Coffee gives you energy, but it ultimately makes you more tired

Coffee is, indeed, addictive

Caffeine enters the brain through the bloodstream, where it blocks receptors that cause us to feel tired and enables stimulants like dopamine to increase alertness and focus. Over time, the brain begins to expect this level of stimulation, and caffeine addiction can develop. Caffeine withdrawal causes headaches, irritability, and fatigue.

Coffee is, generally, good for your health

While overconsumption certainly has its drawbacks—hello, not sleeping until the sun rises—on the whole, coffee is fine, even beneficial, for your health. It can even help prevent serious health conditions, like heart attacks and liver cancer.

Coffee contains an average of 15mg of caffeine per fluid ounce

Coffee has three times the amount of caffeine contained in most caffeinated sodas, but significantly less than espresso and cocoa powder.

A caffeine calculator

This simple calculator takes your preferred caffeinated drink and your body weight to determine how much is the right amount, and how much might kill you. In case you've ever had the morbid curiosity about just how much of that tea you'd have to drink to doze off forever. Find out your moderate and lethal doses here, as well as some extra info on caffeine consumption.

The brain will attempt to rest itself in periods of chronic sleep deprivation

Skimping on sleep lengthens reaction times and blunts decision-making skills. At a certain point, the brain will try to sneak sleep where it can, shifting sections offline even as you remain awake. Going without sleep raises blood pressure, undermines the immune system, and increases one's risk of dementia.

Muscles fatigue due to the loss of energy like ATP and glycogen

Adenosine triphosphate fuels muscle contraction, and with each contraction (like during exercise), the amount of ATP reduces. ATP helps potassium and sodium move across muscle membranes, generating ions and helping to contract the muscle.

The benefits of power napping

Research shows it may not be beneficial to fight that mid-afternoon drowsiness: Power naps can make you more alert, reduce stress, and improve your cognitive function.

Your DNA may determine whether you like coffee or tea

Whether people prefer coffee or tea may boil down to a matter of taste genetics. People with a version of a gene that increases sensitivity to the bitter flavor of caffeine tend to be coffee drinkers, according to a report. Read on for more.

Up to 400 milligrams of caffeine a day is considered safe

Small, frequent doses can be more effective than large amounts, though caffeine can raise blood pressure and heart rate, especially in people with hypertension. While low doses of caffeine may help with depression by stimulating dopamine, excessive caffeine, particularly from energy drinks, can lead to anxiety and heart issues.

Bees are more likely to remember a flower if its nectar contains caffeine

Plants want pollinators to keep coming back, so the finding suggests that some plants, such as Citrus and Coffea species, have evolved to include caffeine in their nectar. Researchers suggest the findings could help develop methods to reinvigorate pollinator populations.

Understanding the distinctions between coffee types

If you’ve ever felt overwhelmed looking at a coffee shop menu, you're not alone. Here's a breakdown between common coffee styles. Click through the link to see similar guides to espresso and cold drinks.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Coffee is made by brewing the seeds from the coffeea plant

The cherries from the coffeea plant are milled into coffee beans. After processing, the beans are dried and roasted.

Beanless 'coffee' is an eco-friendly alternative

As we consider the role of agriculture in climate change, many people are seeking alternatives to the most resource-hungry crops—coffee included. Are new synthetic alternatives the answer? Startups are exploring beanless “coffee” made in a variety of ways.

How alcohol rewires your brain

Alcohol doesn't just make you tipsy—it rewires your brain chemistry in real time. It slows your brain with GABA, spikes dopamine to make you feel unstoppable, and blocks glutamate so you can't form memories. That mix explains everything from slurred speech to blackouts … and brutal hangovers.

The depression paradox refers to a lack of energy to take action to help alleviate it

Activities like exercise, even at low levels, have been shown to alleviate some of depression's symptoms for some people. However, depression saps energy levels, making it particularly difficult to motivate oneself to take helpful action.

People are experiencing AI 'brain fry' at work

Workers, particularly in marketing, are experiencing mental fatigue in the workplace due to expectations—often unspoken—that they should use AI to multitask beyond their comfort levels. Many feel they are underperforming if they don't embrace this technology. This situation differs from typical burnout. This podcast discussion suggests that this "brain fry" tends to intensify when employees are required to use more than three AI tools.

The myth of sugar rushes vs. the reality of sugar crashes

It's generally accepted that sugar rushes are a myth, and that hyperactivity is a more psychological experience. However, there is real science behind the rare sugar crash that primarily impacts those with diabetes. Read this article to understand how historical and cultural factors have shaped sugar perceptions, and how low blood sugar can trigger shakiness, fatigue, weakness, and more in diabetes patients.

Before it was a drink, coffee was used for handwashing

Five centuries before the caffeinated drink was consumed, coffee beans were used for their aromatic quality. One 10th-century text explains how it "obliterates greasy smells of food on hands and whatever of sweets and fats. Whether traveling or at home, neglect not to wash your hands with it."

Key symptoms of burnout can be both mental and physical

Burnout can be accompanied by several symptoms, including low energy and chronic fatigue, trouble concentrating, difficulty sleeping, and depression. It may even manifest physically as musculoskeletal pain, headaches, stomach and intestinal pain, and more. More intense cases have been linked to cardiovascular and mental health disorders.

Exercise releases chemicals that enhance cognitive function

Neurotransmitters like dopamine, serotonin, and norepinephrine, along with increased brain-derived neurotrophic factor levels, enhance a wide range of brain functions. New research demonstrates a direct link between movement and numerous cognitive benefits, including memory, learning, and stress resilience.

After the Boston Tea Party, colonists switched to coffee, which became the main morning drink for revolutionaries.

The stages of fasting

What happens to the body when it goes without caloric intake? This article overviews the immediate physical effects of fasting. Within a day of going without food, the body will have used up its glucose stores and ordered the liver and muscles to convert their glycogen (glucose storage) into usable glucose. By the second day, glycogen stores will run out, forcing the body to use fat as energy. This process is known as ketosis.

Can we speed up our metabolisms?

Listen to this 31-minute podcast to better understand what science knows and doesn't know about metabolism, as well as the only thing that seems capable of changing it. Scientists understand that the difference between a so-called “fast” and “slow” metabolism does not affect one’s ability to lose weight.

Stress-induced hormones contribute to gray hair

When the body experiences stress, the sympathetic nervous system releases the hormone norepinephrine. This hormone prematurely activates pigment-producing cells (melanocytes) in hair follicles, which depletes the hair's ability to retain color over the long run.

How does cancer actually kill someone?

While the emotional and physical tolls of cancer are often clear, the innerworkings of how cancer kills can be confusing — and terrifying to discuss. Here, oncologists explain how cancer can progress.

Opioids mimic naturally produced endorphins to dull pain

Once in the body, opioids bind to naturally occurring opioid receptors typically used by endorphins to temper pain. They trigger the release of dopamine, a desire-related hormone, and decrease noradrenaline, a neurotransmitter involved in heart and breathing rate regulation, meaning high doses can slow these processes to dangerous levels.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Some renewable energy sources may weaken the resiliency of electric grids by removing outage buffers provided by coal- and natural gas-fired plants, which provide the system with more time to find a new power source if a plant goes down.

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

When you complete a CAPTCHA on a website to prove you are human, you may be unknowingly training algorithms for self-driving cars, whose systems require training data to help identify crosswalks, bicycles, and other outdoor objects.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

The word 'jazz' evolved from 'jasm,' 19th-century American slang for 'energy'

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

The price of gas is a composite made up of several different factors, with the federal gas tax making up less than 20% of what drivers pay at the pump.

US consumers collectively owe more than $1T to credit card companies—almost as much as they owe in auto loans.

While the sun's gravity keeps the planets in orbit, their gravity also pulls on the sun, causing it and everything else in the solar system to orbit around a mutual balance point called the barycenter—the true center of the solar system.

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

Use this tool to calculate the dollar value of your parental mental load, from meal planning to coordinating after-school care, then see resources that help generate solutions.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

See a ranking of the best (and worst) Federal Reserve Chairs since 1914 out of the 16 men and women who have held the office since.

Apollo astronauts left items in the moon's 'toss zone,' including golf balls, family photos, and bags of human waste, to make room for lunar rocks.