About 95% of people are naturally immune to leprosy

People can—and have—contracted leprosy from armadillos

A 2011 study linked multiple human cases to the handling of armadillos or the consumption of their meat. The research couldn't document direct transmission, but did find that the animals and humans shared the same exact strain of the disease.

Leprosy affects the skin, eyes, and upper respiratory tract

Untreated, the disease can lead to permanent nerve damage and the loss of sensation in arms, legs, and other extremities. The exact form of transmission remains unclear, but scientists suspect it is spread via respiratory droplets over a prolonged period. (Warning: Graphic content, including photos of deformities.)

Leprosy symptoms may appear 20 years after infection, so contact tracing isn't possible

The standard approach for tracking disease transmission isn't realistic for this disease because symptoms may take decades to manifest. As a result, disease transmission is still not fully understood.

Up to 225 cases of leprosy in the US are diagnosed each year

Most cases in the US are imported, meaning someone was infected in a country where it was more common. Since symptoms can sometimes take decades to appear, tracing the origin of the disease can be hard.

Nerve axons become damaged by leprosy, so patients may lose feeling in their skin

Infection of the peripheral nerves—nerves outside the brain and spinal cord—is a known complication of leprosy. That damage can cause patients to lose their sense of touch and the ability to feel pain or temperature in affected areas, leading to accidental injury.

More than 200,000 people are diagnosed with leprosy annually

The disease still occurs in more than 120 countries. Brazil, India, and Indonesia continue to report more than 10,000 new cases annually.

81% of Florida's leprosy cases occur in central Florida, raising concerns

Researchers noted in 2023 that about one-fifth of new US leprosy cases were reported in the central part of the Sunshine State. What's more, about a third of the new US cases overall appear to have been acquired locally, raising questions about whether the disease is now naturally occurring in parts of the southeastern US.

Recent research indicates leprosy was present in the Americas before European settlers

New research published in 2025 upended long-held notions that the disease was introduced to the Americas by European colonizers. Evidence of a lesser-known leprosy-causing bacterium was found in ancient human remains that date back 4,000 years.

Leprosy bacteria are sometimes grown on mouse feet for research

The main leprosy-causing bacterium can't be grown in a petri dish, so the disease is challenging to study in the lab. For research purposes, it has been grown in the foot pads of mice.

See examples of leprosy in the Bible—a broad term for skin ailments in ancient times

People afflicted with leprosy in the Bible may have had a range of different skin diseases, rather than what's clinically diagnosed as Hansen's disease (leprosy) today. In the Bible, as in many traditional societies, those with the disease were often considered unclean or sinful.

Read excerpted accounts from some of the 8,000 residents with leprosy on Moloka'i

Accounts preserved by the Kalaupapa National Historical Park describe how residents felt about being sent to live in this remote location and knowing they would never be allowed to leave. In 2012, 20 residents with the disease continued to voluntarily live in the area.

More than 1 in 7 people worldwide have had Lyme disease

Research published in 2022 suggests that 14.5% of the world's population has contracted Lyme disease. Researchers arrived at that estimate by analyzing the presence of Lyme disease antibodies (indicating prior infection) across 89 studies conducted between January 1984 and December 2021. The works collectively included blood samples from more than 150,000 people. (Some user may encounter a paywall.)

Wild chimpanzees have been spotted with leprosy lesions

In research published in 2021, scientists reported discovering cases of leprosy in wild chimpanzees from Guinea-Bissau and the Ivory Coast—marking the first time the disease has been found in any nonhuman species in Africa. They confirmed that leprosy was the cause of the deformities by testing the animals' poop for the presence of the disease-causing bacteria.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

Hand, foot, and mouth disease spreads easily—including via fomites

The common ailment spreads through respiratory droplets, touching infected secretions like poop, but also by touching virus-laden fomites, which are contaminated objects such as doorknobs or toys.

Watch an expert's take on the rare disease hantavirus—and why it's not of great concern to the general population

This rare zoonotic disease, transmitted to humans primarily through infected rodent droppings, urine, or saliva, is rarely spread between people. The disease was of particular concern in spring 2026, when an outbreak occurred on a 150-person cruise ship, prompting a flurry of action, including contact tracing for passengers in their home countries. The disease can be fatal. But early care—primarily oxygen support—can help patients survive.

Chagas disease can be transmitted to a fetus during pregnancy

Researchers estimate that 63 to 315 cases of congenital Chagas disease occur annually in the US. Roughly 20 to 30 percent of all Chagas disease cases will progress to cardiac or gastrointestinal disease.

Improved 19th-century sanitation meant kids encountered polio later, with worse results

Almost all children likely used to contract poliovirus, but scientists suggest that when infants encountered it very early in life—due to poorer conditions and hygiene—they still had some maternal protection from pregnancy or through breastmilk, so the symptoms were more flu-like.

Most people breathe fungal spores daily without getting sick

Most people breathe in hundreds of Aspergillus fumigatus spores daily without getting sick—it’s a common microscopic fungus in our environment. But people who are severely ill, including those who have undergone an organ transplant, are at risk of developing infections from these spores.

Rabies is nearly 100% fatal once symptoms appear

Rabies, a viral disease attacking the central nervous system, is nearly always fatal once symptoms appear. It spreads through the infected animal saliva (typically through bites) and causes encephalitis, leading to severe neurological symptoms and death. See how the lyssavirus—the bugs behind rabies—work once inside the body.

About two-thirds of humans lose their ability to produce lactase after weaning

Lactase is an enzyme that digests lactose—a sugar in milk and dairy products. While genetics strongly determines lactase persistence, factors like famine, disease exposure, and gut bacteria also influence symptoms and evolution.

Amish kids have far fewer allergies than the general population

Only about 7% of Amish children in a northern Indiana community have tested positive for common allergens in routine skin prick tests, whereas half of the general US population tests positive for them. Asthma is also extremely uncommon among the Amish, even when compared with other farming communities. Researchers are interested in exploring if approaches like exposing kids across the general population to Amish farm dust might stave off some allergies.

Cholera can persist in the environment, unlike smallpox, which needs a human host

Vibrio cholerae is the pathogen that causes cholera. It can reproduce in the environment without a human host, which means it's formally called a facultative pathogen. Obligate pathogens need a host to reproduce. Examples of obligate-based diseases include leprosy and smallpox.

Poison ivy's rash-causing compound is found in the plant's roots, stem, and leaves—so coming into contact with any part of the plant can lead to rashes for the 85% of people who are allergic to it.

80% of schizophrenia cases may be inherited

Some research suggests that anywhere between 60% and 80% of people with schizophrenia had genes that predisposed them to the syndrome. That high rate has fueled interest in further exploration of what environmental and lifestyle factors cause some people with that genetic risk to develop the disease when others with the same genetic risks do not.

Being near a lightning strike—even without getting struck—can be fatal

Because animal tissue is generally more conductive than soil, electricity moving along Earth's surface after a strike tends to travel up and back down an animal's legs, discharging dangerous amounts of energy along the way, with risks increasing the farther apart the legs are. This ground current accounts for about half of all lightning-related deaths and injuries in humans.

Poison ivy can cause rashes any time of the year

This myth-busting article about poison ivy notes that all parts of the plant contain urushiol, the oil that triggers our allergic response, so if you are in the woods in winter you may be still encounter the plant—and urushiol.

Scientists have struggled to pin down Ebola's natural reservoir species for decades, but the available evidence suggests that it's very likely fruit and insect-eating bats found in Africa.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

About 12.5% of US adults experience a phobia in their lifetime, a diagnosis that hinges on the intense fear interfering with daily life and persisting for at least six months.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Tattoos remain visible on your skin thanks to immune cells called macrophages

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

Despite being favored by 87% of Americans, Congress does not have term limits.

While El Niño moves warm Pacific Ocean waters east along the equator, La Niña moves them west, shifting where rainfall will become more common for months.

Pure water does not conduct electricity because this flow of energy requires the movement of charged particles, and water is a neutral molecule.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Coral polyps reproduce via broadcast spawning, where entire reefs simultaneously release reproductive cells for about one hour, once a year.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

When a Paris department store hesitated to sell Estée Lauder's perfume, she 'accidentally' broke a bottle, causing the smell to spread throughout the store and shoppers to start asking to buy the scent.

Abraham Lincoln was almost assassinated weeks before his inauguration as he traveled from Illinois to DC through Baltimore in 1861; it took two independent claims for Lincoln to be convinced the threat was real

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.