What a railroad spike through the head taught science about the brain

Everything you know about Phineas Gage is wrong

A stray spark sent a 3.5-foot-long, 1.25-inch thick iron rod through the brain of foreman Phineas Gage in 1848, creating a scientific case that has attracted onlookers for nearly two centuries. His life reportedly soon spiraled out of control, with his behavior tending toward selfishness and chaos. Evidence of these changes is far less common, with Gage's story bloated by fabrication, scientific prejudice, and artistic license.

How a brain injury created a mathematical mind

In 2002, two men savagely attacked Jason Padgett outside a karaoke bar, leaving him with a severe concussion--and turning Padgett into a mathematical genius.

The impact of gravitational force on our bodies surprised early coaster riders and engineers

There is only a certain amount of gravitational force that the body can handle before dealing with consequences like short-term vision loss or unconsciousness. Increased scientific understanding has largely reduced these impacts, with engineers combining periods of intense pressure with periods of relief.

Everything scientists could learn by looking at your skull

Our skulls are all unique, but they also share characteristics across groups of people. In the absence of fingerprints, forensic scientists can learn a lot about you just from your skull.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

The brain doesn't seem to massively rewire following amputation—upending earlier beliefs about phantom pain

The findings, published in 2025, traced three amputees' brain-body maps and how they respond to body part movements—both before and after scheduled arm amputations. The unexpected neural stability suggests that the unchanged pathways for the missing limbs may explain why people continue to feel them so acutely.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

Medical recognition of strokes stretches back to ancient Greece

Every minute, 750 milliliters of blood flows to the brain, supplying 20% of the body’s oxygen. A sudden disruption—whether from a clot (ischemic stroke) or a bleed (hemorrhagic stroke)—can be life-threatening. From ancient Greek theories to modern CT and MRI scans, here’s how stroke science has evolved over time.

The role of fire in the evolution of humanity's big brains

Roughly 1.5 million years ago, the brain size of our hominin ancestors exploded. To understand why, Richard Wrangham posited the cooking hypothesis, arguing the adoption of fire as a means to cook food had a lasting impact on our ability to digest...

A 36-year-old Russian physicist survived a particle accelerator beam to the head

Several safety mechanisms failed during Anatoli Bugorski's inspection of malfunctioning equipment at the U-70 synchrotron, the Soviet Union's largest particle accelerator. Despite receiving as much as 600 times the lethal dose of radiation to the brain, he has shown no intellectual damage and worked until the age of 77.

The history of brainwashing in America

"Brainwashing" refers to a coerced shift in worldview, often associated with cults or oppressive totalitarian governments. Though such processes are not well understood on a neurological level, they hold an outsized role in public imagination, particularly in science fiction and dystopias. This article reviews the history of the term, first popularized by Edward Hunter in 1950, and the subsequent use of the approach in pop psychology, the CIA, and more.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

How alcohol rewires your brain

Alcohol doesn't just make you tipsy—it rewires your brain chemistry in real time. It slows your brain with GABA, spikes dopamine to make you feel unstoppable, and blocks glutamate so you can't form memories. That mix explains everything from slurred speech to blackouts … and brutal hangovers.

Synaptic plasticity allows neurons to communicate effectively and form memories

First proposed in 1949, synaptic plasticity allows the brain to adjust communication strength between neurons. This ability to change synaptic strength—either briefly or over long periods—is essential for learning and memory, with long-term synaptic plasticity forming the basis of how memories are stored.

The Civil War turned the Continental Divide into an American symbol of identity

Historians argue that the boundary only became a celebrated American symbol in the 1860s, when Civil War-era leaders promoted a west-east geographic divide to replace the devastating north-south political divide, and that the term's use spiked after the transcontinental railroad crossed it in 1868.

An avowed rationalist discusses his near-death experience

Documentarian Sebastian Junger, a veteran reporter and skeptic discusses his experiences—in particular, a frightening vision—after an aneurysm and internal hemorrhaging left him nearly dead. Junger talks about his NDE, the possible scientific explanations, and how that day changed his fundamental worldview.

Listen to how the 1902 'poison squad' experiments changed food safety in America

As part of government research, a group of young men were paid to eat standard American food—replete with food additives like borax and formaldehyde—which revealed the dangers of unregulated food. The work was led by the first FDA commissioner, Harvey Wiley, who helped end the "century of the great stomachache."

Shrunken human heads were once a valuable commodity

In the Ecuadoran Amazon of the 1800s, shrunken human heads had spiritual significance. As outsiders became fascinated by the exotic practice, head shrinking became commercialized, and counterfeit shrunken heads were common. By the mid-1940s, shrunken heads could be traded for guns. (Some users may experience a paywall.)

NASCAR’s SAFER barriers help reduce tragedies at races

Following the death of Dale Earnhardt Sr. in 2001, NASCAR changed its culture to be safety-first. Part of its changes were to install barriers along tracks that would help absorb the majority of g-forces in a crash. This Daily Downforce article walks through the history of the SAFER barriers, why NASCAR originally chose concrete, and how much of the tracks are covered today.

A man survived being struck by lightning seven times

Roy Sullivan worked as a park ranger when he was first struck in April 1942 while fleeing a watchtower during a thunderstorm. Nicknamed the "Spark Ranger," he would be struck six more times while driving, in his garden, working in a guardhouse, sitting in his car, walking, and on a fishing trip.

What rodent cars can tell us about human joy

Neuroscientist Kelly Lambert and her colleagues taught rats to drive in a mini car. She writes her findings from this unconventional experiment, sharing that positive and fun experiences can sculpt the brain just as powerfully as stressful ones. Click to learn more about how the apparent joy of these rodents seemed to enhance their neuroplasticity.

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

A rush to invest in British rail in the 1840s led to investor ruin

During “Railway Mania,” speculative excitement pushed British rail shares to extreme valuations as investors chased rapid expansion. When costs ballooned and profits failed to materialize, the bubble collapsed in 1847—wiping out fortunes across the country.

Explaining the physical connection between the gut and brain

This video overview from Duke University helps visualize the gut-brain axis—a physical connection of nerves running from the brain to digestive tract that acts as a physical and chemical link.

A young Basquiat was fascinated by the book 'Gray's Anatomy'

At 7 years old, Basquiat was hit by a car while playing stickball. While in the hospital, his mother gave him a copy of Henry Gray’s medical reference book “Gray’s Anatomy” to help him better understand his recovery. The book fascinated the young Basquiat, who’d later incorporate bodies and anatomy into his art.

John Riddell’s first helmet was adopted by college football teams in 1939

The early days of football were violent and there was little protection for players, especially their heads. When deaths became commonplace, John Riddell set out to invent a better way to protect football players. Eventually, the technology from Riddell’s helmets ended up on WWII battlefields.

Charles Darwin studied goose bumps by scaring zoo animals in London with a stuffed snake

Read the famous naturalist’s work from the late 1800s, detailing how he sought to draw comparisons between how animals and humans respond to fear. As part of that work, he exposed monkeys and a peccary to a stuffed snake and noted the animals’ hair-raising fear response.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

Exploring the Larry Bird punch that almost changed March Madness

In 1915, workers recovered a submarine-like vessel from the Chicago River, prompting fears of German espionage

Abraham Lincoln was almost assassinated weeks before his inauguration as he traveled from Illinois to DC through Baltimore in 1861; it took two independent claims for Lincoln to be convinced the threat was real

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

See how fireworks are made and learn how metals like magnesium and copper are responsible for different colors.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

Hear about the 250-year history of the United States Postal Service, complete with some of its strangest deliveries, important innovations, and the figures that made it an American institution.

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

Scientists testing how climate change affects plants found, in a years-long simulation study, that poison ivy grew 70% faster with the resulting extra carbon dioxide.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

The 19th-century painters of the Hudson River School were among the first American romantics, with portraits that displayed the natural beauty of the young country.

Stanford built a Google Maps for the Roman Empire, revealing how much it cost to travel in the ancient world