Model organisms like yeast, mice, and flies help scientists decode the human body

Fruit fly experiments helped identify genes responsible for major body development

The insects' fast life cycle and affordability have allowed geneticists to quickly identify which genes are responsible for limbs, eyes, and other body structures by inducing mutations. The same genes may be responsible for different parts of a species' body, such as limb-building genes being responsible for wing pigmentation in butterflies.

Long-term evolution experiments use microbe's short generations to speed up selection

With quick generations of microbes, scientists can speed up the evolutionary process, with projects like the LTEE in California running for 40 years and generating 80,000 generations of E. coli.

Humans are more genetically similar to cats than to dogs

While humans are not closely related to either cats or dogs from an evolutionary standpoint, scientists find that human and cat chromosomes are organized more similarly to each other than human and dog chromosomes, making cats a better model for studying human diseases.

Synthetic biology can prevent extinction by creating create disease-resilient plants and animals

Through gene editing and the deployment of artificial cells, scientists can leverage learnings from the genetic sequencing of animals with known resistances to protect endangered species. Gene editing of certain species, such as mosquitoes, can also reduce their ability to spread diseases like malaria between humans.

Research studies can be conducted inside or outside of living samples

While "in vitro" experiments occur outside living organisms for cost-effectiveness, "in vivo" experiments take place inside them, providing real-life insights at a higher cost and with increased ethical concerns. Alternatively, "in silico" methods use computational simulations.

The Human Genome Project spawned numerous spinoff genetics projects

The Human Genome Project led to the development of techniques later applied to projects in microbial and plant biology, epigenomics, environmental and cancer genomes, and more. In the spirit of the HGP, data from these projects has been made freely available to develop new technologies.

Pigs are preferred for xenografts because of their size and low disease risk

Pigs are of particular interest for xenotransplants because the animals are close to human size, are easily raised in captivity, and have large litters. They’re already routined killed for food and they’re less genetically related to humans than nonhuman primates, which reduces disease transmission risks and some researchers’ ethical concerns.

Cells modify their internal spacing to improve biochemical reaction efficiencies

Studies involving microscopy and genetic engineering tools in yeast and human cells show ribosomes act as crowding agents—much like packing peanuts—and their concentrations are actively tuned to alter the rate of cellular functions. However, these concentrations and cell crowding levels vary across different tissues and cell types.

Some animals have little or no bacterial populations in their gut

Gut microbiomes are essential to human health, but many animals have a much smaller, transient, or even nonexistent microbiome. The discoveries have advanced our understanding of the evolution of the human microbiome.

Leprosy bacteria are sometimes grown on mouse feet for research

The main leprosy-causing bacterium can't be grown in a petri dish, so the disease is challenging to study in the lab. For research purposes, it has been grown in the foot pads of mice.

Some organisms are composed of a single cell visible to the naked eye

By incorporating tough, cellulose-rich cell walls, rapid movement of molecules via cytoplasmic streaming, and other biological techniques, some unicellular organisms can bypass the physical limitations that restrict the size of cells. Organisms such as the Stentor coeruleus and Acetabularia can be seen without microscopes.

The human body in 3D

Zygote Body is a free human anatomy tool that allows users to explore the intricacies of the human body in stunning detail. With the click of a mouse, users can isolate by body system or view anatomical structures from any angle. Check out this...

Explore the differences between healthy and cancerous cells using a DNA microarray

In this simulation, you will learn how scientists use microarrays to experiment on thousands of genes at the same time. By determining which genes are on or off, users can identify those that contribute to cancer formation.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Organoids: 3D organs grown from stem cells in the lab

An organoid is a three-dimensional construct composed of multiple cell types that originate from stem cells that can simulate the architecture and functionality of native organs. One big benefit of these lab-grown organs is that drug candidates can be tested in model systems without needing live patients.

Bacteria helped scientists realize that DNA was the hereditary molecule, not proteins

Until the mid-1900s, most scientists believed genes were made of proteins, which were known to act as enzymes, hormones, and other chemicals that mediated an organism's traits. The Avery-MacLeod-McCarty and that benign bacteria could be made lethal, where the inherited factor that caused bacterial transformation contained DNA.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Anthropic's interpretability team discusses how AI models' thinking mimics biology

Just as humans engage in complex behaviors to survive and reproduce, teams of experts in neuroscience, virology, mathematics, and other disciplines argue that large language models develop complex mechanisms to achieve their goals. These mechanisms can be manipulated to assess how they modify outputs—much like stimulating individual neurons—to uncover how LLMs "think."

Bacteria have been genetically engineered to bioluminesce when wine has spoiled

Developed by researchers at Hebrew University, the method involves the firefly enzyme luciferase, which emits light from within bacteria expressing when they are in the presence of acetic acid vapors produced by wine. The process provides affordable, on-site, real-time monitoring of fermentation quality.

Fecal transplants can help treat infections

Fecal transplants aim to transplant healthy gut bacteria into ill patients by transferring (literally) samples of human waste from a healthy patient to a sick patient. The technique has been shown to cure otherwise deadly Clostridioides difficile (C. diff) infections and is being studied for a range of other uses.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Biological aging tests assess the breakdown of physiological systems

Known as aging clocks, these tests compare various metrics, like DNA methylation patterns and protein profiles, to healthy baselines. However, the non-uniformity of these baselines across individuals limits testing accuracy and prevents their clinical use.

You can sign up to donate your body to science

It's a separate process to donate your body for medical research; you usually must contact a whole-body donation program directly. Bodies can be donated for medical research, for forensic analysis research, or for medical students to work with as they learn anatomy and surgery, among other purposes. Learn more about numerous accredited organizations that provide human bodies, organs, and tissues to medical researchers and students.

Researchers use the brain's ability to edit memories to explore memory deletion

Scientists have successfully implanted false memories in mice after studying how the editing process works in the brain. Beyond potentially deleting memories in those with PTSD, upcoming research may allow clinicians to forecast the onset of neurodegenerative diseases.

Efforts to create disease-sniffing capabilities for phones still can't match dogs

In this video, a scientist explains why dogs remain leaders in olfactory capabilities, outpacing technology. Scientists have attempted to create artificial "e-noses" for phones to detect early signs of disease, but so far they have not been successful.

Parasites have circadian rhythms, too

Researchers are working to unravel how circadian rhythms of parasites and their hosts affect one another. They’re investigating how to potentially target and disrupt those clocks for disease treatments.

Explore 3D models of some of the most dangerous viruses

Everyone has come in contact with common viruses—typically something like influenza (the common flu)—but sometimes they encounter more dangerous strains. While we're familiar with the symptoms that manifest, it wasn't until the advent of advanced microscopy that scientists could pin down the exact structure and behavior of various viruses.

Cells can last in the human body from days to a person's entire life

Despite claims that a person's body replaces itself every seven to 10 years, the rate at which cells die and are replaced varies by cell type. Gastrointestinal cells that line the digestive tract and stomach last only a few days, while some heart muscle cells and most neurons are around from birth until death.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

Scientists have struggled to pin down Ebola's natural reservoir species for decades, but the available evidence suggests that it's very likely fruit and insect-eating bats found in Africa.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

Browse a detailed visual analysis of over 200,000 similes—comparisons that often use 'like' or 'as'—from popular fiction to see how frequently writers the same idiomatic expressions.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Play the role of a student in a game where you try to navigate college and remain debt-free, selecting different income levels, high school experience, race, ethnicity, and more.