Antimalarials must be taken before traveling to a malaria-endemic area

Anopheles mosquitoes are developing resistance to insecticides

The malaria-transmitting mosquito species is developing resistance to the insecticides used in insecticide-treated bed nets and in indoor spraying in people's homes and communities. Malaria parasites are also developing resistance to antimalarial drugs.

Malaria vaccines are not routine because they have limited effectiveness

Both of the currently recommended malaria vaccines have limited effectiveness, require multiple doses, and provide protection for only a short period of time. One, approved by the World Health Organization in 2021, is only about 30% effective, requires four doses, and protection fades within months. The other requires three shots, and some research indicates it is 75% effective for a year.

Untreated malaria can lead to blocked blood vessels in the brain, coma, and organ failure

Malaria is treatable with medications, but sometimes even after treatment, infection can come back because the disease-causing parasite wasn't completely eliminated. Patients may also have symptoms that emerge years after the initial infection and treatment.

Protecting yourself from West Nile involves avoiding getting bites and clearing standing water

The best prevention against West Nile is avoiding getting bit. That means covering your arms and legs with long, loose-fitting clothes, wearing insect repellant—on top of, not under sunscreen, and making your environment as inhospitable to mosquitoes as possible, including clearing any standing water.

Hear what it's like to have malaria

In Kenya, as one malaria-sufferer explains, the disease is common enough that anytime a child has a fever or any sort of sickness families and the community will wonder if it's malaria. Sleeping under a mosquito net is recommended. Unfortunately, a gin and tonic will not keep malaria at bay.

Malaria comes from the Italian term 'mal'aria,' meaning 'bad air'

The term refers to marshy areas associated with the disease. An estimated 94% of malaria cases—215 million—occur in Africa.

The most severe form of malaria is caused by the Plasmodium falciparum parasite

Multiple species of a single-celled organism called a protozoa cause malaria infection when transmitted by a mosquito bite. But Plasmodium falciparum is the most widespread in Africa, and the most deadly.

Pregnancy makes someone more attractive to the mosquito species that transmits malaria

Research suggests that hormonal levels can affect mosquito attraction. Pregnancy, in particular, is associated with significantly increased interest from Anopheles mosquitoes, which boosts pregnant women's malaria risk.

Wearing tick repellent, covering up, and performing tick checks are the best Lyme prevention

Spraying repellents onto your clothes—and reapplying them—or donning impregnated bug-repelling clothes can help keep ticks away. Effective sprays include DEET, picaridin, or permethrin. Bug spray applied to the body should be applied on top of sunscreen, and only after the sunscreen has dried.

Florida reports 71 imported malaria cases annually—4% of all the US cases

The Sunshine State reports an average of 71 imported malaria cases annually. Malaria isn't endemic to Florida but mosquitoes in the state are biologically capable of transmitting the disease from one infected person to another noninfected person.

Malaria case in Maryland stumped doctors in 2023—leading to the wrong treatment

When the state had its first locally acquired malaria case in over 40 years, the patient was misdiagnosed with a more common tick-borne infection, leading to weeks-long treatment for the wrong infection. The patient had symptoms that could occur with malaria or with babesiosis, a disease caused by Babesia parasites and transmitted by ticks in the US.

See this diverse list of vector-borne diseases

Human illnesses caused by parasites, viruses, and bacteria, and transmitted by a living organism—often small, bloodsucking ones like mosquitoes, ticks, and sandflies—are known as vector-borne diseases. That carrier is called a vector. These diseases disproportionately affect the poorest populations in tropical and subtropical areas.

The mosquito's role in the transmission of malaria was confirmed in 1897

The British army doctor Ronald Ross, who later won the Nobel Prize for his work, was the first to describe the transmission of malarial parasites by mosquitoes. He had lab mosquitoes suck blood from malaria-infected people and separately found the malaria parasite inside a mosquito's gut, confirming the bug's role in malaria transmission.

'Sloth fever' is an emerging health threat, especially to pregnant women

This disease, caused by the Oropouche virus, is found in animals including sloths, primates, and birds. It primarily spreads through the bite of midges—insects commonly called "no-see-ums." It's endemic to the Amazon region, but US travelers are increasingly contracting it internationally.

See the geographic spread and incidence of malaria

This graphic shows the estimated global burden of malaria in 2025 as new cases per 1000 people at risk.

Disney World is largely mosquito-free, thanks to civil engineer Joe Potter

As a former governor of the mosquito-prone Panama Canal zone, Potter understood the danger of standing water. At Disney, Potter built ditches to reduce moisture, designed buildings to channel water away, and more. His efforts help visitors avoid bites, adding to the perceived magic of the magical kingdom.

The most effective method of managing invasive species is prevention education

Controlling a spread after a species has become established in an area is much more costly and time-consuming than early detection and rapid response. Control methods include the purposeful introduction of predators, the use of pesticides, herbicides, fungicides, and insecticides, and physical collection and removal.

Tips for reducing the risk of antimicrobial resistance

Antimicrobial resistance is bad news. But there are lots of things you can do to both protect yourself from superbugs and help keep the problem of antimicrobial resistance from getting worse. This page from the CDC offers clear, straightforward guidelines that can help keep you—and your loved ones—healthy.

Eating street food while traveling isn’t recommended, but there are ways to do it more safely

The US Centers for Disease Control and Prevention urge people to stay away from street food while traveling. But if you still want to eat it, the agency recommends making sure it’s cooked food and that it’s served steaming hot. Also, avoid eating any raw vegetables as they may be more likely to harbor pathogens.

MS risk is shaped by geography, not just genes

Latitude—and related vitamin D exposure—seems to affect MS risk. People who migrate from a high-risk MS latitude (like northern Europe or the northern US) to a lower-risk latitude (like tropical areas) before age 15 tend to adopt the lower risk of their new country—suggesting there's a critical window for environmental exposure.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients.

Watch the cumbersome, but necessary, precautions healthcare workers must take to care for and protect themselves while caring for Ebola patients

Treating someone with Ebola involves a painstaking process of suiting up (donning) and peeling off (doffing) protective gear. Doctors follow detailed CDC guidelines. Properly suiting up is key to protecting against fluids that transmit Ebola, and correctly removing a suit that could be contaminated with the virus is also critical.

Drug trafficking in the MENA

The Middle East and North Africa is a major source, transit point, and consumer of illicit drugs. Despite having some of the harshest penalties for drug-related crimes, the region both influences and is negatively impacted by illicit substance abuse...

Certain medications that affect blood flow or mood boost the risk of heatstroke

Drugs that narrow blood vessels, beta blockers that regulate blood pressure, diuretics, antidepressants, and antipsychotics can all affect the body's ability to regulate its internal body temperature, and so individuals taking these medications need to take special care in extreme heat and when exercising in hot conditions.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

Your device can become infected with malware by simply browsing the internet

During a drive-by download attack, security flaws in a program or operating system (e.g., Windows) used to access online content are exploited, and malicious code is downloaded—for example, when loading a hacked webpage—onto a user's device without their knowledge. Restricting internet browsing to safe sites and installing security updates helps prevent these attacks.

Bupropion is the only antidepressant approved for the preventive treatment of SAD

Clinical trials showed a 44% reduction in risk for recurrence of SAD for those who took the drug compared to a placebo group. Bupropion is a norepinephrine–dopamine reuptake inhibitor, which increases dopamine (other common antidepressants, known as selective serotonin reuptake inhibitors, sometimes can suppress dopamine, but not always).

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Poison ivy is in the same family as mangoes, cashews, and pistachios—and they all produce oily urushiol in their raw, unprocessed state—but they are typically prepared in ways to avoid causing human discomfort.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

Power lines are dotted with large, brightly colored balls to improve the visibility of these thin wires to helicopters and small planes and help prevent potential crashes.

Hotels in Cannes, the glamorous city on the French Riviera, hire hawks to ward off seagulls during the city's famous film festival.

Coral reefs get their colors from zooxanthellae—microorganisms that line corals' digestive tracts and provide them with sugars in exchange for a home within this protective tissue.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Lesser-known phobias include turophobia, or the fear of cheese, and nomophobia, the fear of being without your cell phone.

To reduce wrinkles in clothing, research recommends gentle wash cycles with more water and tumble drying with smaller loads and longer times.

Take a 3D tour of the Hajj, Islam's annual pilgrimage to Mecca, undertaken by more than 1.5 million Muslims each year.

Abraham Lincoln was almost assassinated weeks before his inauguration as he traveled from Illinois to DC through Baltimore in 1861; it took two independent claims for Lincoln to be convinced the threat was real

The US first hosted the World Cup in 1994, a tournament that lives in soccer infamy for its poor planning and the murder of Colombian player Andres Escobar, who'd accidentally scored on his own net.

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

While El Niño moves warm Pacific Ocean waters east along the equator, La Niña moves them west, shifting where rainfall will become more common for months.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

For centuries, it was common to sleep in two shifts: a few hours at the beginning of the night, and a longer period beginning around midnight

See this overview of the firework rules across all 50 states, ranging from a complete ban on non-professional fireworks in Massachusetts to states with more lax rules like Indiana.

A 2019 Facebook event called on attendees to "Storm Area 51, They Can't Stop All of Us," resulting in countless memes, the creation of a music festival, and eventually the arrests of those who did try to approach the area.

Art theft is the third-largest source of criminal revenues worldwide, thanks in part to the subjective nature of valuing a work of art.

Explore fun facts from the USPS, including unique post office buildings, a stamp that traveled past Pluto, and more.