How scientists are using molecules found in acidophiles to develop new medical treatments

Why bacterial bioremediation may help counter the negative effects of past chemical solutions

Molecules such as DDT, a synthetic insecticide, and PFAS—"forever" chemicals used to make products resistant to heat, water, and grease—have historically been used across various industries but are now known to be harmful. Microbes that can convert some of these substances into nontoxic products, such as water and carbon dioxide, have already been identified, with ongoing research to find others.

The adaptations of metallophiles and how they can be harnessed for bioremediation

These extremophiles have adapted to biomes with very high concentrations of metals and toxic chemicals by developing mechanisms to isolate these substances within cellular compartments and break them down into less harmful forms with specialized proteins. They have the potential to support the decontamination of metal-rich wastewater and soil, as well as the extraction of rare-earth metals.

Read a technical review of extremophile categories, including the habitats of each

Acidophiles can survive in environments with acidity greater than that of the human stomach, and some radiophiles can live in places with radiation exposure hundreds of times higher than what is lethal to humans. Piezophiles—formerly known as barophiles—have been found in the Mariana Trench, where pressures are over 1,000 times larger than those on Earth's surface.

View the industrial applications of extremozymes, from food safety to antibiotic production

Extremophiles possess unique enzymes and organic molecules that have enabled them to adapt to and thrive in otherwise lethal environments. Because these conditions resemble those found in various areas of manufacturing and production plants, these organisms and their macromolecules can optimize industrial processes where conventional catalysts would lose their ability to speed up reactions.

A visualization of mycoremediation, where fungi extract toxic and radioactive pollutants from soil

As organisms such as mushrooms grow, they develop large networks of root-like structures called mycelium that spread underground and release enzymes that break down contaminants. By absorbing these chemicals, fungi limit the damage caused by these toxins and localize them within the organism for easier collection and disposal.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

The discovery of the first extremophile and how it revolutionized DNA analysis

While investigating samples taken from within and around the hot springs at Yellowstone National Park, microbiologist Thomas Brock discovered Thermus aquaticus, a microorganism that thrived in hot water. It contained an enzyme called Taq polymerase, a critical molecule in polymerase chain reaction—a molecular photocopier that amplifies genetic signals to improve medical diagnostics.

Oxford scientists turned Fleming’s mold discovery into medicine

In 1939, a team at Oxford—including Howard Florey, Ernst Chain, and Norman Heatley—revived Fleming’s forgotten discovery. Using makeshift equipment like bedpans and milk churns, they purified enough penicillin to prove it could treat deadly infections.

How a polluted New York City waterway created extremophiles hungry for 'black mayonnaise'

In the 19th century, coal processing plants, oil refineries, a tannery, and other industries lining the Gowanus Canal contaminated its waters with coal tar, sewage, and other pollutants, forming the toxic sludge. Samples taken from the site before clean-up efforts revealed over 450 species of microbes with metabolisms adapted to break down these contaminants.

Bacteria have been genetically engineered to bioluminesce when wine has spoiled

Developed by researchers at Hebrew University, the method involves the firefly enzyme luciferase, which emits light from within bacteria expressing when they are in the presence of acetic acid vapors produced by wine. The process provides affordable, on-site, real-time monitoring of fermentation quality.

Microbes are essential to creating the many varieties of cheese, influencing texture and taste

Microbes break down proteins and fats and produce compounds with distinct tastes. These microbes can include bacteria (like the one used to give Swiss its trademark holes), molds (like the ones that give blue cheese its distinctive veining), and countless other tiny organisms.

How the environmental diversity of coral reefs provides potential medical treatments for humans

As immobile animals, corals and the organisms that live on them have evolved a suite of chemical compounds to prevent disease and ward off predators they cannot outrun. These include antibiotics, antivirals, and powerful toxins that target the nervous system and are studied for applications involving pain management and neurological treatments.

Weird ways critical minerals are being mined

Critical minerals like lithium, cobalt, and graphite are economically crucial non-fuel resources subject to supply chain risks. To diversify production, scientists developed odd ways to harvest them. This article breaks down the weirdest approaches, including extracting minerals from seawater using algae, phytomining plants, and asteroids.

A look at anoxygenic photosynthetic bacteria, which do not produce oxygen

Rather than using water to produce organic compounds and release oxygen, purple and green sulfur bacteria take up hydrogen sulfide, carbon dioxide, and light to produce water, elemental sulfur, and a carbohydrate. Other organisms can take up various molecules and elements, such as iron, which can replenish the electrons in pigments involved in light-dependent reactions.

A look at the Kidd Creek Mine in Canada, which houses the world's oldest isolated water

The mine sits on the Precambrian Canadian Shield—an ocean floor dating back 2.7 billion years. Exhibiting a musty smell, the water is 10 times saltier than seawater and offers insights into Earth's ancient seabed.

Why are archaeologists brewing ancient beers?

Archaeologists have managed to brew beer from yeast found inside jugs abandoned thousands of years ago. This article explores why scientists are recreating these ancient beverages and what they hope to learn. People have been drinking beer for...

The ‘humongous fungus’ may be the largest organism on Earth at more than 2,300 acres

Discovered in 1988, when it was only covering 400 acres, this massive colony of Armillaria ostoyae, based in Oregon, has taken hold among the tree roots of the Malheur National Forest. It consists of a vast network of unique long black filaments of fungal tissue called rhizomorphs that grow under the soil and infect tree roots, nourishing the fungus but killing the trees. Researchers believe this fungal growth dates back more than 8,000 years and currently weighs approximately 35,000 tons.

LSD (better known as acid) was created in 1938 by Swiss chemist Dr. Albert Hofmann

Lysergic acid diethylamide, better known as LSD or acid, was first developed synthetically in 1938 by Swiss chemist Dr. Albert Hofmann. It's since become a linchpin for an entire aesthetic, fueled a counterculture movement, and is being studied for potential therapeutic uses.

Leprosy bacteria are sometimes grown on mouse feet for research

The main leprosy-causing bacterium can't be grown in a petri dish, so the disease is challenging to study in the lab. For research purposes, it has been grown in the foot pads of mice.

What's next for gut microbiome science?

A Stanford microbiologist explores what we don't yet know about the gut microbiome—such as whether we can engineer the bacterial species within it—and the current scientific advances in the field.

Most fungal pathogens can't survive the heat of our bodies

Fungal pathogens typically struggle to survive human body temperatures, but researchers hypothesize that global warming conditions will force fungi to adapt to hotter temperatures, with implications for their ability to also survive within our bodies. That type of evolutionary adaptation would lead to more dire health threats for humans.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Watch how deep-sea mining equipment collects and processes polymetallic nodules—metal-rich, potato-shaped rocks—from the ocean floor and creates environmentally damaging plumes of sediments.

Read a deep dive on the 'all-purpose healing' peptide BPC-157

The unapproved peptide—which has received glowing testimonials from bodybuilders, biohackers, popular podcasters, and some in the MAHA movement— is often sourced from China. It has been used for myriad conditions. But scientific questions about the substance abound, including whether it's truly a natural substance produced by the human body, since genetic material that codes for its unique amino acid sequence hasn't been found in the human genome or the gut microbiome. Other unknowns include how it works in the body, which receptors it targets, and its safety, since evidence beyond anecdotes remains scant in humans.

Find fracking wells where you live and what chemicals operators are using

Fracturing fluid recipes are largely proprietary, but FracFocus has maintained a database of chemical disclosures since 2011. Today, the Department of Energy-affiliated nonprofit has more than 240,000 disclosures, along with a searchable database of fracking wells by state, county, and city.

A four-billion-year-old meteorite reignited the debate about life on Mars

Recovered from Antarctica in 1984, ALH84001 contained organic compounds, magnetite and iron sulfide grains of potential biological origin, and features that resembled fossilized bacteria. With technological advancements, scientists found abiotic origins for these features in the following decades.

In 2009, accidentally drilling into magma provided time capsules of volcanic glass

While drilling for geothermal energy in Iceland's Krafla Geothermal Field, magma encountered at a depth of 2,100 meters quickly formed glass upon making contact with drilling fluid. By trapping dissolved gases, volatile chemicals, and the physical characteristics of magma before cooling, the glass acts as a time capsule of ancient volcanic activity and magmatic conditions.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

How fecal transplants work

1,700 years ago, Chinese alchemist Ge Hong was renowned for his soup that could cure diarrhea-stricken patients. It had a surprising secret ingredient: feces. While it might seem unwise to consume feces, exciting new research suggests that taking...

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.

Scientists have struggled to pin down Ebola's natural reservoir species for decades, but the available evidence suggests that it's very likely fruit and insect-eating bats found in Africa.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

Poison ivy was sent to Europe in the 1600s as an exotic, ornamental oddity, where it was purposefully grown in the English royal gardens at Kew, the Faculty of Medicine in Paris, and a few other locations.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

See how fireworks are made and learn how metals like magnesium and copper are responsible for different colors.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.