In 1939, baseball star Lou Gehrig delivered his 'Luckiest Man' speech after retiring due to a health condition

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Stephen Hawking's final message

Famous cosmologist Stephen Hawking—who lived for half a century after being diagnosed with Lou Gehrig's disease—delivered a final speech just before he died in 2018. In the video, Hawking talks about the importance of science and reason in...

How ALS (Lou Gehrig’s Disease) might work, and what scientists are learning about it

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that affects the nerve cells (neurons) controlling muscle movement. As the motor neurons degenerate, they stop sending signals to the muscles, causing progressive muscle weakness and, eventually, death. This three-minute animation focuses on the mechanisms within the motor neurons that cause them to degenerate. By understanding these mechanisms, researchers hope to one day find a cure for ALS.

Defying the odds, Stephen Hawking outlived his ALS diagnosis by over 50 years

When diagnosed with ALS, Stephen Hawking was given two years to live. However, he survived with the progressive neurodegenerative disease for over 50 years, highlighting the disease's variability and complexity.

Talese’s story on Joe DiMaggio examined the sports star’s life post-retirement

The profile, written in the aftermath of his popular “Frank Sinatra Has a Cold,” similarly offered a close look at an American icon after their prime. In DiMaggio’s story, however, the Yankees player seeks to vanish into obscurity and live a quiet life, golfing and mourning his ex-wife Marilyn Monroe.

Despite the rules, a Nobel Prize in medicine has been awarded posthumously

Ralph Steinman, whose work revealed how dendritic cells activate immune responses, passed away just days before being named a Nobel laureate. Although Nobel Prizes cannot be awarded posthumously, the committee made an exception because they believed he was alive at the time of the decision.

Some say baseball's drug problem goes back to the late 1800s

At age 32, pitcher James “Pud” Galvin was feeling tired and decided to take "the Brown-Séquard elixir," which contained a testicular fluid from dogs and guinea pigs, believed to invigorate tired bodies. It might've worked: Galvin pitched a two-hit shutout the next day.

After FDR was paralyzed by polio in 1921, Eleanor Roosevelt became active in politics and supported his political ambitions

FDR contracted polio at age 39 and permanently lost the use of his legs. Eleanor Roosevelt persuaded him to stay in politics, then took on the task of maintaining his public profile—attending events, building relationships, and serving as his "eyes, ears, and legs" across the country.

The origin story of the Paralympic movement and its founder, Dr. Ludwig Guttmann

Dr. Ludwig Guttmann, the founder of the Paralympic movement, revolutionized the treatment of spinal injuries. His belief in the power of sports for rehabilitation led to the creation of the Paralympic Games, now celebrated every Olympic year. This in-depth article from The History Press details the life and achievements of Dr. Guttmann, and includes historical photos and videos of the veterans-turned-athletes whose lives he changed.

Camus was a soccer goalie as a teenager

The writer played for Algiers Racing University but had to quit after contracting tuberculosis. He remained a fan, though, once suggesting that the game taught him important lessons about morality. In the 1957 interview below, he briefly reflects on his time as a goalie and speaks about his recent Nobel Prize.

Magic Johnson's announcing he had HIV changed public perception of the disease

When Lakers superstar Magic Johnson announced he had HIV in 1991, the disease was highly misunderstood. Commissioner David Stern had behind-the-scenes conversations with Johnson about publicly handling his eventual announcement, leading to the start of the condition's destigmatization.

In 1999, King survived a near-fatal car accident

In 1999, a distracted driver hit writer Stephen King as he walked on the side of the road near his house in Maine. He recounts the event in his famous memoir, "On Writing." This interview with Katie Couric took place five months after the accident and shows King in a fragile state, wondering about the long-term effects on his mind. When Couric asks if he'll try to work the incident into his work, he smiles. "Sooner or later," he says, "everything goes in."

Robinson is among the league's greatest figures

Robinson won Rookie of the Year and played in the majors for 10 seasons, winning a World Series in 1955. He was inducted into the Hall of Fame in 1962. The Dodgers retired his number, 42, in 1972, and MLB retired it league-wide in 1997.

Buffett is known for being extremely generous with his fortune

So generous that in 2010 he pledged to donate 99% of his money. He said this money “can have a huge effect on the health and welfare of others.” This letter is Buffett’s philanthropic pledge, which details his commitment to giving and how luck and privilege helped him accumulate so much money.

After a dementia diagnosis, it's important to plan ahead but also savor the moment

The next steps after a diagnosis include taking lifestyle steps to slow disease progression and completing legal paperwork about long-term medical preferences. It's also important to appreciate the moments and days ahead and find humor in them, when possible. (Some users may encounter a paywall.)

CTE is a major threat to NFL players

A week before Super Bowl LVII, Boston University released findings from a study diagnosing 91.7% of former NFL players in their 376-person study with chronic traumatic encephalopathy. It was a stark comparison to the less than 1% of CTE diagnosis in non-football players.

Beethoven's correspondence in 1801 documented his tinnitus suffering

Ludwig van Beethoven's hearing loss is one of the best-known cases of this condition among historical artists. He also suffered from tinnitus and wrote in 1801, "My ears are buzzing and ringing perpetually, day and night. I can with truth say that my life is very wretched…"

Eugene O'Neill is the lone American playwright to win the Nobel Prize

The writer was awarded the Nobel Prize for literature in 1936, with the prize committee noting "the power, honesty, and deep-felt emotions of his dramatic works, which embody an original concept of tragedy."

Six-year-old boy in wheelchair surprises his family by walking at his graduation

The young boy was diagnosed with Noonan syndrome, a rare genetic disorder that impacts mobility and development, at just 2 months old. He usually needs a wheelchair or walker to get around, but he shocked and thrilled his parents by standing up to receive his kindergarten diploma.

Searching for Albert Einstein's stolen brain

Within moments of Einstein's 1955 death, someone reportedly ferreted away the 76-year-old genius's brain. Decades later, a reporter's editor told them to solve the case. This 64-minute podcast episode follows the work of Steven Levy, the reporter who ultimately tracked down Einstein's brain, which had been sliced and stored in slides, goo, and a cardboard box in a scientist's office.

Famed American investor Jesse Livermore made millions when the stock market crashed in 1929

Livermore made his first major short against rail company Union Pacific in 1906, coincidentally before an earthquake in San Francisco, which ultimately tanked share prices. During a financial panic the next year, JP Morgan reportedly asked Livermore to increase his long-term investments to restore hope and restabilize the market—which Livermore did. However, Livermore began betting against the market in 1929, sensing that stocks were too hot, and was one of the few people to benefit from the 1929 stock crash.

Read an account of what life was like in America's national leprosarium—its leper colony

José Ramirez Jr. shares an account of his eight years at the 300-acre national leprosarium in Carville, Louisiana, from 1968 through the mid-1970s. Mostly staffed by nuns with nursing degrees, this facility was home to hundreds of people at a time, and it's also the site where they were required to be buried.

Langston Hughes solicited ghost stories from his readers

Hughes had a column in the Chicago Defender newspaper for two decades. In 1951, he asked readers to send him their ghost stories, promising that he'd reward them with autographed copies of his books. He spent the next several months dedicating the column to the stories he received.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

A tragic injury led to the original NHL All-Star Game

The annual NHL All-Star Game is a joyous affair celebrating the best players each season. But its origins came from one of the most terrifying moments in hockey history. In a 1933 game, Maple Leafs wing Ace Bailey was nearly killed on the ice, and the NHL organized a benefit game to raise money for his family.

'Let us learn to show our friendship for a man when he is alive and not after he is dead.'

Meyer Wolfsheim in F. Scott Fitzgerald's "The Great Gatsby"

America's top causes of death are heart disease, cancer, accidents, and stroke

Heart disease killed more than 680,000 people in 2023 and cancer killed around 613,000 people that year. Both causes of death are far above the next leading cause of death—accidents, which numbered around 223,000. Provisional data for 2024 indicates the leading causes of death remained the same.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Exploring the Larry Bird punch that almost changed March Madness

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Mark Twain spent decades feuding with the US Postal Service, convinced its costs and regulations were bureaucratic overreach.

A researcher recently discovered an interview from 1967 between groundbreaking journalist Joan Didion and the Grateful Dead, years before the band became an institution.

American dance legend Martha Graham, sometimes called 'the Picasso of dance,' refused to perform at the 1936 Olympics in Berlin and conceived the piece 'Chronicle' in response to the experience.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

Warren Buffett's former professor Benjamin Graham is known as the 'father of value investing,' a strategy in which investors seek to buy stocks trading below their intrinsic worth.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

Double world record holder Hunter Ewen helped conquer his fear of balloons, called globophobia, by training to win Guinness World Record titles for balloon inflation.

The tragic Pulitzer Prize-winning image 'The Vulture and the Little Girl' (1993) generated controversy, raised concerns about ethics in photography, and eventually led to the photographer's death.

The 1987 Nintendo video game 'Stadium Events' isn't known for being particularly fun, but its scarcity has made it a highly sought-after item that has sold for up to $35K at auction.

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

Domino's Pizza's 30-minute delivery guarantee was responsible for the chain's 1980s surge, but it was discontinued after the company was found liable for delivery driver accidents.

Neutron stars, the remains of some massive stars after they explode in a supernova, are the densest directly observable objects in the universe.

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.