The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Explore how the placenta acts as lungs, kidneys, and more in the womb

This temporary organ, formed from maternal and embryonic tissue, ultimately attaches to a fetus via the umbilical cord. It transports nutrients, oxygen, antibodies, and more from the mother to the developing fetus. It also carries carbon dioxide and waste away from the fetus. The placenta—which forms only during pregnancy—is expelled during childbirth, or it needs to be removed to prevent toxic maternal infections and extreme blood loss.

Explore the abundance of different types of cells in the human body

Lacking a nucleus and other organelles to maximize space for oxygen-carrying hemoglobin and enhance maneuverability through narrow capillaries, there are about four times as many red blood cells and platelets as all other cell types in the body combined. However, about half of the body's cell biomass consists of skeletal myocytes, or muscle fibers.

Only about 0.0001% of sperm, on average, successfully reach the uterine cavity

We've evolved to make pregnancy a complex and difficult process. From the initial development of the blastocyst, to the energy and nutrients needed to grow a new human, our bodies are both fighting and supporting fetal development.

Cells cannot grow forever due to escalating inefficiency in transporting chemicals

As cells get larger, their volume grows much faster than the surface area through which nutrients and waste products pass, creating a bottleneck that eventually causes cells to die. This forces nearly all organisms visible to the naked eye to comprise enormous numbers of smaller cells, such as the approximately 30 trillion found in the average adult human.

Stem cells become specialized cells through the activation or silencing of specific genes

After fertilization, when a sperm cell fuses with an egg, the resulting stem cell is described as totipotent—capable of transforming into any type of body cell or embryonic structures (e.g., placenta). Once differentiated into multipotent cells, they can only specialize further within specific cell type families, such as hematopoietic cells that become platelets and red and white blood cells.

Fetal development, week by week

Gestation is the period of time between conception and birth when a baby grows inside the mother's womb. Changes occur constantly over the course of these 40 weeks. At week 17, for instance, the skeleton of a fetus begins changing from soft...

The human body in 3D

Zygote Body is a free human anatomy tool that allows users to explore the intricacies of the human body in stunning detail. With the click of a mouse, users can isolate by body system or view anatomical structures from any angle. Check out this...

‘Hope for Healing’: The first-ever use of an in utero stem cell treatment

In 2023, researchers at UC Davis performed the first-ever fetal stem cell transplant, attempting to cure a case of spinal bifida prior to childbirth using stem cells derived from the placenta. The trial, and others including an effort to treat muscular dystrophy, highlight the potential power of stem cell therapy.

Adhesion molecules and intercellular junctions allow cells to connect together

While some organic structures are mostly composed of non-cellular components (e.g., collagen and calcium phosphate minerals in bones), tissues and organs composed of connected cells rely on specialized proteins and connections to create watertight seals that protect cells within the interior from environmental molecules.

Necrosis is the unplanned death of cells and the tissue they comprise

If cells die prematurely due to a lack of blood flow, injury, or disease, they and their organelles can swell, leading to rupture of the surrounding cell membrane. This releases the cell's contents into the surrounding tissue, causing inflammation and damage to neighboring cells.

Learn how chloroplasts—the photosynthesis factories—may have once been independent cells

Possessing DNA of their own that differs from that of their host cell and surrounded by cellular membranes like those observed in bacteria, chloroplasts are believed to have evolved from a cyanobacterial cell. The endosymbiotic theory explains that these organelles were absorbed into larger cells, leading to the photosynthetic cells seen today.

Cells create more organelles and duplicate their genetic material before dividing

As part of the cell cycle, this ensures that after mitosis—the process of cell division—the two resulting daughter cells possess the tools necessary to complete the functions of their parent cell, including accumulating energy and making proteins. During meiosis, four egg or sperm cells are created, each with half the parent cell's DNA.

The plasma-selling industry is expected to reach $50B by the end of the decade

About 55% of your blood volume is plasma, the liquid part of blood created from water, proteins, minerals, and salts absorbed through the digestive tract. This 49-minute podcast episode explores the business of plasma—part of a global industry expected to be worth $50B by 2029.

Watch how DNA is packaged to a 10,000th of its original size in a cell

In humans, the 2-meter (6.56-foot) molecule wraps around spool-like proteins called histones, forming beads—nucleosomes—that fold up into fibers. These fibers—chromatin—form loops through folding that compress into larger fibers, which tightly coil together to form a chromosome.

Modern pregnancy tests detect a specific hormone in a woman's urine or blood

They pick up human chorionic gonadotropin, in either blood or urine. The hormone is produced by a woman's reproductive tissues during pregnancy.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

The body's master clock has 20,000 neurons

The suprachiasmatic nucleus, the master clock in mammals, has 20,000 neurons that help maintain the light-dark cycle in the body. Among its jobs: It receives light input information from the retina and then signals peripheral body clocks to act on this information, driving everything from body temperature to hunger.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

In 1984, a dying infant lived for three weeks with a baboon heart

Pediatric-sized hearts are very hard to find. They're about the size of a walnut. When a premature baby girl was born with a fatal heart defect in 1984 her care team transplanted a 7-month-old baboon's heart into the patient. The organ was not genetically modified but still the infant lived for several weeks. This roughly hour-long documentary from the medical institution, features the patient's mother, clinician, and more discussing the controversial procedure and aftermath.

Earth’s major tectonic plates make up 95% of its surface

Tectonic plates are pieces of Earth’s lithosphere, which consists of the crust and the solid, upper layer of the mantle. Segments of major plates can break and form minor or microplates, whose total number varies based on ongoing geological activity.

An artificial ‘lung’ protects the glass structures making up Biosphere 2

Although confined from much of the surrounding environment, B2 allows sunlight to enter, enabling its plants to engage in photosynthesis. Expansion chambers were built to protect the facility's integrity by managing changes in gas pressure resulting from temperature fluctuations.

The origin of cyborgs

The term "cyborg" was coined in a 1960 academic paper discussing what alterations humans would need to undergo to survive in extraterrestrial environments, a venture far "more logical than providing an earthly environment" in space. According to authors Manfred E. Clynes and Nathan S. Kline, Cyborgs with a capital C have incorporated exogenous components that extend their ability to adapt to new environments. Read the paper here.

South American lungfish has the largest animal genome, with 91 billion base pairs

This genome is 30 times larger than a human's due to significant amounts of "junk DNA" and jumping genes, or transposons. Transposons can jump or copy over to other parts of a genome and may aid adaptation.

See this 201-level explanation about mitochondria and mitochondrial replacement therapy

This 2022 academic presentation from Stanford University's Dr. Gregory Enns offers a detailed overview about mitochondrial therapy approaches. Enns, a pediatric geneticist, explains how well-functioning mitochondria support the human body.

What we know about the mysterious colossal squid

The colossal squid, the world's largest invertebrate, remained hidden from human discovery until nearly a century ago. Explore the world of the enormous and mysterious creature, including its features, habitat, and scientific significance. You can even plan a visit to the Museum of New Zealand Te Papa Tongarewa and marvel at a real-life display.

Watch a visualization of the formation of the planets

The nebular hypothesis proposes that a swirling cloud of gas and dust coalesced into a dense center, forming a star amid nuclear fusion. Lighter elements were blown far from the star while heavier elements remained nearby, serving as primary materials for terrestrial and jovian planets, respectively.

Schizophrenia is being studied with pea-sized 'mini-brains'

Brain organoid research is enabling researchers to study distinct electrical firing patterns associated with schizophrenia. These "mini-brains" that are constructed in the lab from patients' cells could lead to better diagnosis approaches and drug development.

Watch what the Ebola virus does inside our cells and organs in order to spread and survive.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Explore our favorite visualization of the immense scale of space, from an astronaut to the size of the observable universe

See a 3D reconstruction of Tenochtitlan, the Aztec capital that was home to an estimated population of 200,000 to 400,000.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Massive 3D printers have been used to build homes by stacking layers of 'concrete toothpaste,' a fire-resistant material that effectively insulates against outside noise.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

While the sun's gravity keeps the planets in orbit, their gravity also pulls on the sun, causing it and everything else in the solar system to orbit around a mutual balance point called the barycenter—the true center of the solar system.

Lesser-known phobias include turophobia, or the fear of cheese, and nomophobia, the fear of being without your cell phone.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Use this tool to calculate the dollar value of your parental mental load, from meal planning to coordinating after-school care, then see resources that help generate solutions.

Sony set the standard for cylinder-shaped batteries when it repurposed manufacturing equipment used to make rolls of magnetic recording tape.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in terms of casualties, forces mobilized, and displacement of civilians.

In 2025, four executives from large tech companies were given positions in the US Army Reserves—including Palantir Chief Technology Officer Shyam Sankar, which reinforced Palantir's ties with the US military and its role as a leading defense partner.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

A century of Billboard issues documenting the evolution of popular music.

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.