Men are flocking to hundreds of new online testosterone clinics for low T prescriptions

The term 'low T' was coined in 2002, recasting testosterone therapy and elevating demand

The marketing shift and accompanying awareness campaigns, both by the company behind the first testosterone product approved by the FDA, changed the landscape for testosterone product demand. Testosterone is often considered low when it's below 300 nanograms per deciliter of blood. (Some users may experience a paywall.)

Testosterone prescriptions remain very low overall

Though demand for an injectable formulation of testosterone roughly doubled between 2019 and 2025, testosterone prescriptions still remain very uncommon—adding up to less than 2 per 100,000 prescriptions in 2025.

Telehealth demand for GLP-1s is booming as consumers seek easier access

Telehealth companies are rapidly expanding access to GLP-1s, but some doctors and researchers worry that these services are inadequately screening patients, skipping follow-up care, and prescribing cheaper compounded versions with little regulatory oversight—setting the stage for troubling medication errors and serious adverse events.

America doesn't have enough estradiol patches for menopause and perimenopause demand

Fueled in part by the lifting of the FDA's black box warning about HRT risks, sales of estradiol patches in the US have shot upward. More than 142 million units of the patches were sold in 2025 versus 46.5 million in 2020. Suppliers are failing to keep up with demand—11 patch products were in short supply in early 2026. (Some users may experience a paywall.)

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

FDA removed its cardiovascular risk warning on testosterone products in 2025

The change came a decade after the FDA added the label. Recent work, including a gold-standard randomized trial, found that men receiving the products had similar cardiovascular risk levels as men taking placebo products. Testosterone, however, may hold other health risks, including infertility.

Testosterone therapy can cause infertility, and has been explored as a contraceptive

Augmenting testosterone with testosterone hormone therapy suppresses sperm production, and the resulting infertility is permanent in some men. Though a high level of testosterone inside the testicles is essential for fertility, testosterone supplements suppress the production of the pituitary hormones that leads to that natural testosterone production in the testicles—causing infertility.

Critics of concierge medicine argue it's worsening physician shortages and expanding inequity

Some research suggests that the average wait time for a primary care visit in major US cities can be 21 days. Subscription-based medical practices offer faster in-person and virtual appointment options, but the price barrier to this type of service may worsen inequity in healthcare access. (Some users may experience a paywall.)

Various pollutants may be contributing to a male infertility crisis

Male infertility, due to declining sperm counts or quality, accounts for about half of the cases of infertility among couples. Recent research has found that global sperm counts fell, on average, by 1.2% per year between 1973 and 2018—from 104 million to 49 million per milliliter. From 2000, this rate of decline accelerated to more than 2.6% per year. (Some users may encounter a paywall.)

Doctors are prescribing social activities—and seeing good results

Physicians, especially in the UK, are asking patients what they enjoy and then prescribing a consistent regimen of doing that type of activity to improve fitness and overall health, including community exercise classes, volunteering, and spending time in nature. This approach may provide better incentives to stick with an activity.

Gender-affirming hormone therapy cues changes similar to puberty

When HRT is part of gender affirmation care, people receive regular doses of estrogen or testosterone to alter hormone levels to more closely align with those of cis individuals of that biological sex. HRT may affect voice pitch, body hair, bone density, and more. Many of those changes are not reversible with the cessation of therapy, though the effects may diminish.

Estrogen is a really important hormone for men, too

Many people may be familiar with the idea that too much estrogen can cause infertility and other complications, including erectile dysfunction, but too little estrogen is also a significant medical concern because it can result in a reduced sex drive and limit overall growth.

Health problems are being misdiagnosed as perimenopause symptoms

Symptoms of menopause and perimenopause (the premenopause period) can be varied enough that clinicians dismiss them in patients in their mid-30s and onward as just a symptom of hormone level change. In this story, a woman's itching was dismissed as a hormonal change, but after two years and 11 separate doctor consultations, was diagnosed as cancer. (Some users may experience a paywall.)

How fantasy baseball fights the loneliness epidemic

Experts believe the erosion of traditional community organizations has led to a loneliness epidemic. This deep dive explores how fantasy baseball has filled the gap for some men, providing a stand-in social network.

Deepfake videos impersonating real doctors are spreading false medical advice

More than 100 videos, found primarily on Instagram and TikTok in August 2025, promoted products related to beauty, wellness and weight loss. While TikTok removed 94% of content violating its policies on AI-generated content, these deepfakes were watched and shared before removal, undermining public trust in medicine.

Doctors ignored women's pain as a nurse replaced their fentanyl with saline

This five-part podcast series, produced by Serial Productions, focuses on the experiences of women undergoing fertility treatments at a Yale clinic where a nurse secretly replaced pain medication with saline solution. This led to women experiencing excruciating pain during procedures, but the clinic downplayed or ignored their complaints.

Rural vs. urban: Exploring the digital health divide

Though digital health tools (DHT) hold potential to transform healthcare accessibility, their adoption varies across urban and rural landscapes. This comprehensive study, drawing from the 2019 Health Information National Trends Survey, evaluates the...

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Electronic trading transformed investing, ushering in a new era for retail investors in which average Americans could research stocks online and then use early platforms like StreetSmart and E-Trade to conduct their transactions

In the early 1990s, stock brokerages knew that online trading would be a great equalizer, creating opportunities for more individuals to buy and sell stocks.

A man with organ failure used AI to speed discovery of his miracle drug

David Fajgenbaum had a few months to live after a diagnosis with a rare form of Castleman's disease. By studying his blood, medical records, and broader literature, he was able to identify the cause of his condition and a treatment. He's been in total relapse for ten years.

Arnold Schwarzenegger fueled a lot of the interest in strength training, beginning in the 1980s

This was notable because clinicians around the 1950s thought that lifting heavy weights was bad for health, dampening muscle-strengthening interest that dates back to the ancient Greeks. Beyond Schwarzenegger-inspired interest and the popularity of Venice Beach bodies, the weight training movement also later gained momentum due to accumulating scientific evidence and the rise of entities like Crossfit. (Some users may experience a paywall.)

How did the pandemic affect mental health?

Read this research brief to learn more about why heightened mental health and substance use concerns persist three years after the outbreak of COVID-19. According to a recent survey, the vast majority of American adults view the nation as facing a...

Home allergy tests don’t work well and experts urge caution

Doctors do not recommend at-home allergy test kits because their results may be inaccurate and confusing, and lead people to make lifestyle changes that are not warranted. Tests that require sending in a hair sample, for example, will not be helpful because hair does not have the relevant antibodies that blood testing would detect.

Frictionless online gambling platforms accelerate compulsive behavior

As of late 2025, as much as 95% of bets are placed online, where "always on" betting and a variety of formats, such as prop bets and parlays, encourage users to keep participating. Experts warn that the normalization of gambling through advertisements also reduces the perceived danger of addictive gambling.

The science of spring fever

Researchers have confirmed what people have sensed for ages: Our emotions during the springtime can go a little wild. This piece breaks down the impact of the seasonal transition on our bodies and prescribes a few ways to mitigate the effects.

Drugs in space: the pharmacy orbiting the Earth

Researchers are developing pharmaceutical solutions for astronauts, whose bodies may not respond the same way in space as they would on Earth. Similar to how microgravity causes changes to astronaut physiology, the environmental shift enables new...

Trader Joe's breaks every rule of modern retail

The successful grocer doesn't do e-commerce, delivery, or coupons. And yet Americans are still obsessed with Trader Joe's.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

20,000 letters to the advice columnist 'Dear Abby' provide insight into prevailing sex, religion, and LGBTQ fears, anxieties, and concerns from the 1950s onward.

While the first exchange-traded fund (a 'basket' of different assets that can be bought and sold on a stock exchange) in the US only launched in 1993, the global ETF market has grown to more than $10T in the short time since.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

Children are now three times more likely to say they want to be a YouTuber when they grow up than an astronaut, with some even attending 'YouTube camps' that teach kids how to create content for the platform.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

The distributor behind 'Rocky Horror' pulled the film from its scheduled national release, believing it would be a failure, though it eventually amassed a dedicated fanbase through midnight showings, a trend that continues over 50 years later.

Despite being favored by 87% of Americans, Congress does not have term limits.

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

Double world record holder Hunter Ewen helped conquer his fear of balloons, called globophobia, by training to win Guinness World Record titles for balloon inflation.

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

In its famous catalog, Sears sold $600 DIY house kits from 1908 through the 1940s, resulting in an estimated 100,000 'Sears and Roebuck homes.'

In 1963, a basement renovation in Turkey revealed a passageway to a hidden, multilevel underground city that once housed as many as 20,000 people

The price of gas is a composite made up of several different factors, with the federal gas tax making up less than 20% of what drivers pay at the pump.

The identity of the Tank Man in the iconic photo from the 1989 Tiananmen Square protests remains unknown and was possibly killed.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.