One of the leading theories behind muscle movement

Complex molecular reactions in our tissues cause muscle contraction

When we want to move a muscle, a signal travels from the brain and into the muscle cells in question, sparking a chemical reaction that causes the muscle's smallest contractile units—sarcomeres—to shorten, forcing the muscle to contract.

Muscles fatigue due to the loss of energy like ATP and glycogen

Adenosine triphosphate fuels muscle contraction, and with each contraction (like during exercise), the amount of ATP reduces. ATP helps potassium and sodium move across muscle membranes, generating ions and helping to contract the muscle.

Myokines are molecules that facilitate some of the benefits of exercise

When muscles contract, they release ‘hope molecules’ (myokines) such as IL-6 and irisin. These proteins then travel through the bloodstream to reduce inflammation, improve insulin sensitivity, and even support brain repair. This piece illustrates how movement triggers a systemic healing cascade throughout the human body.

How skeletal and smooth muscles differ

Skeletal and smooth muscles are two of the three muscle types found throughout the body. The former is attached to bones via tendons, enables limb movement, and is consciously controlled. The latter is found lining blood vessels and hollow organs (e.g., the intestines, stomach, and esophagus) and is managed by the autonomic nervous system, which means it's outside conscious control.

How does food move through the body?

Food passes through the digestive system via muscle movement known as peristalsis, during which a rippling contraction slowly pushes content through tubular organs, such as the esophagus and intestines. This is similar to what happens when one squeezes a tube of toothpaste, contracting the tube behind the content and forcing the tube in front of the content to expand, allowing the content to move forward.

How does muscle memory work?

Muscle memory is less about remembering how to ride a bike and more about what's happening in muscle cells. Increasing the cells' size, say by working out, leads to an increase in nuclei, which increases the production of mitochondria. When your fitness regimen falls to the wayside and you decide to re-enter the gym, these gains-based nuclei are already present to quicken muscle cells' adaptation to exercise.

How ALS (Lou Gehrig’s Disease) might work, and what scientists are learning about it

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that affects the nerve cells (neurons) controlling muscle movement. As the motor neurons degenerate, they stop sending signals to the muscles, causing progressive muscle weakness and, eventually, death. This three-minute animation focuses on the mechanisms within the motor neurons that cause them to degenerate. By understanding these mechanisms, researchers hope to one day find a cure for ALS.

'Viscoelasticity' allows muscles to be elongated briefly after stretching

The protective tissues around skeletal muscles consist of elastic proteins like collagen. Stretching them expands their length while retaining strength, ideal for athletes.

Snakes move around by coordinating hundreds of muscles

These muscles connect to their vertebrae, and allow the creature to move in various unique ways. Snakes can slither, move in a straight line, swim, jump and even "fly."

How muscles get their names

There are more than 600 muscles that crisscross the human body, and each has a name that's more than a simple label. Muscle names also typically communicate the muscle's size, behavior, length, location, appearance, direction, and attachments to bone. These names usually have Greek or Latin roots, such as in the case of the deltoid muscles, which are named in reference to the Greek letter delta (𐤃).

Adhesion molecules and intercellular junctions allow cells to connect together

While some organic structures are mostly composed of non-cellular components (e.g., collagen and calcium phosphate minerals in bones), tissues and organs composed of connected cells rely on specialized proteins and connections to create watertight seals that protect cells within the interior from environmental molecules.

What is string theory?

One of the most well-popularized theories about the nature of our universe, string theory attempts to explain fundamental particles and forces by describing them as one-dimensional vibrating strings. The concept remains entirely theoretical, even...

A dispute about the origin of twitching frog legs led to the invention of the first battery

Experiments by Luigi Galvani on exposed frog leg nerves showed activity when they were hung from iron railings and brass hooks, suggesting the existence of "animal electricity" that discharged when connected to metals. Alessandro Volta's voltaic pile, which stacked metals with an inorganic electrolyte, showed that electricity originates from chemical reactions.

Why do dreamers twitch?

This thought-provoking piece highlights newer research suggesting sleep twitches may not be random dream leftovers, but instead a crucial way our brains map and understand our bodies. From sleeping rat pups to dreaming octopi, this biological mapping system appears universal across animal species.

Simulations suggest ice's slipperiness comes from rearranging molecules

Past models have proposed that slipperiness arises from a thin layer of liquid water formed at the ice's surface by frictional melting. However, new research suggests that electromagnetic forces between interacting surfaces push water molecules out of an ordered, crystalline structure and into a shapeless, soft, slippery layer. This process occurs solely through contact, independent of pressure or friction.

The mass of a cell can be measured using hollow, vibrating beams

In 2010, scientists at MIT constructed a U-shaped device that vibrates like a guitar string with an internal fluid channel. As cells and bacteria pass through the device, its rate of vibration shifts, with greater mass creating larger shifts.

Slab pull and ridge push contribute to convection-driven oceanic crust movement

Through ridge push, after magma is projected up from the mantle, it cools and sinks, allowing gravity to help push older oceanic crust away. As this crust sinks into the mantle at deep-sea trenches, it pulls on the trailing crust behind it, accelerating ocean crust movement.

Watch how DNA is packaged to a 10,000th of its original size in a cell

In humans, the 2-meter (6.56-foot) molecule wraps around spool-like proteins called histones, forming beads—nucleosomes—that fold up into fibers. These fibers—chromatin—form loops through folding that compress into larger fibers, which tightly coil together to form a chromosome.

'Artificial embryos': The hidden steps in forming a spine

Somitogenesis is the process by which segmented body structures like vertebrae form in embryos. While the process is well understood in animals like mice or zebrafish it is difficult to study in humans. But now, researchers have created a model of somitogenesis, using pluripotent stem cells, called an axioloid.

The anatomy of 'Mashle,' as described by a doctor

"Mashle: Magic and Muscles" is a manga and anime in which a seemingly magicless man performs outsized feats he blames on "muscle magic." In this 15-minute video, a doctor breaks down the anatomy and biomechanics of some of the feats performed by Mash, the series' main character who's spotted flying a broom via leg pumping and reading magical texts while sitting in an invisible chair (i.e., single-leg squat).

Modern bodybuilding evolved in the 19th century

The origins of modern progressive resistance exercise are traced to ancient Greece, where a repeat Olympic victor carried a calf every day until it grew into a full-sized ox. This 56-minute comedy and history podcast journeys through the rise of modern bodybuilding, which took off during the 19th century.

There are at least 6 fascinating examples of mind-controlling parasites

Parasitic organisms—including flatworms and barnacles, not just fungi—can modify animal behavior. They can give rise to dancing fish, pulsating snails, suicidal rats, and more. Though some of these pathogens can sicken humans, there is no strong evidence that any can control human behavior.

Gladiators fought in specialized armatures designed only for the arena

This illustrated guide breaks down the most common gladiator armatures, showing how each was highly stylized for spectacle rather than warfare. This explanation suggests why gladiators generally made poor soldiers when drafted into the legions.

Newton's laws describe how objects resist acceleration and respond to forces

Newton’s first law defines inertia as the tendency of an object to maintain its velocity. His second law connects external force, inertia, and acceleration, while his third law states that forces come in pairs—every action has an equal and opposite reaction.

Tattoos, explained

Tattoos last because immune cells trap ink beneath the skin—but there's more to the story. This overview looks at how ancient cultures used tattoos for status, spirituality and punishment; how technology like the electric tattoo machine transformed the art form, and where innovations like smart tattoos could take it next.

Learn how your body is, scientifically, like a firework with its own slow, controlled burn.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

While the sun's gravity keeps the planets in orbit, their gravity also pulls on the sun, causing it and everything else in the solar system to orbit around a mutual balance point called the barycenter—the true center of the solar system.

Sony set the standard for cylinder-shaped batteries when it repurposed manufacturing equipment used to make rolls of magnetic recording tape.

How Amazon operates a 'flywheel' business model, a self-reinforcing cycle that drives continuous growth

The concept of phantom limbs, the perception that amputated limbs are still present, dates back to a French military surgeon in the 16th century.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

The word 'jazz' evolved from 'jasm,' 19th-century American slang for 'energy'

The syncytiotrophoblast is the outer layer of the placenta and the largest human cell, spanning an area about twice that of a king-sized bedsheet.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

The animatronic shark from Steven Spielberg's 'Jaws,' the first modern blockbuster, was a complex underwater apparatus called 'Bruce.'

Pure water does not conduct electricity because this flow of energy requires the movement of charged particles, and water is a neutral molecule.

Explore chaos in this simulation of two double pendulums, where small differences in the release angles produce wildly different outcomes.

Gerrymandering works through two techniques: cracking opposing voters across districts to dilute their power, and packing them into a few to waste their votes in lopsided majorities.

SpongeBob exemplifies Aristotle's philosophy for living well because he understands that happiness doesn't come from external factors like money, recognition, or power.

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

'Saturday Night Fever,' the 1977 film that introduced disco to the mainstream, was based on a fabricated magazine story.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

The rivalry between Alexander Hamilton and Thomas Jefferson centered on federalism—the question of how much power the federal government should hold relative to the states.

Long before Major League Baseball began allowing instant replay for balls and strikes, an umpire reluctantly used the technology to determine whether a hit was a home run, a move that inadvertently ushered in a new era for the sport.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.