Teddy Roosevelt was given a daily dose of saccharin

Saccharin was widely used in WWI when sugar was rationed

The substance was discovered by chemists in 1878, but its use became more common during World War I and also afterward as a result of sugar rationing. It had become a typical household item in the US and Europe by 1917. During World War II, the artificial sweetener again saw significant popularity.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Listen to how the 1902 'poison squad' experiments changed food safety in America

As part of government research, a group of young men were paid to eat standard American food—replete with food additives like borax and formaldehyde—which revealed the dangers of unregulated food. The work was led by the first FDA commissioner, Harvey Wiley, who helped end the "century of the great stomachache."

Michael Sveda discovered cyclamate by accident

When this lab researcher brought his hands to his lips to smoke his cigarette in 1937, he tasted something sweet, which he called cyclamate. It was quickly used in diet sodas, but it was banned from the US in 1969 after being linked to rodent bladder cancer in lab experiments.

The forgotten campaign to replace the Teddy Bear with 'Billy Possum'

After a 1909 pre-inauguration dinner for incoming President William Howard Taft featured possums and potatoes as the main course, Susie W. Allgood wanted to produce and market an alternative to the Teddy Roosevelt-inspired teddy bear: Billy Possum. Kids thought it looked too much like a rat.

Unlike its Mexican counterpart, American Coca-Cola contains high-fructose corn syrup rather than sugar

There are a few reasons why American Coke turned away from sugar in the 1980s, but none of them are related to consumer health. This Reader's Digest article breaks down the history behind Coke's recipe change, explaining why the company continues using high-fructose cough syrup.

Teddy Roosevelt’s intervention helped save a brutal early version of football

In 1905, President Theodore Roosevelt pressured college leaders to reform football amid public outrage over 18 player deaths. His push led to rule changes—like the forward pass—that reduced violence and ensured the sport’s survival.

Roosevelt wrote a nationally syndicated newspaper column 6 days a week for 27 years

Roosevelt's My Day column was launched in late 1935 and ran nearly every day until shortly before her death in 1962. It began as an account of her daily life but grew into one of the most widely read opinion columns in the country, with 4 million readers at its peak.

See how much daily sugar substitute intake the FDA considers to be safe

The agency states in this PDF graphic that a person weighing about 132 pounds would have to consume roughly a couple dozen sweetener packets daily—or more—to reach unsafe levels of consumption. The accumulated consumption would be across all sources, including diet beverages, sugar-free candies, and actual packets added to coffee.

Theodore Roosevelt is considered by many to be the "first modern president"

Roosevelt transformed the presidency by expanding executive power beyond conventional norms, arguing that the president could act in the national interest unless expressly forbidden to do so. His energetic leadership, media use, and policy activism expanded the office's role and prestige.

'The most important single ingredient in the formula of success is knowing how to get along with people.'

- Former President Theodore Roosevelt's (1858–1919)

The 22nd Amendment was a reaction to Roosevelt's four terms

After Franklin D. Roosevelt won four elections, Congress moved to prevent future presidents from holding power indefinitely. Ratified in 1951, the 22nd Amendment set a firm two-term limit as a safeguard against extended presidencies.

The FBI surveilled Roosevelt for decades, suspicious of her civil rights and political work

J. Edgar Hoover's FBI maintained a large file on Eleanor Roosevelt, monitoring her involvement with civil rights groups, connections to progressive causes, and vocal opposition to McCarthyism. Although a formal investigation was never initiated, Hoover regarded her as a person of interest for most of her adult life.

Some say baseball's drug problem goes back to the late 1800s

At age 32, pitcher James “Pud” Galvin was feeling tired and decided to take "the Brown-Séquard elixir," which contained a testicular fluid from dogs and guinea pigs, believed to invigorate tired bodies. It might've worked: Galvin pitched a two-hit shutout the next day.

Leonard Thompson was the first human to receive an insulin injection for diabetes

In January 1922, the 14-year-old was the first person to receive an insulin injection to treat diabetes, just months after insulin was isolated in dogs and used to treat their induced diabetes. Thompson had an allergic response to an apparent impurity in the injection, but his second dose, 12 days later, was a success.

Rachel Carson didn't argue for wholly organic farming

Her 1962 book, “Silent Spring,” inspired many people to consider the chemicals used to grow their food, but Carson didn’t think that manufactured fertilizers needed to be banned from farming, writing that “The ultimate answer is to use less toxic chemicals so that the public hazard from their misuse is greatly reduced.” When she testified to Congress in 1963, she said, “I think chemicals do have a place.”

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted and led to authorities' suspicions he was conspiring with the Russians

The 1794 incident involved André-Ignace-Joseph Dufresnoy, a French army physician researching the plants' potential medicinal properties. Rhus radicans is a scientific name for the plant, though it's commonly called Toxicodendron radicans.

The CIA tried to poison Castro’s milkshake

During the Cold War, the CIA engaged in a series of "creative" attempts to assassinate Cuban leader Fidel Castro—including poisoning his daily chocolate milkshake with botulinum toxins. It was not successful.

'Rocky Road' was designed to help people cope with the stock market crash

In 1929, ice cream maker William Dreyer marketed Rocky Road as a sweet treat intended to distract consumers from the poor state of the economy. (Some readers may experience a paywall.)

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted, leading authorities to suspect he was conspiring with the Russians.

James Garfield's 79-day decline hooked America on news updates

After he was shot while departing Washington, DC, in 1881, the president was treated for his wounds and cared for at the White House. Since 1861, telegraphs had spanned the continent, and the Associated Press pooled sources to share telegraph news. The public, seeking updates on the president's condition, was able to receive them regularly for the first time due to this network, laying the foundation for the continuous news cycle.

'Mental hygiene' was the 1843 term for mental health

It was coined by American psychiatrist William Sweetzer to reference the same idea as personal hygiene. Mental hygiene, in Sweetzer's view, needed to be maintained in the same way people attend to their personal cleanliness, an idea that was supplanted by better understanding of the complexities of mental health disorder causes in the decades that followed.

How a skin cancerous growth shifted an initially skeptical President Reagan on the ozone crisis

While a 1985 Nature study revealing the Antarctic ozone hole jolted public concern, Reagan's administration was more focused on the Cold War than on environmental policy. His health scare and the market potential for developing alternatives to chlorofluorocarbons helped turn the tide, leading to the Montreal Protocol's unanimous ratification by a bipartisan Senate in 1988.

Unpacking Thoreau's diet, which once included a woodchuck

The writer's diet was notoriously simple, preferring an inexpensive combination of rice and vegetables to meat, though he usually ate it when offered. In "Walden," he mentions eating a woodchuck after it got into his beans, which one Thoreau biographer said was likely true.

The favorite restaurants of former US presidents

Curious about the eating habits of past commanders-in-chief? From George Washington to Barack Obama, discover the food preferences of former US presidents. Find out who liked to go out vs. stay in, where they frequented, what they ordered, and how they spent their time in each establishment.

JJ Schildkraut theorized depression is linked to brain chemical imbalances—in 1965

Schildkraut was one of the first to put forward this idea, which stemmed from lab animal research. A decade later, researchers published the first landmark paper on fluoxetine—better known by trade name Prozac—which increases serotonin levels in the brain.

Fiji's 'quiet' diabetes crisis

Across the Pacific archipelago of Fiji, diabetes often avoids diagnosis until amputation or death is imminent. Fiji's government has said nearly 30% of its population has diabetes, and, in 2019, related amputations accounted for 40% of the country's hospital operations. This "sugar disease" may have such a stronghold on the archipelago, which has a physically active culture that prizes locally sourced foods, due to cost, with processed foods being much cheaper than alternatives.

Mark Twain spent decades feuding with the US Postal Service, convinced its costs and regulations were bureaucratic overreach.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

Abraham Lincoln was almost assassinated weeks before his inauguration as he traveled from Illinois to DC through Baltimore in 1861; it took two independent claims for Lincoln to be convinced the threat was real

70 years ago today, city officials in Santa Cruz, California, banned rock 'n' roll to protect its youth from corruption after witnessing a 'provocative' concert the night before.

The idea for the Federal Reserve was conceived in secret in 1910—with bankers donning duck hunt gear for disguise while traveling to a remote country club on Georgia's Jekyll Island

Jimmy Carter signed a 1978 bill that legalized home brewing, a move credited with kick-starting the craft beer industry.

After the Boston Tea Party, colonists switched to coffee, which became the main morning drink for revolutionaries.

Many legends about George Washington, including his supposed wooden teeth and the story of cutting down the cherry tree, lack evidence.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

20,000 letters to the advice columnist 'Dear Abby' provide insight into prevailing sex, religion, and LGBTQ fears, anxieties, and concerns from the 1950s onward.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Before writing 'Walden,' transcendentalist Henry David Thoreau nearly burned down his hometown with a campfire that grew out of control.

Mid-century modern graphic designers, known for their bright colors and bold lines in advertising, also found success with children's books.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

Up to a million Girl Scouts sell about 200 million cookie boxes every spring, generating $800 million, largely because refusing a child is frowned upon

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

In 2025, four executives from large tech companies were given positions in the US Army Reserves—including Palantir Chief Technology Officer Shyam Sankar, which reinforced Palantir's ties with the US military and its role as a leading defense partner.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients.