‘Hope for Healing’: The first-ever use of an in utero stem cell treatment

Stem cell therapies show promise in treating spinal injuries

Researchers have long hoped to use stem cells in regenerative medicine to help patients with spinal cord injuries restore sensation and movement. A 2024 clinical trial illustrates how stem cells derived from patients' fat tissue could help spur the creation of new cells in the spinal cord.

Gene therapy, a hope of the Human Genome Project, saves a baby's life

A baby with a rare genetic disorder received a bespoke gene-editing treatment using CRISPR technology. The case highlights the potential of personalized medicine for rare diseases, building on the foundation set by the Human Genome Project.

In vitro gametogenesis: using induced stem cells to fertilize eggs

Using stem cells from skin and mouth cells could save hopeful parents time and money and spare egg donors from significant amounts of discomfort throughout the process. There are potential consequences, not just for infertility treatment, but for the ability to create customized cells of any type.

Four frozen embryos in the US were created via 3-parent IVF technique

Columbia University researchers created four embryos using mitochondrial replacement therapy for four female patients who didn't want to pass on mitochondrial diseases to their children. Yet US law restricts the researchers from implanting the embryos so they remain frozen. (Some users may encounter a paywall.)

Using artificial wombs to improve preterm infant health outcomes

Researchers at a hospital in the US have successfully used artificial wombs to care for preterm lambs and are now looking at the possibility of human trials. This nine-minute video includes interviews with the researchers and explains the reasoning...

How to turn any cell of the body into a stem cell

Scientists have developed techniques allowing them to 'reprogram' any cell in the body into an induced pluripotent stem (iPS) cell, which can be used to create either more stem cells or specialized cells for use in experimental medical treatments. This page gives readers a brief introduction to the history of iPS cells, what researchers are studying with iPS cells, and challenges associated with iPS research.

Scientific advances are unlocking a wide range of alternatives to IVF

From refined artificial insemination and microsurgical sperm extraction to experimental uterine transplants, scientific innovation is rapidly advancing potential fertilization technologies. But they come along with costly trials, some ethical dilemmas, regulatory issues, and more.

Bone marrow transplants were the first successful type of stem cell therapies

Bone marrow contains two types of stem cells: Skeletal (develop into bone, cartilage, and more) and hematopoietic, which create new blood cells. The latter are critical in bone marrow transplants, and give the recipient the ability to create healthy blood cells to fight diseases like leukemia.

What conditions can be treated with stem cells?

Stem cell research is a global enterprise, and much of the work is being done in Europe. This page gives readers a good sense of the medical conditions stem cell researchers in Europe focus on, and the specific research challenges they address. This page also offers links to in-depth information about many of the research projects.

The scandal that rocked stem cell research

In 2014, a Japanese research group published a paper suggesting ordinary cells could be reverted to pluripotent stem cells by subjecting them to external stressors. The results generated interest but could never be replicated. The lead researcher was accused of fraud, and the group’s supervisor committed suicide.

Mice were able to regenerate retinal cells in the lab—a breakthrough for mammals

Using gene therapy, a team of Korean researchers has enabled retinal regeneration in mice by blocking the intercellular transfer of a single inhibitory protein. This 2025 finding creates a new potential direction for treating retinal diseases. The work, which is still in animal studies, is projected to enter early-stage clinical trials in the next few years.

The first successful IVF pregnancy was in the United Kingdom in 1978

Gynecologist Patrick Steptoe and his collaborator Robert Edwards, a biologist, attempted to fertilize a human egg cell in a petri dish 101 times before finally succeeding. This resulted in the birth of Louise Brown—at the time referred to as a "test tube" baby—in 1978, who was born into the spotlight.

'Artificial embryos': The hidden steps in forming a spine

Somitogenesis is the process by which segmented body structures like vertebrae form in embryos. While the process is well understood in animals like mice or zebrafish it is difficult to study in humans. But now, researchers have created a model of somitogenesis, using pluripotent stem cells, called an axioloid.

A clinical trial is underway in 2026 to help kidney transplant recipients avoid a lifetime of immunosuppressing drugs

This later-stage clinical trial, in Chicago and Taiwan, evaluates the efficacy and safety of a new cellular therapy that may be swapped in for immunosuppressing drugs among kidney transplant recipients. The study randomizes people to either receive standard immunosuppressants or this cellular therapy and fewer immunosuppressants. It only includes kidney transplant recipients receiving organs from live donors so transplant surgery timing won't hinge on the unpredictable schedule of performing surgery and follow-up care when a donor dies.

How to repair a baby’s broken heart

A rare disorder that prevents some babies from getting enough oxygen to their organs can be repaired through a series of three intricate surgeries. This article and graphic explain the process behind correcting single-ventricle defects, also known as SVDs.This disorder happens when one of the heart's lower chambers doesn't work correctly, resulting in deoxygenated and oxygenated blood circulating the body rather than just the latter.

Xenotransplants are an experimental last resort for the terminally ill

David Bennett Sr., the world’s first genetically modified pig heart transplant recipient, explained his reasoning to his University of Maryland Medical Center care team in 2022 regarding why he accepted a pig organ: He was dying and ineligible for a human heart transplant so this was a last-ditch effort, he said. He died two months after receiving the heart.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Fecal transplants can help treat infections

Fecal transplants aim to transplant healthy gut bacteria into ill patients by transferring (literally) samples of human waste from a healthy patient to a sick patient. The technique has been shown to cure otherwise deadly Clostridioides difficile (C. diff) infections and is being studied for a range of other uses.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Each day, about 60 US pregnancies end in stillbirth

This online memorial for families who experienced the unexpected death of a fetus 20 weeks or older is the result of ProPublica reporters inviting 60 families to share their baby's name and answer some questions about their unfulfilled wishes for their children. About 21,000 babies are stillborn in the US annually. About the same number of children die in the US during their first year of life.

The first neural devices were cochlear implants, designed to treat hearing loss

Neural interfaces connect with our nervous system to restore or enhance abilities, such as hearing or movement. These neuroprostheses have enabled the restoration of mobility, communication, and activities of daily living that might otherwise require a caregiver.

Open brain surgery is not required for BCIs inserted via blood vessel injection

Synchron's brain-computer interface, the Synchron Switch, takes advantage of preexisting medical devices, such as stents and catheters. Cells grow over the device over a 90-day period, incorporating it into the vessel wall and minimizing clots.

Chagas disease can be transmitted to a fetus during pregnancy

Researchers estimate that 63 to 315 cases of congenital Chagas disease occur annually in the US. Roughly 20 to 30 percent of all Chagas disease cases will progress to cardiac or gastrointestinal disease.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

Touch helps newborns regulate stress, gain weight, and feel less pain

Conclusions from this 2024 analysis from a team of Danish researchers included that touch interventions were particularly useful for newborns in regulating cortisol levels, helping newborns gain weight, and reducing pain. (Some users may experience a paywall.)

See the first dog ever treated with insulin—a peptide

Frederick Banting and his graduate student Charles Best were the first to isolate the peptide insulin from dogs. They induced diabetes in the animals and then treated them with this peptide.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

Venture capital is a form of funding provided to early-stage companies with high growth potential, typically in exchange for an equity (or ownership) stake

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

In 1945, Surrealist artist Salvador Dalí and legendary animator Walt Disney began collaborating on a short film that was not completed until 2003, years after both men had died.

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

Long before Major League Baseball began allowing instant replay for balls and strikes, an umpire reluctantly used the technology to determine whether a hit was a home run, a move that inadvertently ushered in a new era for the sport.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The American Society of Civil Engineers' infrastructure report card gave the US a C in 2025, its highest grade since the project launched in 1998.

Brandi Chastain, the star of the 1999 US victory over China in the 1999 Women's World Cup, was a last-second choice to take the penalty kick that sealed the victory.

70 years ago today, city officials in Santa Cruz, California, banned rock 'n' roll to protect its youth from corruption after witnessing a 'provocative' concert the night before.

Explore fun facts from the USPS, including unique post office buildings, a stamp that traveled past Pluto, and more.

Legendary architect Frank Lloyd Wright designed the SC Johnson headquarters in Wisconsin, aiming to make a cathedral-like workplace