Ancestry testing matches DNA to known genetic variants found in specific ancestries

Around 5 million of our 3 billion DNA letters differ between individuals

Genetic testing examines gene variants to help explain disease symptoms. It explores how genetic differences between individuals can be used to understand risks of developing diseases like Huntington's Disease or passing variants linked to disease onto offspring.

How uploading your consumer genetic testing could lead to a distant relative's arrest

This podcast includes a discussion about how law enforcement can compare DNA samples from a crime scene against voluntarily uploaded DNA on consumer genealogy databases to close cases. Investigators can and have cross-referenced a suspect's crime scene DNA with that of a suspect's relatives who happened to have chosen to upload their genetic information to an open-source genealogy database.

Spotify and AncestryDNA launched a genetic music playlist offering

The playlist offering in 2018 purported to make a unique playlist based on cultural inheritance. The service required users to link their account, select the top five ethnic regions from their AncestryDNA results, and then Spotify would create the playlist based on that data.

The first criminal conviction through the use of DNA evidence was in 1988

Chromosomes contain markers where short DNA sequences repeat a variable number of times from person to person. A DNA profile is constructed by identifying the number of repeats across 20 regions throughout a genome, which can be compared against a database. DNA paternity tests work similarly by comparing markers between children and their fathers. (Some readers may experience a paywall.)

Why your dog’s DNA isn’t destiny

DNA tests tell people about their pet’s breed and attempt to predict things about its behavior and health. But for all that these tests might provide some interesting results, they need to be taken with caution. Here's a look at what we can and can't learn from our pets' DNA.

The lack of diversity in DNA databases limits their applications

European ancestry dominates genetic research, hindering the usage of genetic databases for precision medicine for other groups, including African Americans, who face higher health risks due to genetic variants. Many Indigenous communities have also resisted genetic research due to past exploitation. (Some readers may experience a paywall.)

US regulators have approved an at-home genetic test looking for BRCA gene mutations

The direct-to-consumer genetic test, approved by US regulators in 2018, examines 3 out of the more than 1,000 known breast cancer-linked genetic mutations. It looks for genetic variations that can increase risk for breast, ovarian, and other cancers. These mutations are most commonly found among Jewish people with Eastern European ancestry.

Glowing chemicals allow scientists to read DNA like a barcode

The process of determining the order of nitrogenous bases in DNA involves first cutting the DNA into fragments, which are duplicated multiple times using bacteria. Fluorescently labeled terminator bases are added to fragments, which are sorted by length and read via laser to reconstruct the sequence.

Explore the differences between healthy and cancerous cells using a DNA microarray

In this simulation, you will learn how scientists use microarrays to experiment on thousands of genes at the same time. By determining which genes are on or off, users can identify those that contribute to cancer formation.

Modern genetic testing stems from a 1950s discovery about the cause of Down syndrome

Scientists found that an additional copy of chromosome 21 causes the disease and developed an approach to stain chromosomes so they could be manually sorted and counted, which is called karyotyping. The breakthrough discovery by Marthe Gautier, a young French doctor and cytogenetics researcher, was appropriated by a male colleague, who listed himself as the lead author of the study reporting the finding.

23andMe declared bankruptcy in March 2025

The consumer genetic testing company, which offered detailed genetic profiles from users' saliva samples, suffered financially after they suffered a major data breach affecting almost 7 million customers in 2023. Its flagship product was a one-time genetic analysis which also made retention of users challenging.

All publicly available DNA sequences are available at GenBank

The National Institutes of Health's database stores comprehensive, annotated DNA sequences as part of the International Nucleotide Sequence Database Collaboration. It encourages unrestricted data access within the scientific community while allowing submitters to retain intellectual property rights over their data.

The oldest DNA recovered so far is 2 million years old

The oldest DNA recovered so far is about 2 million years old and has given scientists an unadulterated peek into ancient history. This nine-minute video explores the findings and implications of the DNA, which was pulled from frozen soil in...

Svante Pääbo's life work was to discover the Neanderthal in our genes

Geneticist Svante Paabo reconstructed the genome of long-extinct human relatives, showing we have more in common with Neandertals than previously thought. Read up on his research and its impact on the wider scientific community.

Biological aging tests assess the breakdown of physiological systems

Known as aging clocks, these tests compare various metrics, like DNA methylation patterns and protein profiles, to healthy baselines. However, the non-uniformity of these baselines across individuals limits testing accuracy and prevents their clinical use.

Environmental DNA monitoring can help detect the presence of invasive species

Genetic material that organisms deposit into water, soil, or air can be identified by analyzing samples from each environment, allowing land managers to more reliably detect and track organisms than visual surveys alone. eDNA has been used to develop early warning surveillance systems for various invasive marine species.

Allergy tests identify antibodies, but not whether allergy symptoms may appear

Skin prick tests and blood tests, the two most common allergy tests, both detect the presence of allergen-specific antibodies. But just because the body has those antibodies doesn’t mean that a person is “allergic” to a substance or that they will develop symptoms of an allergy when encountering the substance. Allergists work with families to interpret the results and sometimes combine that data with approaches including exposure challenges—giving someone a tiny bit of the food or substance they may be allergic to—under medical supervision.

Like fingerprints, brain anatomy is unique too

Researchers have discovered that a combination of experiences and genetic factors shape the anatomy of the human brain. They found even quick experiences affect the brain’s genetic makeup, which—over time—means every person develops a completely unique brain anatomy. While brain imaging could be used to identify individuals, it remains much more expensive than fingerprinting for now. Read to found out more about this study from the University of Zurich.

Your DNA may determine whether you like coffee or tea

Whether people prefer coffee or tea may boil down to a matter of taste genetics. People with a version of a gene that increases sensitivity to the bitter flavor of caffeine tend to be coffee drinkers, according to a report. Read on for more.

How do genetics work?

Perhaps you have your mother’s hair or your grandfather’s eyes. How did you get these traits and not others? Learn how genetics work in this online video game.

Explore the independent lines of evidence behind the theory of evolution

Gradual changes in organisms have been directly observed through artificial selection—humans purposely selecting organisms to breed to pass on specific traits—and in organisms with short lifespans, such as insects and microbes. Analyses of DNA and anatomical structures across different species, as well as fossil records, also reveal ancient shared ancestry consistent with natural selection.

Most people with East Asian ancestry are genetically predisposed to be less smelly

A gene variant found in 80%-95% of individuals with East Asian ancestry reduces armpit bacteria and related odors. People with this nonfunctioning ABCC11 gene variant lack a protein that transports molecules, including sweat, across cellular membranes, so their armpits are starved of sweat that bacteria may have metabolized to help them multiply.

What you can learn from your last name

Surnames are a powerful source of information, giving insight into one’s ancestral history and cultural heritage. This article explores the specifics, giving examples of how one’s last name reveals one's ethnic background or even what your ancestors did for a living. Discover more about surnames around the world, and reflect on your own personal history.

Can you guess which ancient human skull is which?

When scientists discover a new fossil skull, they compare it to skulls that have already been identified as particular early human species. In this activity, you get the chance to be the scientist! Choose a mystery skull to identify by clicking on it.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

A brief history of human blood groups

The blood group that determines whether you have type A, B, AB, or O blood was discovered near the turn of the 20th century. This short academic article dives into three main theories about the evolution and emergence of blood groups, the exact nature of which remains unclear.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

When you complete a CAPTCHA on a website to prove you are human, you may be unknowingly training algorithms for self-driving cars, whose systems require training data to help identify crosswalks, bicycles, and other outdoor objects.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Meet the 56 signers of the Declaration of Independence—most of whom didn't put pen to paper until August 2, 1776—and see their original signatures.

The 2026 Ebola outbreak is hampered by a lack of vaccine against the species of the virus, heightening the need for rapid tests to aid in disease control.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Search a massive database of over 4 decades of clues from the TV quiz show 'Jeopardy!'

Poison ivy's rash-causing compound is found in the plant's roots, stem, and leaves—so coming into contact with any part of the plant can lead to rashes for the 85% of people who are allergic to it.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.

The Brothers Grimm were lawyers before they were storytellers, but became interested in fairy tales as they began investigating how rules and customs had been passed down through cultures.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

Some coin denominations have ridges etched on their sides, partly to prevent counterfeiting, in a practice called 'reeding.'

Venture capital is a form of funding provided to early-stage companies with high growth potential, typically in exchange for an equity (or ownership) stake

The term 'algorithm' originated from the Latinized name of al-Khwārizmī, a 9th-century mathematician whose works introduced Arabic numerals and the decimal-based numeral system to Europe and whose treatise 'Al-Jabr' gave algebra its name.