Read a study documenting how 'old people' smell increases with age

'Old people' smell is real—it's a chemical buildup when fatty acids on the skin oxidize

The chemical composition of body odor seems to change with age. Later in life, we harbor higher concentrations of a chemical compound called 2-nonenal that forms when omega-7 fatty acids on the skin oxidize, and the skin's natural antioxidant defenses weaken. Commonly called "nonenal", it's the smell widely associated with aging, and it's often described as a grassy or greasy odor.

1 in 15 adults over age 40 experience phantom odors

This phenomenon was measured in a 2018 study that examined the prevalence and risk factors for phantom odor perception. Older adults were less likely to experience these phantom odors as they age, just as their overall sense of smell declines. Women are more likely than men to perceive phantom odors.

Carboxylic acids are one reason teens are smelly

Scientists compared the smells of babies and teenagers and identified some of the compounds that make teens smelly. Carboxylic acids present in teens, they wrote, seemed to give off an "earthy, musty, or cheesy" scent. This 2024 research could help inform future odor-control products.

A 2025 study explored the common words to describe body odor across 17 countries

The work identified the 25 most frequent words used to describe body odors across languages, ranked by frequency, and found that "sweaty" topped the list, followed by "sour" and "stinky."

Smell is a robust memory cue for individuals with Alzheimer's disease

Odor is more effective than both visual and verbal cues for triggering autobiographical recall in Alzheimer's disease, according to 2021 research.

Read the academic article explaining how ancient smells can be dissected and recreated

This paper explores how biomolecular data on past scents can be teased out and then transformed into olfactory museum experiences, adding another component to our understanding of archaeology.

How our sense of taste evolves as we age

Kids are hardwired to prefer sweets over greens, with sweetness a shorthand for calorie-rich and bitter flavor warning of potentially noxious plants. This holds true even in the womb, where fetuses have been seen via ultrasound scans grimacing as their hosts consume kale capsules. As they age into double digits and beyond, their taste cells and sense of smell diminish, leading to broader and less sensitive palates.

Humans can't smell the inside of their nose due to olfactory fatigue

Once a person is accustomed to a specific odor, their neurons have trouble continuing to respond to that smell because of that familiarity. That's why humans may not notice when their house smells like trash until they leave the house and then return to it.

Humans may be able to distinguish more than one trillion scents

That's according to one estimate published in 2014. This figure far exceeds earlier estimates of a human smelling ceiling around 10,000 odors. The newer figure is derived from experiments in which volunteers agreed to sniff varying scents. Researchers mixed odor components and had volunteers sniff the brews to detect subtle scent differences. (Some users may experience a paywall.)

Explore the chemistry of undesired body odors

This graphic highlights some of the main compounds in different body odors, including halitosis (bad breath), flatulence, and foot odor.

On average, people smell worse if they're sick

For a small 2014 research study, a panel was tasked with sniffing the smelly t-shirts of people who had been injected with a compound known to activate the immune system and those of controls without the shot. It found that those who were acting as if unwell (due to the injection) generally smelled worse. Subsequent work found that those who sniffed unpleasant odors had a mild immune response of their own—perhaps to protect them from disease. (Some users may experience a paywall.)

Most people with East Asian ancestry are genetically predisposed to be less smelly

A gene variant found in 80%-95% of individuals with East Asian ancestry reduces armpit bacteria and related odors. People with this nonfunctioning ABCC11 gene variant lack a protein that transports molecules, including sweat, across cellular membranes, so their armpits are starved of sweat that bacteria may have metabolized to help them multiply.

Heightened sense of smell during pregnancy is not yet well understood

Boosted smell powers and strong reactions to them are often reported beginning around the six-week mark of pregnancy. Researchers say hormonal changes likely play a role, but the change remains poorly understood.

Perceived isolation ages you

Mounting evidence suggests that socialization is a vital component of maintaining good health. Research published in 2024 from Mayo Clinic researchers analyzed the social lives of more than 280,000 adults and concluded that individuals that weren't likely to participate in extracurricular social activities and get-togethers were more likely to have a biological age older than their actual age—meaning that you may be 60 but health indicators would suggest you're older.

Doctors use three key physical markers to determine biological aging

The length of the ends of chromosomes (known as "telomeres"), the gradual change in collections of DNA molecules called "methyl groups", and the secretion of inflammatory proteins are all used as indicators of biological age.

Odor blockers use nonpolar oils to trap smelly polar molecules

In the case of feces, gut bacteria produce compounds such as skatole and hydrogen sulfide, which the brain registers as unpleasant. Because oils do not dissolve in water, they can be used to create a layer on the surface that prevents smelly compounds underwater from escaping into the air.

Fear has a specific 'smell'—at least to machines

This excerpt from a Mythbusters episode takes on the smell-of-fear question, comparing the sweat composition of individuals exposed to snakes, rats, and scorpions with that of people exercising. Molecularly, the sweats are different to a gas chromatography machine, but to most noses would be indistinguishable.

The Dog Aging Project uses information from over 50,000 dogs to explore longevity

The study gathers health, lifestyle, and genetic data to understand what helps dogs live longer, healthier lives. Findings could also provide human health insights due to our shared surroundings and biology.

One decibel of hearing loss increases tinnitus risk by 6% for older people

That's according to an analysis of more than 18,000 people published in BMC Medicine in 2023. The tinnitus risk is not just limited to older people: The research also concluded that one decibel of hearing loss increases the risk of developing tinnitus among young adults by 3 percent.

Why your wine smells unpleasant

Ever had the experience of receiving a bottle of wine with a janky, less-than-favorable odor? This Esquire article ventures to answer this question and offers the explanation that the culprit is likely corked wine. Read to understand why corks can create a moldy or musty scent, and feel emboldened to send a corked bottle back for something with improved quality.

Less than 1% of aging studies consider menopause and its effects

Nearly all studies researching the biology of aging don't consider menopause in their setup, in part because menopause is difficult to emulate in animal models. Menopause is uncommon in the animal world beyond humans and whales. This presents a problem for medicine and science because about 75% of aging-related diseases are likely influenced by menopause.

Review the health effects of living near oil refineries, including increased respiratory risks

An analysis of 54 studies published between 1977 and 2024 in 15 international regions found evidence that proximity to refineries increased the risks of leukemia, asthma, bronchitis, and respiratory symptoms. Several studies also identified worse cardiovascular function in children and adults living near refineries, alongside other acute and chronic health impacts.

The "reminiscence bump" causes memories from adolescence to last

Research shows that the "reminiscence bump" phenomenon, which applies to memories formed between the ages of 10 and 30, contributes to songs from those ages triggering the most intense nostalgia. This may be due to biological and hormonal changes enhancing memory effectiveness during adolescence.

Face and neck massages improve the removal of brain cell waste products in mice

A study identified that massaging mice and monkeys' faces and necks enhanced the flow of cerebrospinal fluid. Because CSF has been shown to flush out proteins linked to Alzheimer's and Parkinson's, the research hints at non-invasive treatments to reduce the severity of these diseases.

Neanderthals commonly had surfer's ear, a potential sign of extensive seafood collection

Analysis from 2019 found that about half of the 23 Neanderthal skulls scientists examined seemed to have the bony growths in the inner ear, signifying they had surfer's ear. Those growths suggest our ancient relatives, dating back to between perhaps 100,000 and 40,000 years ago, were potentially hunting fish, mollusks, or other marine resources in chilly waters.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Urushiol, the oily toxin in poison ivy, can remain allergenic on clothing for years.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

The most expensive ad of all time was for Chanel No. 5 perfume and cost roughly $33M to produce in 2004—about $57M in today's dollars.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Some researchers have labeled nomophobia, the fear of being without your phone, as 'the phobia of the 21st century.'

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

In 2026, Finland was named the world's happiest country for the ninth consecutive year based on its wealth, social safety network, and high life expectancy, among other factors.

20,000 letters to the advice columnist 'Dear Abby' provide insight into prevailing sex, religion, and LGBTQ fears, anxieties, and concerns from the 1950s onward.

Crows are believed to have intelligence on par with a seven-year-old child and demonstrate complex behaviors, from problem-solving with tools to recognizing human faces.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

US housing costs have risen by roughly 175% between 1991 and 2026—but a growing number of Gen Zers are becoming homeowners anyway. In 2025, 4% of homebuyers were Gen Z, up from 3% the year before.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Prince's sexually explicit 1984 track 'Darling Nikki' attracted the ire of the Parents Music Resource Center, an advocacy group that inspired the Parental Advisory sticker, even though the song ends with a Christian message.

Learn how to read a prospectus, the juicy document that any company must file with the SEC before going public.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

A pickleball's loud 'pop' sound can reach 120 decibels, which is equivalent to a hammer hitting a nail