Ammonium may be the sixth basic taste

Fat is proposed as a candidate sixth basic taste

Oleogustus is Latin for "a taste for fat," and researchers proposed in 2015 that it should be accepted as the sixth basic taste. This article teases apart exactly what it would take to officially be considered the sixth taste and why researchers think the fat taste may be a strong candidate.

How science came to understand umami

Before Dr. Kikunae Ikeda sat down in 1907 and pondered the taste of dashi, scientists typically agreed upon four types of taste: sweet, salty, bitter, and sour. He boiled 90 pounds of kelp into a resin that he then stripped of different compounds until he was left with a single ounce of brown crystals. Testing later revealed these crystals were glutamate, an amino acid and one of the protein's building blocks.

The research that led to sour

Scientists are trying to figure out if there are unique receptors that respond to the molecules that make up flavors we associate with calcium, blood, batteries, and other items that often escape dinner menus. Taste researcher Dr. Danielle Reed says the minimum evidence for a taste category typically involves identifying dedicated receptors and then removing them to show the taste vanishes.

Many parts of the body, including the testicles, have bitter, sweet, and umami receptors

Taste receptors—the tiny cells that report the chemical makeup of external stimuli to the brain—in the testicles don't "taste" in the same way as the gustatory ones you use to determine if there's enough sugar in your tea. Research suggests that these "teste" receptors can sense bitter, sweet, and umami compounds and use that chemical input to control physiological processes or (literally) change direction. (Some users may experience a paywall.)

Monosodium glutamate is a sodium salt form of a naturally occurring amino acid

Monosodium glutamate myths originate from a 1968 letter to the New England Journal of Medicine, in which unpleasant symptoms after eating Chinese food were dubbed Chinese restaurant syndrome without medical data. Subsequent studies show this savory flavor enhancer—found in tomatoes, mushrooms, and other foods—is safe in moderation.

Babies taste food in the womb via amniotic fluid, and it may influence future taste buds

Some estimates suggest that around Week 16 during pregnancy, a growing fetus can begin to taste amniotic fluid that contains flavors in the food that their mother consumed, due to taste bud formation. Scientists think those early flavor experiences may influence future taste preferences. Other scientific resources put that time much later, however—around Week 30.

How bitter taste receptors help guard against infection

Receptors for "bitter" tastes evolved to detect potentially harmful plant chemicals, such as nicotine. The receptors also trigger bacteria-fighting responses, including waving hairlike projections to bat away bacteria, ordering the release of bacteria-killing nitric oxide, and calling for antimicrobial protein reinforcements.

A timeline of the science of taste discoveries

The tongue is made up of four types of papillae—elevated, nipple-like projections that give the organ its rough texture. In the early 1900s, initial research into the tongue's varying taste sensitivity led to a misleading map of the tongue and its taste regions. Over the decades, researchers fleshed out five distinct tastes (and more recently, a sixth).

Aspartame was a surprise discovery from a lab working on gastric ulcers

As with saccharin and cyclamate, the aspartame discovery arose from its discoverer tasting something sweet from his workplace. In 1965, American chemist James Schlatter licked a white powder off his finger as he picked up a piece of paper and was startled to discover it tasted sweet. He applied for a patent for the substance, and received it in 1970. It is now one of the most popular artificial sweeteners. (Some users may experience a paywall.)

The five most common chemicals found in modern food

Most modern processed foods rely on a number of preservatives to stay fresh from production to our plates. The most common include citric acid (preservative and flavor), sodium benzoate (preservative), xanthan gum (thickening and stabilizing), carrageenan (thickening), and red dyes 3 and 4 (for color).

How the methods of catching fish for food affects their taste

Commercially caught fish are often killed through suffocation, allowing the causing the fish extreme stress and flooding their bodies with stress hormones and lactic acid. These chemicals cause the fish's flesh to become bitter where it was once rich and quickens the rotting process.

Read a study documenting how 'old people' smell increases with age

Analysis of body odors from individuals aged 26 to 75 confirmed that 2-nonenal, an unsaturated aldehyde with an unpleasant, greasy, and grassy odor, was detected only in subjects aged 40 and older.

A delicious flavor used to be made from a beaver’s butt

Love vanilla-flavored foods? Well, it was once made from castoreum - a yellowish exudate from the castor sacs of mature beavers. And the FDA regards castoreum as “natural flavoring."

Astronauts agree: The moon smells like gunpowder

Twelve astronauts have walked on the moon to date, and they all agree that our lunar neighbor smells like gunpowder. Scientists argue this scent comes from unstable minerals that cling to their suits and the rocks they return to the ship. Notwithstanding, space itself has a different smell, often compared to steak or metal, which experts believe, rather poetically, is the smell of dead stars.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

The Oktoberfest taste test

Wondering how the different Oktoberfest beers stack up? This article dives into the six official beers you’ll find at the festival. Each one has a write-up that includes a bit of history, tasting notes, and thoughts on where and when you might enjoy drinking it.

Unusually stable, undiscovered elements may exist near atomic number 126

While heavier elements like uranium and plutonium are unstable and decay quickly, simulations suggest a pocket of stability exists for elements with approximately 126 protons and 184 neutrons. Such elements may have practical applications, such as americium, a synthetic element used in smoke detectors.

Typhoid smells like freshly baked brown bread

Certain ailments are associated with documented scents, including diabetes, Parkinson's disease, and typhoid. The skin of people with yellow fever, for example, can smell like a "butcher shop."

Americans spent $6.6 billion on body odor products in 2023

This high figure from Euromonitor, a research firm, suggests Americans spent more on deodorant than in any other country. Beyond deodorant, there's also growing interest in "whole body" deodorant designed to mask smells from various parts of the body beyond the armpit.

Tasting a lab-grown chicken nugget

Taste testing the first clean meat chicken nugget from a San Francisco company developing cultured meat. It’s chicken, but not as you know it.

Salt is harvested from briny ocean water and underground deposits

Mostly sodium chloride, this compound is produced for human use by collecting seawater in shallow pans and allowing the Sun to evaporate the water until crystals remain. Underground rock salt is mined, crushed, and purified from deposits left behind by ancient seas that have dried-up.

A list of five scientific theories that were accepted and later disproved

Humoral theory held that everyone's personality derived from different combinations of four bodily fluids: blood, phlegm, yellow bile, and black bile. The phlogiston theory stated that all combustible materials possessed a fire element—phlogiston—that was released and absorbed by the air during burning. When the air became saturated with phlogiston, the fire would go out.

Researchers generally group gut bacteria into six different categories

The trillions of bacteria in the gut microbiome can be grouped into six categories: firmicutes, actinomycetota, pseudomonadota, fusobacteriota, bacteroides, and a broad miscellaneous category. The functions of each are complex but range from breaking down food and producing vitamins to fighting pathogens.

Nitrogenous bases connect like puzzle pieces due to their shape

There are four bases—adenine, thymine, cytosine, and guanine—which keep the two strands of DNA connected via chemical bonds between them. Connections between thymine and adenine require two hydrogen bonds, while those between cytosine and guanine need three hydrogen bonds. These differences in bond number prevent non-complementary pairings.

Watermelons were once neither red nor sweet

The gargantuan summer picnic staple has a fascinating story: 100 million tons are produced worldwide and they take up the most space of any vegetable crop in the world. But not long ago, the flesh of the melon was white and it had a bitter taste.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

What exactly is dopamine?

Dopamine is a neurotransmitter—a chemical released by neurons that enables neural communication—that makes people want things with an "almost animalistic desire," compelling them to snack or check phone notifications. Often misrepresented as a "pleasure" chemical, dopamine is involved in motivation, learning, attention, habit formation, and more. Trends like dopamine fasting overinflate its role in mental health and often use it as part of "straw man" biohacking claims.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Lesser-known phobias include turophobia, or the fear of cheese, and nomophobia, the fear of being without your cell phone.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

Poison ivy is in the same family as mangoes, cashews, and pistachios—and they all produce oily urushiol in their raw, unprocessed state—but they are typically prepared in ways to avoid causing human discomfort.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Pure water does not conduct electricity because this flow of energy requires the movement of charged particles, and water is a neutral molecule.

See how fireworks are made and learn how metals like magnesium and copper are responsible for different colors.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

A pickleball's loud 'pop' sound can reach 120 decibels, which is equivalent to a hammer hitting a nail

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

The Nasdaq's 'Magnificent 7' companies are responsible for roughly 40% of the Nasdaq 100 index's gains, while the remaining 93 companies account for the other 60%.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

Apollo astronauts left items in the moon's 'toss zone,' including golf balls, family photos, and bags of human waste, to make room for lunar rocks.

Children are now three times more likely to say they want to be a YouTuber when they grow up than an astronaut, with some even attending 'YouTube camps' that teach kids how to create content for the platform.

A small portion of The Winstons' 'Amen, Brother,' an obscure '60s gospel record, is the basis for thousands of hip-hop tracks, making it one of the most sampled records ever that's informally known as 'the Amen break.'

Existentialist writer Jean-Paul Sartre coined the famous phrase 'Hell is—other people' in his play 'No Exit'

The most expensive ad of all time was for Chanel No. 5 perfume and cost roughly $33M to produce in 2004—about $57M in today's dollars.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

Despite being favored by 87% of Americans, Congress does not have term limits.