Learn about the 'Goldilocks' of radioisotopes, which can help attack hard-to-treat cancers

Astatine-211 is a radioisotope that can be used for therapeutic cancer treatment

With less than 30 grams in the Earth's crust at any given time, astatine is the rarest naturally occurring element. Its decay produces alpha particles that can damage diseased cells with the same impact as 10,000 electrons.

Turning nuclear waste into cancer medications

This video explores Terrapower, a company transforming nuclear waste into lifesaving cancer treatments. This is accomplished through the production and use of Actinium 225, a rare isotope derived from thorium, which is used in targeted alpha therapy to treat cancer.

How radioactive isotopes are created and used for medical diagnostics

In particle accelerators, protons can be accelerated into other atoms to create radioactive isotopes, which can be attached to specific molecules to create radiotracers that are taken up by specific cells. Radiotracers can emit particles that produce light once they collide with an electron, and this light can be captured by a PET scanner to diagnose specific ailments.

Particle beams can be used to alter the surface properties of artificial joints

Surface hardening and embedding specific elements or coatings can improve the biocompatibility and bone tissue integration of these implants. Particle accelerators are significant sources of the radioisotopes needed in medical diagnostics, and microwave linear accelerators are used in the majority of cancer irradiation treatments.

View summaries of the most common types of radioactive decay and their associated particles

The alpha particle has the strongest ability to ionize other atoms it strikes, but it also does not travel very far before colliding with something and being absorbed. Gamma particles—high-energy photons—do not interact with matter as easily and therefore possess the greatest penetrating power, though this also makes their ionizing potential the smallest.

View the periodic table of radioactive elements, and a list of each's most stable isotopes

Technetium is the lightest artificial radioactive element, which is produced primarily as a byproduct of nuclear fission. Several unstable isotopes are commercially available to medical professionals and scientists, despite their radioactivity risks.

A list of five everyday products that rely on radioactivity, including exit signs and gemstones

Like some glow-in-the-dark wristwatches, some exit signs contain sealed tubes of tritium—radioactive hydrogen gas—which emit low-energy beta particles that react with surrounding elements to produce light, making them visible without batteries. In smoke detectors, smoke particles disrupt the steady flow of ions generated by americium-241.

Scientists turn alchemists, transforming transform lead into gold

Fulfilling alchemists' dreams, scientists at the Large Hadron Collider (LHC) transmute lead into gold. While the 86 billion gold nuclei produced were short-lived, the experiment sheds light on how electromagnetic fields can play a critical role in nuclear transmutation.

Cyclotrons move particles in spiral paths of increasing radius

After particles are injected into the center of the device, an alternating electric field and a constant magnetic field energize the particles as they spiral outward toward a target. Cyclotrons are common in hospitals that perform molecular imaging, which relies on radioactive components that decay within hours.

Gamma Knife surgery uses incredibly precise, high-energy light to treat patients

A form of brain stereotactic radiosurgery, this non-invasive technology concentrates beams of light onto specific tumors to damage the DNA of malignant cells, killing them. The gamma rays used are in the same part of the electromagnetic spectrum as those produced in nuclear reactions, cosmic ray collisions, and radioactive decay.

Advanced drugs are closing in on cancer's deadliest mutations

The protein KRAS, mutated in many cancers, was deemed ‘undruggable’. Now scientists are hoping to save lives with a batch of new compounds that target it.

Teaching immune cells to fight cancer

CAR T-cell therapy is a type of immunotherapy, which involves strengthening the immune system to attack cancer cells. Patient T cells, which manage immune responses and are responsible for killing pathogen-infected cells, are collected and re-engineered to produce surface-level proteins called chimeric antigen receptors. These CARs, now able to bind to specific proteins on cancer cell surfaces, are multiplied into the millions and infused back into the patient.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Where radon comes from and why it may be the most dangerous source of radioactivity

Released from underground bedrock before passing through soil, this radioactive gas is produced from the decay of uranium, thorium, and radium and accounts for about half of all human exposure to radiation. It is the leading cause of lung cancer among nonsmokers and can build up in enclosed spaces such as buildings without proper ventilation to dilute the gas.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Why taking potassium iodide to protect against radioactivity is unlikely to be effective

Since the thyroid gland cannot distinguish between radioactive and non-radioactive iodine, taking potassium iodide pills causes the thyroid to absorb the medication, leaving it unable to take up radioactive iodine from the environment. However, while this protects the sensitive gland against the most prominent radioisotope produced in nuclear accidents, it does not protect other body parts or shield against other radioactive substances.

Exposure to ionizing radiation from nuclear accidents can damage DNA

The damage can increase the risks of cancer, cataracts, heart disease, and other illnesses based on exposure times and intensities. Contaminated food, water, air, or soil from near nuclear accidents can further prolong one's exposure.

Tumor genetic profiling can lead to targeted treatments

Genetic profiling of tumors—based on a sample from the tumor, a patient's blood, or both—can help clinicians determine if targeted therapies known to block the growth of certain types of tumors would be appropriate for specific patients.

This scientist treated her own cancer

Virologist Beata Halassy treated her own breast cancer by injecting the tumor with lab-grown viruses. Though this self-treatment worked, it has not been approved for widespread use. Read to learn more about her fascinating experience, and how it has led to conversations about safety and ethics.

The Armamentarium is a set of new gene therapy tools to fight brain diseases

Research from 29 universities and institutions across North America has resulted in the development of 1,000 tools that provide large-scale, cell-type specific targeting for the first time. These tools may be used to alter the activity of brain cells to address some neurological diseases and sleep disorders.

Experiments suggest nuking a metal-rich asteroid may strengthen it

Scientists exposed meteorite samples to proton irradiation at CERN to mimic the effects of a nuclear detonation. The material exhibited greater resistance to breaking after the exposure, suggesting nuclear weapons may better serve to deflect asteroids, not break them.

How radio works

Antennae tune a radio to a particular frequency (determined by the listener on their radio's dial) while tuning out all the other stations being broadcast. AM, short for amplitude modulation, and FM, short for frequency modulation, decode audio signals differently, leading to differences in sound quality and the distance a station can travel.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

Fertility treatments linked to increased risk of cancer among offspring

Recent research has explored potential links between increased childhood cancer occurrence, particularly leukemia, and assisted reproductive technology (ART). Though some studies have detected this type of association, researchers caution that it remains unclear if ART itself, fertility drugs, underlying infertility of the parents, or other unknown factors may explain any increased cancer numbers among ART-conceived children. Overall, the incidence of cancer in children, regardless of conception method, is very low.

Marie Curie pioneered radioactivity research, for which she won two Nobel Prizes

Marie Curie and her husband isolated polonium and radium despite poor lab conditions and financial hardship. President Harding, on behalf of the women of America, presented her with one gram of radium in 1921 in recognition of her service to science.

How Nobel Prize-winning research unraveled why the immune system doesn't always attack itself

The 2025 Nobel Prize was awarded to scientists who discovered how immune system soldiers are typically stopped from attacking healthy tissue. The work furthered autoimmune understanding and cancer therapies.

Alpha-gal allergy is a problem for red meat lovers, and that same sugar is an issue for xenotransplants, too

In recent years, researchers have discovered ticks can induce spontaneous meat allergies in people they bite, a particularly problematic condition for previous meat lovers. This 18-minute podcast from RadioLab breaks down the cause.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Watch how deep-sea mining equipment collects and processes polymetallic nodules—metal-rich, potato-shaped rocks—from the ocean floor and creates environmentally damaging plumes of sediments.

When caught in the mouths of cardinal fish, seed shrimp release glowing, bioluminescent chemicals, which alert predators of the cardinal fish, prompting the shrimp's ejection.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

This poison ivy knowledge quiz—accompanied by photos of the plant's varied forms—may help you identify this common rash-inducing growth.

Sony set the standard for cylinder-shaped batteries when it repurposed manufacturing equipment used to make rolls of magnetic recording tape.

The first image of a black hole was captured by creating an Earth-sized virtual observatory from a network of eight radio telescopes.

Hotels in Cannes, the glamorous city on the French Riviera, hire hawks to ward off seagulls during the city's famous film festival.

While the first exchange-traded fund (a 'basket' of different assets that can be bought and sold on a stock exchange) in the US only launched in 1993, the global ETF market has grown to more than $10T in the short time since.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Brian Wilson wrote the Beach Boys' 'Don't Worry Baby' for the Ronettes, but the legendary girl group rejected it.