'Barbie' drug melanotan II purportedly offers tanning without the sun—but it's very risky

Peptide TB-500, promoted for regenerative healing, is not FDA approved

Watch a board-certified sports medicine therapist detail his thinking about this synthetic peptide; he says it's "promising but unproven." He notes that this product is designed to mimic the natural protein thymosin beta-4, found in human and animal tissues, which promotes wound healing. TB-500 is classified as a research peptide for recovery, meaning it's not approved for human use and has not yet undergone rigorous human trials on its safety and efficacy.

The US FDA considered mitochondrial replacement therapy during 2014 hearings

An agency committee assessed if this approach could have undesirable ripple effects across multiple generations and whether a clinical trial involving this approach would be appropriate. As of 2026, the US has continued to prohibit this procedure though it is legal in other settings including the UK and Australia.

Ibogaine is being investigated for treating mental health issues and substance abuse

This compound, which is illegal to use in the US, has had promising results for patients who have tried it in other countries for substance abuse and mental health concerns. This psychoactive substance is not without risks, however; this TED talk points out it's also caused fatal cardiac arrhythmias and shouldn't be taken without medical supervision.

'Magic ink' is redefining the tattoo

One University of Colorado professor has developed an ink that can be "turned on" with exposure to UV light, and "turned off" with sunlight. While the ink could help those who want to hide their body art from family members or coworkers, there are potential uses for medical procedures.

Vitamin D supplement pills are linked to rising cases of vitamin D toxicity in the US

Vitamin D deficiency is common. But taking Vitamin D supplements in doses exceeding 4,000 IU/day (a measurement of vitamin biological activity) for prolonged periods can raise bodily concentrations of this vitamin to dangerous values. US National Poison Data indicates that the annual average of vitamin D poisonings from 2000-05 was 196, but this rose by 1,600% to 4,535 per year for the period of 2005-11.

Deepfake videos impersonating real doctors are spreading false medical advice

More than 100 videos, found primarily on Instagram and TikTok in August 2025, promoted products related to beauty, wellness and weight loss. While TikTok removed 94% of content violating its policies on AI-generated content, these deepfakes were watched and shared before removal, undermining public trust in medicine.

Combining two cancer drugs increased the life space of mice by 30%

A study shows trametinib and rapamycin, two drugs used for cancer treatment in humans, increased mouse lifespan when used together. The medications delayed the onset of cancer and reduced chronic inflammation, results that will be explored in future research.

Risks of GLP-1s include health side effects, counterfeit drugs, and more

This episode interviews researchers and patients who have used semaglutide to explore some of the potential risks associated with using the drug to lose weight. These include insurance challenges, health scares related to counterfeit versions of these drugs, and some users lose their ability to enjoy food.

Mineral and chemical sunscreens protect differently but both guard against UV damage

UVA rays age the skin, while UVB rays are more directly linked to skin cancer. Mineral sunscreens, with ingredients like zinc oxide, physically block rays, while chemical ones absorb UV and turn it into heat.

Photodynamic therapy is one current treatment for age-related macular degeneration

This laser-based treatment is used on advanced "wet" age-related macular degeneration patients, but it's now used less often than in the past because there are newer injection-based drugs to decrease abnormal blood vessel growth.

The history of the iconic Barbie doll

The 1959 debut of the Barbie doll changed the culture of toys permanently, and its many iterations have come to reflect, in a certain way, the aspirations of women around the world. But Barbie's unrealistic looks and plastic substance have prompted...

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Kava, kratom, St. John's Wort, and green tea extract present health concerns

Consumer Reports, which tests supplements for safety, urges consumers to avoid these four supplements due to safety warnings from researchers and public health authorities.

Scleroderma, which causes skin to harden and scar, has no FDA-approved treatment

It's an autoimmune disease that disproportionately causes worse complications in African American people for unknown reasons. It causes the body to overproduce collagen after the immune system attacks the body's own connective tissue, leading to excess collagen deposits and restricted blood circulation as small blood vessels are damaged. It can damage various organs, including the lungs.

'Blackout challenge' can cause brain damage or death in under 5 minutes

A social media trend that encourages viewers to asphyxiate themselves until they lose consciousness in the hopes of feeling "high" or euphoric has garnered the interest of teens and adolescents, with dangerous results. Variations of this deadly challenge have been adolescent trends every few years.

Saccharin was banned in Canada in the 1970s, but regulators may allow its use once again

The product, commonly known as Sweet'N Low, was banned in Canada in the late 1970s due to research indicating that the sweetener could cause cancer in lab rats. Subsequent studies have found that the rodent findings didn't hold true for humans, and so Canadian regulators state that they are considering updating their stance to allow the product to be added to certain foods (the product is currently allowed in the US).

Bright light therapy involves basking in 10,000 lux of light for 30 minutes each morning

Nothing is better than going outside and soaking up real sunlight. However, this is harder in winter, especially in very cold and cloudy regions. SAD lamps are designed to project 10,000 lux—a unit of illuminance, or how much light actually hits a surface (rather than how much is produced, like watts). This video discusses product options and practical considerations.

Accessing the dark web is legal in the US, the EU, and most countries worldwide

As long as users do not pay for illegal goods or services or acquire illegal content, they cannot be prosecuted. Those on the dark web include academics, researchers, and cybersecurity experts gathering threat intelligence on cybercriminals, cyberterrorists, and state actors, as well as protesters, activists, and grassroots organizers.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Prediction markets have faced questions about insider trading

While prediction markets encourage bettors to use their knowledge of a situation to inform their trades, these platforms have faced questions about when this borders on insider trading. For instance, traders on Kalshi can bet on who Taylor Swift's bridesmaids will be—but some worry that it would be unfair for Taylor Swift herself to earn money on that specific bet.

Synthetic pheromones may protect coral reefs by attracting their predators

Researchers in Australia and Japan have developed these nontoxic chemicals to attract crown-of-thorns starfish, which consume corals that make up the Great Barrier Reef. As of 2026, synthetic pheromones have been shown to be effective in lab trials, and future field trials will attempt to lure starfish into areas for mass removal.

In 2025, ByteDance agreed to sell the app's US branch

In 2024, US lawmakers passed a requirement for parent company ByteDance to sell TikTok or face a ban in the country, which the company challenged in court. After several extensions granted by President Trump, ByteDance agreed to sell the company's US branch to a group of US investors, including Oracle, which will oversee the app's security and cloud computing.

A Bay Area lab was supplying MLB players with steroids

The Bay Area Laboratory Co-operative, also known as BALCO, began as a modest vitamin shop, but by the 1990s it was at the center of a doping scheme that rocked Major League Baseball and other professional sports.

Peloton paid a $19M fine for its handling of treadmill injuries

In 2021, a six-year-old died after getting caught underneath a Peloton treadmill. A federal investigation into the company revealed that Peloton knew about injuries on the treadmill as early as 2018 and failed to report the incidents to the US Consumer Product Safety Commission.

Baz Luhrmann's 'Everybody's Free (to Wear Sunscreen)' is based on a fake graduation speech

The 1997 song, which was a chart-topping hit in Australia and appeared on the Billboard "Hot 100" in the US, is based on a fake commencement speech written by Chicago Tribune columnist Mary Schmich. For a time, many people erroneously believed Kurt Vonnegut gave the speech at MIT's graduation ceremony.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

TerraUSD offers a cautionary tale of stablecoin use

This stablecoin was completely wiped out in May 2022, losing investors roughly $40B in value, when its linked support token, LUNA, collapsed in value, triggering a spiral that wiped out the dollar peg and left both tokens essentially worthless within days. TerraUSD's creator was sentenced to 15 years in prison in 2025. (Some users may experience a paywall.)

Particles found in Martian air pose significant risks to human lungs

Ultrafine dust, just 3 micrometers wide, is small enough to bypass lung defenses and enter the bloodstream, where its highly reactive chemicals can cause thyroid disease. Silica in the dust can also cause silicosis, a chronic and incurable lung disease.

Dorothy's famous entrance into Oz in 'The Wizard of Oz' relied on analog tricks, including a body double and sepia-toned paint, as much as it did on technology

Massive blooms of microscopic plankton called dinoflagellates produce the neon blue light seen in glowing tides.

'Saturday Night Fever,' the 1977 film that introduced disco to the mainstream, was based on a fabricated magazine story.

Tattoos remain visible on your skin thanks to immune cells called macrophages

Firework or sparkler burns, even if they cover a relatively small area of skin, can significantly affect our range of motion.

Poison ivy was sent to Europe in the 1600s as an exotic, ornamental oddity, where it was purposefully grown in the English royal gardens at Kew, the Faculty of Medicine in Paris, and a few other locations.

Children are now three times more likely to say they want to be a YouTuber when they grow up than an astronaut, with some even attending 'YouTube camps' that teach kids how to create content for the platform.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

Up to a million Girl Scouts sell about 200 million cookie boxes every spring, generating $800 million, largely because refusing a child is frowned upon

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Prince's sexually explicit 1984 track 'Darling Nikki' attracted the ire of the Parents Music Resource Center, an advocacy group that inspired the Parental Advisory sticker, even though the song ends with a Christian message.

The Beatles' US label rejected the band's first two singles, 'Please Please Me' and 'From Me to You,' with one executive calling the band 'dead in the water.'

Domino's Pizza's 30-minute delivery guarantee was responsible for the chain's 1980s surge, but it was discontinued after the company was found liable for delivery driver accidents.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

Lesser-known phobias include turophobia, or the fear of cheese, and nomophobia, the fear of being without your cell phone.

One of the most famous portraits ever taken is 'Afghan Girl' (1984) by Steve McCurry, yet the subject Sharbat Gula went much of her life without being identified or benefitting from the image's success.

While the first exchange-traded fund (a 'basket' of different assets that can be bought and sold on a stock exchange) in the US only launched in 1993, the global ETF market has grown to more than $10T in the short time since.