See a timeline of the Human Genome Project

Nineteen years after its conclusion, scientists finish what the HGP started

The Human Genome Project mapped 92% of the human genome sequence upon its completion in 2003, leaving unreachable DNA regions unmapped. PacBio HiFi DNA sequencing allowed its completion 19 years later, with the additional mapping of 200 million DNA letters.

An overview of the Human Genome Project

The Human Genome Project was a groundbreaking global scientific effort to sequence the genome of humans and several organisms used in scientific research. The sequenced genome was created by combining the DNA of 20 people from Buffalo, New York.

The Human Genome Project was forced to accelerate due to a private competitor

Despite a 15-year target when it began in 1990, the Human Genome Project faced competition from Celera Genomics when it entered the sequencing race in 1998. Celera's aim to complete the human genome in three years pressured the HGP to complete their sequencing several years ahead of schedule.

The Human Genome Project met its goals, but its outcomes were overpromised

The Human Genome Project aimed to sequence the entire human genome, and initial hype suggested it would revolutionize disease treatment. In reality, the project's outcomes were more nuanced, failing to deliver immediate cures despite advancing the understanding of genetics.

See a timeline of landmark discoveries in the field of genetics

From the first genetic map of fruit fly genes in 1911 through the completion of the Human Genome Project in 2003, scientists have built upon each other's discoveries to further our knowledge of the human body and the genetic instructions that inform our traits and disease risks.

Explore the original goals of the Human Genome Project

The project goals emphasized DNA sequencing technologies and methods, which would lead to future treatments of genetic disorders. Exploring the project data's ethical and social implications was also considered.

Fully sequenced human genome will help scientists better understand disease

April marks the 20-year anniversary of the completion of the Human Genome Project, a monumental achievement that provided the first map of the human genetic code and advanced our understanding of human biology, disease, and potential treatments....

Think we decoded the genome in 2000? Nope. It was 2022.

Two decades after the draft sequence of the human genome was unveiled to great fanfare, a team of 99 scientists has finally deciphered the entire thing. They have filled in vast gaps and corrected a long list of errors in previous versions, giving us a new view of our DNA.

The $3B project scientists called 'junk'

In 1990, scientists set out to map all of human DNA. A $3B bet many called "junk." But the Human Genome Project's radical transparency and a race with a private company sped it to completion in just 13 years. Today, that once-contested map underpins nearly every breakthrough in genetics and personalized medicine.

See the history of DNA sequencing

DNA sequencing evolved from manual methods to automated, high-throughput technologies. The Human Genome Project was possible in the first generation of gene sequencing technology with the "chain termination method," which won developer Fredrick Sanger a Nobel Prize.

The Human Genome Project spawned numerous spinoff genetics projects

The Human Genome Project led to the development of techniques later applied to projects in microbial and plant biology, epigenomics, environmental and cancer genomes, and more. In the spirit of the HGP, data from these projects has been made freely available to develop new technologies.

In 2025, researchers in the UK began working on developing artificial DNA

The Synthetic Human Genome Project aims to one day construct human DNA, molecule by molecule, in the hopes of creating disease-resistant cells and synthetic chromosomes for study. However, critics warn it may be misused to create enhanced or modified humans.

About 70% of the Human Genome Project's reference genome came from one donor

Volunteers who donated blood to the Human Genome Project consented to using no more than 10% of their DNA, raising questions about the project's legality. Listen to how pressure from a private competitor may have driven officials to ignore ethical standards.

A student researcher working on the Human Genome Project shares their perspective

In a conversation with Ewan Birney, Director of the European Bio-informatics Institute, he discusses what it was like to be a PhD student working on the Human Genome Project in the months before the draft announcement and its impact on him and the field of genetics.

The messy story of humanity's genealogical past

For decades, scientists viewed the human fossil record and concluded Neanderthals, an early hominin, came before homo sapiens, or modern humans. The story became more complicated as technology advanced and ancient DNA samples were analyzed. This video breaks down the evidence, concluding the development of humanity was a lot messier than previously believed.

Charting 4,000 years of human history

Care to hang all of human history on your wall? This data visualization charts 4,000 years of humanity. This "histomap" was originally published in 1931 and sold for $1 per copy of the 5-foot-long chart. It was said to detail the course of...

Watch how DNA is packaged to a 10,000th of its original size in a cell

In humans, the 2-meter (6.56-foot) molecule wraps around spool-like proteins called histones, forming beads—nucleosomes—that fold up into fibers. These fibers—chromatin—form loops through folding that compress into larger fibers, which tightly coil together to form a chromosome.

The first criminal conviction through the use of DNA evidence was in 1988

Chromosomes contain markers where short DNA sequences repeat a variable number of times from person to person. A DNA profile is constructed by identifying the number of repeats across 20 regions throughout a genome, which can be compared against a database. DNA paternity tests work similarly by comparing markers between children and their fathers. (Some readers may experience a paywall.)

Up to 8% of the human genome consists of ancient viral DNA

Human endogenous retroviruses are remnants of infections that affected human primate ancestors millions of years ago and were passed on by infiltrating sperm and egg cells. Studies have shown that this DNA may play a role in immune responses and in placental formation.

Visualizing the genetics of SARS-CoV-2

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, began with an outbreak in Wuhan, China in December 2019, and rapidly spread worldwide in early 2020. On March 11, 2020, the World Health Organization declared COVID-19 a global pandemic, leading to widespread lockdowns, travel restrictions, and economic disruptions.

A timeline of Google's growth

As of 2025, Google will approach its third decade of existence. A period that's seen the company go from dominating the search market to the launch of one billion-user product after another, from Gmail to YouTube. This detailed timeline lays out what happened when, laying out Google's history in detail. It marks key milestones, like the introduction of Google Maps, and what year they happened.

Explore a timeline of the International Space Station National Lab

In 1984, President Ronald Reagan called for establishing a human presence in space, which began with NASA astronaut Bill Shepherd and Russian cosmonauts Yuri Gidzenko and Sergei Krikalev on November 2, 2000. Humans have continuously occupied the ISS every day since.

Key milestones in the history of the World Health Organization

The World Health Organization, a UN agency founded in 1948, was first proposed at the 1945 UN Conference to coordinate global health efforts. This interactive timeline marks the WHO’s 75th anniversary with major public health milestones.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Visualize the growth of the Linux kernel source code, which surpassed 40 million lines in 2025

Version 0.01 of the program authored by Linus Torvalds in 1991 spanned approximately 10,000 lines of code and has progressively grown to accommodate the management of an increasing number of hardware and software components. The kernel grows by an estimated 400,000 lines of code every two months.

The origin of the World Wide Web, plus a look at its first website and web browser

Invented by Tim Berners-Lee in 1989 while working at CERN—home of the world's largest particle physics laboratory—the Web was developed to facilitate the sharing of information among scientists at institutions worldwide. By the end of 1990, the first Web server was operational as a proof-of-concept on a NeXT workstation.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.

US housing costs have risen by roughly 175% between 1991 and 2026—but a growing number of Gen Zers are becoming homeowners anyway. In 2025, 4% of homebuyers were Gen Z, up from 3% the year before.

Track the location of the Voyager probes, currently between 13 and 15 billion miles away from Earth.

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

The US first hosted the World Cup in 1994, a tournament that lives in soccer infamy for its poor planning and the murder of Colombian player Andres Escobar, who'd accidentally scored on his own net.

When you complete a CAPTCHA on a website to prove you are human, you may be unknowingly training algorithms for self-driving cars, whose systems require training data to help identify crosswalks, bicycles, and other outdoor objects.

Trace how the Bill of Rights, inspired by centuries of political theory, took shape between 1774 and 1789.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Before humans, the Soviet Union and the United States sent animals—including apes, dogs, and cats—to space during the Space Race.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

Domino's Pizza's 30-minute delivery guarantee was responsible for the chain's 1980s surge, but it was discontinued after the company was found liable for delivery driver accidents.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.

In 1945, Surrealist artist Salvador Dalí and legendary animator Walt Disney began collaborating on a short film that was not completed until 2003, years after both men had died.

'Shogun,' a 1980s TV series, helped popularize sushi in the US by stimulating an American interest in Japanese culture.

Take a 3D tour of the Hajj, Islam's annual pilgrimage to Mecca, undertaken by over 1.5 million Muslims.