Some organisms are composed of a single cell visible to the naked eye

The secret lives of cells

Cutting-edge microscopy has revealed previously unseen interactions of biological molecules within their cellular environment, enabling scientists to observe and analyze the molecules in a holistic view. This podcast explains the minute advancements made over the last few decades in observing cells, revealing how scientists have come and what the future holds for the field.

Cells cannot grow forever due to escalating inefficiency in transporting chemicals

As cells get larger, their volume grows much faster than the surface area through which nutrients and waste products pass, creating a bottleneck that eventually causes cells to die. This forces nearly all organisms visible to the naked eye to comprise enormous numbers of smaller cells, such as the approximately 30 trillion found in the average adult human.

Cells are categorized by the presence of contained genetic material and other organelles

While prokaryotes contain one or more cells with free-floating genetic material in a region called the nucleoid, eukaryotes possess a nucleus specialized for DNA storage. Plant cells possess cell walls—a reinforced structure surrounding their membrane—made of cellulose, while fungal cell walls contain chitin. Animal cells have lysosomes housing enzymes that break down biomolecules. (Some readers may experience a paywall.)

Explore what each organelle does within various types of cells

In "Cell Anatomy Viewer," users can explore interactive illustrations of animal, plant, fungal, and bacterial cells. Clicking on an organelle, such as a lysosome, the nucleolus, or the Golgi complex, provides descriptions of its characteristics and functions.

Cell theory originated from microscopic observations of cork and dental plaque

In the mid-1600s, Robert Hooke identified compartment-like structures—which he called cells—in cork, and Anton van Leeuwenhoek discovered bacteria in samples of his dental scrapings. Almost 200 years later, Matthias Schleiden and Theodor Schwann showed that plants and animals, respectively, are composed of cells, proving that cells are the foundation of all living things.

Meet Cystisoma, the 7-inch crustacean with eyes for a head

In deep midwater, roughly 1,000 feet below the water's surface, completely transparent Cystisoma hide in plain sight from predators. Their retinas are splayed out thin across their disproportionately large eyes to avoid detection, and their entire bodies are transparent, difficult to see even as they are held in the palm of your hand. Learn more about the creatures here.

Adhesion molecules and intercellular junctions allow cells to connect together

While some organic structures are mostly composed of non-cellular components (e.g., collagen and calcium phosphate minerals in bones), tissues and organs composed of connected cells rely on specialized proteins and connections to create watertight seals that protect cells within the interior from environmental molecules.

View a gallery of bioluminescent organisms, including jellyfish and mushrooms

Some species produce a quick flash of light, while others glow steadily with an eerie glow, often to seek attention or in response to being disturbed. Snails, worms, fungi, and other organisms highlight that this ability evolved independently, rather than from one common ancestor.

Single-cell organisms have circadian clocks that direct daily biochemical routines

Cyanobacteria, a type of light-sensitive bacteria, use this clock to signal when to alternate between making organic compounds through photosynthesis and when to convert atmospheric nitrogen into usable ammonia. Upregulating photosynthetic machinery before dawn helps ensure efficient photosynthesis.

View the fluorescently stained internal structures of a tardigrade

The photograph won the Olympus Global Life Science Light Microscopy Americas regional award in 2019. Using chemicals from biofluorescent organisms, the image illuminates internal structures with multiple hues in an otherwise mostly colorless organism.

Lining up every microbe on Earth would stretch to about 105,000 light-years

There are about 10²⁷ such organisms on the planet, many of which are adapted to produce energy through uncommon reactions in unconventional environments, such as within rocks or near volcanoes on the ocean floor. Studies of these organisms have reframed astrobiologists' search for life beyond Earth by broadening the parameters under which life can exist.

Explore the abundance of different types of cells in the human body

Lacking a nucleus and other organelles to maximize space for oxygen-carrying hemoglobin and enhance maneuverability through narrow capillaries, there are about four times as many red blood cells and platelets as all other cell types in the body combined. However, about half of the body's cell biomass consists of skeletal myocytes, or muscle fibers.

Cells modify their internal spacing to improve biochemical reaction efficiencies

Studies involving microscopy and genetic engineering tools in yeast and human cells show ribosomes act as crowding agents—much like packing peanuts—and their concentrations are actively tuned to alter the rate of cellular functions. However, these concentrations and cell crowding levels vary across different tissues and cell types.

Model organisms like yeast, mice, and flies help scientists decode the human body

Some species are used to quickly study the effects of human diseases and treatments because they are short-lived and have similar systems to those found in humans. Bacteria, like E. coli, have been used as human proxies given their rapid growth and ease of genetic manipulability.

The mass of a cell can be measured using hollow, vibrating beams

In 2010, scientists at MIT constructed a U-shaped device that vibrates like a guitar string with an internal fluid channel. As cells and bacteria pass through the device, its rate of vibration shifts, with greater mass creating larger shifts.

Watch a salamander grow from fertilization to hatching

New microscopy techniques have allowed scientists to image the development of animal embryos with unprecedented detail. This six-minute time-lapse reveals the development of a salamander from initial fertilization to hatching from an egg.

Evolution doesn't want you to see these animals

Invisibility is an oft-coveted superpower that many creatures throughout the animal kingdom have evolved to mimic through transparent camouflage. This article explores the science of this seemingly magical ability. The two critical ingredients in...

The anatomy of coral polyps, whose mouths consume food and expel waste

The mouth is surrounded by tentacles that help clear away debris and defend the organism, using stinging cells called nematocysts that resemble those of jellyfish. Connective tissue called coenosarc connects individual polyps within colonies and allows them to share nutrients.

Unprecedented imaging of the Vibrio bacteria, published in 2026, may highlight new treatment targets

Researchers have produced the most detailed image ever of a key part of the Vibrio bacteria—the cause of cholera—known as the sheathed flagellum, which helps it move.

Organisms can possess multiple unique sets of DNA in one body

Genetic chimeras can result when cells with different DNA combine, such as when two sperm cells fertilize two egg cells, creating two embryos that then merge. In mosaicism, mutations arise within an organism after conception and can spread through cell division, resulting in diseases and forming genetically distinct anatomy.

About 1,500 species of tardigrades have been identified by their unique physiology

Freshwater-bound eutardigrades live on mosses and lichens and are distinguished by variations in the shape and number of claws at the end of their legs. Marine heterotardigrades, which live on algae and deep-sea sediments, have been observed to possess feathers, inflatable appendages, and flagpole-like tails.

Stem cells have the ability to self-renew

Stem cells have remarkable potential for new medical therapies. But to understand what makes stem cells so special, you must understand exactly what they are, and what they’re capable of doing. This page offers an accessible introduction to stem cell biology and their unique properties.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

Learn how to build your own vivarium

Creating a self-contained habitat for plants and microscopic animals requires a careful balance of organisms that maintain a cycle of water, nutrients, and other chemicals throughout. Bottlenecks in these cycles are mitigated through careful construction, such as incorporating a drainage layer to effectively manage water.

How does food move through the body?

Food passes through the digestive system via muscle movement known as peristalsis, during which a rippling contraction slowly pushes content through tubular organs, such as the esophagus and intestines. This is similar to what happens when one squeezes a tube of toothpaste, contracting the tube behind the content and forcing the tube in front of the content to expand, allowing the content to move forward.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Corals are themselves not coral reefs—the term refers to the tiny marine invertebrates that build the rigid reef.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Most of the observable universe's volume consists of voids and supervoids—enormous regions of space with little to no galaxies, stars, or light.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

In 1963, a basement renovation in Turkey revealed a passageway to a hidden, multilevel underground city that once housed as many as 20,000 people

Some researchers have labeled nomophobia, the fear of being without your phone, as 'the phobia of the 21st century.'

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.