You can sign up to donate your organs at this website

In the US, you must actively sign up to donate your organs

The US has an opt-in donation system for organ donation—meaning people must provide consent to proceed with any donation. Locations including Spain, the United Kingdom, and Argentina have an opt-out donation system, which means individuals are presumed to be donors unless they actively refuse consent.

Organ donation isn't usually logistically possible if you die at home

Since organs need to be well-preserved for organ donation, with oxygen flowing through the body, internal organs often aren't viable for organ donation if someone dies at home. But some tissues—like eye corneas and skin tissue—may still be donated since they remain usable for a longer period without oxygen flow.

You can sign up to donate your body to science

It's a separate process to donate your body for medical research; you usually must contact a whole-body donation program directly. Bodies can be donated for medical research, for forensic analysis research, or for medical students to work with as they learn anatomy and surgery, among other purposes. Learn more about numerous accredited organizations that provide human bodies, organs, and tissues to medical researchers and students.

'Donation after circulatory death' is on the rise

This occurs when a patient in a coma is on life support and family members agree to donate the organs. Watch this video about a 2025 New York Times investigation that identified 12 instances across nine states of bungled or premature attempts to retrieve organs from people whose families had authorized withdrawal of life support.

Brain death is a top source of organ donation

Brain death is a significant source of organ donations—approximately 40% of organs in the US and the UK are recovered from people who experience brain death. Patients declared brain dead and hooked up to intensive care unit machines will still have oxygen flowing to organs like the heart, lungs, and kidneys—preserving those organs.

Living donations most commonly involve a kidney or part of a liver

In 2023, more than 6,900 transplants were made possible thanks to living donors. Living donation is when a living person donates an organ or part of an organ—usually one of their two kidneys or part of the liver, since that organ can regenerate in a healthy person. Much more rarely, living donors donate other organs. Living donations often occur when someone wants to ensure a loved one has certainty that they will quickly receive a needed organ.

Several years after the English law changed, organ donation rates haven't improved

A 2024 analysis found that several years after England changed its organ donation system to an opt-out donation system there was no improvement to the country's organ donation rates, perhaps highlighting the need for better understanding and education around the law.

UNOS oversees the entire US organ donation system

The United Network for Organ Sharing is a private, nonprofit organization that manages much of the US organ donation and transplantation system under a federal contract. Medical urgency, blood type, organ size, and geography of the donor and recipient are all factors determining how someone who needs an organ is matched with someone who donated an organ.

3 US maps illustrate transplants, donors, and organ waitlist additions—by state

National UNOS tracking data feeds into these US maps that record all the transplants, donors, and waitlist additions in the last 12 months. California, for example, had the most transplantations in 2025—totaling about 5,200—but it also has the longest waiting list, with more than 20,000 additions in that same period.

Donated hearts remain viable three times longer now with new tech

Advances in organ perfusion systems have significantly lengthened the amount of time donated hearts can remain viable for transplant, expanding the possibilities for donor organs to wider geographic areas. "Heart in a box" devices, developed in recent years, enable effective oxygen flow in the donor heart during transport, which means that hearts can now travel farther to potential recipients and still be in good condition.

Artificial intelligence may improve organ donation systems—and even organ health

Mayo Clinic transplant experts suggest that artificial intelligence could potentially improve organ donation systems in several ways, including better identifying patients most at risk for organ rejection, enhancing donor-recipient matching, and helping to avoid organ transplant needs by identifying health issues earlier.

Thousands of donated human kidneys are thrown away annually

Ten donated kidneys are thrown away daily even though thousands of people are awaiting a kidney transplant. Listen to a kidney doctor and a 2012 economics Nobel laureate discuss why this happens and how the organ transplantation system may be improved. Transplant centers are penalized for low transplant survival rates, they note, and that contributes to why hospitals may decide certain organs are just too risky to use.

More than 40 states have passed versions of the Uniform Declaration of Death Act

The 1981 model law, now enacted in most states, is the legal basis for death in the US. There have been many efforts to amend this law, citing the need for more transparency to improve trust between families and the medical profession, though none have moved forward. Alterations to the law could have implications for organ donations and removing life support.

Theoretically, you could lose a bunch of your organs and still survive

If surgeons removed organs including one of your lungs, a kidney, your spleen, appendix, tonsils, part of your liver, and even some of your reproductive organs you could still survive. Watch this animated video which dives into the organs you could conceivably live without.

Watch this video letter (via Facebook) from a kidney recipient to his donor

A kidney recipient named Justin reads a letter he wrote to his deceased donor about how the person's generous kidney donation saved his parents from having to watch him suffer and his brother from having the pressure of perhaps being his only shot at a life-saving transplant.

Gifting money is one way to avoid death taxes

Gifting money while you're alive is one way people avoid estate and inheritance taxes. There is a yearly cap on how much you can give to a person before that money is taxed—but there isn't a cap on how many people you can give money to in a year.

How much your blood really costs

In the US, donating plasma twice a week can earn you $400 a month. But this system only works by targeting people who need the money most. Plasma clinics are placed in low-income zip codes, and frequent donation may increase health risks.

About 70% of the Human Genome Project's reference genome came from one donor

Volunteers who donated blood to the Human Genome Project consented to using no more than 10% of their DNA, raising questions about the project's legality. Listen to how pressure from a private competitor may have driven officials to ignore ethical standards.

Cells can last in the human body from days to a person's entire life

Despite claims that a person's body replaces itself every seven to 10 years, the rate at which cells die and are replaced varies by cell type. Gastrointestinal cells that line the digestive tract and stomach last only a few days, while some heart muscle cells and most neurons are around from birth until death.

Estate planning involves organizing your financial documents—and making sure your family knows where to find them

This article offers tips for keeping yourself organized, such as the list of documents your family may need and suggestions for where to keep the files, both digital and physical.

How humans digest food

Every day, the average human eats close to six pounds of food—all of which must be processed by the digestive system. Ten organs collaborate to transform food that the mouth chews into the energy needed to stay alive. (Stretched out, these organs...

USA Today asked readers about their grief—and received more than 700 responses

The submissions included one moving story of two women whose sons died by drug overdose. The duo wrote that they found each other in a support group and decided to navigate their respective difficult situations by starting a podcast together called "Two Moms with Two Dead Kids," which focused on what life was like in the years following the deaths of their children.

Life insurance offers peace of mind, ensuring that loved ones are financially supported after one's passing

People typically apply for life insurance policies through specific companies or online marketplaces. This video offers more information that's important to know when considering buying life insurance.

Helping support others in older age linked to longer life

Analysis of findings from a long-term study of older couples first interviewed in 1987 and then followed for the next five years found that individuals who lend support to friends, neighbors, and relatives live longer. Non-helpers were more than twice as likely to die as helpers during the five-year period. That's even after controlling for factors including age, gender, and physical and mental health.

Both individuals and businesses can establish trusts

Business trusts can allow trustees to manage a beneficiary’s stake in a business, and more. There are many different specific types of business trusts.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

Calculate how much of your tax dollars go to each federal program based on your income, filing status, and number of children

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

44% of Americans say they pray at least once a day—discover how your state's religiosity stacks up against the rest of the country.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

View the ten deadliest tornadoes in US history.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

The identity of the Tank Man in the iconic photo from the 1989 Tiananmen Square protests remains unknown and was possibly killed.

Art theft is the third-largest source of criminal revenues worldwide, thanks in part to the subjective nature of valuing a work of art.

Domino's Pizza's 30-minute delivery guarantee was responsible for the chain's 1980s surge, but it was discontinued after the company was found liable for delivery driver accidents.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

The first steps to rebuilding your credit score include getting to know exactly what's on your credit report and figuring out how far you are from the '700 club,' or 'good score' range.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.