View the industrial applications of extremozymes, from food safety to antibiotic production

An overview of extremophiles and the biochemical adaptations employed by various types

These organisms thrive in environments that would normally be inhospitable to most living things by using molecules that help counter deadly environmental factors. These include antifreeze-like proteins that prevent psychrophiles from freezing and rupturing in polar regions, and osmoprotectants that prevent some extremophiles from losing water to salty environments.

Why extremophiles may play an important role in terraforming Mars

Possessing unique biochemicals that can detoxify extreme environments and resilience against the Martian surface that is lethal to humans, scientists are exploring whether colonies of these organisms can transform small areas of the Red Planet into future habitats for humans. Extremophiles may also be best equipped to serve as microscopic factories for the fabrication of essential polymers.

The adaptations of metallophiles and how they can be harnessed for bioremediation

These extremophiles have adapted to biomes with very high concentrations of metals and toxic chemicals by developing mechanisms to isolate these substances within cellular compartments and break them down into less harmful forms with specialized proteins. They have the potential to support the decontamination of metal-rich wastewater and soil, as well as the extraction of rare-earth metals.

Breaking down the challenges of alkaline environments and how extremophiles survive them

These areas are far less acidic than the interiors of most organisms' cells, and this imbalance draws protons that are needed for various metabolic processes, including energy production, out of cells. To counter these effects, some alkaliphiles have developed stronger proton regulation across their cellular membranes and proteins that drive these processes with greater stability amid such acidity imbalances.

The discovery of the first extremophile and how it revolutionized DNA analysis

While investigating samples taken from within and around the hot springs at Yellowstone National Park, microbiologist Thomas Brock discovered Thermus aquaticus, a microorganism that thrived in hot water. It contained an enzyme called Taq polymerase, a critical molecule in polymerase chain reaction—a molecular photocopier that amplifies genetic signals to improve medical diagnostics.

Learn how environmental conditions are optimized to increase bioremediation efficacy

Through biostimulation, Indigenous microbes are provided with moisture, nutrients, or oxygen to prevent their death and ensure optimal progression of their biochemical reactions. Bioaugmentation can introduce new microbial cultures to target specific compounds not natively found in the environment, while landfarming can spread or aerate contaminated soil to improve access to contaminants.

How scientists are using molecules found in acidophiles to develop new medical treatments

The Berkeley Pit, an open-pit copper mine in Butte, Montana, that ceased operations in 1982 and is now filled with highly acidic water, is home to various species of fungi and yeast. These extremophiles produce unique compounds that may have anti-inflammatory benefits and have already been used to create an antibiotic for staph infections.

Making industrial chemicals with synthetic biology

A new report forecasts that synthetic biology will transform from creating niche, environmentally friendly products to creating new molecules within the next decade.

Recombinant DNA technology turns microorganisms into protein factories

Genes for molecules such as insulin can be inserted into loops of bacterial DNA called plasmids and reinserted into bacteria. Once placed in fermentation tanks, these bacteria use the gene to produce these molecules, which are then harvested and purified for eventual use.

How a polluted New York City waterway created extremophiles hungry for 'black mayonnaise'

In the 19th century, coal processing plants, oil refineries, a tannery, and other industries lining the Gowanus Canal contaminated its waters with coal tar, sewage, and other pollutants, forming the toxic sludge. Samples taken from the site before clean-up efforts revealed over 450 species of microbes with metabolisms adapted to break down these contaminants.

Scientists from the frontline discuss the future of antibiotics and superbugs

Superbugs are a very real problem, but researchers around the world are working to advance our understanding of these pathogens and develop new medicines. This podcast talks with several scientists on the frontier of superbug research, offering insight into what we know—and what the future of medicine may look like.

Bioluminescent reaction enzymes are often used in biomedical research

Near-infrared luciferase systems allow researchers to image and analyze cellular activity in living animals because they penetrate tissue more deeply than visible light. This provides a means of studying gene expression and protein interactions without harming the animals.

Long-term evolution experiments use microbe's short generations to speed up selection

With quick generations of microbes, scientists can speed up the evolutionary process, with projects like the LTEE in California running for 40 years and generating 80,000 generations of E. coli.

The 'Penicillin Girls' made mass production possible

In Oxford during the early 1940s, six female technicians—later dubbed the “Penicillin Girls”—worked long hours tending mold cultures and extracting tiny amounts of penicillin.

Even in recent history, adaptations to the environment drove human evolution

Through genetics, environmental pressures, and cultural influences, humans have evolved to tolerate lactose, develop varying skin pigmentation, and acquire genetic resistance to diseases like bubonic plague. The metabolic and digestive systems of Indigenous peoples have adapted to their diet, which is influenced by the availability of food and water.

Radioactive elements can generate electricity, sterilize products, and date artifacts

Since their discovery in the 1890s, these substances have been incorporated throughout our daily lives, from treating food packaging and improving microbial safety to their presence in smoke detectors and gauges for ice cream aeration.

The history of molecular gastronomy, from thickening yolks with alcohol to making art with food

Before understanding why they worked, humans used scientific principles, including designing solutions and analyzing outcomes, to develop preservation methods like curing meat and fermenting vegetables. By the 20th century, the application of industrialized food preparation to smaller kitchens set the stage for the subdiscipline of food science.

The era of advanced farming machines

Traditional agriculture, which for millennia was conducted primarily as subsistence farming by millions of workers, has been transformed since the industrial revolution. Agribusinesses continue to develop newer, more specific tools to streamline the...

EXTREMA is a smart city system protecting residents from heat-related health risks

The mobile application is designed to protect citizens in select European cities from extreme temperatures by calculating the heat index at a specific location and providing personalized information to users. Municipal governments can also utilize it to inform emergency responses, such as determining when and where to open cooling centers.

Explore the water footprint of producing various proteins, fruits, and vegetables

This interactive gallery highlights the various types of water behind the production of biofuels, foods, and materials such as cotton. Diets high in bovine meat, whose production requires 15,415 liters of water per kilogram (1,847 gallons per pound), are among the most water-intensive, whereas every kilogram of vegetables uses 322 liters of water (39 gal/lb) to produce.

Why the abundance of RuBisCO in photosynthetic cells may come from its inefficiency

Despite pulling about 115 billion tons of carbon dioxide from the atmosphere to build organic molecules each year, the enzyme instead binds oxygen at least one in five times, needlessly costing cells energy. To compensate for this and its processing of no more than 10 molecules per second—versus thousands processed by a typical enzyme—it's become the most abundant enzyme on Earth.

A first-of-its-kind clinical trial taps livers from gene-edited pigs to clean blood

The experimental dialysis-like treatment from United Therapeutics, eGenesis, and OrganOx, is designed to help people with liver failure. The therapy, which involves attaching the modified pig liver externally, filters a patient’s blood so their own livers can temporarily rest and perhaps heal.

Different enzymes can be used in the CRISPR system to modify how DNA is cut

The system uses RNA sequences to guide enzymes like Cas9 to specific spots in DNA, where they cut or modify genes. Unlike Cas9, the Cpf1 enzyme makes staggered cuts, which helps insert new DNA more cleanly.

Learn about the chemical refinement of crude oil, from cracking to reforming and blending

Just as an organism's digestive system can break down complex molecules in food into simple sugars that cells can use, cracking uses catalysts and other chemicals to break apart large hydrocarbons in crude oil into smaller molecules. These can then be chemically reshaped, combined, or purified into useful petroleum products.

Cordyceps: the fungi that turn ants into zombies

The hit show (and video game) "Last of Us" was inspired partly by real-life species of fungi that have been known to turn ants into zombies. Spores of the Cordyceps fungi are capable of penetrating the exoskeletons of arthropods, after which they break into enzymes and proliferate within the body. The fungal cells then hack the ant's nervous system and trigger compulsive climbing.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Watch how deep-sea mining equipment collects and processes polymetallic nodules—metal-rich, potato-shaped rocks—from the ocean floor and creates environmentally damaging plumes of sediments.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

Sony set the standard for cylinder-shaped batteries when it repurposed manufacturing equipment used to make rolls of magnetic recording tape.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

The Nasdaq's 'Magnificent 7' companies are responsible for roughly 40% of the Nasdaq 100 index's gains, while the remaining 93 companies account for the other 60%.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.