In 1984, a dying infant lived for three weeks with a baboon heart

Xenotransplants are an experimental last resort for the terminally ill

David Bennett Sr., the world’s first genetically modified pig heart transplant recipient, explained his reasoning to his University of Maryland Medical Center care team in 2022 regarding why he accepted a pig organ: He was dying and ineligible for a human heart transplant so this was a last-ditch effort, he said. He died two months after receiving the heart.

Donated hearts remain viable three times longer now with new tech

Advances in organ perfusion systems have significantly lengthened the amount of time donated hearts can remain viable for transplant, expanding the possibilities for donor organs to wider geographic areas. "Heart in a box" devices, developed in recent years, enable effective oxygen flow in the donor heart during transport, which means that hearts can now travel farther to potential recipients and still be in good condition.

Pig heart valves have been placed in humans since 1965

The first successful use of a pig heart valve in a human was reported in 1965. This 2015 video details why humans have been able to use pig animal valves for so long with good results and how that differs from what's needed for whole organ transplants.

How to repair a baby’s broken heart

A rare disorder that prevents some babies from getting enough oxygen to their organs can be repaired through a series of three intricate surgeries. This article and graphic explain the process behind correcting single-ventricle defects, also known as SVDs.This disorder happens when one of the heart's lower chambers doesn't work correctly, resulting in deoxygenated and oxygenated blood circulating the body rather than just the latter.

How heart transplants work

Heart transplants require an old heart to be removed and a new one to be installed without killing the patient. How does that work? In this easy-to-understand five-minute video, learn each step of the intricate process, from donor matching to the preservative solution a heart is doused in while it is transported.

One man lived with a gene-edited pig kidney for 271 days, a record

In October 2025, Tim Andrews had his gene-edited pig kidney removed because it was no longer working well. He had the transplanted organ for 271 days—surpassing the prior record of a patient who functioned with one for 130 days. Andrews remains on the kidney transplant wait list to receive a donated kidney from a human, but he has a particularly hard-to-match blood type, making it challenging to get the organ.

The first successful organ transplant was performed in 1954

The successful kidney transplant procedure, at what's now-called Brigham and and Women's Hospital, ushered in a new medical era and gave hope to patients with organ failure. The recipient, 23-year-old Richard Herrick, lived eight more years after receiving the donated organ from his living twin brother, Ronald.

Using artificial wombs to improve preterm infant health outcomes

Researchers at a hospital in the US have successfully used artificial wombs to care for preterm lambs and are now looking at the possibility of human trials. This nine-minute video includes interviews with the researchers and explains the reasoning...

Grieving primate mothers will carry dead infant for long after death—and others will comfort her

An examination of infant corpse carrying practices among non-human primate mothers found that 40 species of primate mothers will carry around their dead infant for days, weeks, or even months. In some cases, a grieving primate's group members would provide grieving support—hugging or staying close to mothers who experienced a loss.

Eight British children have been born via mitochondrial replacement therapy

In July 2025, a decade after British lawmakers signed off on allowing three-parent IVF, scientists announced that eight healthy babies had already been born using this approach. The news was included in a pair of research articles published in a peer-reviewed journal that noted the oldest kids were already more than two years old, and that they were hitting developmental milestones as expected. (Some users may encounter a paywall.)

‘Hope for Healing’: The first-ever use of an in utero stem cell treatment

In 2023, researchers at UC Davis performed the first-ever fetal stem cell transplant, attempting to cure a case of spinal bifida prior to childbirth using stem cells derived from the placenta. The trial, and others including an effort to treat muscular dystrophy, highlight the potential power of stem cell therapy.

A 13-year-old was declared brain-dead yet went through puberty on a ventilator

This podcast details Jahi McMath's highly controversial case. She was declared brain-dead in 2013 following surgical complications, but her family, citing religious beliefs, kept her connected to a ventilator for the five years that followed. She continued to grow and went through puberty before being issued a second death certificate in New Jersey.

How personalized gene-editing saved a baby's life

KJ Muldoon had a 50% chance of surviving a genetic mutation until doctors developed a one-of-a-kind gene-editing therapy. In an interview with one of the researchers behind the treatment, learn what it will take to make personalized genetic medicine possible for everyone.

Pig brain cellular activity was restarted hours after death in study published in 2019

Yale University scientists restored basic cellular activity and circulatory function in pig brains about four hours after death with a synthetic cocktail of preservatives and nutrients. This work— which didn't restart electricity activity in the brain or consciousness—could help advance future human stroke and brain injury treatments.

How the heart achieves its first beat

Scientists observed zebrafish embryos as they grew and isolated the several-second-long initial heartbeats to better understand this crucial moment in every heart's life. The zebrafish's heart starts beating 20 hours into their existence. Each heart cell activates electrically at random, without rhythm. As these cells mature, they become more sensitive to electrical charges; as they all fire, a rhythm is established and a pulse is born.

A man with organ failure used AI to speed discovery of his miracle drug

David Fajgenbaum had a few months to live after a diagnosis with a rare form of Castleman's disease. By studying his blood, medical records, and broader literature, he was able to identify the cause of his condition and a treatment. He's been in total relapse for ten years.

When was the first blood transfusion?

In the 1600s, an English doctor transferred the blood from one dog to another via quills. The procedure ended when one of the dogs died. This article details the early days of blood transfusions, which turned toward humans shortly after the 1666 dog experiment and involved putting the blood of a sheep into a human recipient (who reportedly survived the encounter).

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Each day, about 60 US pregnancies end in stillbirth

This online memorial for families who experienced the unexpected death of a fetus 20 weeks or older is the result of ProPublica reporters inviting 60 families to share their baby's name and answer some questions about their unfulfilled wishes for their children. About 21,000 babies are stillborn in the US annually. About the same number of children die in the US during their first year of life.

An 18th-century woman tricked doctors into believing she gave birth to rabbits

Mary Toft was a poor servant in Surrey who reportedly sought fame and money by perpetuating the story of her "monstrous birth." After having a miscarriage a month earlier, Toft claimed to still be pregnant and called obstetrician John Howard to witness her give birth to animal parts, including a cat without a liver, a rabbit’s head, the legs of a cat, and nine dead baby rabbits. Eventually, after fooling the court physicians of King George I, she confessed to orchestrating the births.

Why do humans have such long childhoods?

Humans have over twice as long childhoods than other animals with similar lifespans like whales and elephants. A human child can grow for nearly 20 years before they become a reproducing adult. Researchers believe there's a connection between long childhoods and human's unusually large brain size, though the science is not totally clear. Dive into what scientists know here.

At one point in the 20th century, more than a million Americans had pet monkeys

This choice to domesticate monkeys proved to be trickier than expected, and thus isn't a very appealing option for humans. Monkeys breed more slowly than other animals, while also being susceptible to diseases and challenging to contain.

The iron lung—a simple mechanical ventilator—was first used to treat polio

These breathing devices, developed in the late 1920s at Harvard, were used to treat polio patients with breathing difficulties. Watch this video describing how these negative pressure devices work.

Explore how the placenta acts as lungs, kidneys, and more in the womb

This temporary organ, formed from maternal and embryonic tissue, ultimately attaches to a fetus via the umbilical cord. It transports nutrients, oxygen, antibodies, and more from the mother to the developing fetus. It also carries carbon dioxide and waste away from the fetus. The placenta—which forms only during pregnancy—is expelled during childbirth, or it needs to be removed to prevent toxic maternal infections and extreme blood loss.

Which organs can you live without?

While there are some organs (such as the heart) that people simply can’t live without, there are other organs that can be removed without a huge impact. Patients who have their appendix removed, for example, experience no changes to their daily...

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

In 2023, at least 6 people were charged with stealing body parts

A recent case involving alleged trafficking in stolen human body parts charged that there was a nationwide network of individuals who bought and sold human remains. The charges alleged, among other things, that from 2018 through 2022, the manager of the morgue at Harvard Medical School's Anatomical Gifts Program stole organs and other parts of cadavers that had been donated for medical research and education. In late 2025, that Harvard morgue manager was sentenced to 96 months in prison.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

The tragic Pulitzer Prize-winning image 'The Vulture and the Little Girl' (1993) generated controversy, raised concerns about ethics in photography, and eventually led to the photographer's death.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

Double world record holder Hunter Ewen helped conquer his fear of balloons, called globophobia, by training to win Guinness World Record titles for balloon inflation.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

In 1945, Surrealist artist Salvador Dalí and legendary animator Walt Disney began collaborating on a short film that was not completed until 2003, years after both men had died.

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

A researcher recently discovered an interview from 1967 between groundbreaking journalist Joan Didion and the Grateful Dead, years before the band became an institution.

The animatronic shark from Steven Spielberg's 'Jaws,' the first modern blockbuster, was a complex underwater apparatus called 'Bruce.'

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

Many legends about George Washington, including his supposed wooden teeth and the story of cutting down the cherry tree, lack evidence.

Domino's Pizza's 30-minute delivery guarantee was responsible for the chain's 1980s surge, but it was discontinued after the company was found liable for delivery driver accidents.

Elk Cloner, the first computer virus to spread in public, was written as a practical joke by Richard Skrenta, a Pittsburgh high school student.

The first image of a black hole was captured by creating an Earth-sized virtual observatory from a network of eight radio telescopes.

Brian Wilson wrote the Beach Boys' 'Don't Worry Baby' for the Ronettes, but the legendary girl group rejected it.