Postmenopause is a stage lasting roughly a third of a woman's life

Perimenopause, which typically occurs in a woman's mid-40s, precedes menopause

Sometimes referred to as the menopausal transition, this time period often lasts around 4 years as the ovaries' production of the reproductive hormones progesterone and estrogen decline. It may be accompanied by mental and physical symptoms including irregular periods, hot flashes, sleep issues, mood swings, and alterations to a woman's sex drive.

Menopause is defined as 12 months without a period

Menopause is officially when a woman stops getting her period, meaning she has stopped ovulating and can no longer get pregnant. A woman has to go a full year without bleeding or spotting to know she has hit menopause.

How menopause affects mental health

Menopause, a natural biological process, occurs in three stages: perimenopause (hormone fluctuations), menopause (end of menstrual cycles), and postmenopause (12 months without menstruation). Hormonal shifts during this time can affect neurotransmitters, increasing the risk of mood disorders.

Perimenopause can last as long as 8 years

Typically lasting around four years, beginning around age 45, some women experience it as early as their 30s. Smoking and thyroid disease are factors that can trigger early perimenopause. Early menopause, which can increase health risks, occurs in about 5% of women. Researchers are still investigating why it occurs.

By 2030, roughly 6% of the world's population will be in menopause

An estimated 25 million women pass through menopause annually, with a projected increase in the number of women in menopause in both lower-resource and higher-income populations in the years ahead, highlighting the social and economic value of focusing on menopause care.

Menopause is a hormonal transition point, like puberty

Yet menopause isn't talked about as much. In this podcast episode by Houston Methodist, a Texas-based hospital, the host speaks with a gynecologist with a specialization in menopausal medicine about what menopause really is, and how women and the people in their lives can navigate this next life stage.

Menopause and perimenopause symptoms may affect both the mind and body

Women going through these aging transitions may experience some common physical and mental symptoms to varying degrees, including hot flashes, bladder control issues, brain fog, and vaginal dryness. This article dives into some of the most common symptoms women might expect during perimenopause, plus what they can do to relieve them.

Late-onset menopause lowers osteoporosis risks, but heightens the risks for certain cancers

Defined as when a woman starts to experience perimenopause after age 55, this delayed menopause onset is linked to elevated risk of developing breast, ovarian, and uterine cancers.

The gaps in menopause research and their effects

Nearly all studies (99%) researching the biology of aging don’t consider menopause in their setup. A Harvard professor noted that about 75% of aging-related diseases are likely influenced by menopause. In this article, she discusses how gaps in research are negatively impacting how the medical system can effectively treat aging women. Read her analysis of the issue here.

Health problems are being misdiagnosed as perimenopause symptoms

Symptoms of menopause and perimenopause (the premenopause period) can be varied enough that clinicians dismiss them in patients in their mid-30s and onward as just a symptom of hormone level change. In this story, a woman's itching was dismissed as a hormonal change, but after two years and 11 separate doctor consultations, was diagnosed as cancer. (Some users may experience a paywall.)

Treatment-induced menopause is menopause induced by surgery or medicine

Chemotherapy and radiation, as well as oophorectomy (a surgical procedure that removes the ovaries) and a radical hysterectomy can cause a woman to become menopausal. Women that go through medical menopause experience the same symptoms as women that experience menopause caused by natural hormonal cycles.

Menopause hormone therapy infuses the body with estrogen after the body's natural levels drop

The treatments can treat symptoms like hot flashes and vaginal dryness at varying doses. Progestogen, another hormone, is also typically prescribed with estrogen because estrogen alone can thicken the uterus lining, which elevates the risk of developing endometrial cancer.

Scientists have not yet answered what the evolutionary benefit may be of menopause

Few animals are known to experience menopause, raising questions about why it would be evolutionarily advantageous to have women survive past their reproductive years. One leading hypothesis is the grandmother hypothesis—older women and other species known to experience menopause, like whales, can aid families and pass down knowledge to future generations.

'Menobelly' is real, with more fat stored around the abdomen as estrogen levels drop

The way fat is carried in the body shifts with menopause, with those pounds increasingly settling around the abdomen instead of the hips and thighs. Exacerbating this phenomenon, muscle mass also begins to decline, so calories stick around longer than usual. Resistance training, including push-ups and planks, alongside a heavier protein diet can help.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Some argue that annuities are particularly good options for women

Women live longer than men, meaning they’ll likely be retired for longer. Annuities can provide them with a guaranteed income stream during their retirement years, even if the rest of their retirement plan doesn’t last.

Final life insurance is most common for people over the age of 50

Final expense life insurance is a type of life insurance where, instead of paying a sum of money to your beneficiaries after death, the insurance covers the expenses for your funeral, burial, and any end-of-life care.

How women grow tiny humans inside of them

Pregnancy is a complex biological journey, lasting about 40 weeks. When a sperm fertilizes an egg, that event triggers intricate cellular and hormonal processes, driven by hardwired cellular instructions, which lead to cell division, differentiation, and development—ultimately culminating in the birth of a baby.

Post-polio syndrome occurs decades after infection but isn't contagious

Affecting adults who contracted polio as children, this disorder can occur 15 to 40 years later, leading to slow, irreversible muscle weakening. Some research estimates that between 25% and 40% of polio survivors go on to develop this condition.

Health span: The number of years one is active and disease-free

As scientific advances continue to extend the average human lifespan, many are now turning their attention toward extending "health span." The ultimate goal would be to extend one's health span to match one's lifespan, which would necessitate a shift in focus toward the pursuit of healthy aging. (Some users may experience a paywall.)

Premarin, the hormone medication derived from pregnant horses, is 'PREgnant MARes urINe'

Scientists in the late 1920s and early 1930s discovered estrogens could be extracted from human placenta, and then isolated it from the urine of pregnant women. But researchers discovered the urine of pregnant horses had similar substances and the horse product was much easier to collect in significant amounts—leading to Premarin.

Depression is much more than sadness—and isn't fleeting

The American Psychiatric Association's DSM-5—used for defining diagnoses—says a person must be experiencing five or more symptoms of depression most of the day over at least two weeks. Research indicates older people are less likely than younger people to meet that depression benchmark, though this article says they still often have at least several of the depression symptoms.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

Cancer is typically described by one of five stages

Stage 0 is in situ, meaning abnormal cells haven’t spread, while Stage 1 is further progressed but remains localized to the origin. Stage 2 and 3 show increasing tumor size and spread to nearby lymph nodes or tissues. Stage 4 indicates metastasis, meaning cancer has spread to distant organs.

The story of Billie Holiday's final performance

In her final days, Holiday was still performing—often at clubs outside of New York—though she was struggling with cirrhosis, an effect of her alcoholism. This excerpt from Paul Anderson's "Bitter Crop: the Heartache and Triumph of Billie Holiday's Final Year" details her final show in Lowell, Massachusetts, offering a tragic portrait of the singer running out of steam.

Anticipatory grief describes experiencing sorrow ahead of a loss

All-consuming anticipatory grief—like if you know a loved one will soon die from a chronic illness—can be disabling. Seeking exercise, healthy food, hobbies, and trying to toggle between thinking about an upcoming loss and focusing on other matters is important for promoting health.

About two-thirds of humans lose their ability to produce lactase after weaning

Lactase is an enzyme that digests lactose—a sugar in milk and dairy products. While genetics strongly determines lactase persistence, factors like famine, disease exposure, and gut bacteria also influence symptoms and evolution.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Brandi Chastain, the star of the 1999 US victory over China in the 1999 Women's World Cup, was a last-second choice to take the penalty kick that sealed the victory.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

The USPS spent $3.97B in 2024, accounting for .058% of the federal budget.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

While El Niño moves warm Pacific Ocean waters east along the equator, La Niña moves them west, shifting where rainfall will become more common for months.

A century of Billboard issues documenting the evolution of popular music.

US housing costs have risen by roughly 175% between 1991 and 2026—but a growing number of Gen Zers are becoming homeowners anyway. In 2025, 4% of homebuyers were Gen Z, up from 3% the year before.

Neutron stars, the remains of some massive stars after they explode in a supernova, are the densest directly observable objects in the universe.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Between 10 million and 50 million people in the US develop rashes from poison ivy, poison sumac, and poison oak each year.

Play the role of a student in a game where you try to navigate college and remain debt-free, selecting different income levels, high school experience, race, ethnicity, and more.

Take a 3D tour of the Hajj, Islam's annual pilgrimage to Mecca, undertaken by over 1.5 million Muslims.

The distributor behind 'Rocky Horror' pulled the film from its scheduled national release, believing it would be a failure, though it eventually amassed a dedicated fanbase through midnight showings, a trend that continues over 50 years later.

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.

Watch contemporary footage covering the US-backed Shah of Iran fleeing the country in the face of the 1979 Iranian Revolution

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

Some coin denominations have ridges etched on their sides, partly to prevent counterfeiting, in a practice called 'reeding.'