Some Ozempic users lose their desire to eat

How self-care led to Ozempic's success

Self-care has become a $1.5T economy that idealizes restraint and willpower, leaving behind those who can't shake off human nature. This article explores how Ozempic and similar weight loss medications pick up where self-care left off.

Research suggests Ozempic has benefits beyond weight loss

Semaglutide, the key ingredient in Ozempic, is proving to be more than just a diabetes and weight loss drug. Research suggests it may also help prevent strokes, improve heart health, and slow Alzheimer’s.

GLP-1 drugs mimic a natural hormone that triggers appetite-suppressing effects

Ozempic, one of the brand names for the drug semaglutide, was originally developed in 2012, to help treat Type 2 diabetes. Among other effects, the drug mimics a naturally produced hormone known as GLP-1, which is released while eating to let our bodies know we are full.

The lack of guidance on getting off GLP-1s leaves patients at risk

Dr. David Kessler, former FDA Commissioner and public health leader, explores how these drugs override the brain’s reward-driven eating habits but have notable side effects. These include developing eating disorders, muscle loss, and intestinal obstruction.

Weight loss lessons from 'The Biggest Loser' contestants

This article dives into findings from studies conducted on contestants of "The Biggest Loser" that look at the correlation between weight loss, weight gain, metabolism, and physical activity. The studies support the theory of metabolic adaptation,...

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

Losing a brain-computer interface can trigger lasting psychological distress

A clinical trial participant with severe epilepsy described becoming “one” with her implant after it gave her unprecedented control over her seizures. When the device was removed due to the company shutting down, she experienced deep emotional trauma and a sense of personal loss.

Eating competitions can ruin a stomach's elasticity

Competitive eaters make room for all that food by toying with the stomach's ability to expand and contract. Still, doctors warn that repeated stress can destroy that ability, leading to further issues.

Insurance denials prevent lifesaving care for patients with eating disorders

A patient living with anorexia nervosa was told by her insurance company that she wasn't sick enough to receive needed care. Her experience highlights how some insurers across Washington state focus on less useful metrics like body mass index and weight to gauge sickness instead of psychiatric symptoms that may better illustrate the urgency of receiving care.

Sleep deprivation may slow metabolism

This article explains that, according to research from Penn State, restricting sleep for just a few days can affect how the human body metabolizes fats and change how satisfied people feel after a meal. The study found that people who don’t get...

How the feared self fuels OCD

Obsessive-compulsive disorder is characterized by intrusive thoughts that prompt people to enact compulsions—behaviors intended to relieve the anxiety or stress from the obsession. A significant intrusive thought OCD sufferers endure is the fear they will become a dangerous or immoral person. Therapeutic approaches try to show patients this is just a story that can be set aside.

A Guardian writer turned midlife chess slump into an obsession

Journalist Stephen Moss embarked on a chess self-improvement journey described in "The Guardian." Not a how-to, but a reflection on loss, drive, and whether mastering chess can mean mastering oneself.

Why Smartfood cheddar popcorn lost its flavor

A passionate fan of Smartfood's white cheddar popcorn investigates why the snack's flavor has diminished over the years. After consulting online forums, the author confirmed many fans noticed the shift. The inquiry revealed a major change to the ingredient list between 2019 and 2021, where cheddar cheese was downgraded and "natural flavors" upgraded—likely due to regulations around sodium use in snacks. Read for a fascinating overview of snack formulas, corporate marketing, and more.

TikTok is obsessed with weird cottage cheese recipes

Cottage cheese “cookie dough.” Pizza cottage cheese bowl. Cottage cheese queso dip. TikTok influencers are suddenly posting nonstop cottage cheese recipes. It might be echoes of the 1990s weight-loss obsession, when diet culture encouraged the consumption of questionably tasty low-fat foods and not much else. Now, cottage cheese’s high protein content has made it an intriguing prospect for online fitness gurus who say that it’s the key to building muscle.

Learn about the neuroscience and psychology of why we crave comfort foods

The term was coined in 1966, when psychologist Joyce Brothers suggested humans turn to food associated with the feelings of comfort from their childhoods when experiencing emotional distress. Since then, studies have shown that the familiarity, reliability, and convenience of certain foods from one's upbringing can become tied to feelings of nostalgia.

Is life all about pleasure? Debating the Experience Machine

If you could plug into an Experience Machine that gave you total pleasure all the time, would you do it? Philosopher Robert Nozick thinks you wouldn't, using this as evidence against hedonism, the view that life is all about pleasure. Explore the nuances of the argument and counterarguments with this accessible article.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

During the first Biosphere 2 mission, crew members lost 16% of their body weight

Food and oxygen shortages drove the “Biospherians” to split into two factions—one seeking to bring in outside resources and another aiming to maintain isolation for the experiment’s integrity. Psychological stress was exacerbated further by the increasing prevalence of insect pests.

Anhedonia, which means 'without pleasure' in Greek, is typical in major depressive disorder

This common symptom—a flat affect—results in previously enjoyable hobbies no longer bringing pleasure. People with anhedonia may also avoid social situations because they anticipate they'll bring no joy, not because of anxiety or fear.

The Cincinnati Enquirer's Pulitzer-winning look at the opioid epidemic

Synthetic opioids kill someone in the US every 16 minutes. Communities across the country have been ravaged by deaths, overdoses, jail time, and babies born with drug-related medical problems as opioid abuse became a typical feature of many American towns. This seven-part exposé provides an inside look at the effect in southern Ohio and northern Kentucky.

Cats have a mutation preventing them from tasting sugar

When certain tastes (sweet, umami, bitter) become irrelevant due to a species' diet or lifestyle, the genes for those tastes degrade. In felines, scientists believe a shift to a protein-heavy diet put evolutionary pressure on the genes responsible for tasting sweetness. (Some users may encounter a paywall.)

Many dating app users are beginning to suffer from 'dating app burnout'

For younger generations, dating apps have become a primary avenue for creating romantic connections—leaving some users fatigued and contributing to increased feelings of loneliness.

Two festival-goers were hospitalized after receiving peptide injections, raising questions

Investigative journalism shop ProPublica wrote about two people who became extremely ill following antiaging peptide injections. Authorities were examining whether the individuals were sickened by an infection, contamination related to the injections, or an issue with the medication itself, according to documents obtained by the journalists at ProPublica.

This is what happens to your body during menopause

The menopause transition may begin in one's mid-40s with erratic periods and a decrease in estrogen. It can trigger health complications, including hot flashes, palpitations, and elevated risks of osteoporosis.

The economics of all-you-can-eat buffets

Is it possible to out-eat the price you pay for a buffet? How do these places make money? We looked at the dollars and cents behind the meat and potatoes.

A diary of fasting through all 30 days of Ramadan

Aramco World's first-person account follows one Muslim through a full month of fasting—the pre-dawn suhoor meal, the hunger wall, the social texture of iftar. Get a sense of the day-to-day of Ramadan with this experiential guide.

How one autoimmune disease patient is questing for inflammation cures

This article's writer, who has Hashimoto's Disease and characteristic symptoms from her body attacking her thyroid—like exhaustion, hair loss, and brain fog—shares big take-aways from an anti-inflammatory retreat in Italy. The writer suggests that a holistic approach to eating, sleeping, and stress management, are the only sustainable ways to lower inflammation.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

American short story writer Flannery O'Connor raised 40 peacocks, which became potent symbols for her fiction's elegant violence

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Recent research found that the brain doesn't seem to massively rewire following amputation—upending earlier beliefs about the cause of phantom limb pain.

A vending machine run with Anthropic's AI went out of business after it was convinced to give away items for free and sell a video game console.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

Up to a million Girl Scouts sell about 200 million cookie boxes every spring, generating $800 million, largely because refusing a child is frowned upon

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

In recent years a child anxiety expert has created and tested a novel phobia and anxiety treatment approach for children, focused on changing how parents respond to the fears.

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

Dorothy's famous entrance into Oz in 'The Wizard of Oz' relied on analog tricks, including a body double and sepia-toned paint, as much as it did on technology

Poison ivy is in the same family as mangoes, cashews, and pistachios—and they all produce oily urushiol in their raw, unprocessed state—but they are typically prepared in ways to avoid causing human discomfort.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

Explore the archaeological treasures of Pompeii, the city buried under volcanic ash when Mount Vesuvius erupted in 79 CE.