The 'Penicillin Girls' made mass production possible

Oxford scientists turned Fleming’s mold discovery into medicine

In 1939, a team at Oxford—including Howard Florey, Ernst Chain, and Norman Heatley—revived Fleming’s forgotten discovery. Using makeshift equipment like bedpans and milk churns, they purified enough penicillin to prove it could treat deadly infections.

Penicillin production was just behind the atom bomb in wartime priorities

By 1943, the US War Department made penicillin its second-highest priority—just after the Manhattan Project. Producing enough of the antibiotic for the D-Day invasion became a central mission of Allied science and industry.

Penicillin’s pioneers were awarded the Nobel Prize in 1945

Alexander Fleming, Howard Florey, and Ernst Chain received the 1945 Nobel Prize in Physiology or Medicine for discovering and developing penicillin.

A moldy cantaloupe supercharged penicillin production

In 1943, a moldy cantaloupe found at a market in Peoria, Illinois, yielded a strain that produced six times more penicillin. Though often credited to lab worker “Moldy Mary” Hunt, accounts differ on who actually brought in the fruit.

Penicillin was hailed as a 'wonder drug' upon its release

When penicillin became widely available in the 1940s, newspapers and doctors alike celebrated it as a “wonder drug” that could cure infections once considered fatal.

Penicillin has saved an estimated 500 million lives since its creation

Since its introduction in the 1940s, penicillin and related antibiotics are estimated to have saved around 500 million lives worldwide—making it one of the most consequential medical breakthroughs in human history.

Women's wartime suit features silk dyed with CRISPR-modified bacteria

Anna Dumitriu's bioart piece was created to commemorate the 75th anniversary of the first use of penicillin in a human patient and intends to raise awareness about the rapid development of antibiotic-resistant pathogens by using bacteria that have essentially been transformed into their pre-antibiotic era state.

Marie Curie developed and trained women to operate mobile X-ray units in World War I

The “petites Curies” allowed medical professionals to identify the severity of wounds without transporting soldiers to medical facilities, expediting treatment and saving lives. The efforts of Curie and other women led to expansions in their rights after the war.

The pharmaceutical industry evolved, in part, from the discovery of synthetic dyes

In 1856, a chemist accidentally discovered mauveine, the world’s first synthetic dye, while trying to make quinine to treat malaria. The synthetic dyes that followed helped reveal germs under microscopes, paving the way for modern imaging techniques and breakthrough treatments, such as antibiotics.

The food processing techniques developed for World War II, later repurposed for consumers

Research projects funded or sponsored by the military led to the development of active dry yeast to make bread easier to bake and an improved version of dehydrated cheese, which would be used in powdered cheese snacks. Freeze-drying, which had been used to ease the transport of blood plasma to battlefields, where it would be reconstituted with water, was later used on fruit for cereals.

Recombinant DNA technology turns microorganisms into protein factories

Genes for molecules such as insulin can be inserted into loops of bacterial DNA called plasmids and reinserted into bacteria. Once placed in fermentation tanks, these bacteria use the gene to produce these molecules, which are then harvested and purified for eventual use.

The story of the Radium Girls, who exposed the dangers of radioactive paint

After radium was discovered in 1898, companies began using radium-based paints on watch and clock dials to create a glow-in-the-dark effect. Women who worked to apply the paint were encouraged to use their lips and tongues to help create the fine point needed to draw small numbers, unknowingly poisoning themselves.

All‑female Soviet 'Night Witches' terrorized German lines with stealth bombing raids

Flying obsolete Polikarpov Po‑2 biplanes, the all-female 588th Night Bomber Regiment—dubbed “Night Witches” by terrified German troops—flew over 30,000 night missions, dropping 3,000 tons of bombs under near silence.

A 1954 outbreak at a Boston boarding school allowed scientists to isolate the measles virus

While measles was described as early as the 9th century, humanity lacked the medical technology to fight the disease until the mid-20th century. Vaccine development from the Boston outbreak in the 1960s and 1970s led to one of the most effective inoculation campaigns in history.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Doctors ignored women's pain as a nurse replaced their fentanyl with saline

This five-part podcast series, produced by Serial Productions, focuses on the experiences of women undergoing fertility treatments at a Yale clinic where a nurse secretly replaced pain medication with saline solution. This led to women experiencing excruciating pain during procedures, but the clinic downplayed or ignored their complaints.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Girl groups had a profound influence on the Beatles

The legendary Liverpool group cut their teeth playing girl group hits at the Cavern Club (including the Marvelettes' "Please Mr. Postman," which appeared on 1963's "Meet the Beatles) and even invited the Ronettes to join them on their world tour in 1966.

With no textbooks or antibiotics, this WWI surgeon pioneered facial reconstruction

New Zealand surgeon Dr. Harold Gillies made extraordinary advances in the field of reconstructive surgery during World War I and after. This 36-minute NPR podcast interviews historian Lindsey Fitzharris, author of Gillie's biography, The Facemaker, charting how the good doctor reconstructed the faces of numerous soldiers in an age before antibiotics and plastic surgery as we know it today.

Indigenous women crafted the integrated circuits for the Apollo Guidance Computer

Applying their blanket-weaving skills, over 1,000 Navajo women in New Mexico were hired to connect circuit components in intricate patterns using a microscope. Outside Boston, "rope mothers" at the Raytheon facility wove the AGC's core memory using threaded metal wires.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

The printing press spread novels widely

Johannes Gutenberg's invention of the printing press in 1440 changed how writing was reproduced. It allowed multiple manuscripts to be copied via movable type rather than by hand, making more literature more widely available. Over time, that change caused literacy rates to rise, creating a market for even more literature.

Who were the Cambridge Five

Recruited in the 1930s, the Cambridge Five infiltrated British intelligence and leaked secrets to the Soviets for decades, shaping WWII and the Cold War.

Photo 51's distinct 'X' pattern and spacing provided data to validate DNA's model

Rosalind Franklin and Raymond Gosling captured the photo after bombarding DNA fibers with X-rays and observing how the beams were deflected. The photo had a 62-hour exposure time and indicated a helical structure for DNA.

Modern Champagne owes much of its existence to one woman: Widow Clicquot

Barbe-Nicole Ponsardin, better known as the Widow Clicquot, might not have actually invented Champagne, but her innovative approach to winemaking yielded many techniques still used today. Taking over her husband’s failing business after his death, the Widow Clicquot combined business savvy and innovative thinking to make the process easier, more efficient, and, most important, more profitable.

Colonial America imported brides for their beer brewing skills

Life in the New World's English colonies was hard, so it's easy to see how these colonizers might've wanted to reach for a cold one more often than not. This article explains how beer brewing became one of the most critical skills expected in imported English wives.

Henry Ford pioneered the first moving assembly line, building on earlier iterations of the manufacturing method

Although cars existed before the Model T, manufacturing them required a group of highly specialized mechanics. The Model T was so affordable in large part because of the moving assembly line, which cut down the total manufacturing time of the car and replaced specialized workers with general laborers who performed repetitive tasks.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

When a Paris department store hesitated to sell Estée Lauder's perfume, she 'accidentally' broke a bottle, causing the smell to spread throughout the store and shoppers to start asking to buy the scent.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

Poison ivy was sent to Europe in the 1600s as an exotic, ornamental oddity, where it was purposefully grown in the English royal gardens at Kew, the Faculty of Medicine in Paris, and a few other locations.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Sony set the standard for cylinder-shaped batteries when it repurposed manufacturing equipment used to make rolls of magnetic recording tape.

The Beatles' US label rejected the band's first two singles, 'Please Please Me' and 'From Me to You,' with one executive calling the band 'dead in the water.'

Up to a million Girl Scouts sell about 200 million cookie boxes every spring, generating $800 million, largely because refusing a child is frowned upon

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

See the evolution of Ebola vaccine and treatment development.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

See the most iconic photos from four decades of LIFE magazine

Brandi Chastain, the star of the 1999 US victory over China in the 1999 Women's World Cup, was a last-second choice to take the penalty kick that sealed the victory.

Dorothy's famous entrance into Oz in 'The Wizard of Oz' relied on analog tricks, including a body double and sepia-toned paint, as much as it did on technology

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.

Double world record holder Hunter Ewen helped conquer his fear of balloons, called globophobia, by training to win Guinness World Record titles for balloon inflation.

Roughly 43 million US borrowers owe roughly $1.7T in student debt, the second-largest source of consumer debt behind mortgages.