Read more about the backstory on the 2025 Nobel Prize for immune system work

How Nobel Prize-winning research unraveled why the immune system doesn't always attack itself

The 2025 Nobel Prize was awarded to scientists who discovered how immune system soldiers are typically stopped from attacking healthy tissue. The work furthered autoimmune understanding and cancer therapies.

Despite the rules, a Nobel Prize in medicine has been awarded posthumously

Ralph Steinman, whose work revealed how dendritic cells activate immune responses, passed away just days before being named a Nobel laureate. Although Nobel Prizes cannot be awarded posthumously, the committee made an exception because they believed he was alive at the time of the decision.

Explore a list of Nobel Prize winners supported by National Science Foundation grants

As of 2025, 274 Nobel laureates have received funding from the NSF at some point during their careers, including 49 in physiology or medicine, 82 in physics, and 70 in chemistry. The 73 NSF-funded laureates in economics include every prize winner since 1997.

Penicillin’s pioneers were awarded the Nobel Prize in 1945

Alexander Fleming, Howard Florey, and Ernst Chain received the 1945 Nobel Prize in Physiology or Medicine for discovering and developing penicillin.

Only allowing three recipients causes the Nobel Prize to overlook team discoveries

While science has grown more inclusive and collaborative, the Nobel Prize system still struggles with outdated practices, such as secrecy and a rigid limit on awardees. This restriction sidelines many deserving scientists, especially in complex projects like the human genome or gravitational waves.

The Nobel Prizes honor global achievements in science, literature, and peace efforts

Established by Alfred Nobel’s will, the Nobel Prizes have been awarded since 1901 to individuals and organizations making major contributions to humanity. Although often grouped with the five original prizes, the economics award was added later by Sweden’s central bank in 1968 and isn't technically a Nobel Prize.

The 2017 Nobel Prize in physics was awarded to LIGO's founders

Rainer Weiss, Kip Thorne, and Barry Barish won the award for their contributions to the detector a year after the discovery of gravitational waves was announced. Acknowledging the Nobel statutes limited the prize to no more than three people, Thorne stated, "our marvelous discovery is the work of more than a thousand."

The discovery of insulin led to a controversial Nobel Prize in 1923

For centuries, Type 1 diabetes was fatal. The 1920s "discovery" of insulin netted two of its creators—Frederick Banting and his boss, John Macleod—a Nobel prize. Separately, the German doctor Georg Zuelzer synthesized an effective version of the life-saving drug years earlier but was interrupted by World War I.

In 2017, researchers won a Nobel Prize for their work controlling fruit fly circadian rhythms

This detailed circadian rhythm infographic breaks down a day in the biological life of a fly, providing a peek at some of the groundbreaking work that elicited a Nobel Prize in Physiology or Medicine.

Rosalind Franklin’s work led to Nobel Prize-winning discoveries in DNA and virology

Her X-ray diffraction imaging helped uncover the structure of DNA, which earned James Watson, Francis Crick, and Maurice Wilkins a Nobel Prize. The same techniques enabled virus imaging, contributing to Aaron Klug's Nobel Prize in chemistry.

Robert Koch won the Nobel for his tuberculosis work, but he also pioneered cholera research

Koch was one of the first scientists to isolate the bacterium that causes cholera while investigating an outbreak in Egypt in 1883. He went on to advise about rules to control cholera outbreaks, which formed the basis of the disease control approaches and water hygiene techniques still used today.

The Ig Nobel Prizes honor scientific achievements that make people laugh, then think

These prizes show that even seemingly trivial work can gain attention, build momentum, and connect with broader audiences when presented engagingly. Winners include creating a toilet that analyzes your poop and understanding why scientists lick rocks.

The best photos of scientists at work in 2025

The winners of Nature's 2025 photo competition capture the essence of scientific fieldwork in diverse and challenging environments. From a biologist battling waves for whale research to ice core drilling in polar night conditions, this gallery details the research being each winning photo.

Drs. Jennifer Doudna and Emmanuelle Charpentier discuss CRISPR

Jennifer Doudna and Emmanuelle Charpentier's were awarded the 2020 Nobel Prize for research focused on understanding and adapting the CRISPR-Cas9 system to precisely edit DNA sequences in other organisms. Doudna has indicated that the system can potentially treat genetic forms of blindness and high cholesterol.

Marie Curie's research in radioactivity made her the first woman to win a Nobel Prize

Overcoming social and academic barriers, Curie's realization that radiation resulted from an intrinsic property of atoms reframed scientific understanding of the phenomenon. Her subsequent work in discovering two new elements—polonium and radium—earned her a second Nobel Prize.

How the 1918 pandemic spurred developments in virology and vaccines

This article provides an in-depth historical account of the 1918 Spanish Flu pandemic, including its impact on the global population and how its occurrence spurred significant advancements in the study of viruses—laying the groundwork for the...

The 2019 Nobel Prize in Chemistry was awarded for lithium-ion battery development

Stanley Whittingham developed the first functional lithium battery in the early 1970s, while John Goodenough doubled its electrical potential in 1980 by replacing the cathode, thereby enhancing its commercial viability. Five years later, Akira Yoshino developed an anode using carbon material, reducing the risk of flammability.

'Our greatest responsibility is to be good ancestors.'

- Polio vaccine developer Jonas Salk (1914–1995)

The scandal that rocked stem cell research

In 2014, a Japanese research group published a paper suggesting ordinary cells could be reverted to pluripotent stem cells by subjecting them to external stressors. The results generated interest but could never be replicated. The lead researcher was accused of fraud, and the group’s supervisor committed suicide.

Scientists from the frontline discuss the future of antibiotics and superbugs

Superbugs are a very real problem, but researchers around the world are working to advance our understanding of these pathogens and develop new medicines. This podcast talks with several scientists on the frontier of superbug research, offering insight into what we know—and what the future of medicine may look like.

Rune Elmqvist forwent practicing medicine to invent the first inkjet printer

The Mingograph recorded real-time physiological signals from a patient's electrocardiogram, helping doctors diagnose heart and brain conditions. Eight years later, in 1958, Elmqvist worked with cardiac surgeon Åke Senning to develop the first fully implantable pacemaker.

Read why one man agreed to get a pig kidney in 2025 to replace his own failing organ

The 68-year-old New Hampshire man told USA Today that a motivator for the experimental surgery was his belief that he was going to die anyway, and other people suffering from kidney disease could gain valuable insights. Yet the surgery bought him time—he lived 271 days with a pig organ and later received a human kidney transplant. Clinical trials began in 2026 to test the pig xenotransplants in more people.

Visualizing 100 years of Pulitzers

This fascinating data visualization breaks down a century of Pulitzer Prizes. Award categories are laid out against a timeline, and the symbols used to represent each winner indicate the topic of the winning work; the number of prizes won by that outlet thus far; and whether the prize was awarded to an individual or a newsroom. For the best viewing experience, zoom in using the magnifying glass on the cursor until it hits full-screen mode.

The basics behind mRNA vaccines

In this video, Yale experts Saad Omer, MBBS, MPH, PhD; Onyema Ogbuagu, MBBCh; and Akiko Iwasaki, PhD, explain the science behind COVID-19 mRNA vaccines.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Go inside the global effort that led to the Montreal Protocol in this narrative podcast

Nobel laureate Mario Molina and other key voices recount how science and diplomacy converged to develop a plan to close the ozone hole, offering insight into history's most successful environmental treaty.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

See the evolution of Ebola vaccine and treatment development.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Tattoos remain visible on your skin thanks to immune cells called macrophages

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

In preparation for this weekend's Eurovision finale, which is something like the World Cup of pop music, here's a young Céline Dion performing (for Switzerland?) at the 1988 competition.

See the most iconic photos from four decades of LIFE magazine

Double world record holder Hunter Ewen helped conquer his fear of balloons, called globophobia, by training to win Guinness World Record titles for balloon inflation.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

In 1945, Surrealist artist Salvador Dalí and legendary animator Walt Disney began collaborating on a short film that was not completed until 2003, years after both men had died.

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted, leading authorities to suspect he was conspiring with the Russians.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

Track the location of the Voyager probes, currently between 13 and 15 billion miles away from Earth.

The Nasdaq's 'Magnificent 7' companies are responsible for roughly 40% of the Nasdaq 100 index's gains, while the remaining 93 companies account for the other 60%.

Up to a million Girl Scouts sell about 200 million cookie boxes every spring, generating $800 million, largely because refusing a child is frowned upon