The term 'low T' was coined in 2002, recasting testosterone therapy and elevating demand

Men are flocking to hundreds of new online testosterone clinics for low T prescriptions

Many primary care clinicians may not be familiar with testosterone testing protocols and treatments, but online testosterone clinics are proliferating, with names like DudeMeds. COVID-era restrictions loosened remote prescribing rules, allowing them to expand online widely, though those more lenient prescribing policies are slated to expire in December 2026 unless they're renewed. (Some users may experience a paywall.)

Testosterone prescriptions remain very low overall

Though demand for an injectable formulation of testosterone roughly doubled between 2019 and 2025, testosterone prescriptions still remain very uncommon—adding up to less than 2 per 100,000 prescriptions in 2025.

FDA removed its cardiovascular risk warning on testosterone products in 2025

The change came a decade after the FDA added the label. Recent work, including a gold-standard randomized trial, found that men receiving the products had similar cardiovascular risk levels as men taking placebo products. Testosterone, however, may hold other health risks, including infertility.

Testosterone therapy can cause infertility, and has been explored as a contraceptive

Augmenting testosterone with testosterone hormone therapy suppresses sperm production, and the resulting infertility is permanent in some men. Though a high level of testosterone inside the testicles is essential for fertility, testosterone supplements suppress the production of the pituitary hormones that leads to that natural testosterone production in the testicles—causing infertility.

America doesn't have enough estradiol patches for menopause and perimenopause demand

Fueled in part by the lifting of the FDA's black box warning about HRT risks, sales of estradiol patches in the US have shot upward. More than 142 million units of the patches were sold in 2025 versus 46.5 million in 2020. Suppliers are failing to keep up with demand—11 patch products were in short supply in early 2026. (Some users may experience a paywall.)

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

Overmedication has put type 2 diabetics at risk of low blood sugar

Type 2 diabetics in the US risk dying from low blood sugar, an epidemic traced to a decades-old, multi-million-dollar drug industry campaign encouraging an average blood sugar level below 7%. Contemporary research correlated such levels with reduced risk of eye, nerve, and kidney damage and increased hypoglycemia risk.

How the placebo effect became mainstream

Contemporary patients and medical students take the placebo effect for granted, as its a standard element in most drug trials. But the concept was only first debated and standardized in the 1950s after a ground-breaking 1955 paper by medical...

Peptide TB-500, promoted for regenerative healing, is not FDA approved

Watch a board-certified sports medicine therapist detail his thinking about this synthetic peptide; he says it's "promising but unproven." He notes that this product is designed to mimic the natural protein thymosin beta-4, found in human and animal tissues, which promotes wound healing. TB-500 is classified as a research peptide for recovery, meaning it's not approved for human use and has not yet undergone rigorous human trials on its safety and efficacy.

View the periodic table of radioactive elements, and a list of each's most stable isotopes

Technetium is the lightest artificial radioactive element, which is produced primarily as a byproduct of nuclear fission. Several unstable isotopes are commercially available to medical professionals and scientists, despite their radioactivity risks.

Leonard Thompson was the first human to receive an insulin injection for diabetes

In January 1922, the 14-year-old was the first person to receive an insulin injection to treat diabetes, just months after insulin was isolated in dogs and used to treat their induced diabetes. Thompson had an allergic response to an apparent impurity in the injection, but his second dose, 12 days later, was a success.

While the first exchange-traded fund (a 'basket' of different assets that can be bought and sold on a stock exchange) in the US only launched in 1993, the global ETF market has grown to more than $10T in the short time since.

A new tinnitus therapy involves mild electric tongue shocks and sound exposures

Lenire, an FDA-approved bimodal neuromodulation treatment approach for tinnitus, aims to teach the brain to distract itself from tinnitus. It includes short-term daily sessions wearing a mouth device that delivers mild electrical pulses to the tongue while listening to different sounds. (Some users may experience a paywall.)

'Deinfluencing' explained

You’ve probably heard of influencers, but have you heard of “de-influencers?” Basically, the de-influencing trend started when creators began making videos about products you shouldn’t buy, rather than sponsored content promoting things you should purchase. Comedian Taylor Tomlinson recently cracked some jokes about the trend, and its companion “under consumption-core.”

Magic Johnson's announcing he had HIV changed public perception of the disease

When Lakers superstar Magic Johnson announced he had HIV in 1991, the disease was highly misunderstood. Commissioner David Stern had behind-the-scenes conversations with Johnson about publicly handling his eventual announcement, leading to the start of the condition's destigmatization.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Photodynamic therapy is one current treatment for age-related macular degeneration

This laser-based treatment is used on advanced "wet" age-related macular degeneration patients, but it's now used less often than in the past because there are newer injection-based drugs to decrease abnormal blood vessel growth.

Food companies are exploring 'GLP-1 friendly' diet labels

Producers of foods like Healthy Choice frozen meals are placing "GLP-1 friendly" labels on their food, but there's no regulation about what that label means. Nutritionists say that GLP-1s can help reduce appetite, but healthy, balanced diets are a necessary complement to the medications. Data shows that about half of GLP-1 users quit these medications within a year and then rapidly regain weight, underscoring the importance of also prioritizing healthy eating.

Arnold Schwarzenegger fueled a lot of the interest in strength training, beginning in the 1980s

This was notable because clinicians around the 1950s thought that lifting heavy weights was bad for health, dampening muscle-strengthening interest that dates back to the ancient Greeks. Beyond Schwarzenegger-inspired interest and the popularity of Venice Beach bodies, the weight training movement also later gained momentum due to accumulating scientific evidence and the rise of entities like Crossfit. (Some users may experience a paywall.)

A Bay Area lab was supplying MLB players with steroids

The Bay Area Laboratory Co-operative, also known as BALCO, began as a modest vitamin shop, but by the 1990s it was at the center of a doping scheme that rocked Major League Baseball and other professional sports.

Dove’s ‘Real Beauty’ campaign sparked conversations about beauty standards in media

For the 20-year anniversary of the campaign in 2024, Dove conducted a brand-commissioned study to gauge how perceptions of beauty standards have shifted since its launch. While 81% of US women thought “the media and advertising set an unrealistic standard of beauty that most women can’t ever achieve” in 2004, the share had shrunk to 69% in 2024. Watch the ad here.

US federal law dictates that all ads must not be deceptive

It also dictates that all ads must be “not misleading, and, when appropriate, backed by scientific evidence.” However, enforcing these laws can be difficult given the massive number of ads that run all over America each day. This explainer on the subject from the FTC provides more information.

Average three-month CD rates reached a historical high of 18.65% in December 1980

Comparatively, average three-month CD rates reached a low of 0.09% in June 2021 amid the economic turmoil of the COVID-19 pandemic. When inflation began to rise in 2022, the Fed began initiating rate hikes to incentivize saving.

Trials ongoing for a 99% accurate, AI-powered blood test

The UK's National Health Service has launched a trial for a blood test that can detect a dozen types of cancers with just ten drops of blood. An AI tool looks for genetic material known to be released by tumors, allowing for cancer detection before tumors are large enough to be imaged.

Menopause, once not discussed in polite company, is now a plot point in some television shows

Menopause has long been a topic left out of film and TV. But some shows, like "The Change," and celebrities, like Jennie Garth, are now openly talking about it. This article breaks down how Hollywood is starting to come around to the menopause conversation and how celebrities are talking about their own personal experiences, as well as advocating on Capitol Hill.

The first stablecoin pegged to the US dollar launched in 2014

That coin was Tether, also known as USDT. Other key dates in stablecoin history include Circle's launch of USDC in 2018, and, more recently, President Donald Trump's signing of the GENIUS Act in 2025.

Trader Joe's hired a college student to advise on health food lingo

The grocer jumped into the 1970s health food movement by selling granola, fresh juice, nuts, and raw milk. Joe Coulombe, the company’s founder and namesake, hired “a young hippie woman” from the University of California at Santa Cruz to teach employees the language of the health food movement to properly label their products.

Tesla's production of a high-performance electric vehicle revived the EV industry

The Model 3 shifted public perception by showing that EVs could be fast and desirable, and built at scale. However, at one point, Tesla built an entirely manual production line in a tent outside its main factory to keep up with demand.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

20,000 letters to the advice columnist 'Dear Abby' provide insight into prevailing sex, religion, and LGBTQ fears, anxieties, and concerns from the 1950s onward.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

The distributor behind 'Rocky Horror' pulled the film from its scheduled national release, believing it would be a failure, though it eventually amassed a dedicated fanbase through midnight showings, a trend that continues over 50 years later.

The most expensive ad of all time was for Chanel No. 5 perfume and cost roughly $33M to produce in 2004—about $57M in today's dollars.

Children are now three times more likely to say they want to be a YouTuber when they grow up than an astronaut, with some even attending 'YouTube camps' that teach kids how to create content for the platform.

Jimmy Carter signed a 1978 bill that legalized home brewing, a move credited with kick-starting the craft beer industry.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

The price of gas is a composite made up of several different factors, with the federal gas tax making up less than 20% of what drivers pay at the pump.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

The 1987 Nintendo video game 'Stadium Events' isn't known for being particularly fun, but its scarcity has made it a highly sought-after item that has sold for up to $35K at auction.

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

The identity of the Tank Man in the iconic photo from the 1989 Tiananmen Square protests remains unknown and was possibly killed.