Turning nuclear waste into cancer medications

Learn about the 'Goldilocks' of radioisotopes, which can help attack hard-to-treat cancers

Actinium-225 can be attached to a molecule that binds to cancer antigens, helping it target specific cancers in the body. It emits alpha particles that can damage DNA but do not penetrate deeply, confining the damage to nearby cancer cells. However, annual global production of actinium-225 is less than a grain of sand.

How radioactive isotopes are created and used for medical diagnostics

In particle accelerators, protons can be accelerated into other atoms to create radioactive isotopes, which can be attached to specific molecules to create radiotracers that are taken up by specific cells. Radiotracers can emit particles that produce light once they collide with an electron, and this light can be captured by a PET scanner to diagnose specific ailments.

Radioactive waste solutions include glass smelting and dumping into graphite blocks

Since radioactive materials can take seconds to millions of years to decay, their disposal or storage requires creative solutions. Besides turning liquid waste into glass or storing medical waste in lead-lined rooms, spent nuclear rods are stored in deep-water pools.

View the periodic table of radioactive elements, and a list of each's most stable isotopes

Technetium is the lightest artificial radioactive element, which is produced primarily as a byproduct of nuclear fission. Several unstable isotopes are commercially available to medical professionals and scientists, despite their radioactivity risks.

A new type of immunotherapy focuses on healthy cells hijacked by tumors

Purdue University scientists are at work on a new cancer treatment that attacks immune system cells that feed and protect cancer cells rather than attacking them. The immunotherapy process promises to become a universal treatment for solid tumors. Thus far, the treatment has been tested and shown to work on human tumor cells in the laboratory and animal models.

What is cancer bioengineering?

While new treatments for cancer are under continuous development, researchers are increasingly using engineering principles to find wholly new strategies to combat the disease. Directions include nanoparticle drug delivery, advanced imaging tools, developing new materials to interact with cells, tissue engineering, robotic surgeries, and more. Such interdisciplinary efforts are expected to unlock new tools and therapies beyond traditional drug formulation.

Particle accelerators allow physicists to create controlled nuclear experiments

Before the 1930s, scientists relied on naturally radioactive substances to learn about atomic nuclei. The first atom was split in 1932 when John Cockcroft and Ernest Walton fired a beam of accelerated protons at a lithium atom, producing alpha radiation.

mRNA vaccines alter immune response, not DNA, to combat diseases like cancer

These vaccines—developed using techniques to create COVID vaccines—are now being tested for cancer treatment and have shown improved survival rates in patients with lung cancer. Scientists believe the research involved in developing these vaccines has opened the door to new and effective personalized cancer treatments in the future.

A snapshot of progress in cancer treatments

The American Association for Cancer Research's "Snapshot of a Year of Progress" offers an overview of significant advancements in cancer research and treatment over the past year. Take a quick look at the rapid pace of scientific discovery and the translation of research findings into clinical practice. In 2024 alone, health regulators approved 15 new anticancer therapies alone.

Uranium's ability to split easily makes it the most common catalyst for nuclear power

Uranium is commonly found in rocks, water, and soil worldwide, but significant industrial processes are needed to process and enrich it for efficient reactor usage. After being irradiated in reactors, it must be cooled down before disposal.

What is CAR T-cell therapy?

A four-minute video about CAR T-cell therapy to help answer patients' questions: What is CAR T-cell therapy? How does CAR T-cell therapy work?

RTGs convert heat generated by the decay of radioactive plutonium into electricity

Radioisotope thermoelectric generators use a thermocouple—two plates of different metals joined at two junctions to make a closed circuit. When heating one junction while keeping the other cool, a voltage and an electric current are created.

The Armamentarium is a set of new gene therapy tools to fight brain diseases

Research from 29 universities and institutions across North America has resulted in the development of 1,000 tools that provide large-scale, cell-type specific targeting for the first time. These tools may be used to alter the activity of brain cells to address some neurological diseases and sleep disorders.

Antimatter engines would have the greatest energy output of all machines

These devices would annihilate matter with antimatter, converting mass into pure energy. A teacup of fuel would release energy equivalent to that of a hydrogen bomb, but stabilizing and storing that much antimatter remains a challenging task. Alternatively, hybrid systems would utilize small amounts of antimatter to initiate nuclear reactions.

Isodope is the world's first nuclear energy influencer

Isabelle Boemeke, a Brazilian fashion model and social media personality, began promoting the benefits of nuclear electricity in 2015. She now debunks common objections to it through her TikTok persona Isodope—which has more than 34,000 followers.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

The story of the Manhattan Project's unused demon core

A 3-inch, 14-pound sphere of nuclear reactive plutonium-gallium was set to be delivered to the Pacific Theater in 1945 to become the third atomic bomb dropped over Japan. When Japan surrendered, it was returned to Los Alamos in New Mexico for experiment, where two scientists would die testing whether the core could reach criticality—where it would release intense energy—via the use of a dense reflector. Watch the story here.

Protecting astronauts against space radiation

Outside the protective atmosphere of Earth, astronauts are constantly bombarded by radiation, which, among other dangers, increases the risk cancer. While those of us on Earth can mitigate the effects of similar radiation by limiting exposure,...

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

How scientists are using molecules found in acidophiles to develop new medical treatments

The Berkeley Pit, an open-pit copper mine in Butte, Montana, that ceased operations in 1982 and is now filled with highly acidic water, is home to various species of fungi and yeast. These extremophiles produce unique compounds that may have anti-inflammatory benefits and have already been used to create an antibiotic for staph infections.

Biotech is trying to boost drug production efficiency—using chicken eggs

A company called Neion Bio is genetically engineering birds in a bid to produce medical compounds, a herculean task that scientists have struggled with for decades. The US FDA has approved only one chicken-derived drug in the past—an expensive treatment for a rare liver disorder. (Some users may encounter a paywall.)

Physician teaches course on being a cancer patient

Stanford physician and professor Bryant Lin was diagnosed with stage four lung cancer, a terminal diagnosis. Despite its difficult implications for his life, Lin embraced the chance to teach his students from the unique perspective of a lung cancer patient. The course explored the journey from diagnosis to treatment; how to respect a patient's physical, emotional, and spiritual dimensions; and more.

The North American waste management market was worth $208B in 2019

Burning waste to generate energy is a $10B industry in the US alone. A growing number of major companies—including Amazon, Subaru, and American Airlines—are pursuing "zero landfill" sustainability goals.

How does cancer spread through the body?

Cancer usually begins with one tumor, but it can spread to other organs if not removed. This video breaks down how cancer moves to these new areas and why some organs are more likely to get infected than others.

See how to make a baby with 3 parents, a process called mitochondrial replacement therapy

This primer video dives into the science of mitochondrial disease risks, how this controversial mitochondrial replacement technique can work, and why proponents say this reproductive advance—already legalized in the UK and Australia—is needed in the United States.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Turning a profit with terminal illness

After Amanda Riley was diagnosed with cancer, her social media followers rallied to raise funds to ensure their favorite religious influencer could afford one miracle after another. As more than $100,000 of donations poured in, Riley shared glimpses into her health struggles, posting evidence as fake as her diagnosis. Pulling from years of journalistic investigation, this eight-episode podcast series dives into Riley's reality.

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Watch how deep-sea mining equipment collects and processes polymetallic nodules—metal-rich, potato-shaped rocks—from the ocean floor and creates environmentally damaging plumes of sediments.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

Sony set the standard for cylinder-shaped batteries when it repurposed manufacturing equipment used to make rolls of magnetic recording tape.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

Planeterrellas create artificial auroras that mimic the atmospheric displays of light by setting up an electric field between two metal balls in a jar filled with a small amount of air.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

Watch this video that uses Lego bricks to explain how venture capital works.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.