The origin of LASIK eye surgery, from a lab incident to federal funding and widespread use

During LASIK surgery, a laser removes microscopic amounts of tissue from the cornea

Before surgery, a patient’s vision needs are incorporated with measurements and mapping of their eye’s surface to identify corrections to refractive errors. This ensures light entering the eye correctly focuses onto the retina to produce a clear image.

Laser technology powers communication, medical and manufacturing tools

Lasers are used when scanning groceries, printing documents or undergoing cosmetic procedures to enhance efficiency, precision and accuracy. Missile defense, targeting and optical communication systems have made using laser technology habitual in the military.

Restoring vision in impaired patients via CRISPR

Since CRISPR was revealed as a gene editing tool in 2012, it has been on an accelerated track to real-world applications. Among other clinical demonstrations, doctors have now injected a CRISPR treatment directly into eye cells, helping vision-impaired patients see shapes and colors again.

New eye implant clinical trial recruiting in 2026

University of Southern California researchers have launched a phase 2b clinical trial of a stem cell implant designed to restore vision in people with advanced dry macular degeneration. Patients will be randomized to receive the stem cell implant or a simulated procedure and placebo implant. This type of larger, second-stage clinical trial is designed to confirm efficacy and dosing and to look for side effects. It's one of the stages that precedes the US Food & Drug Administration approval of a device.

Scientists have diverted the path of lightning using lasers

A proof of concept for a laser protection system, which could be used to protect launchpads and airports in the future, was conducted on the Säntis mountain in northeastern Switzerland. Rapid laser pulses heated air molecules, creating a more conductive, 50-meter (164-foot) path for the electrical discharge to travel through.

Random lasers can be created from biomaterials, such as peanuts and birch leaves

Rather than creating a narrow beam of light via amplification in an optical cavity, the random laser produces a red glow by scattering photons created in the natural pores of a peanut kernel after it has been injected with a solution of light-generating carbon dots derived from birch leaves.

Lasers could be the most cost-effective tool for clearing dangerous space debris

A NASA study found that lasers from ground- and space-based systems could utilize the momentum of light to safely push smaller debris out of their orbits. These systems would need to be accompanied by amendments to international space law, which prevents any nation from touching debris from another country, among other strategies.

How to cook food with lasers

Creative Machines Lab at Columbia Engineering have developed a system of software-controlled lasers to cook food with precision, retain moisture with the final-cooked product, brown food within its original packaging, and create an entirely new meal creation process for a consumer. Watch this three-minute video to see for yourself.

Scientists create contact lenses that give you infrared vision

Scientists have created lenses that use nanoparticles to convert infrared light into visible light, allowing human eyes to observe previously invisible parts of the electromagnetic spectrum. This technology may help colorblind individuals by converting colors they cannot see into wavelengths they can.

Why surgeons implant teeth into eyes

What if the thing that restored your vision… was your own tooth? That’s exactly what happened to Brent Chapman. After 20 years without sight, a bizarre surgery using his tooth as a lens restored his vision.

Credit for inventing the laser was fought over for nearly three decades

Although Theodore Maiman built the first working laser in 1960, Gordon Gould coined the term earlier. Charles Townes and Arthur Schawlow of Bell Labs filed a patent after Gould came up with the idea and name, but before Gould filed his patent.

A laser energy system has allowed scientists to achieve fusion ignition

In 2022, scientists used lasers to create a powerful implosion that bound hydrogen isotopes together, releasing more energy than was input into the system. Research is ongoing to achieve this self-sustaining reaction with larger yields and energy gains.

Laser procedures have made tattoo removal much more common

An increasing number of Americans, including high-profile celebrities, get tattoos removed because laser removal has become more advanced and cost-effective. The tattoo industry is adjusting to this mainstream trend.

Laser skin treatments can promote the production of collagen

Skin resurfacing vaporizes the top layer of skin to reveal healthier, new skin, while collagen can give the skin structure and elasticity. Such procedures treat scars and burns, but may leave light spots on the skin.

An overview of the National Science Foundation and the technologies it has helped fund

Established in 1950, the federal agency has provided billions of dollars to over 300,000 researchers, entrepreneurs, and students to conduct research across all seven continents. These funds have contributed to major technological achievements, from the invention of the internet to the first image of a black hole.

Gamma Knife surgery uses incredibly precise, high-energy light to treat patients

A form of brain stereotactic radiosurgery, this non-invasive technology concentrates beams of light onto specific tumors to damage the DNA of malignant cells, killing them. The gamma rays used are in the same part of the electromagnetic spectrum as those produced in nuclear reactions, cosmic ray collisions, and radioactive decay.

What's next for surgical robots?

Since robots were introduced into the operating room in 2001, their patients have seen improved recovery times and decreased risks of infection. This article describes what's next for surgical robots, which, so far, have remained under human...

See top-down views of Washington state's geology with cutting-edge lidar

Lidar is a revolutionary tool that creates visual models of landscapes using rapid light pulse measurements. Geologists in Washington state have deployed the technology to study the state's fault lines, landslides, tsunami inundation zones, and much more.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

An LSD scientist's role in a US mind control project

Within a decade of LSD's discovery, the US government had launched a secret initiative involving hypnosis and hallucinogens. LSD researcher Louis Jolyon West conducted experiments for the CIA's MKUltra project, which focused on the potential of mind control. He later took part in a criminal trial that hinged on testimony whose sourcing was seemingly inspired by MKUltra experiments. This article explores light shed by West's personal archive.

SpaceX was built to achieve Elon Musk's vision of making humans an interplanetary species

Learning quickly from early Falcon rocket failures and clashes with vendors and safety regulators, the company has focused on reusability as a first step to reaching Mars and is backed by NASA funding to do so.

Watch a firsthand account of Hubble's first service mission to repair its faulty mirror

Hubble senior project scientist David Leckrone recalls initial public ridicule over the microscopic manufacturing error that put NASA's reputation at stake. In this behind-the-scenes interview, he breaks down the innovative fix deployed by space shuttle astronauts during Hubble's first servicing mission.

The man who turned his leg into a hotspot

Biohacker Michael Laufer recently had a 512GB drive implanted in his leg, which can store data, stream music or movies, and power a hot spot and mesh network. It's called the PegLeg, and WIRED's Daniel Oberhaus spoke with Laufer about the device and the field of biohacking.

Leprosy affects the skin, eyes, and upper respiratory tract

Untreated, the disease can lead to permanent nerve damage and the loss of sensation in arms, legs, and other extremities. The exact form of transmission remains unclear, but scientists suspect it is spread via respiratory droplets over a prolonged period. (Warning: Graphic content, including photos of deformities.)

Dr. Bernard Fisher pioneered lumpectomy as a treatment for breast cancer

Dr. Bernard Fisher was a surgeon-scientist who developed and discovered cancer treatments that changed the way we treat and understand breast cancer. Despite these contributions, Fisher was also the subject of a congressional investigation that tarnished his reputation. Listen to the "Less Radical" six-episode podcast series covering the complex story of this influential doctor.

Cosmetic surgery during the Edwardian era

This 23-minute video explores cosmetic surgery in the United Kingdom during the Edwardian era, from about 1901 to 1914. Reconstructive surgery already existed by then, though it wasn't considered elective as it was used to repair damage suffered...

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

The history of many kitchen appliances involves unexpected discoveries and applications, including wartime radar turned hamster defroster and replacing an 'ice king' with heat-stealing boxes.

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

SpaceX's S-1 or 'prospectus' revealed many previously unknown details about the company, including its unprofitability despite doing $18.7B in revenue in 2025, exactly how many voting shares Elon Musk will have in the company (roughly 85%), and more.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Roughly 43 million US borrowers owe roughly $1.7T in student debt, the second-largest source of consumer debt behind mortgages.

Long before Major League Baseball began allowing instant replay for balls and strikes, an umpire reluctantly used the technology to determine whether a hit was a home run, a move that inadvertently ushered in a new era for the sport.

Visualize the path of every solar eclipse from 1900 to 2099 and see what each looks like when observed from different locations on Earth.

Hedge funds, the private investment firms that trade a wide swath of financial assets, make money by imposing steep fees on investors and from the fund's investment performance.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

Legendary architect Frank Lloyd Wright designed the SC Johnson headquarters in Wisconsin, aiming to make a cathedral-like workplace

When a Paris department store hesitated to sell Estée Lauder's perfume, she 'accidentally' broke a bottle, causing the smell to spread throughout the store and shoppers to start asking to buy the scent.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Sony set the standard for cylinder-shaped batteries when it repurposed manufacturing equipment used to make rolls of magnetic recording tape.

The animatronic shark from Steven Spielberg's 'Jaws,' the first modern blockbuster, was a complex underwater apparatus called 'Bruce.'

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.