The invention of cheese likely came from a fruit fly landing in a pail of fermenting milk

Microbes are essential to creating the many varieties of cheese, influencing texture and taste

Microbes break down proteins and fats and produce compounds with distinct tastes. These microbes can include bacteria (like the one used to give Swiss its trademark holes), molds (like the ones that give blue cheese its distinctive veining), and countless other tiny organisms.

Ancient Romans helped develop modern cheese production techniques

The ancient Romans loved cheese and experimented with different processes to elevate its flavor, like aging. Some of their innovations, like Pecorino Romano, you can still find today. Others, like the smoked goat-milk Caseus, we only know about through historical records.

Animals' stomach lining produces cheese

Cheesemaking would be impossible without rennet, the enzyme that separates milk’s liquid and solid components. Rennet occurs naturally in the stomach lining of young goats, cows, and lambs to help them digest milk, a process that also allows cheesemakers to use it to make curds. Now we have plant-based rennet that comes from thistles, artichokes, and other similar plants.

A New York farmer established the first cheese factory and revolutionized the industry

Jesse Williams, a farmer in New York state, had a passion for cheese but didn’t have the resources to produce it at the scale he desired. So, in 1851, Jesse and his son opened the first cheese factory, sourcing milk from multiple local farms and producing 100,000 pounds of cheddar—in their first season. Soon, Williams had hundreds of factories and created the prototype for cheesemaking as we know it today.

The world's most unique cheeses

Some are set apart by their unusual ingredients, like moose milk or live mites. Others are defined by texture, like the Georgian specialty tenili, a very rare hand-pulled cheese that resembles yarn or pasta strands. There’s even a canned cheese that has been using the same strain of bacteria for more than 70 years.

Research on bacterial cultures used in yogurt production led to CRISPR's discovery

Scientists learned it was a microbial immune system that could be repurposed to protect dairy cultures from viruses. Today, nearly all yogurt is made with CRISPRized bacteria, as are genetically modified crops like herbicide-resistant corn, wheat, and soy.

There are 6 essential steps in cheesemaking

The six basic steps that are required to turn milk into cheese start with acidification and end with ripening (aka aging). This guide explains what happens at each step and how it contributes to the finished product.

Cheese is a less-well-known Hanukkah culinary tradition

It comes from a story of Judith, a widow whose hometown of Bethulia in Israel was seized by the Assyrian king Nebuchadnezzar. In some iterations, Judith brought the king's general, Holofernes, an array of salty snacks, including cheese, leading him to drink enough wine to pass out. Judith then beheaded Holofernes, inspiring the Israelites to attack and win the battle.

Globalization is increasing the demand for cheese

The increased popularity of Western cuisine has affected the cheese market in historically cheese-averse regions like East Asia. Japan has gotten particularly excited about exploring what cheese has to offer, with festivals and creative fusion dishes featuring the versatile ingredient.

Why some people say the moon is made of cheese

Mental Floss digs into the history behind the fable, which dates back as far as the 1500s, when it was mentioned in "The Proverbs of John Heywood." Even NASA has gotten in on the joke, tweeting a (supposedly) doctored photograph showing the moon's expiration date.

An interactive periodic table maps every possible combination of cheese variables

Plotting milk type, texture, rind, mold, aging, and processing as intersecting axes, the tool shows which combinations already exist as named cheeses, which survive only as rare regional styles, and which remain entirely unexplored.

Researchers believe beer was being brewed 13,000 years ago

In 2018, archaeologists discovered traces of a wheat-and-barley-based alcoholic beverage near Haifa, in modern-day Israel, and believe it was produced by the Natufian people.

What we know about aurochs, the ancestors of modern cattle

The relationship between humans and cattle is invaluable and longstanding. Evidence suggests cattle's wild, larger, and now-extinct ancestors, the aurochs, were also linked to early humans. Similarly valuable for their milk and labor power, yet significantly more threatening due to their size, aggression, and speed, auroch domestication was slow and complex. Discover new information about the fascinating ancestors of modern cows and the potential of re-introducing the species with selective breeding.

Why Pabst Blue Ribbon switched from brewing beer to making cheese during Prohibition

The brewer marketed its product, Pabst-ett, as "whole milk cheese food," available in both block and spreadable forms, as well as various flavors.

Penicillin was discovered by accident

In 1928, Alexander Fleming returned from vacation to find mold contaminating a petri dish of bacteria. Around the mold, the microbes had died—an accidental observation that led to the discovery of penicillin.

Measles evolved from an ancient cattle disease as early as 3,000 years ago

Genetic analysis suggests that the closest modern relative of measles is a livestock virus known as rinderpest, with the viral strains diverging between 2,000 and 3,000 years ago. The timing coincided with the rise of major cities above 250,000 people, offering a novel transmission route for the newly mutated measles virus.

Bees evolved from meat-eating wasps that became vegetarian

After flowering plants first appeared approximately 140 million years ago, some wasp diets would have changed as they consumed pollen-coated insects that would visit these plants. Bees that branched from these wasp species also developed long tongues to slurp nectar and ultraviolet vision to identify flower patterns unseen by humans.

Wine explained

Wine is the sublime product of fermentation, the process of breaking down fruit—typically grapes. As the grapes ferment, yeast consumes the natural sugars and converts them to alcohol. With the process first developed and refined thousands of years ago, wine has been a central feature of celebrations throughout modern history. Want to learn more about its origins? Check out 1440's explainer on wine.

Before discovering cells, life was believed to emerge suddenly from inorganic matter

Popularized by Aristotle in the 4th century BCE, spontaneous generation was used to explain phenomena like mice appearing in seemingly sealed grain storage. The invention of the compound microscope in the late 16th century led to the identification of cells as the basic unit of life, but it was not until 1855 that their origin from preexisting cells was established.

Ancient Greece originated roughly 4,000 years ago around the Aegean Sea

From architectural feats to the Western alphabet, ancient Greece has helped shape modern life. Over centuries, the eastern Mediterranean culture grew as far as India, Egypt, and Spain. Its cultural influence has long since spread beyond any physical boundaries.

Tracing the history of refrigeration

Refrigeration has become critical to most of our lives. But not long ago, it wasn't available. How did we become so dependent on our fridges and freezers? This fun, informative podcast traces the history of keeping it cool with ice and...

Kulfi, an ice cream predecessor, dates back to the 16th century

Historians believe India’s royal court began freezing condensed milk, pistachios, and saffron in conical molds to create the sweet treat. Today, it’s often served on a stick and covered with chopped pistachios.

See a timeline of landmark discoveries in the field of genetics

From the first genetic map of fruit fly genes in 1911 through the completion of the Human Genome Project in 2003, scientists have built upon each other's discoveries to further our knowledge of the human body and the genetic instructions that inform our traits and disease risks.

Lactose intolerance is not the same as a dairy allergy

Lactose intolerance can develop in adulthood and can be influenced by genetic factors, culture, and dietary practices. Times of famine may have favored those who could digest dairy, naturally selecting them more, resulting in lactase persistence.

How science came to understand umami

Before Dr. Kikunae Ikeda sat down in 1907 and pondered the taste of dashi, scientists typically agreed upon four types of taste: sweet, salty, bitter, and sour. He boiled 90 pounds of kelp into a resin that he then stripped of different compounds until he was left with a single ounce of brown crystals. Testing later revealed these crystals were glutamate, an amino acid and one of the protein's building blocks.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

Learn more about the history of fireworks, which dates back to an accidental invention during an alchemist's quest for information about immortality.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Scientists can determine Earth's past climate conditions by analyzing air trapped in microscopic bubbles within ice cores—columns of compressed snow layers that build up over hundreds of thousands of years.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Lesser-known phobias include turophobia, or the fear of cheese, and nomophobia, the fear of being without your cell phone.

Poison ivy is in the same family as mangoes, cashews, and pistachios—and they all produce oily urushiol in their raw, unprocessed state—but they are typically prepared in ways to avoid causing human discomfort.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

A researcher recently discovered an interview from 1967 between groundbreaking journalist Joan Didion and the Grateful Dead, years before the band became an institution.

The Brothers Grimm were lawyers before they were storytellers, but became interested in fairy tales as they began investigating how rules and customs had been passed down through cultures.

One disco producer saw 'Star Wars' four times on its opening weekend and was so inspired that he recorded the album 'Star Wars and Other Intergalactic Funk,' which produced a chart-topping single.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

See photos of Meteora, a mountainous site in central Greece, home to 14th-century monasteries perched atop soaring outcroppings.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight