In 2017, researchers won a Nobel Prize for their work controlling fruit fly circadian rhythms

Sleep deprivation leads to buildup of danger molecules in the gut

Fruit flies genetically engineered to be awake for as long as they live tend to live half as long as their well-rested brethren. Analysis shows these modified flies suffer from a buildup of DNA-destroying reactive oxygen species in their guts. When enabled to sleep, the flies live as long as their counterparts.

Chronobiologists study the effect of time on biological cycles

Circadian rhythms were first observed in the 1700s, when French astronomer Jean-Jacques D'Ortous de Mairan put a plant in a dark room and watched it still respond to day and night cycles, setting off further studies about specific light-dark biological cycles, an area of inquiry that continues today with the human "clock proteins" at the molecular level.

Parasites have circadian rhythms, too

Researchers are working to unravel how circadian rhythms of parasites and their hosts affect one another. They’re investigating how to potentially target and disrupt those clocks for disease treatments.

Fruit fly experiments show personality emerges, in part, from genetic factors

A 2025 study revealed that fruit flies exhibit unique behavioral preferences, akin to personalities, which could be artificially selected for when breeding to modify behavioral variability. This variability can be adaptive in unpredictable environments.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Read more about the backstory on the 2025 Nobel Prize for immune system work

A trio of scientists won the Nobel in Physiology or Medicine that year, but they performed their award-worthy work beginning about two decades before winning the prize. This announcement includes details about the science and notes that the three scientists will equally share the 11 million Swedish kronor (almost $1.2M).

See a timeline of landmark discoveries in the field of genetics

From the first genetic map of fruit fly genes in 1911 through the completion of the Human Genome Project in 2003, scientists have built upon each other's discoveries to further our knowledge of the human body and the genetic instructions that inform our traits and disease risks.

The body's master clock has 20,000 neurons

The suprachiasmatic nucleus, the master clock in mammals, has 20,000 neurons that help maintain the light-dark cycle in the body. Among its jobs: It receives light input information from the retina and then signals peripheral body clocks to act on this information, driving everything from body temperature to hunger.

Model organisms like yeast, mice, and flies help scientists decode the human body

Some species are used to quickly study the effects of human diseases and treatments because they are short-lived and have similar systems to those found in humans. Bacteria, like E. coli, have been used as human proxies given their rapid growth and ease of genetic manipulability.

What happens when we sleep

Sleep is a highly specialized and complex process that begins via signals from a region of the brain called the hypothalamus. As explained in this overview video from The Economist, the hypothalamus maintains our circadian rhythm by using light cues from our environment to regulate sleep via a compound known as melatonin. Once asleep, the brain begins the "sleep cycle" and progresses through the four stages of sleep over and over again each night.

View the fluorescently stained internal structures of a tardigrade

The photograph won the Olympus Global Life Science Light Microscopy Americas regional award in 2019. Using chemicals from biofluorescent organisms, the image illuminates internal structures with multiple hues in an otherwise mostly colorless organism.

Neural rhythms shape how we move, focus, remember, and interact with the world

Millions of neurons in the brain produce rhythmic electrical signals, or brain waves, that guide physical movement and help form and store memories. Researchers also use these rhythms to create brain-computer interfaces, letting people control devices using only their thoughts.

Examining the potential of the emerging field of insect-based bioremediation

Also known as entomoremediation, the novel approach uses larvae and adult insects, including their gut microbiomes and associated enzymes, to extract or degrade pollutants. As of 2025, research has shown that black soldier flies can degrade a wide range of antibiotics, highlighting their potential for bioremediating antibiotic-contaminated organic waste.

Explore an animated list of nine scientific breakthroughs funded by NASA, the NSF, and the NIH

Among the technologies made possible by the National Science Foundation and the National Institutes of Health were the CAPTCHA digital puzzles to block bots from accessing sites, the set of diabetes and obesity drugs that fall under the umbrella of GLP-1 receptor agonists, and various cordless appliances, including the handheld vacuum cleaner. (Some readers may experience a paywall.)

How the heart achieves its first beat

Scientists observed zebrafish embryos as they grew and isolated the several-second-long initial heartbeats to better understand this crucial moment in every heart's life. The zebrafish's heart starts beating 20 hours into their existence. Each heart cell activates electrically at random, without rhythm. As these cells mature, they become more sensitive to electrical charges; as they all fire, a rhythm is established and a pulse is born.

Learn about the basic anatomy of mosquitoes

This short explainer video breaks down the mosquito's general body components, highlighting how mosquitoes breathe, fly, and more. It also touches on how experts can tell different mosquito species apart.

A day in the life of a leafcutter ant

Among the fascinating world of insects, leafcutter ants form some of the most complex and dynamic social ecosystems. All part of an effort to keep a colony alive, worker ants toil tirelessly, dragging bits of leaves and vegetation back to their...

CRISPR-Cas9 enables precise genome editing using a simple RNA-guided system

Jennifer Doudna's research uncovered how bacteria use the tool as an immune defense by cutting viral DNA. She and Emmanuelle Charpentier received the 2020 Nobel Prize in chemistry for showing how this mechanism could be engineered to target and edit genes in living cells.

The science of symmetry | The Royal Society

Nature is full of symmetries, from spiral galaxies to florets of broccoli. So why do complex creatures break the pattern?This short video discusses why symmetry came to dominate life on Earth, and how many complex life forms, such as humans, transitioned from radial to lateral symmetry.

The scientist that biohacked a buff frog

If a tree frog was injected with a DNA mixture containing follistatin, a gene that may influence muscle growth, would it become buff? Josiah Zayner hopes so. By learning how to biohack animals, he hopes people are one step closer to feeling more comfortable "whipping up DIY gene therapy."

What rodent cars can tell us about human joy

Neuroscientist Kelly Lambert and her colleagues taught rats to drive in a mini car. She writes her findings from this unconventional experiment, sharing that positive and fun experiences can sculpt the brain just as powerfully as stressful ones. Click to learn more about how the apparent joy of these rodents seemed to enhance their neuroplasticity.

How a scientist discovered West Nile is spread by birds

Listen to Tracey McNamara, former chief pathologist at the Bronx Zoo, detailing her surprising late 1990s discovery that established West Nile virus is spread by birds. Financing animal disease surveillance studies, she says, saves human lives and surveillance gaps may fuel missed opportunities to identify dangerous diseases before they jump between species.

Dragonfly migration season is believed to run from August to November

Researchers know much less about dragonfly migrations than they do about bird or whale migrations. However, North America may have up to 18 migratory dragonfly species. A recent study revealed that the species undertakes complex long-distance migrations every year that span generations and seem to be influenced by temperature, making them particularly vulnerable to climate change.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

The inner life of a cell

White blood cells are responsible for protecting the human body from infection. This video uses biophysical data from Harvard researchers to accurately demonstrate what goes on inside one white blood cell as it works within the immune system.

Bees are more likely to remember a flower if its nectar contains caffeine

Plants want pollinators to keep coming back, so the finding suggests that some plants, such as Citrus and Coffea species, have evolved to include caffeine in their nectar. Researchers suggest the findings could help develop methods to reinvigorate pollinator populations.

Apple's latest invention

Apple may be working on a robotic smart lamp. Internally called ELEGNT, it's designed to respond to music, display emotion through movement, and even serve up reminders. A new research paper details how it could work—though Apple hasn't officially confirmed a release.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Scientists have struggled to pin down Ebola's natural reservoir species for decades, but the available evidence suggests that it's very likely fruit and insect-eating bats found in Africa.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

How Amazon operates a 'flywheel' business model, a self-reinforcing cycle that drives continuous growth

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Fear or disgust related to clusters of holes and cracks, called trypophobia, may stem from evolutionary processes to help us avoid pathogens.

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.

In 1945, Surrealist artist Salvador Dalí and legendary animator Walt Disney began collaborating on a short film that was not completed until 2003, years after both men had died.

Learn how to read a prospectus, the juicy document that any company must file with the SEC before going public.

'Saturday Night Fever,' the 1977 film that introduced disco to the mainstream, was based on a fabricated magazine story.

Exploring the Larry Bird punch that almost changed March Madness

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.