Patient H.M. revealed that the hippocampus was responsible for memory formation

The hippocampus, a structure in the brain, plays a crucial role in memory formation

The seahorse-shaped structure transfers short-term memories to long-term storage during sleep. It is located in the temporal lobes, above each ear, and aids in spatial navigation and remembering directions.

The hippocampus plays a central role in dreaming

It's theorized that the hippocampus—a brain structure involved with memory formation and the simulation of imagined and novel scenarios using those memories—plays a major role in dreaming. Studies of people with damaged hippocampi show that they still dream, but their dreams lack the richness of detail described by others.

Researchers use the brain's ability to edit memories to explore memory deletion

Scientists have successfully implanted false memories in mice after studying how the editing process works in the brain. Beyond potentially deleting memories in those with PTSD, upcoming research may allow clinicians to forecast the onset of neurodegenerative diseases.

Memory exists as multiple types stored across various brain systems

Memory isn't one uniform function—it's made up of multiple systems, like declarative (facts/events) and non-declarative (skills/habits), which involve different brain areas such as the hippocampus, amygdala, and cerebellum.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

Research suggests the brain maintains connections to lost limbs

Decades-old research suggested brain reorganization after amputations, but brain scans show unchanged limb representations. Phantom limb pain may result from such unchanged brain maps, which may enhance prosthetic limb control in brain-computer interface technology.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

Long-term memory formation may not need short-term memory

New research shows that long-term memories can still develop even when short-term memory formation is blocked, suggesting the brain uses separate pathways for short- and long-term memory. This discovery could help scientists open new avenues for treating memory loss in diseases like Alzheimer’s.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

Memory disorders disrupt the brain's ability to make, store, or recall memories

These disorders stem from reversible issues like vitamin deficiencies or irreversible causes such as stroke or dementia. Only one type of dementia—familial Alzheimer’s disease—is directly inherited and accounts for about 20% of Alzheimer’s cases.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

These areas of the brain are hard-hit in depression—but the changes are reversible

Depressed brains can have certain characteristic changes, including an overactive amygdala, reduced hippocampus size, and changes to the thalamus and neuromodulating chemicals in the brain.

A brain scientist's experience with a stroke

What happens when a leading brain scientist has a stroke of her own? Dr. Jill Bolte Taylor recounts moment by moment watching her brain function slow and then cease, followed by a prolonged recovery. Through this experience, she details what she learned about the phenomenon of stroke and how it has impacted her research ever since.

Schizophrenia is being studied with pea-sized 'mini-brains'

Brain organoid research is enabling researchers to study distinct electrical firing patterns associated with schizophrenia. These "mini-brains" that are constructed in the lab from patients' cells could lead to better diagnosis approaches and drug development.

The first identification of Alzheimer's was made in 1906

The first case of Alzheimer's disease dates to the early 20th century when Dr. Alois Alzheimer had 51-year-old Auguste Deter as a patient. Deter struggled with sudden memory issues and aggressive, irrational behavior. After Deter's death, Alzheimer examined her brain and found strange collections of molecular pileups.

How to remember names

Journalist Lisa Kanarek sought to become a “super-recognizer,” someone with exceptional face recognition abilities who never forgot a name. She enlisted the help of a neurosurgeon and a world record holder in memory. The experts suggested a few tips and tricks to connect names and faces and erase the need to say, "Hey, you!" again.

Everything you know about Phineas Gage is wrong

A stray spark sent a 3.5-foot-long, 1.25-inch thick iron rod through the brain of foreman Phineas Gage in 1848, creating a scientific case that has attracted onlookers for nearly two centuries. His life reportedly soon spiraled out of control, with his behavior tending toward selfishness and chaos. Evidence of these changes is far less common, with Gage's story bloated by fabrication, scientific prejudice, and artistic license.

In 1968, a Harvard Medical School committee issued the first neurological definition of death

The definition set a legal and medical precedent for how we define death, important for issues including organ donation. This 2020 video podcast discusses the history of brain death controversies and the variability in how death has been determined, including discussions in the late 1960s about when patients are considered dead in the context of organ donations.

Why 'spacing out' or dissociating may help reduce trauma awareness

Dissociation may have developed as a defense mechanism in the brain to help navigate intense emotional or physical situations by providing out-of-body experiences that put distance between the mind and the environment. However, in about 1.1% and 1.5% percent of the general population, a severe form of this separation can produce alternate identities, or alters.

Can your identity be preserved amid dementia?

Memory loss associated with progressive dementia raises questions about whether a person's identity can be maintained during the disease's progression. One outlook suggests we define ourselves by our social relationships—offering a potentially more humane approach to caring for those with dementia.

Whose bodies are held inside the American Museum of Natural History?

The American Museum of Natural History holds the remains of at least 12,000 people collected via purchase, donation, or expedition. This article by a professor of art crime details their attempt to identify the individuals whose remains the museum held. Amid questioning, AMNH announced it would change its human remains policy. At the time of the article's publication in October 2023, AMNH had few human remains on public display.

After the patient died, a latent pig virus was discovered inside his xenotransplant

Researchers studying the death of David Bennett Sr., the first gene-edited pig heart transplant patient, discovered potential factors that may have contributed to his demise. One finding is that there was a latent virus, called porcine cytomegalovirus (PCMV), in the pig heart, which may have contributed to dysfunction of the transplant.

A psychedelic hamburger led one member of the Manson Family, the murderous cult led by Charles Manson, to testify against the group's leader.

The evolution of the human brain

The human brain, in all its staggering complexity, is the product of millions of years of evolution. Read on to find out about brain size and intelligence, language and brain development, and more.

This is the human brain on the world's strongest psychedelic

Within seconds of inhaling a high dose of vaporized synthetic 5-MeO-DMT—a lab-produced substance that otherwise is naturally derived from the glands of the Colorado River toad—it induced slow brain waves. Such waves are typically associated with unconsciousness due to a coma or anesthesia, perhaps explaining why users describe feeling like everything falls away. The compound is currently in clinical trials for treating depression.

The scientists trying to prove Jackson Pollock's symbolism

Jackson Pollock is one of the most famous American artists in history. He is well-known for his Abstract Expressionist "drip paintings," which seemed to defy interpretation. But following the artist's posthumous bipolar diagnosis, a team of scientists attempted to prove that his symptoms, including mania and psychosis, caused Pollock to embed images under his thrown paint.

How helium enables MRI machines to look inside organisms

By cooling the machine's magnets with liquid helium to extremely low temperatures, they can generate and maintain powerful magnetic fields that align the hydrogen atoms in living things to point toward a patient's head or feet. A radio pulse nudges these atoms, which realign and induce a measurable signal in nearby electrical coils. These signals are captured in slices and then stacked into a 3D reconstruction.

This Indiana medical school encouraged students to get to know their cadavers' families

The school's anatomy professor instructed medical students to think of the cadavers they worked with as their "first patients"—using their names to acknowledge that this was a person and to exchange letters with the cadaver's family members if they agreed to participate. At the conclusion of the course, families were invited to a lab-based memorial service.

Clever Hans was a 1900s horse that was believed to be able to solve math equations, tell time, and read and comprehend German, until a psychology student discovered how he got his answers.

Researchers believe the brain consolidates memories, processes emotions, and plans for the future during dream states

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

Salvador Dalí believed he was his own dead brother, who had died nine months before he was born

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

The Mona Lisa's celebrity status and repeated restorations have obscured what made the painting so revolutionary for its time

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

Many legends about George Washington, including his supposed wooden teeth and the story of cutting down the cherry tree, lack evidence.

Fear or disgust related to clusters of holes and cracks, called trypophobia, may stem from evolutionary processes to help us avoid pathogens.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

The animatronic shark from Steven Spielberg's 'Jaws,' the first modern blockbuster, was a complex underwater apparatus called 'Bruce.'

Objects can be 3D printed with light by projecting 2D computerized tomography (CT) scans onto rotating cylinders of resin, which solidify upon exposure.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Jimmy Carter signed a 1978 bill that legalized home brewing, a move credited with kick-starting the craft beer industry.

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

See a 3D reconstruction of Tenochtitlan, the Aztec capital that was home to an estimated population of 200,000 to 400,000.

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.