The WHO labeled aspartame as 'possibly carcinogenic' but US regulators consider it safe

This 2022 study is one of the findings that prompted WHO to label aspartame as 'possibly carcinogenic'

This French study analyzed online periodic self-reported food journals from more than 100,000 people for a median of almost eight years and linked aspartame consumption to a roughly 15% increased cancer risk. It found that the people who consumed higher levels of aspartame had elevated cancer numbers—particularly breast and obesity-related cancers.

Artificial sweeteners are considered safe for most people

These sugar substitutes are generally preferred because they are sweeter than sugar and can be used in smaller amounts while still getting a sugary taste. Though generally regarded as safe, sugar substitutes can cause flare-ups for individuals with bowel disease, and researchers are investigating how these substances affect gut microbiome health. Aspartame can also cause health issues for individuals with a rare genetic disease called phenylketonuria.

See how much daily sugar substitute intake the FDA considers to be safe

The agency states in this PDF graphic that a person weighing about 132 pounds would have to consume roughly a couple dozen sweetener packets daily—or more—to reach unsafe levels of consumption. The accumulated consumption would be across all sources, including diet beverages, sugar-free candies, and actual packets added to coffee.

Saccharin was banned in Canada in the 1970s, but regulators may allow its use once again

The product, commonly known as Sweet'N Low, was banned in Canada in the late 1970s due to research indicating that the sweetener could cause cancer in lab rats. Subsequent studies have found that the rodent findings didn't hold true for humans, and so Canadian regulators state that they are considering updating their stance to allow the product to be added to certain foods (the product is currently allowed in the US).

Aspartame was a surprise discovery from a lab working on gastric ulcers

As with saccharin and cyclamate, the aspartame discovery arose from its discoverer tasting something sweet from his workplace. In 1965, American chemist James Schlatter licked a white powder off his finger as he picked up a piece of paper and was startled to discover it tasted sweet. He applied for a patent for the substance, and received it in 1970. It is now one of the most popular artificial sweeteners. (Some users may experience a paywall.)

Unlike its Mexican counterpart, American Coca-Cola contains high-fructose corn syrup rather than sugar

There are a few reasons why American Coke turned away from sugar in the 1980s, but none of them are related to consumer health. This Reader's Digest article breaks down the history behind Coke's recipe change, explaining why the company continues using high-fructose cough syrup.

Acrylamide forms naturally during high-heat cooking through the Maillard reaction

While studies have shown it can damage DNA and potentially cause cancer in mice, humans absorb and metabolize acrylamide at different rates, introducing uncertainty in the research's applicability to humans. Some international health agencies have nonetheless recommended avoiding darker roasts when cooking starchy foods.

Coca-Cola made up roughly 19.2% of US carbonated soft drink market share as of 2023

Separately, Diet Coke made up about 7.8% of US market share that year. Pepsi was responsible for 8.3% of market share, as was Dr. Pepper.

Alcohol is responsible for 5% of cancer cases and 4% of cancer deaths in the US

Alcohol consumption is linked to at least eight different types of cancer, including liver, breast, and throat. The risk comes from ethanol, which turns into DNA-damaging acetaldehyde. Experts recommend limiting intake or quitting altogether to reduce long-term health risks.

Chocolate can be deadly in humans, but only after consuming extraordinary quantities

Based on tests with mice, the lethal dose of chocolate is estimated to be no more than 1,000 mg/kg. This means that the lethal dose of dark chocolate for the average US adult is about 6.5 kilograms (14.33 pounds), or about 8,300 Hershey's kisses, in one sitting.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

The FDA claims microplastics have not yet been shown to pose a health risk

Although microplastics and nanoplastics are found in many foods and environments, their presence does not violate regulations. Additionally, as of 2025, the administration believes evidence does not confirm that detected levels harm humans.

Investigation finds 'influencer' dietitians paid to promote sugar, supplements on social media

A joint investigation by The Examiner and The Washington Post found that food, beverage, and supplement corporations and groups have paid registered dietitians on social media to promote content that goes against decades of scientific evidence on...

Mycotoxins are toxic compounds produced by fungi—some show up in food

About a quarter of the world’s agricultural products are contaminated with mycotoxins. Some of these compounds can cause serious health problems, including cancer, so the US government has set up monitoring programs to detect them in our food and in animal feed. Humans can become ill if they eat contaminated food, but also if they ingest products from animals that had previously consumed these toxic compounds, such as milk from a cow that ate contaminated corn.

The dietary market is worth more than $60B

Listen to this question and answer session with the US Food and Drug Administration about dietary supplements—vitamins, minerals, probiotics and similar products people may buy in liquid, pill, or powder form. They are categorized legally as a category of food and can be legally brought to market without the FDA even knowing about it, though consumers can tell FDA about issues with the products and FDA can take action to remove dangerous or unlawful items after they're available.

Tattoo inks are largely unregulated by the FDA

With hundreds of ink manufacturers, all unregulated by the FDA, it’s hard to determine the exact ingredients in tattoo inks. Some pigments may contain carcinogenic chemicals, such as heavy metals and aromatic hydrocarbons, or even bacterial contaminants. Red ink often causes allergic reactions and may even contain lead or mercury.

America's top causes of death are heart disease, cancer, accidents, and stroke

Heart disease killed more than 680,000 people in 2023 and cancer killed around 613,000 people that year. Both causes of death are far above the next leading cause of death—accidents, which numbered around 223,000. Provisional data for 2024 indicates the leading causes of death remained the same.

How a government chemist founded the FDA—by poisoning people

The Poison Squad tells the story of government chemist Dr. Harvey Wiley who, determined to banish these dangerous substances from dinner tables, took on the powerful food manufacturers and their allies.

FDA has removed black box warnings from HRT for menopause

The agency removed the label in 2025, reversing its 2003 decision to warn women about HRT's links to stroke risk, developing cancer, and heart disease. Years of accumulating research have found that the risks had been overstated and unnecessarily deterred hormone therapy use. The agency still warns against using certain estrogen-alone products, however, due to elevated endometrial cancer risk.

US federal law dictates that all ads must not be deceptive

It also dictates that all ads must be “not misleading, and, when appropriate, backed by scientific evidence.” However, enforcing these laws can be difficult given the massive number of ads that run all over America each day. This explainer on the subject from the FTC provides more information.

Coffee is, generally, good for your health

While overconsumption certainly has its drawbacks—hello, not sleeping until the sun rises—on the whole, coffee is fine, even beneficial, for your health. It can even help prevent serious health conditions, like heart attacks and liver cancer.

The World Anti-Doping Agency has banned many peptides

The global body has an entire section dedicated to banned peptide hormones, including ones that may stimulate growth hormones and testosterone. BPC-157 was added to the list in 2022.

The Office of Chemical Safety and Pollution Prevention regulates toxic substances

This office evaluates and manages risks from industrial chemicals and pesticides. It reviews new chemicals before they enter the market, restricts hazardous substances, and promotes safer alternatives to protect human health and the environment.

It seems like we shouldn’t have to say this: Cheese is not like crack

While news reports may claim cheese is addictive, the facts behind the research show cheese and crack have little in common. It appears that highly processed foods with high levels of sugars and fat, rather than cheese specifically, are most closely associated with addictive-like behaviors. In fact, cheese ranked lower than foods like pizza, chocolate, and fries in terms of its addictiveness.

As of 2026, the majority of US states have unsafe radon exposure levels

Alaska, South Dakota, Pennsylvania, Ohio, and Washington top the list of states with exposure levels above 4 picocuries per liter for this naturally occurring radioactive gas. While these state-level averages vary from one county, municipality, and home to another, the EPA encourages those in the highest-risk states to test their homes.

Over the years, the USDA has changed its definitions of healthy eating

The US Department of Agriculture began offering eating advice in 1894 and has updated its guidance as both science and politics have evolved. In the early 20th century, its guidance emphasized recommended minimum servings of important foods; in later decades, its visual guides became more nuanced, illustrating the composition of a healthy diet and encouraging exercise.

11 people died from firework injuries in the US in 2024.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Dozens of S&P 500 stocks, including Coca-Cola and Walmart—known as the dividend aristocrats—have increased dividends every year for 25 years

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

In 1984, Operation Smash Hit intentionally crashed a 239-ton train into a nuclear waste canister at 100 miles per hour to prove the canister's safety, which remained completely intact and lost just 0.29 of its 100 pounds of pressure.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

The most expensive ad of all time was for Chanel No. 5 perfume and cost roughly $33M to produce in 2004—about $57M in today's dollars.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

The story of Dollree Mapp, whose legal challenge over her 1957 conviction for possessing "obscene material" led to a major strengthening of the Fourth Amendment

Up to a million Girl Scouts sell about 200 million cookie boxes every spring, generating $800 million, largely because refusing a child is frowned upon

The American Society of Civil Engineers' infrastructure report card gave the US a C in 2025, its highest grade since the project launched in 1998.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Power lines are dotted with large, brightly colored balls to improve the visibility of these thin wires to helicopters and small planes and help prevent potential crashes.

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.

This site reaches millions of visitors who are tired of AI chatbots and seeking human connection. Pretend to be an AI chatbot and ask questions, provide answers, and draw for people in real time.

Prince's sexually explicit 1984 track 'Darling Nikki' attracted the ire of the Parents Music Resource Center, an advocacy group that inspired the Parental Advisory sticker, even though the song ends with a Christian message.

Browse a detailed visual analysis of over 200,000 similes—comparisons that often use 'like' or 'as'—from popular fiction to see how frequently writers the same idiomatic expressions.

The price of gas is a composite made up of several different factors, with the federal gas tax making up less than 20% of what drivers pay at the pump.