The history of ectogenesis and artificial wombs

The science and ethics of artificial wombs

Artificial wombs may be able to help preterm babies survive their early entry into the world and possibly curb the long-term adverse health effects associated with such premature birth. This article dives into the current ethics and science behind artificial wombs and ectogenesis, which is when a fetus develops in artificial conditions.

Scientists first observed a sperm and an egg uniting in 1876

Throughout human history, scholars and researchers have speculated on the origin of human reproduction. It wasn't until the late-19th century that the physical process of egg fertilization via sperm cells was observed (in sea urchins), forming the basis for modern fertility research.

The first successful IVF pregnancy was in the United Kingdom in 1978

Gynecologist Patrick Steptoe and his collaborator Robert Edwards, a biologist, attempted to fertilize a human egg cell in a petri dish 101 times before finally succeeding. This resulted in the birth of Louise Brown—at the time referred to as a "test tube" baby—in 1978, who was born into the spotlight.

IVF was long considered controversial and ethically dubious

In spite of its wide acceptance as a form of reproductive assistance today, and its role in helping millions of people have children, in vitro fertilization was once considered a controversial threat to society. One magazine went as far as to describe the procedure as "the biggest threat since the atom bomb."

In vitro gametogenesis: using induced stem cells to fertilize eggs

Using stem cells from skin and mouth cells could save hopeful parents time and money and spare egg donors from significant amounts of discomfort throughout the process. There are potential consequences, not just for infertility treatment, but for the ability to create customized cells of any type.

The origin of cyborgs

The term "cyborg" was coined in a 1960 academic paper discussing what alterations humans would need to undergo to survive in extraterrestrial environments, a venture far "more logical than providing an earthly environment" in space. According to authors Manfred E. Clynes and Nathan S. Kline, Cyborgs with a capital C have incorporated exogenous components that extend their ability to adapt to new environments. Read the paper here.

Read the 1963 study testing out an ancient Egyptian pregnancy urine test

The study sought to test out the ancient Egyptian approach of having a woman urinate on barley and wheat seeds to ascertain pregnancy status. Surprisingly, the research concluded that pregnant women's urine did promote growth of cereal grains the majority of the time; nonpregnant women's urine did not. Unfortunately, the sex of the child could not be accurately predicted based on which crop grew.

An 18th-century woman tricked doctors into believing she gave birth to rabbits

Mary Toft was a poor servant in Surrey who reportedly sought fame and money by perpetuating the story of her "monstrous birth." After having a miscarriage a month earlier, Toft claimed to still be pregnant and called obstetrician John Howard to witness her give birth to animal parts, including a cat without a liver, a rabbit’s head, the legs of a cat, and nine dead baby rabbits. Eventually, after fooling the court physicians of King George I, she confessed to orchestrating the births.

Humans have speculated about alien life since ancient times

Around 50 B.C.E., Roman poet and philosopher Lucretius shared the idea that alien life was possible, which was put forth by Greek philosopher Epicurus. The writing is believed to be the first straightforward assertion in Western literature that aliens must exist.

Why humans evolved single-child pregnancies

While birthing twins has been a rare occurrence for humans, research suggests that twins were actually the norm much further back in primate evolution. It’s proposed that single-childbearing turned out to be critical for the evolution of larger babies with larger heads. Discover more about the shift that gives insight into primate evolution.

Biotech is trying to boost drug production efficiency—using chicken eggs

A company called Neion Bio is genetically engineering birds in a bid to produce medical compounds, a herculean task that scientists have struggled with for decades. The US FDA has approved only one chicken-derived drug in the past—an expensive treatment for a rare liver disorder. (Some users may encounter a paywall.)

One dad, one hundred babies

A look at the companies offering surrogacy to the ultrarich—including Chinese men taking their reproductive cues from Elon Musk.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Some female tardigrades reabsorb their eggs if no male fertilizes them

The eggs are laid in skin that has detached after molting. These species undergo sexual reproduction, but others reproduce asexually, with females producing clones from unfertilized eggs. Some hermaphrodite species have both male and female reproductive organs and can self-fertilize.

The history of molecular gastronomy, from thickening yolks with alcohol to making art with food

Before understanding why they worked, humans used scientific principles, including designing solutions and analyzing outcomes, to develop preservation methods like curing meat and fermenting vegetables. By the 20th century, the application of industrialized food preparation to smaller kitchens set the stage for the subdiscipline of food science.

Before Dawkins, other biologists proposed the power of mutating ideas

Nobel Prize winner Jacques Monod proposed, “Ideas have retained some of the properties of organisms. Like them, they tend to perpetuate their structure and to breed; they too can fuse, recombine, segregate their content; indeed they too can evolve, and in this evolution selection must surely play an important role.”

Abiogenesis explains how Earth's natural processes could have formed organic matter

The theory details how chemical interactions in hydrothermal vents and shallow ponds billions of years ago could have created lipids, proteins, and RNA. As these interactions involve water, life is thought to have started in oceans.

The human body in 3D

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A dispute about the origin of twitching frog legs led to the invention of the first battery

Experiments by Luigi Galvani on exposed frog leg nerves showed activity when they were hung from iron railings and brass hooks, suggesting the existence of "animal electricity" that discharged when connected to metals. Alessandro Volta's voltaic pile, which stacked metals with an inorganic electrolyte, showed that electricity originates from chemical reactions.

Wealthy Egyptians slept on woven beds to allow air circulation in hot climates

The history of beds is a fascinating look at economics, social science, and cultural beliefs around what takes place during sleep. This brief survey of the history of bed-making begins roughly 5,000 years ago and runs through ancient Egypt and Rome to modern Europe. Take a look here.

Stonehenge has produced wild origin stories

Built before the wheel was invented, Stonehenge inspired increasingly fantastical explanations—from a 12th-century tale of Merlin and Nephilim giants to 1960s claims that aliens built it alongside the pyramids.

Traditionally, a glut of unused eggs during Lent would be decorated at Easter

That's how the tradition started, at least in the more orthodox (or strict) branches of Christianity, which didn't eat meat, dairy, or eggs the whole period. By the end, there was more than could be eaten, so decorations ensued.

The universe may have been reborn from a state of emptiness

Some physicists propose the universe might be the latest in an eternal cycle of universes, each emerging from the empty remains of the one before. This model is inspired partly by Norse and Egyptian myth, suggesting the universe is a cosmic ouroboros—a self-consuming serpent representing an eternal return.

Scientists now know why wombats poop cubes

For years, scientists have been wondering why wombat poop is cube-shaped (yes, really). Now, they say they have got to the bottom of the mystery.

Why pregnant teachers were banned from classrooms

Until the 1970s, many schools required pregnant teachers to leave the classroom by mid-term. In 1974, the Supreme Court ruled these policies unconstitutional, establishing that women could choose to keep working while pregnant.

The history of the WNBA in 60 seconds

Women’s basketball began in 1892, less than a year after the sport’s invention, but restrictive clothing and societal norms posed early challenges. Senda Berenson modified rules to make the game more “suitable,” limiting dribbling and court movement. By 1971, women began playing with rules similar to men’s, and Title IX in 1972 provided federal funding, opening doors for future athletes.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

The first robot in literature may have been a 'mechanical man' in 1907's 'Ozma of Oz,' a book in L Frank Baum's 'Wizard of Oz' series.

Learn more about the history of fireworks, which dates back to an accidental invention during an alchemist's quest for information about immortality.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Double world record holder Hunter Ewen helped conquer his fear of balloons, called globophobia, by training to win Guinness World Record titles for balloon inflation.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

Artificial coral reefs have been 3D printed from nontoxic, biodegradable terracotta clay, which coral polyps have used as a foundation for rebuilding marine ecosystems.

See the evolution of Ebola vaccine and treatment development.

Georgia O'Keeffe's flower paintings are often assumed to be sexual, though the artist claimed she was simply interested in highlighting the beauty of flowers that most people neglect

The first image of a black hole was captured by creating an Earth-sized virtual observatory from a network of eight radio telescopes.

In 1963, a basement renovation in Turkey revealed a passageway to a hidden, multilevel underground city that once housed as many as 20,000 people

The idea for the Federal Reserve was conceived in secret in 1910—with bankers donning duck hunt gear for disguise while traveling to a remote country club on Georgia's Jekyll Island

While the first exchange-traded fund (a 'basket' of different assets that can be bought and sold on a stock exchange) in the US only launched in 1993, the global ETF market has grown to more than $10T in the short time since.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

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How Amazon operates a 'flywheel' business model, a self-reinforcing cycle that drives continuous growth