Alpha-gal allergy is a problem for red meat lovers, and that same sugar is an issue for xenotransplants, too

Tick bites can fuel an allergy to a sugar molecule in red meat

Alpha-gal syndrome is on the rise globally as ticks spread due to climate shifts. Bites from some ticks can trigger a sensitivity to a sugar molecule called alpha-gal found in mammal meat, which can lead to allergic responses to hamburgers and steak, among other products. Listen to an expert’s tips for avoiding this allergy, including quickly removing any ticks to limit exposure to their saliva or vomit.

The science of food allergies

Why do certain substances trigger an immune response while others don't? Listen to researchers explain the science in this five-minute video. Food allergies affect around 8% of children and 2% of adults in the US, and—unlike sensitivity or intolerance—they involve the immune system mistaking certain harmless proteins in foods as dangerous invaders, triggering a rapid and sometimes severe defense response.

The word allergy is partly derived from the Greek word 'allos' for 'other'

For people with allergies, their immune systems recognize substances as a harmful "other"—cuing an inflammatory response. This podcast explores allergy details and related topics, including how scientists are interested in if the same allergic response mechanisms could underpin other health issues, including severe, painful symptoms around the time of menstrual cycles. Since estrogen acts on white blood cells called mast cells, which leads to the release of histamines—similar to what happens during allergic responses—an understudied question is whether the same process is fueling some of the uncomfortable symptoms around menstruation. An allergist guest notes this raises questions about if antihistamine medications like Pepsid might alleviate them, something that hasn't yet been explored in clinical trials.

Neural replays in mice help explain food aversions

Princeton University scientists published research in 2025 analyzing how mice learn to associate certain foods or flavors with feeling ill—even when there’s a time gap between eating something and feeling sick. The work, performed with grape Kool-Aid and injections of a substance that made mice sick, traced the literal “gut reaction” of how gut distress signals are linked to neural replays of what the mouse ate.

Pig-to-human transplants have raised concerns about pig living conditions

Pigs are the current first choice for xenotransplantation procedures, yet such work gives some researchers and animal welfare advocates pause. Concerns include that pigs would have a poor quality of life since the animals must live in a strictly-controlled, hyper-clean environment to avoid risky pathogens.

Most penicillin allergy diagnoses are wrong

A Freakonomics Radio episode investigates why so many people mistakenly believe they’re allergic to penicillin. This widespread misdiagnosis leads to costlier, less effective treatments and contributes to the growing problem of antibiotic resistance.

Zoo animals have developed allergies, too

Although scientists do not know if allergies manifest among wild animals—and if animals can survive with them—in a zoo setting, veterinarians have observed zoo animals with common allergy symptoms, including itchiness, crusty skin, and runny eyes. Veterinarians have identified Asian elephants with pollen allergies and at least one jaguar with an allergy to fleas.

How spoiled meat helped uncover a bacterium that can survive the vacuum of space

When a can of ground beef and pork spoiled despite attempts to sterilize it with gamma radiation, researcher Arthur Anderson isolated the bacteria in the food and discovered Deinococcus radiodurans. The polyextremophile has since been found on the walls of nuclear reactors and overcomes radiation damage through highly optimized DNA repair mechanisms.

Why processed foods can be so addictive

In recent years, many critics have voiced their concerns about the food industry and how ultra-processed foods affect our health. Despite our awareness of these issues, processed foods are still incredibly hard to remove from our diet. In this podcast by The Guardian, Dr. Chris van Tulleken explains how “junk food” is created to get us hooked, how it negatively affects us, and what we can do to improve our eating habits.

People can—and have—contracted leprosy from armadillos

A 2011 study linked multiple human cases to the handling of armadillos or the consumption of their meat. The research couldn't document direct transmission, but did find that the animals and humans shared the same exact strain of the disease.

Find dozens of allergen-free recipes

This collection of allergen-free meal and snack recipes, designed by celebrity chefs and others, was curated by the nonprofit Food and Allergy Research & Education group. It includes items like taquitos, pizza, chickpea burgers, various desserts, and more.

Genetic engineering mice is one idea to reduce Lyme disease transmission

Wild white-footed mice are the main carriers of Lyme. A research team is hoping to genetically engineer mice, using CRISPR, to make the animals immune to Lyme. They're proposing a field trial where they would insert a gene with an antibody to Lyme infection to break the disease transmission cycle on a private island and then try it in Nantucket if that goes well. Simply killing the mice isn't an option because it would upend food webs. Unlike traditional vaccines, this "heritable immunization" would pass from one generation of mice to the next.

How a deadly antarctic expedition turned poisonous

A deadly 1912 scientific expedition to the Antarctic took a turn for the worse when the expedition team's leader turned to man's best friend to fuel their journey. This 21-minute podcast episode provides a glimpse into the real-life dangers of...

The gut microbiome may play a major role in autoimmune disease and symptom flare-ups

Certain unhealthy foods can promote gut bacterial growth and inflammation in the lining of the gut, potentially disrupting its lining—leading to a leaky gut that may allow pathogens to dribble out into the bloodstream, fueling further inflammation that can both cause disease flare-ups and set the stage for future disease development.

Natural toxins produced on plants or consumed by animals may cause food poisoning

When humans eat plants with certain natural toxins on them—including a family of toxins called aflatoxins that fungi produce on crops like peanuts and corn— they can become ill with food poisoning. Toxins can still harm humans even if animals or plants appear fine to the human eye. The World Health Organization advises that we should throw away moldy or discolored foods, refrain from eating wild plants or mushrooms that aren’t definitively nonpoisonous, and remember that just because something is “natural” it’s not always safe to eat.

Lactose intolerance is not the same as a dairy allergy

Lactose intolerance can develop in adulthood and can be influenced by genetic factors, culture, and dietary practices. Times of famine may have favored those who could digest dairy, naturally selecting them more, resulting in lactase persistence.

The science of dogs, from wolf origins to color-blindness

This under 10-minute podcast episode dives into the rich, fascinating science behind dogs: From their world-class sense of smell to their domestication from wolves.

Poison ivy is in the same family as mangoes, cashews, and pistachios—and they all produce oily urushiol in their raw, unprocessed state—but they are typically prepared in ways to avoid causing human discomfort.

Two festival-goers were hospitalized after receiving peptide injections, raising questions

Investigative journalism shop ProPublica wrote about two people who became extremely ill following antiaging peptide injections. Authorities were examining whether the individuals were sickened by an infection, contamination related to the injections, or an issue with the medication itself, according to documents obtained by the journalists at ProPublica.

Health food broke into the mainstream by the 1980s

A 1984 New York Times story noted that Americans were eating less red meat than a decade prior, and that, in general, the country was “talking, thinking and worrying about what they eat to a degree unique in the nation's history.” The feature then details foods that were then considered bizarre: whole-grain muffins, hummus, and a variety of vegetarian dishes. (Some readers may experience a paywall.)

Risks of GLP-1s include health side effects, counterfeit drugs, and more

This episode interviews researchers and patients who have used semaglutide to explore some of the potential risks associated with using the drug to lose weight. These include insurance challenges, health scares related to counterfeit versions of these drugs, and some users lose their ability to enjoy food.

The basics of synthetic meat

Lab-grown meat companies promise to remove animal slaughter from the production process. But they have run into a few road bumps along the way.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Cold-blooded reptiles seek heat, and that behavior may help combat fungal infections

This Radiolab podcast episode takes on the idea that though our human bodies are too warm for the majority of fungal species to effectively replicate inside our bodies, that's not the case for reptiles. Yet when those species warm their bodies by basking in the sun on rocks, they can soak up heat and may also help keep fungal infections in check.

Genetic tests aren't always actionable, which is one reason genetic counselors are so vital

This podcast interview with a Harvard Medical School professor focused on cancer genetics and prevention discusses the specifics of genetic testing and insights and the challenges of processing the outcomes of the testing and what may be actionable—or not.

Tattoo inks are largely unregulated by the FDA

With hundreds of ink manufacturers, all unregulated by the FDA, it’s hard to determine the exact ingredients in tattoo inks. Some pigments may contain carcinogenic chemicals, such as heavy metals and aromatic hydrocarbons, or even bacterial contaminants. Red ink often causes allergic reactions and may even contain lead or mercury.

Multiple sugar substitutes were accidental discoveries when lab workers didn't wash their hands

Saccharin, aspartame, and cyclamate all have origin stories from lab workers tasting something sweet on their hands. A Johns Hopkins University worker in the late 1800s, for example, tasted something sweet on his (unwashed or poorly washed) hands during dinner, prompting him to then taste everything on his lab bench in order to identify that the sweetness was a compound derived from his overheated coal tar—a substance he later named saccharin. (Some users may encounter a paywall.)

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Animal phobias are likely the most common type of phobias, followed by an extreme fear of heights.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

Tattoos remain visible on your skin thanks to immune cells called macrophages

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

Up to a million Girl Scouts sell about 200 million cookie boxes every spring, generating $800 million, largely because refusing a child is frowned upon

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

When you complete a CAPTCHA on a website to prove you are human, you may be unknowingly training algorithms for self-driving cars, whose systems require training data to help identify crosswalks, bicycles, and other outdoor objects.