See this diverse list of vector-borne diseases

Vector-borne diseases kill more than 700,000 people globally each year—and are growing

The diseases with the greatest potential to spread widely aren't the ones that quickly kill human hosts. Instead, the best hosts or reservoirs for vector-borne diseases would be chronically ill over the long term, increasing the likelihood that the pathogen could be transmitted to others.

Lyme disease is the most common vector-borne illness in the US

In the US, ticks account for 90% of all disease transmission from bites, including mosquitoes. And Lyme disease is the most common vector-borne disease in the US overall, with estimates suggesting there are about 475,000 Lyme cases annually across the nation.

Zoonotic diseases: Pathogens that jump from animals to humans

Such diseases may be caused by a variety of pathogens—viruses, bacteria, fungi, or parasites—and can originate in creatures ranging from ticks and mosquitoes to pigs and bats. Because they develop in animals and are often new to human immune systems, zoonotic diseases have severe consequences for public health.

Neglected tropical diseases affect more people than the population of Europe

This group of conditions, which includes hookworm, sickens roughly one in seven people on the planet—a tally which dwarfs Europe's population of roughly 450 million. International cooperation and donations are helping to control some of these illnesses, which can be caused by parasites, viruses, and bacteria. They're all treatable or preventable, but primarily occur among poor, isolated communities that may not receive adequate care.

Bats are uniquely suited to act as reservoirs of viruses

Some of the deadliest diseases to jump from animals to humans originate in bat species. This rich visualization explores the diversity of bats and the factors that make them efficient vectors for harboring and transmitting disease, from their long lifespans to their migration patterns.

Treating black fever can result in a complication that spreads the deadly disease

Black fever, a deadly parasitic disease second only to malaria, threatens more than 1 billion people across more than 83 countries. Also known as kala-azar or visceral leishmaniasis, the disease is caused by parasites that spread through sandfly...

The 'kissing bug disease' occurs when a bug's parasite-laden poop gets into your blood

Chagas disease transmission can occur when triatomine bugs bite someone infected with a Trypanosoma cruzi parasite and then bite someone else, passing on the pathogen, though the parasite can also be transmitted in other ways, including via food, congenitally, and through blood transfusions. The bugs tend to feed at night and can bite anywhere on the body, but their reputation for biting people around the mouth and eyes created the idea that the bugs were "kissing" humans. Recent research suggests the disease may be endemic in the US.

Some mosquitoes are key pollinators—and eat disease-carrying mosquitoes

​​There are more than 3,500 species of mosquitoes, and only a small fraction of them bite humans. They also play vital roles in the ecosystem: One young elephant mosquito, for example, can eat dozens of smaller mosquitoes that bite humans in just one day. Sometimes mosquito-gobbling species are released by humans to control other mosquitoes.

Mosquitoes top the ranking of the world's deadliest animals

Mosquitos kill about 760,000 people every year. The vast majority of those deaths are caused by malaria, which is transmitted and spread by the Anopheles mosquito. The second-place deadliest animal title goes to snakes, with an estimated human death toll of around 100,000 annually.

From 1970 to 2017, invasive species have caused $1.28T in damage globally

The costliest species were the Asian tiger and yellow fever mosquitoes ($149B), which arrived in the US from Asia and sub-Saharan Africa, respectively. The bulk of their damage came from their transmission of diseases such as Zika, chikungunya, and dengue. (Some readers may experience a paywall.)

See this graphic of the complex malaria transmission lifecycle

Female Anopheles mosquitoes contract malaria by feeding on the blood of a human already infected with the disease-causing parasite. The parasite then develops in the mosquito's gut for one to two weeks before it migrates to the mosquito's salivary glands. Next, when the mosquito bites another person the parasite is delivered into the bloodstream of another human. This graphic further details what happens inside the human body during infection.

West Nile Virus is maintained in nature, even without human infections

Mosquitoes pick up the virus when they feed on birds, and then pass it to other birds with their bite, delivering it via virus-laden saliva. Hundreds of different North American bird species can harbor the virus—even if they don't all get sick from it.

Mosquito-borne illnesses have killed captive orcas at SeaWorld

After two SeaWorld orcas died from viruses carried by mosquitoes, scientists warn that mosquito-borne illnesses may be a bigger threat to these captive animals than previously known. Captive orcas spend a lot of time stationary, close to the surface, unlike their wild counterparts. Researchers saw mosquitoes landing on the animals' backs, heads, and dorsal fins, supping on their blood.

'Sloth fever' is an emerging health threat, especially to pregnant women

This disease, caused by the Oropouche virus, is found in animals including sloths, primates, and birds. It primarily spreads through the bite of midges—insects commonly called "no-see-ums." It's endemic to the Amazon region, but US travelers are increasingly contracting it internationally.

Yes, many animals get malaria—not just humans

Birds, rodents, monkeys, lizards, bats, apes, and livestock are among the species that can become infected with malaria. Infected animals' symptoms often resemble those of humans, including fever, lethargy, loss of appetite and difficulty breathing. Birds will also have ruffled feathers and drooped heads.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

Wolbachia is a naturally occurring bacterium being employed to fight dengue

Scientists are fighting dengue spread in a roundabout way: injecting bacteria into Aedes aegypti mosquito eggs, which blocks the dengue virus from replicating in the tissue of mosquitoes. Researchers hope the bacterium will be passed to future generations, inoculating them against dengue. Wolbachia is also being investigated to combat other mosquito-borne diseases.

Every virus is classified into 7 groups based on genetic differences

Viruses infecting humans have been named based on symptoms ("chickenpox") or the location or animal in which they were first discovered ("Bolivian Haemorrhagic Fever" and "Monkeypox"). For clarity among scientists and to reduce stigma, virologists classify the 15,000 known viruses (270 of which infect humans) by their basic genetic material.

Dengue is sometimes called 'breakbone fever' because it's so painful

Though this mosquito-transmitted disease can be asymptomatic, in more severe cases patients experience high fever, muscle spasms, and joint pain. The experience can be so excruciating that it feels like the patient's bones are broken, thus the nickname of breakbone fever. It's the world's fastest spreading tropical disease.

There are at least 6 fascinating examples of mind-controlling parasites

Parasitic organisms—including flatworms and barnacles, not just fungi—can modify animal behavior. They can give rise to dancing fish, pulsating snails, suicidal rats, and more. Though some of these pathogens can sicken humans, there is no strong evidence that any can control human behavior.

Zika virus shocked scientists because the mosquito-borne disease causes birth defects

This revelation, confirmed in 2016, marked the first time that a mosquito-borne disease was known to cause birth defects. Fetuses exposed to the Zika virus during pregnancy sometimes suffer from neurological complications and microcephaly, a small-headed condition associated with neurological development issues and impairment.

See how the Ebola virus affects blood circulation in the human body

Ebola infects and disables immune cells, causing a cascade of events that result in small blood clots throughout the body, weakening blood vessels, and interrupting blood flow to key organs.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

Measles reached global transmission during the 15th- and 16th-century Columbian exchange

Devastating diseases like smallpox, influenza, measles, and other viruses were largely introduced into the Western Hemisphere beginning with the 1492 arrival of Christopher Columbus and the ensuing age of exploration.

View a list of simple ways you can avoid catching a computer virus

Because this type of malware requires human intervention, such as plugging an infected flash drive into a computer or downloading and running an infected file, the chance of infection can be greatly reduced by being cautious about unfamiliar emails, attachments, and links. Keeping systems up to date with the latest security fixes is also crucial.

The history of germ theory, which explains that illnesses are caused by microorganisms

For centuries, the miasma theory, which held that illnesses were caused by clouds of "bad air" produced by decaying organic matter, was the accepted explanation for the spread of disease. The development of microscopes and the subsequent technology to isolate bacteria and test disease spread in mice greatly contributed to contagionists overturning miasmatists.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

What is cardiovascular disease?

Cardiovascular diseases are a range of related health conditions that develop in the heart and blood vessels. This article and related infographics detail cardiovascular disease types and treatments.

Ebola species have historically been named after where they were discovered, stigmatizing residents who live there, including Bundibugyo, in Uganda.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

Experimental hantavirus vaccines and therapies, still under development, have long been funded by the US military.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

Poison ivy is in the same family as mangoes, cashews, and pistachios—and they all produce oily urushiol in their raw, unprocessed state—but they are typically prepared in ways to avoid causing human discomfort.

See how each of the more than two million known species relates to each other—and to common ancestors—in this zoomable tree of life.

Lesser-known phobias include turophobia, or the fear of cheese, and nomophobia, the fear of being without your cell phone.

Planarian flatworms are small, aquatic worms with exceptional regenerative capabilities. When cut, the worms can regenerate multiple bodies in a matter of weeks.

View the ten deadliest tornadoes in US history.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Explore an interactive map built from more than 100,000 survey responses on where people find joy in their lives

All rainbows are 'raincircles' caused by water droplets separating white sunlight into a spectrum of colors, but Earth's surface blocks the bottom half of the circle from our line of sight.

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in casualties, forces mobilized, and displacement of civilians.

The tragic Pulitzer Prize-winning image 'The Vulture and the Little Girl' (1993) generated controversy, raised concerns about ethics in photography, and eventually led to the photographer's death.

The United States is one of only around two dozen countries with a fully federal system of government, in which power is divided between national and state governments.