Hippocratic doctors treated severe mental illness with the poisonous plant hellebore

'Melancholia' was the ancient Greek term for depression

"Melancholia" in Hippocrates's time was derived from the Greek word for black bile. This term made sense in its context since the Greeks believed that depression stemmed from an improper balance of the four humors.

Pooping or puking out pathogens is sometimes recommended with food poisoning

Sometimes stopping food poisoning-linked diarrhea with over-the-counter medications is a bad idea because it may prolong illness. Doctors can advise you if your diarrhea or vomiting is severe about what medications to take and when, but generally doctors recommend trying to stay hydrated during a bout of food poisoning and letting the body naturally remove pathogens from the body via vomiting or diarrhea, as needed.

Historians theorize Vincent Van Gogh suffered from Ménière's disease or epilepsy

A century after researchers suggested he suffered from epilepsy, some researchers in the 1990s began to support an alternate diagnosis: Ménière's disease, since he had suffered from severe, repeated attacks of disabling vertigo. Still, some researchers remain skeptical of the Ménière's diagnosis. One posits that Van Gogh had temporal epilepsy complicated by his absinthe consumption.

Veterans reported single dose of ibogaine improved TBI, PTSD, anxiety, and depression

Research published in 2024 on the Central African plant-derived drug included 30 male combat vets who received ibogaine treatment in Mexico. It reported significant reductions in multiple mental health conditions and no serious side effects. Other work, however, has shown the substance can cause fatal cardiac arrhythmias, killing at least 19 people between 1990 and 2008. (Some users may encounter a paywall.)

Why might someone want to stay in psychosis?

Author Abigail Gosselin writes that her verbal auditory hallucination, often assumed by others to be harmful or threatening in nature, offered a salve to loneliness, even as it told her to kill herself. This perceived benefit and others Gosselin shares offer insight into why people in psychosis may struggle to adhere to treatment and medication plans.

Cholera was called the 'Blue Death'

In the mid-1800s—when John Snow identified cholera in London—the disease was known simply as the "Blue Death." That's because blood would thicken in patients' veins when they were struggling with extreme dehydration. As a result, their skin would turn a blueish hue as their blood was starved of oxygen.

In 1865, Hawaii's king authorized forcible removal, quarantining of those with leprosy

King Kamehameha V authorized the removal of anyone with leprosy symptoms and for them to be placed in a medical facility later maintained by the Catholic Church on Moloka'i, Hawaii's fifth largest island. Patients weren't allowed to transfer to other medical facilities until 1969.

Ancient Egyptian papyrus from 16th century BCE seems to reference tinnitus

Ancient Egyptians wrote that they treated "bewitched ear" with herbal concoctions that involved frankincense and other ingredients, which were placed in the ear.

How fecal transplants work

1,700 years ago, Chinese alchemist Ge Hong was renowned for his soup that could cure diarrhea-stricken patients. It had a surprising secret ingredient: feces. While it might seem unwise to consume feces, exciting new research suggests that taking...

Learn how Hollywood tries to get mental health portrayals right

"Entertainment is always the first priority," the director of medical research for "Grey's Anatomy" and "Private Practice" explained in this Newsweek article. But, medical consultants and dedicated groups like the University of Southern California's Hollywood, Health, and Society program, can help inform shows' characters, actions, and sensitivities on subjects like mental illness.

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted and led to authorities' suspicions he was conspiring with the Russians

The 1794 incident involved André-Ignace-Joseph Dufresnoy, a French army physician researching the plants' potential medicinal properties. Rhus radicans is a scientific name for the plant, though it's commonly called Toxicodendron radicans.

Mental health symptoms may manifest differently across cultures

Mental health, like physical health, is imbued with values, beliefs, and traditions. Symptoms of distress are not universal and may differ based on racial, ethnic, and cultural contexts. Because mental health may be stigmatized or communities may have varying belief systems about causes of mental health challenges and how to fix them, it may affect how symptoms manifest. Chest pain, for example, may be a sign of mental distress—not the need for a doctor.

A list of five scientific theories that were accepted and later disproved

Humoral theory held that everyone's personality derived from different combinations of four bodily fluids: blood, phlegm, yellow bile, and black bile. The phlogiston theory stated that all combustible materials possessed a fire element—phlogiston—that was released and absorbed by the air during burning. When the air became saturated with phlogiston, the fire would go out.

The medical profession has a dark history of 'body snatching' for education

This term originally referred to secretly removing corpses from graves for sale—usually to medical schools where they were used for education. The practice dates back at least to the 1300s but still—much more rarely—persists today.

'Brave New World' author Aldous Huxley turned to LSD on his deathbed

As "Brave New World" author Aldous Huxley lay dying of cancer in 1963, he asked his wife Laura to dose him with the hallucinogen LSD. A month later, Laura Huxley wrote a letter detailing the author's final trip, which she notes ended "so slowly, so gently, like a piece of music just finishing in a sempre piu piano dolcemente."

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted, leading authorities to suspect he was conspiring with the Russians.

A family's yearslong poisoning

Over 14 years, a southern Indian family slowly lost six members, several of whom were found foaming at their mouths. Upon the third death, a post-mortem examination was requested, revealing cyanide had been ingested, though it was ruled as self-inflicted. Several will edits and three deaths later, relatives turned a critical eye toward Joliyamma "Jolly" Joseph, who had married into the family and been present at each death.

Steve Jobs tried to treat his cancer with alternative medicine

After Steve Jobs was diagnosed with pancreatic cancer, he reportedly restricted his diet to just fruits or just fruits and vegetables, tried out hydrotherapy, and consulted psychics. There’s compelling evidence about the impact of alternative medicine on cancer patients.

What exactly are hiccups?

If you don’t know a surefire cure for hiccups, it’s not really a surprise—while there are some known facts about this funny affliction, a surprising amount remains a mystery. Doctors believe that a round of hiccups usually either comes from...

An engineer tracked his moods for decades and helped researchers identify SAD

Civil engineer Herb Kern had bipolar and would record his moods dating back to 1967. He noticed the seasons were a major factor in the increase and severity of his episodes. By reaching out to researchers at the National Institute of Mental Health, Kern became the first human to confirm increased melatonin levels during winter and to receive bright light therapy.

How the placebo effect became mainstream

Contemporary patients and medical students take the placebo effect for granted, as its a standard element in most drug trials. But the concept was only first debated and standardized in the 1950s after a ground-breaking 1955 paper by medical...

Typhoid smells like freshly baked brown bread

Certain ailments are associated with documented scents, including diabetes, Parkinson's disease, and typhoid. The skin of people with yellow fever, for example, can smell like a "butcher shop."

How the environmental diversity of coral reefs provides potential medical treatments for humans

As immobile animals, corals and the organisms that live on them have evolved a suite of chemical compounds to prevent disease and ward off predators they cannot outrun. These include antibiotics, antivirals, and powerful toxins that target the nervous system and are studied for applications involving pain management and neurological treatments.

Revisiting the ornamental hermit craze of the 1700s

One of the more elaborate gardening trends of the 18th century was the placement of a well-designed hermitage within the landscape, a throwback to the more religious antiquity and the Middle Ages. The trend went so far for some that they hired real live hermits, preferably older, bearded, and willing to stay quiet and out of the way. Read about the wild trend here.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Without liver bile, human poop would be a pale silver color

Stomach acid and enzymes break down food into smaller particles, expelling a semi-fluid mass called chyme into the small intestine, where bile is added. As the intestines absorb nutrients and water, the chyme solidifies and changes color.

Menopause hormone therapy infuses the body with estrogen after the body's natural levels drop

The treatments can treat symptoms like hot flashes and vaginal dryness at varying doses. Progestogen, another hormone, is also typically prescribed with estrogen because estrogen alone can thicken the uterus lining, which elevates the risk of developing endometrial cancer.

Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Before writing 'Walden,' transcendentalist Henry David Thoreau nearly burned down his hometown with a campfire that grew out of control.

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

The first horror movie is believed to be George Méliès' 1986 short 'The Haunted Castle,' which pioneered the use of special effects

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.

After the Boston Tea Party, colonists switched to coffee, which became the main morning drink for revolutionaries.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Power lines are dotted with large, brightly colored balls to improve the visibility of these thin wires to helicopters and small planes and help prevent potential crashes.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.