Watch this video letter (via Facebook) from a kidney recipient to his donor

Read why one man agreed to get a pig kidney in 2025 to replace his own failing organ

The 68-year-old New Hampshire man told USA Today that a motivator for the experimental surgery was his belief that he was going to die anyway, and other people suffering from kidney disease could gain valuable insights. Yet the surgery bought him time—he lived 271 days with a pig organ and later received a human kidney transplant. Clinical trials began in 2026 to test the pig xenotransplants in more people.

The first successful organ transplant was performed in 1954

The successful kidney transplant procedure, at what's now-called Brigham and and Women's Hospital, ushered in a new medical era and gave hope to patients with organ failure. The recipient, 23-year-old Richard Herrick, lived eight more years after receiving the donated organ from his living twin brother, Ronald.

Living donations most commonly involve a kidney or part of a liver

In 2023, more than 6,900 transplants were made possible thanks to living donors. Living donation is when a living person donates an organ or part of an organ—usually one of their two kidneys or part of the liver, since that organ can regenerate in a healthy person. Much more rarely, living donors donate other organs. Living donations often occur when someone wants to ensure a loved one has certainty that they will quickly receive a needed organ.

Thousands of donated human kidneys are thrown away annually

Ten donated kidneys are thrown away daily even though thousands of people are awaiting a kidney transplant. Listen to a kidney doctor and a 2012 economics Nobel laureate discuss why this happens and how the organ transplantation system may be improved. Transplant centers are penalized for low transplant survival rates, they note, and that contributes to why hospitals may decide certain organs are just too risky to use.

You can sign up to donate your organs at this website

A single person who chooses to donate their organs upon death can provide organs for as many as eight people. You can sign up to become an organ donor or update your donation status information at this website, or you can typically sign up at your state's Department of Motor Vehicles. Many states allow individuals to declare which tissues and organs you consent to donate (i.e. organs, eyes, and skin tissue). It's recommended to discuss your decision with your family so they are aware of your wishes.

How heart transplants work

Heart transplants require an old heart to be removed and a new one to be installed without killing the patient. How does that work? In this easy-to-understand five-minute video, learn each step of the intricate process, from donor matching to the preservative solution a heart is doused in while it is transported.

NSF-funded research into matching algorithms improved the success of organ transplants

Investigations in game theory, including concepts focused on creating mutually beneficial partnerships—matching theory—led to the design of computer systems that efficiently matched kidney recipients and live donors, resulting in higher-quality matches. By 2019, these matching algorithms were used for multi-organ exchanges.

How personalized gene-editing saved a baby's life

KJ Muldoon had a 50% chance of surviving a genetic mutation until doctors developed a one-of-a-kind gene-editing therapy. In an interview with one of the researchers behind the treatment, learn what it will take to make personalized genetic medicine possible for everyone.

Watch patient stories describing life with macular degeneration

This video series features patients discussing their experiences with the disorder, family members describing caregiving, and other insights about the disease.

Stranger pays for a family's breakfast tab and writes heartfelt note praising the father of three kids

In Fort Worth, Texas, an Emergency Room doctor wearing scrubs was enjoying a meal with his wife and three children. While getting ready to pay, the family learned that their $85 bill had already been settled, with a kind note left behind. The message was signed by "a retired Army Medic" who thanks the man for being a good father.

An avowed rationalist discusses his near-death experience

Documentarian Sebastian Junger, a veteran reporter and skeptic discusses his experiences—in particular, a frightening vision—after an aneurysm and internal hemorrhaging left him nearly dead. Junger talks about his NDE, the possible scientific explanations, and how that day changed his fundamental worldview.

Read Mark Zuckerberg and Priscilla Chan Zuckerberg's $45B letter to their daughter

After giving birth to their daughter, the Zuckerbergs launched the Chan Zuckerberg Initiative in 2015. The pair announced the charitable organization's creation in a letter addressed to their daughter. The Zuckerbergs pledged 99% of their earnings from Facebook over the course of their lives to advance education, cure disease, and transform public policy, something the letter says is a commitment to their daughter's future. The organization has since shifted its focus to artificial intelligence and science.

Turning a profit with terminal illness

After Amanda Riley was diagnosed with cancer, her social media followers rallied to raise funds to ensure their favorite religious influencer could afford one miracle after another. As more than $100,000 of donations poured in, Riley shared glimpses into her health struggles, posting evidence as fake as her diagnosis. Pulling from years of journalistic investigation, this eight-episode podcast series dives into Riley's reality.

This Indiana medical school encouraged students to get to know their cadavers' families

The school's anatomy professor instructed medical students to think of the cadavers they worked with as their "first patients"—using their names to acknowledge that this was a person and to exchange letters with the cadaver's family members if they agreed to participate. At the conclusion of the course, families were invited to a lab-based memorial service.

An essay exploring how living day-to-day with a brain implant helps restore a sense of identity

Companies like Neuralink are experimenting with volunteers who have lost control over their bodies. Many of the program's participants claim the most significant benefit from the tool is the ability to perform simple, mundane tasks, such as playing video games or shaking hands, rather than more obvious milestones like walking or eating. This essay explores what it's like, day to day, to use a brain implant.

USA Today asked readers about their grief—and received more than 700 responses

The submissions included one moving story of two women whose sons died by drug overdose. The duo wrote that they found each other in a support group and decided to navigate their respective difficult situations by starting a podcast together called "Two Moms with Two Dead Kids," which focused on what life was like in the years following the deaths of their children.

Social support plays a critical role in recovery from addiction

This engaging TEDx talk from addiction researcher Jacki Hillios explores addiction recovery through a transformative lens and Phoenix Multisport—an innovative program helping people rebuild their lives through active lifestyles. By living out its core message that people are not defined by their disease, the program demonstrates the power of social support in recovery.

The legacy of America's most remarkable kid

The short life and legacy of Kevin Cooper, a 14-year-old entrepreneur from Utah with big dreams for his family and rural America, and whose accomplishments most adults don’t pull off in a lifetime.

Listen to Dr. Martin Luther King Jr. read his famous Letter from Birmingham Jail

Written in 1963 while jailed for nonviolent protest, Dr. King’s letter defends civil disobedience, rejects calls for patience, and argues that unjust laws must be confronted to expose injustice and force meaningful change.

Amazon sends its first-ever letter to shareholders every year

The first letter to Amazon’s shareholders, written by founder and then-CEO Jeff Bezos in 1997, is a key part of the Amazon story—laying out the company’s long-term approach to the business and several of its core operating values. Bezos emphasizes, for example, Amazon’s plan to start with a bookstore but to evolve into a much larger ecosystem.

An 87-year-old widower goes viral for hand-delivering party invitations door to door that read "4 pm until the cops arrive"

A man knocked on his neighbor's door to offer a paper invitation to a winter-themed party he was throwing. "My wife is gone now, so it gives me something to keep me busy," he later explained. "I'm going to get these people in one room, and maybe they'll get to know each other." The viral experience has since brought him fan mail and party treats.

'Our greatest responsibility is to be good ancestors.'

- Polio vaccine developer Jonas Salk (1914–1995)

Toddler delivers tear-jerking speech at her mom and dad's wedding

Three-year-old Evie brought her father to tears while sharing loving words before her mother walked down the aisle.

Stephen Hawking's final message

Famous cosmologist Stephen Hawking—who lived for half a century after being diagnosed with Lou Gehrig's disease—delivered a final speech just before he died in 2018. In the video, Hawking talks about the importance of science and reason in...

Hear Pearl Harbor survivors reflect on the attack 80 years later

This anniversary video features some of the last living witnesses to the Pearl Harbor attack. Their firsthand memories—shared eight decades later—offer a rare perspective on the day that changed their lives and the world.

Watch what the Ebola virus does inside our cells and organs in order to spread and survive.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

Watch this video that uses Lego bricks to explain how venture capital works.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Children are now three times more likely to say they want to be a YouTuber when they grow up than an astronaut, with some even attending 'YouTube camps' that teach kids how to create content for the platform.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

The Ramones' 'Pet Sematary,' the theme song for the Stephen King novel of the same name, was written while the band was admiring the writer's collection of horror memorabilia.

After NASA's Voyager 1 captured Earth as a single pixel as it left the solar system in 1990, astronomer Carl Sagan used the image to reflect on humanity's fragility and the responsibility to protect 'the only world we've ever known.'

Watch how algorithms can be designed to train themselves and self-improve without human input, to the point where the optimized code is too complex for programmers to understand.

Prince's sexually explicit 1984 track 'Darling Nikki' attracted the ire of the Parents Music Resource Center, an advocacy group that inspired the Parental Advisory sticker, even though the song ends with a Christian message.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

Hear about the 250-year history of the United States Postal Service, complete with some of its strangest deliveries, important innovations, and the figures that made it an American institution.

Meet the 56 signers of the Declaration of Independence—most of whom didn't put pen to paper until August 2, 1776—and see their original signatures.

Take a 3D tour of the Hajj, Islam's annual pilgrimage to Mecca, undertaken by over 1.5 million Muslims.

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls

Legendary architect Frank Lloyd Wright designed the SC Johnson headquarters in Wisconsin, aiming to make a cathedral-like workplace