Drug-resistant staph infection is one of the deadliest superbugs

Superbugs are bacteria and pathogens that rapidly evolve defenses against medication

Superbugs, or antibiotic-resistant bacteria, infect millions and pose a threat to global health. Developing new antibiotics is costly, offers limited profits, and struggles to outpace bacteria’s rapid evolution.

Antimicrobial resistance is responsible for 1.3 million deaths each year

Antimicrobial resistance is a global health threat, driven by the misuse and overuse of antimicrobials in humans, animals, and more. Estimates suggest superbugs could lead to $1T in healthcare costs by 2050, and the world faces a shortage of new drug development to meet the challenge.

The most critical superbug strains (as of 2024)

The World Health Organization updated its list of the highest priority pathogens known to have developed antimicrobial resistance. Topping the 2024 update is Acinetobacter baumannii, carbapenem-resistant ("CRAB"), which has a mortality rate close to 50% and has evolved defenses against last-line medications. Download the full report here.

Tips for reducing the risk of antimicrobial resistance

Antimicrobial resistance is bad news. But there are lots of things you can do to both protect yourself from superbugs and help keep the problem of antimicrobial resistance from getting worse. This page from the CDC offers clear, straightforward guidelines that can help keep you—and your loved ones—healthy.

Sepsis is the leading cause of death in hospitals

Sepsis is the result of an overly aggressive immune system trying to combat infection, triggering inflammation throughout the body. After it begins, each passing hour increases the risk of death by 4% to 9%, and an estimated 350,000 people die from the condition in the US each year.

Mapping the spread of a dangerous fungus growing in US healthcare facilities

Explore the data showing how the fungus C. auris has spread in the US, with more than 10,000 reported cases since 2016. Recommended steps to prevent infections and limit their spread have been successful in some areas, but infection control remains complicated because the fungus is often now multidrug-resistant.

Resistant infections are no longer isolated and can spread worldwide

What does the rise of antibiotic resistance mean in practical terms? Maryn McKenna is a journalist at the forefront of covering antibiotic resistance since 2007. In this TED talk, McKenna lays out the very real consequences of antibiotic resistance—and what needs to be done to address the problem.

An estimated 1% of DNA mutations in bacteria can produce more dangerous strains

Researchers have developed a technique to monitor these mutations in real time. Using this technology, scientists found that mutations occur at a steady rate, with 1% leading to potentially deadly changes.

Mosquitoes top the ranking of the world's deadliest animals

Mosquitos kill about 760,000 people every year. The vast majority of those deaths are caused by malaria, which is transmitted and spread by the Anopheles mosquito. The second-place deadliest animal title goes to snakes, with an estimated human death toll of around 100,000 annually.

Corynebacterium species are particularly responsible for our funky smell

Myriad bacteria contribute to our body odor, but research suggests that Corynebacterium species are strongly associated with the bad smells emanating from adults. Staphylococcus and Cutibacterium genera may also play leading roles.

Penicillin ended scarlet fever’s deadly threat to children

Between 1840 and 1883, scarlet fever was among the leading causes of childhood death in the United States, with case fatality rates ranging from 15% to 30%. Today, thanks to antibiotics like penicillin, the mortality rate is below 1%.

Secondary complications from measles in children range across the whole body

The most serious effects of a measles infection, particularly in young children, come from its attack on the immune system. This leaves the whole body vulnerable to follow-on diseases, with some of the most serious including respiratory conditions, encephalitis, and more.

Black mold isn’t more worrisome than other colors of mold

Black mold typically refers to Stachybotrys chartarum, a mold that commonly appears in damp or water-damaged areas of the home. Black mold—and other molds—won’t typically make otherwise healthy people ill, and all molds should be treated the same with respect to health risks and removal. If you have mold allergies, mold can cause an allergic response, and it can trigger asthma attacks for people with asthma. If you have a compromised immune system, then black mold exposure can also cause a fungal infection in your airways or elsewhere in the body.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

Scleroderma, which causes skin to harden and scar, has no FDA-approved treatment

It's an autoimmune disease that disproportionately causes worse complications in African American people for unknown reasons. It causes the body to overproduce collagen after the immune system attacks the body's own connective tissue, leading to excess collagen deposits and restricted blood circulation as small blood vessels are damaged. It can damage various organs, including the lungs.

HFMD can survive on surfaces for days at a time

That's why the virus can be transmitted via fomites—surfaces that have virus on them like doorknobs, kids toys, etc. These viruses are resilient—they are often even resistant to freezing (and are frequently stored at freezing temperatures in lab settings).

Prostate cancer is both manageable and the second-deadliest cancer for men

One in 44 men in the US will die from prostate cancer, while one in eight will be diagnosed with it. Commonly viewed as the safest cancer to have, screenings can save lives—but they can also cause complications for otherwise benign cases of the disease.

Norovirus is the leading cause of food poisoning in the US

The illness is typically transmitted when virus-laden feces gets into another person’s mouth. That occurs when people do not properly wash their hands, contaminating food or surfaces.

Learn about swimmer's ear, which sickens 1 in 10 Americans

This outer ear infection—in the tube leading from the ear opening to the eardrum—is usually caused by bacteria. Formally called otitis externa, this condition is commonly called swimmer's ear because microbes can enter the ear canal while swimming.

A macrophage can eat 100 bacteria, on average, before it's exhausted

These specialized immune cells are first responders during inflammation, responding to a threat or injury and then performing other inflammatory response tasks, including summoning neutrophils to help attack invaders.

Research suggests the cleanliness of the ISS may make astronauts unhealthy

The International Space Station's sterile conditions deprive astronauts of the opportunity to strengthen their immune systems through microbial exposure. To address this problem, future missions may use probiotic-based cleaners and foster diverse microbes in space habitats.

Ringworm is caused by a fungus, not a worm

Ringworm, formally known as tinea and known for its red circular rash, is responsible for about 325 million infections at any given time—comprising roughly half the world’s fungal skin infection burden. It’s caused by a type of fungus called a dermatophyte, which also causes athlete’s foot and jock itch. Doctors typically prescribe antifungal tablets or powders to stamp out these fungal invaders.

Malaria case in Maryland stumped doctors in 2023—leading to the wrong treatment

When the state had its first locally acquired malaria case in over 40 years, the patient was misdiagnosed with a more common tick-borne infection, leading to weeks-long treatment for the wrong infection. The patient had symptoms that could occur with malaria or with babesiosis, a disease caused by Babesia parasites and transmitted by ticks in the US.

Understanding R0, a measure of how contagious a pathogen is

The R0 value is a basic measure of how many people an infected person will transmit a pathogen to, on average. If R0 is less than 1, transmission dies out; if greater than 1, an outbreak is likely. Measles has one of the highest known R0 values at almost 18, meaning that after four transmission steps, more than 100,000 people could be infected.

The disease no one survives (yet)

Creutzfeldt-Jakob disease is currently incurable and can cause one's death within months of symptoms appearing. It involves misfolded proteins that, for some reason yet unknown to science, aren't cleared by the brain as typical and instead trigger similar proteins to misfold. These malformed major prion proteins—prion being a portmanteau of protein and infection—clump inside nerve cells, blocking signals crucial to processes ranging from speaking to organ function.

Leprosy bacteria are sometimes grown on mouse feet for research

The main leprosy-causing bacterium can't be grown in a petri dish, so the disease is challenging to study in the lab. For research purposes, it has been grown in the foot pads of mice.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Between 10 million and 50 million people in the US develop rashes from poison ivy, poison sumac, and poison oak each year.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

11 people died from firework injuries in the US in 2024.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Lesser-known phobias include turophobia, or the fear of cheese, and nomophobia, the fear of being without your cell phone.

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

Art theft is the third-largest source of criminal revenues worldwide, thanks in part to the subjective nature of valuing a work of art.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Neutron stars, the remains of some massive stars after they explode in a supernova, are the densest directly observable objects in the universe.

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

US consumers collectively owe more than $1T to credit card companies—almost as much as they owe in auto loans.

The Nasdaq's 'Magnificent 7' companies are responsible for roughly 40% of the Nasdaq 100 index's gains, while the remaining 93 companies account for the other 60%.

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in terms of casualties, forces mobilized, and displacement of civilians.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year