Cholera went global thanks to global trade

We're in the middle of a decadeslong cholera pandemic

In 1961, the world's seventh recorded cholera pandemic started in South Asia, and it has continued through the decades. India and Bangladesh are at particular risk. This pandemic is driven partly by conflict, population displacement, extreme weather, and poor water infrastructure.

The canal carried germs as well as goods

In 1832, North America’s first cholera epidemic spread inland by way of the Erie Canal, carried by immigrants arriving on ships. Fearful towns barred passengers from disembarking, yet cholera, smallpox, and other diseases still traveled the waterway.

In 1892, two scientists purposefully infected themselves with cholera bacteria

When they became ill—one with mild diarrhea and the other with severe cholera—researchers pointed to that as proof that the pathogen caused the disease.

The cholera bacteria was first isolated in 1854—but the discovery was largely ignored

The pathogen was isolated by the Italian physician Filippo Pacini in Florence, Italy, though his discovery was largely ignored in favor of the popular miasma—bad air—theory of disease at the time. The pathogen was separately isolated about three decades later by German microbiologist Robert Koch.

Measles reached global transmission during the 15th- and 16th-century Columbian exchange

Devastating diseases like smallpox, influenza, measles, and other viruses were largely introduced into the Western Hemisphere beginning with the 1492 arrival of Christopher Columbus and the ensuing age of exploration.

See how cholera spreads in a community

This animated video offers a comprehensive look at how cholera spreads. It makes clear why it's so difficult to stamp out this disease in communities around the world. It also details what steps can help control cholera.

Historically, cholera has repeatedly disrupted the Hajj for Muslims

Outbreaks of the disease throughout the 19th century and the beginning of the 20th, killed thousands of religious pilgrims as they sought to complete this obligatory pilgrimage.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Volcanoes in the 1340s likely helped trigger the Black Death

The "bubonic plague" that wiped out roughly half of Europe and Asia originated from many factors. Recent research suggests volcanic eruptions contributed as well. The "aerosol" effects of matter released from eruptions likely prompted famine and accelerated the spread of infected fleas riding on grains avoiding spoilage.

Cholera was called the 'Blue Death'

In the mid-1800s—when John Snow identified cholera in London—the disease was known simply as the "Blue Death." That's because blood would thicken in patients' veins when they were struggling with extreme dehydration. As a result, their skin would turn a blueish hue as their blood was starved of oxygen.

Climate change is influencing the spread of disease

Rising temperatures and water levels are forcing animals and pathogens beyond their typical boundaries. This article and its data visualizations explore the proliferation of climate-driven diseases.

European colonization contributed to coffee's spread

European colonization created channels for large-scale coffee exports with workforces based in Asia, Latin America and the Caribbean. Trade routes throughout the Middle East and the rest of the world carried the drink to new shores and changed the agricultural and economic landscapes of the countries in the Bean Belt.

Mapping the origins of the world's crops

Food has evolved alongside humanity, and through globalized trade, much of the world can enjoy foods once isolated to one region. Examine where your favorite foods originated from and see how diet differs across cultures with these interactive...

The coronavirus likely came from China’s wet markets

A wet market is a type of marketplace primarily selling fresh, perishable goods such as meat, fish, and produce, often in a non-supermarket environment. The term originated in Singapore during the 1970s, and the "wet" aspect refers to the wet floors resulting from the washing of stalls and the use of ice to keep food fresh. Such markets have been identified as a major source of zoonotic outbreaks, including the COVID-19 pandemic.

Polio commonly spreads when virus-laden feces gets into our mouths

This highly infectious disease is transmitted from one person to another, mainly when we eat virus-laden poop particles. Less frequently, contaminated food or water can transmit the virus, or people can be infected via respiratory droplets (from coughing or sneezing).

Alexander the Great, Rudyard Kipling, and more may have died from food poisoning

Though it is hard to prove decades or centuries after their deaths, some researchers suspect that food poisoning killed a variety of historical figures, including US President Zachary Taylor in 1850: Some researchers believe he may have consumed food contaminated with *Salmonella*.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Neglected tropical diseases affect more people than the population of Europe

This group of conditions, which includes hookworm, sickens roughly one in seven people on the planet—a tally which dwarfs Europe's population of roughly 450 million. International cooperation and donations are helping to control some of these illnesses, which can be caused by parasites, viruses, and bacteria. They're all treatable or preventable, but primarily occur among poor, isolated communities that may not receive adequate care.

How fecal transplants work

1,700 years ago, Chinese alchemist Ge Hong was renowned for his soup that could cure diarrhea-stricken patients. It had a surprising secret ingredient: feces. While it might seem unwise to consume feces, exciting new research suggests that taking...

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

The American cockroach is actually from Africa—an apparent hitchhiker aboard ships carrying enslaved people—with evidence suggesting it may have arrived in the New World as early as the 1600s

This podcast delves into the history of Periplaneta americana and explores why the bugs elicit such fear, disgust, and, at times, shame. The bug likely climbed aboard the slave ships because they had both unprotected food sources and places to hide during their journey.

The Russia-Ukraine war greatly affected the global food supply

Russia's invasion devastated Ukraine's agricultural sector, destroying farms, ports, and grain infrastructure and causing over $40B in losses. Disrupted exports fueled global food insecurity, while Moscow leveraged its grain exports to expand influence across the Global South.

Opium's history traces from religious use to mass-market commercial products

Religious or medical use of opium was present across Europe and Asia as early as 5000 BCE. By the 16th century, humanity had come to see opium as more than medicine: It was a marketable product. This perspective also defines today's relationship with opioids, highly addictive painkillers at the heart of an ongoing drug crisis.

Thomas Cook invented modern tourism

In the mid-1800s, Cook took wealthy Britons on tours of Europe, Africa, the Middle East, and the US, often packaging together transportation, lodging, and food, effectively creating the modern travel agent. He also pioneered travel writing, with “Travellers Handbooks” offering tourists tips for visiting various countries.

British rule in India wasn’t deliberate—it developed from trade

This academic explainer shows how Britain’s rule in India evolved from unplanned trading footholds to complete imperial control. It examines the decline of the Mughal Empire, economic expansion, racism, rebellion, and the mixed legacy of institutions and exploitation that still shape India today.

Global life expectancy has more than doubled since the 1850s

The human species experienced a dramatic increase in expected lifespan over the past 150 years. Antibiotics, improved sanitation, and better worldwide food distribution are a few factors contributing to this rapid transformation. Use this interactive resource to explore longevity gains over time and compare these improvements across the globe.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

Wild chimpanzees have been spotted with leprosy lesions

In research published in 2021, scientists reported discovering cases of leprosy in wild chimpanzees from Guinea-Bissau and the Ivory Coast—marking the first time the disease has been found in any nonhuman species in Africa. They confirmed that leprosy was the cause of the deformities by testing the animals' poop for the presence of the disease-causing bacteria.

Where did zombies come from?

This 17-minute video dives into the origin of modern-day zombies. Zombies can be traced to early West African spiritual practices, specifically Vodou. Vodou evolved from the mixture of beliefs held by enslaved Africans in the French colony of...

Poison ivy was sent to Europe in the 1600s as an exotic, ornamental oddity, where it was purposefully grown in the English royal gardens at Kew, the Faculty of Medicine in Paris, and a few other locations.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

After the Boston Tea Party, colonists switched to coffee, which became the main morning drink for revolutionaries.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

'Shogun,' a 1980s TV series, helped popularize sushi in the US by stimulating an American interest in Japanese culture.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

The term 'algorithm' originated from the Latinized name of al-Khwārizmī, a 9th-century mathematician whose works introduced Arabic numerals and the decimal-based numeral system to Europe and whose treatise 'Al-Jabr' gave algebra its name.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

While El Niño moves warm Pacific Ocean waters east along the equator, La Niña moves them west, shifting where rainfall will become more common for months.

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in casualties, forces mobilized, and displacement of civilians.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

Explore fun facts from the USPS, including unique post office buildings, a stamp that traveled past Pluto, and more.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Fast-casual restaurant Chili's is experiencing a resurgence, with its parent company recently reporting a nearly 32% increase in sales, thanks to passionate Gen Z fans on TikTok.

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.

Electrical grids worldwide must double their power delivery capacity by 2050 to meet surging demand from AI and electric vehicles.

Some researchers have labeled nomophobia, the fear of being without your phone, as 'the phobia of the 21st century.'

In 1963, a basement renovation in Turkey revealed a passageway to a hidden, multilevel underground city that once housed as many as 20,000 people

The most expensive ad of all time was for Chanel No. 5 perfume and cost roughly $33M to produce in 2004—about $57M in today's dollars.