosts a Flickr account with many different image galleries, including this one (with over 70 images to date) that illustrate and annotate curious phenomena, from the life cycles of a malaria parasite to the comparison of male and female bladders. Explore the gallery here.

How fighting wildfires works

Firefighters use sophisticated strategies to control wildfires that sometimes cover thousands of acres. This video breaks down how teams set up fire lines to isolate the fires by cutting down brush and trees around the existing fire, among other...

Induced pluripotent stem cells are "reprogrammed" cells

Induced pluripotent stem cells are used in a great deal of stem cell research, but many people are still unfamiliar with exactly what “iPS” cells are. This video provides a clear (and short) explanation of iPS cells for non-experts, and offers insights into why scientists are interested in these cells.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

'Buffy coats': The 1% of blood that helps fight off disease

When blood is centrifuged, white blood cells and platelets form a layer called the buffy coat between the plasma and red blood cells. This layer makes up less than 1% of blood, but its heightened leukocyte concentration makes it useful for toxicology research.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Tattoos remain visible on your skin thanks to immune cells called macrophages

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Watch this video that uses Lego bricks to explain how venture capital works.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

Explore the known asteroids, comets, and spacecraft involved in asteroid studies within our solar system with 'Eyes on Asteroids,' a 3D visualization from NASA.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

Explore an interactive map of battles from the American Revolution, along with detailed summaries of each engagement

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

Hotels in Cannes, the glamorous city on the French Riviera, hire hawks to ward off seagulls during the city's famous film festival.

Exploring the Larry Bird punch that almost changed March Madness

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

Calculate how much of your tax dollars go to each federal program based on your income, filing status, and number of children

In 1945, Surrealist artist Salvador Dalí and legendary animator Walt Disney began collaborating on a short film that was not completed until 2003, years after both men had died.