Narcolepsy occurs when the brain loses its ability to control its sleep-wake cycle

Sleep paralysis occurs when the body fails to 'unfreeze' in sync with waking

When the body falls into a deep enough phase of sleep, it paralyzes certain parts of itself so the brain can't force it to physically act out dreams. This well-known but little-understood phenomenon happens when the brain awakens early and typically results in haunting hallucinations and reports of supernatural terrors.

Gibberish, urine, and utter chaos: what happens when you sleepwalk

Sleepwalking, or somnambulism, occurs most frequently in children who are in the deepest stages of sleep. REM, the sleep stage in which most people dream, often causes temporary muscle paralysis, so it’s only when sleepers pass to the deeper stages of sleep that sleepwalking—and sleep talking—can occur.

Why do we sometimes jolt awake before falling asleep?

Around 70% of people are estimated to experience the sensation of falling and jerking awake right as they're about to drift to sleep. That mysterious phenomenon is called hypnic jerking. As common as it is, hypnotic jerking remains disconcerting and hard to explain. While we don't yet have clear answers, peruse this article in Popular Science for some possible explanations as to why this happens.

What happens when we sleep

Sleep is a highly specialized and complex process that begins via signals from a region of the brain called the hypothalamus. As explained in this overview video from The Economist, the hypothalamus maintains our circadian rhythm by using light cues from our environment to regulate sleep via a compound known as melatonin. Once asleep, the brain begins the "sleep cycle" and progresses through the four stages of sleep over and over again each night.

Sleep disorders can exacerbate neurological and other health conditions

Brain regions that control sleep sit adjacent to those that regulate the autonomic nervous system, which controls involuntary bodily functions like heart and breathing rates. These neighbors influence each other, meaning poor sleep can impair or negatively impact the ANS, further disturbing sleep.

The neuroscience of REM atonia disorders, where patients act out dreams

What prevents the typical person from acting out their dreams? Temporary paralysis of skeletal muscles, usually leading up to, and during, REM sleep. This academic article and related graphics explore what happens when this process doesn't go as planned, leading to REM sleep behavior disorder.

What it's like to live with insomnia

The biological process Shakespeare referred to as the chief nourisher of life's feast is necessary for the body and mind to rest and repair from the activities of daily life. As sleep evades the exhausted, sufferers also lose emotional stability, mental clarity, social connections, and more while simultaneously gaining waves of interrupted biological processes that can lead to disease and death.

The deadly genetic disease that steals shut-eye

Few are haunted by fatal familial insomnia. This neurodegenerative disease is typically carried through bloodlines via genetic mutation of the prion protein gene, forcing the body to create abnormal and pathological protein variations that can corrupt normal versions. This article follows a musician as they attempt to come to terms with the FFI plaguing their family (and, possibly, their future).

About 10%-15% of people experience chronic insomnia

How often would you say you struggle to stay or fall asleep? If it's more than three times per week (and has been going on for at least one month), then you might have one of the most common sleep disorders: insomnia.

Nightmares are unpredictable, but are linked to stress, anxiety, trauma, and more

Nightmare comes from the terms "night" and "mare," an Old English word for evil, suffocating spirits. Nightmares are parasomnias, meaning they are undesirable events experienced during sleep, and may stem from building tensions in one's unconscious.

What sleep loss does to the brain

Proteins in the brain perform various critical functions, such as helping neurotransmitters function or enabling electrical activity in the organ. These proteins must fold in specific ways to perform their duties, similar to paper airplanes. Sleep deprivation contributes to the gathering of misfolded proteins that aren't shaped correctly for their roles and so accumulate in undesired spaces, such as in the gaps between neurons.

Are you hypnotizable?

What causes some people to genuinely fall under the spell of hypnosis and others not? The technique only appears to work easily on about 10% of people, and a variety of both genetic and psychological factors determines one's susceptibility. Researchers suggest effective hypnosis has more to do with a person's self-control than with external influence—and the technique can have tangible benefits.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

Circadian rhythm disruption can influence various mental health disorders

This 2020 research overview surveys the relationship between disrupted circadian clocks and disorders including schizophrenia, anxiety, and bipolar disorder. It incorporates findings and therapeutic approaches drawing from human night shift studies and jet lag studies alongside animal research.

The hippocampus plays a central role in dreaming

It's theorized that the hippocampus—a brain structure involved with memory formation and the simulation of imagined and novel scenarios using those memories—plays a major role in dreaming. Studies of people with damaged hippocampi show that they still dream, but their dreams lack the richness of detail described by others.

Narcan is an opioid antagonist that can rapidly reverse overdoses

Naloxone, also known by the brand name Narcan, is an opioid-overdose reversal medication that typically begins working within a few minutes. An opioid antagonist, the treatment attaches to opioid receptors without activating them, forcing opioid molecules out of their respective receptors and allowing users' breathing rates to normalize.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

A closer look at why people snore

Snoring is simply noise caused by improper airflow during sleep—and while it’s something that most people will do at some point in their lives, it can also be indicative of larger health problems. Generally speaking, snoring occurs when soft...

Lucid dreaming: the ability to control or influence your dream environment

Every night, most of us dream, but about 20% of people experience lucid dreaming at least once a month. In these rare moments, dreamers are aware they're dreaming, and can even control their actions. Though linked to increased frontal lobe activity, why this state occurs remains a mystery.

How seizures (potentially) alter consciousness

Seizures occur when intense electrical activity floods the brain, prompting significant loss of self-control and a variety of sensory disruptions and hallucinations. Cultures interpret the episodes differently, with many contemporary norms viewing them as negative while others characterize them as intense spiritual occasions. Author Fyodor Dostoyevsky viewed his seizures this way, as well as cultures in Mongolia, some Shamanic indigenous religions, and others.

Schizophrenia symptoms often appear suddenly

Schizophrenia is a particularly shocking mental illness because its symptoms may appear seemingly without any prior signs of illness after a person has had no symptoms for the first couple of decades of their life. Among teens, symptoms may look like typical adolescent behaviors—withdrawal, being irritable, and having trouble sleeping.

The benefits of power napping

Research shows it may not be beneficial to fight that mid-afternoon drowsiness: Power naps can make you more alert, reduce stress, and improve your cognitive function.

When to see a doctor over memory lapses

Memory includes various, distinct functions, like working memory (storing information temporarily) and procedural memory (your body's ability to perform a task unconsciously). Forgetting a word or losing your keys can feel like red flag memory lapses, but they are, in fact, language or attention problems, not memory ones. However, a lapse on top of stress, lack of sleep, chronic dysfunction, or an injury may be a red flag to see your doctor.

AI models incorporate a randomness parameter when generating responses to prompts

AI models use this parameter to prevent repeated outputs by sometimes choosing less likely next words during sequential generation. However, this randomness—alongside insufficient data and training—may cause hallucinations of incorrect results.

Nerve axons become damaged by leprosy, so patients may lose feeling in their skin

Infection of the peripheral nerves—nerves outside the brain and spinal cord—is a known complication of leprosy. That damage can cause patients to lose their sense of touch and the ability to feel pain or temperature in affected areas, leading to accidental injury.

The psychology of narcissism

It's not just an insult: Narcissistic personality disorder impacts thousands of people—and there are ways to get better. Here's a short video explaining it.

Type 1 diabetes is an inherent autoimmune disorder inhibiting insulin production

Diabetes causes the body to attack insulin-producing cells in the pancreas, causing a shortage or lack of insulin. This prevents the body from accessing and storing blood sugar—the brain and muscles' primary energy source. It's unclear what causes Type 1 diabetes, an incurable yet manageable chronic condition as of 2024.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Lesser-known phobias include turophobia, or the fear of cheese, and nomophobia, the fear of being without your cell phone.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Poison ivy's rash-causing compound is found in the plant's roots, stem, and leaves—so coming into contact with any part of the plant can lead to rashes for the 85% of people who are allergic to it.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

11 people died from firework injuries in the US in 2024.

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

See photos of Meteora, a mountainous site in central Greece, home to 14th-century monasteries perched atop soaring outcroppings.

Despite being favored by 87% of Americans, Congress does not have term limits.

Explore the known asteroids, comets, and spacecraft involved in asteroid studies within our solar system with 'Eyes on Asteroids,' a 3D visualization from NASA.