Lung cancer advances are making a big difference

A snapshot of progress in cancer treatments

The American Association for Cancer Research's "Snapshot of a Year of Progress" offers an overview of significant advancements in cancer research and treatment over the past year. Take a quick look at the rapid pace of scientific discovery and the translation of research findings into clinical practice. In 2024 alone, health regulators approved 15 new anticancer therapies alone.

Timeline of cancer research milestones

While cancer remains incurable, there's been so much progress in its treatment over the last two decades. Nature provides an abridged history of milestones and major triumphs in cancer research and treatment. Start in the year 2000, and see how much has changed in the first quarter of the new millennium

Patients are a part of the progress

Navigating a cancer diagnosis can be terrifying and overwhelming. There is a robust community of patient advocates dedicated to prevention and diagnosis, research and clinical trials, legislation, needs of individual cancer types, among others. See how patient advocacy improves cancer research leading to improved treatment options and patient care.

US cancer mortality rates have been falling for 25 years

The American Cancer Society's "Cancer Facts & Figures 2025" report provides comprehensive statistics on cancer incidence, mortality, and survival rates in the United States. Cancer rates in the US continued a long-running downward trend, driven primarily by a steep drop in lung cancers (mostly from a decrease in habitual smoking) and better preventative monitoring. This site leads to incredibly in-depth reports and slides on the current state of the fight against cancer.

Can AI revolutionize cancer detection?

Scientists have developed a tool to evaluate the risk of lung cancer, the most deadly form of the disease. Named "Sybil," this AI program was trained using CT scans with clear cancer signs, followed by scans where cancer wasn’t obvious. The tool is able to review CT scan data to predict a patient's of developing a lung cancer within six years. See how it works here.

Advanced drugs are closing in on cancer's deadliest mutations

The protein KRAS, mutated in many cancers, was deemed ‘undruggable’. Now scientists are hoping to save lives with a batch of new compounds that target it.

mRNA vaccines alter immune response, not DNA, to combat diseases like cancer

These vaccines—developed using techniques to create COVID vaccines—are now being tested for cancer treatment and have shown improved survival rates in patients with lung cancer. Scientists believe the research involved in developing these vaccines has opened the door to new and effective personalized cancer treatments in the future.

Large animals like giraffes and elephants have evolved unique cancer defenses

One may expect the larger an animal is, the more likely it is to develop cancer—simply because there are more cells and more chances for a dangerous mutation. However, some large animals show cancer rates almost 10 times lower than humans—a phenomenon known as Peto's Paradox.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Combining two cancer drugs increased the life space of mice by 30%

A study shows trametinib and rapamycin, two drugs used for cancer treatment in humans, increased mouse lifespan when used together. The medications delayed the onset of cancer and reduced chronic inflammation, results that will be explored in future research.

Physician teaches course on being a cancer patient

Stanford physician and professor Bryant Lin was diagnosed with stage four lung cancer, a terminal diagnosis. Despite its difficult implications for his life, Lin embraced the chance to teach his students from the unique perspective of a lung cancer patient. The course explored the journey from diagnosis to treatment; how to respect a patient's physical, emotional, and spiritual dimensions; and more.

Cancer is typically described by one of five stages

Stage 0 is in situ, meaning abnormal cells haven’t spread, while Stage 1 is further progressed but remains localized to the origin. Stage 2 and 3 show increasing tumor size and spread to nearby lymph nodes or tissues. Stage 4 indicates metastasis, meaning cancer has spread to distant organs.

Pneumonia was once a leading killer before penicillin treatments

In the early 20th century, pneumonia was a top cause of death worldwide, often fatal without effective treatment. Penicillin turned a once deadly infection into one of the most treatable bacterial diseases.

CAR-T is showing promise for treating lupus—previously thought to be incurable

A small number of lupus patients have remained in complete remission for years after undergoing an experimental CAR-T cell therapy that seems to eliminate enough B cells to fuel a "deep reset" of the immune system. CAR-T therapy is also being used experimentally to treat MS, myositis, and other autoimmune disorders. (Some users may experience a paywall.)

Research advances suggest death takes much longer than we realized

Recent research indicates that organs, including the brain, are better at handling a lack of oxygen after the heart stops beating than previously known. Such findings may open up possibilities that include someday reversing certain death processes and expanding the availability of organs available for organ donations. (Some users may experience a paywall.)

How is immunotherapy used to fight cancer?

The Dana-Farber Cancer Institute provides a delightful Science Illustrated animation explaining PD-1/PD-L1 immunotherapy and how it fights cancer. Briefly, the treatment helps T-cells recognize cancerous cells that would ordinarily be "disguised" by proteins and attack. The fight is made more fair and effective by immunotherapy and similar cancer treatments.

The resurgence of Black lung disease in coal miners

Black lung disease is a preventable condition long associated with coal miners who regularly breathe in toxic coal dust. Simple workplace safety procedures make the disease entirely preventable, but cases are rising. Due to lax enforcement of rules, miners in Central Appalachia are increasingly diagnosed with cases stemming from silica dust inhalation.

The disparity in life expectancy between wealthy and impoverished nations has notably narrowed

In 1950, people in Norway lived to age 72, on average, while those in Mali lived to just 26. By 2015, the countries with the worst conditions had made such significant progress that the global average life expectancy had surpassed the rate of any nation in 1950.

Turning nuclear waste into cancer medications

This video explores Terrapower, a company transforming nuclear waste into lifesaving cancer treatments. This is accomplished through the production and use of Actinium 225, a rare isotope derived from thorium, which is used in targeted alpha therapy to treat cancer.

Turning a profit with terminal illness

After Amanda Riley was diagnosed with cancer, her social media followers rallied to raise funds to ensure their favorite religious influencer could afford one miracle after another. As more than $100,000 of donations poured in, Riley shared glimpses into her health struggles, posting evidence as fake as her diagnosis. Pulling from years of journalistic investigation, this eight-episode podcast series dives into Riley's reality.

Doctors shift focus from extending lifespan to lengthening health span

As scientific advances extend the average human lifespan, many are turning their attention toward extending "health span." Health span refers to the number of years one is active and disease-free. The ultimate goal is to extend one’s health span to match one’s lifespan.

Defying the odds, Stephen Hawking outlived his ALS diagnosis by over 50 years

When diagnosed with ALS, Stephen Hawking was given two years to live. However, he survived with the progressive neurodegenerative disease for over 50 years, highlighting the disease's variability and complexity.

Addressing lifestyle factors, which influence inflammation, can cure some chronic diseases

In this video, a physician claims that he reversed a patient's Type 2 diabetes in six weeks by addressing inflammation drivers such as diet. More broadly, he argues that society needs to better consider and address numerous disease factors that are modulated by inflammation, such as stress, sleep, diet, and movement.

Learn why the Montreal Protocol may help prevent millions of cancer deaths

By restoring the ozone layer and reducing ultraviolet exposure, full implementation of the Montreal Protocol is expected to prevent about 443 million cases of skin cancer, 2.3 million skin cancer deaths, and 63 million cases of cataracts among Americans born from 1890 to 2100.

The lack of diversity in clinical trials is undermining the future of precision medicine

Medicine works better when the treatments are tailored to fit each individual person’s biology and history. Homogeneous patient selection in clinical trials means treatments and care are being refined based on only a small range of variables, some of which may not apply to you. This 40-minute podcast episode discusses the historical and current reasons for the lack of clinical trial diversity and what this means for the future of personalized medicine.

MS disproportionately sickens women, but men tend to have worse outcomes

Though the disease is more common in women, men's symptoms progress more quickly, with men more often diagnosed with progressive MS and men's cases typically resulting in more severe symptoms—perhaps due at least partly to more delayed diagnosis—and more severe disability over time.

See the evolution of Ebola vaccine and treatment development.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Scientists testing how climate change affects plants found, in a years-long simulation study, that poison ivy grew 70% faster with the resulting extra carbon dioxide.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Fish populations in the Great Barrier Reef have increased after installing waterproof speakers on the ocean floor that played recordings of sounds from healthy coral reefs.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

'Silent' fireworks have gained more interest in recent years as a quieter celebratory option.

The deadliest aspect of volcanic eruptions is often not lava, but pyroclastic flows—avalanches of ash, gas, and rock that can move more than half the speed of sound.

Venture capital is a form of funding provided to early-stage companies with high growth potential, typically in exchange for an equity (or ownership) stake

The power and influence of the American presidency have expanded significantly over time—far beyond what the founders envisioned.

Dozens of S&P 500 stocks, including Coca-Cola and Walmart—known as the dividend aristocrats—have increased dividends every year for 25 years

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives