Beyond DNA, Franklin's legacy extends into modern virology and steel production

Rosalind Franklin’s work led to Nobel Prize-winning discoveries in DNA and virology

Her X-ray diffraction imaging helped uncover the structure of DNA, which earned James Watson, Francis Crick, and Maurice Wilkins a Nobel Prize. The same techniques enabled virus imaging, contributing to Aaron Klug's Nobel Prize in chemistry.

The woman erased from the DNA breakthrough

Rosalind Franklin captured “Photo 51,” the key to DNA’s double helix. Her data, shared without her knowledge, helped Watson and Crick win a Nobel. She never got the prize, but today, her role in unlocking life’s blueprint is finally recognized.

Rosalind Franklin uncovered the molecular structure of the tobacco mosaic virus

Franklin's work revealed the role of ribonucleic acid in virus infectivity, contributing to a foundational understanding of genetics and virology. Her molecular model of the virus was featured as the centerpiece at the 1958 Brussels World's Fair.

Rosalind Franklin was the long-overlooked contributor to discovering DNA's structure

Though James Watson, Francis Crick, and Maurice Wilkins are credited with discovering the DNA double helix, it incorporated Rosalind Franklin's unpublished data. Photo 51, her famous DNA image, took more than 100 hours to produce and a year’s worth of analysis to interpret.

English chemist Rosalind Franklin (1920 - 1958) on the importance of science

"Science and everyday life cannot and should not be separated. Science, for me, gives a partial explanation of life."

Watson's book was described as misleading when detailing Franklin's role in DNA

Despite working together to win the Nobel Prize for their discovery of the structure of DNA, Francis Crick and Maurice Wilkins objected to the publication of James Watson's account of DNA's discovery. Those involved describe how he villainized Rosalind Franklin and downplayed her work.

Exploring carbon compound pore structures contributed to improved gas mask filtration

During World War II, the British Coal Utilisation Research Association sought to improve the efficiency of coal as an energy source and studied the effectiveness of charcoal filters to keep soldiers safe. Rosalind Franklin's research there formed the basis of her PhD and led to five scientific papers.

Oxford scientists turned Fleming’s mold discovery into medicine

In 1939, a team at Oxford—including Howard Florey, Ernst Chain, and Norman Heatley—revived Fleming’s forgotten discovery. Using makeshift equipment like bedpans and milk churns, they purified enough penicillin to prove it could treat deadly infections.

Bacteria helped scientists realize that DNA was the hereditary molecule, not proteins

Until the mid-1900s, most scientists believed genes were made of proteins, which were known to act as enzymes, hormones, and other chemicals that mediated an organism's traits. The Avery-MacLeod-McCarty and that benign bacteria could be made lethal, where the inherited factor that caused bacterial transformation contained DNA.

View a collection of historical documents about molecular biology's history

The collection features materials related to those involved in the discovery of DNA and provides historical context for the discoveries of RNA, various viruses, and important bioproteins. The items include photographs, business correspondence, manuscripts, and scientific instruments.

Watch how Sanger sequencing kickstarted the first generation of DNA sequencing

Sanger sequencing is a foundational DNA sequencing technology developed in 1977. The Nobel Prize-winning discovery uses fluorescent dyes at the end of DNA chains, which are sorted by length through electrophoresis, to determine the order of nucleotide bases.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Despite privacy risks, scientists are using DNA in the air to assess ecosystem health

While DNA in soil and water samples has long been used for such analyses, airborne DNA is being incorporated into such efforts to monitor individual species abundance, detect invasive species, measure biodiversity, and determine the success of conservation actions. Future work may include detecting attacks from biological weapons.

Dr. Bernard Fisher pioneered lumpectomy as a treatment for breast cancer

Dr. Bernard Fisher was a surgeon-scientist who developed and discovered cancer treatments that changed the way we treat and understand breast cancer. Despite these contributions, Fisher was also the subject of a congressional investigation that tarnished his reputation. Listen to the "Less Radical" six-episode podcast series covering the complex story of this influential doctor.

The first line of 'immortal' human cells, which can divide indefinitely and are used in scientific research, was nonconsensually taken from a Black woman.

Marie Curie's work with radioactive materials left traces on her furniture and notes

Some of Marie Curie's family heirlooms were radioactive and destroyed. Marie and Pierre Curie are entombed in lead coffins to block radiation.

Learn the history of food science breakthroughs from the 20th century

Long after humans developed the means to produce sufficient food to feed civilizations, scientific research focused on a wide variety of objectives, such as developing methods to preserve food quality (accomplished via frozen food), speeding up cooking (leading to the microwave), and lowering the cost of sweetening food, which high fructose corn syrup provides.

Benjamin Franklin donated the books that became the first true public library in the US

In 1778, the town of Franklin, Massachusetts—named in his honor—asked Benjamin Franklin for a bell, but he donated a book collection instead, saying "sense" was more important than "sound." Residents voted in 1790 to make the books freely available to all, creating the nation's first public library.

Mitochondria—only inherited from mothers in most animals—have their own DNA

Mitochondrial DNA, or mtDNA, typically takes the shape of a circle and contains genes that code for proteins essential to the production of energy-containing molecules called ATP. When mitochondria fuse, the mixing of healthy and damaged mtDNA helps alleviate the effects of mutations that may have occurred during mitochondrial division or environmental interactions.

Einstein warned the president that splitting atoms could lead to powerful bombs

In a 1939 letter to Franklin D. Roosevelt, Albert Einstein explained that nuclear fission could produce immense energy—and devastating weapons. The warning helped spur the Manhattan Project, a role Einstein later deeply regretted.

Eleanor and Franklin Roosevelt were 5th cousins, once removed

This means the couple shared great-great-great-great-grandparents but from different generations of the same family line. Fifth cousins are considered distant relatives, with only a 10% to 15% chance of sharing detectable DNA.

'Our greatest responsibility is to be good ancestors.'

- Polio vaccine developer Jonas Salk (1914–1995)

The history of Vannevar Bush, who influenced the creation of hyperlinks and the NSF

As director of the Office of Scientific Research and Development, Bush submitted a report outlining how to support basic research at American colleges and universities by establishing an independent funding agency, which laid the groundwork for the National Science Foundation. His idea for a Memex machine that connected microfilm content in "associative trails" of links would influence Douglas Engelbart's development of hypertext.

Computer pioneer Alan Turing was also an elite runner

Alan Turing is credited with helping to found modern computer science, in addition to cracking the Nazi code known as Enigma. Beyond these world-historical achievements, the British mathematician also nearly represented his country in the Olympics in the marathon, running just 11 minutes slower than the eventual gold recipient at the 1948 games. Read more on this lesser-known aspect of the man here.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

Several birthstones play key roles across modern technologies

Diamonds are used in drills and quantum computing, while peridot and zircon help in steelmaking and carbon capture. Rubies, sapphires, and alexandrite enable several varieties of lasers found in medicine and advanced optics. Garnets are found in water filtration systems and radiation detectors. Sapphires are used as substrates in semiconductors.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

‘Frankenstein’ is a classic horror novel

Few novels have been as influential as Mary Shelley’s “Frankenstein.” The 1818 novel is considered the first science fiction novel and a cornerstone of the horror genre. The text has also been widely adapted for the screen and is responsible for at least two major archetypes: the creature and the mad scientist.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

Against his wishes, Albert Einstein's brain was removed before his cremation, and the pathologist responsible stored it for decades in mason jars within a beer cooler.

Radioactive elements can introduce software errors because the ionizing radiation they produce can detach electrons from atoms, and computer code relies on the distribution of electrons.

English mathematician Ada Lovelace wrote the first computer algorithm a century before computers existed and hypothesized that computing devices would one day be able to compose music—foreseeing the generative AI systems of today.

The name 'Silicon Valley' arose from the founding of Shockley Semiconductor Laboratory in Fairchild Semiconductor in 1956-57, founded near Stanford University in Palo Alto

Warren Buffett's former professor Benjamin Graham is known as the 'father of value investing,' a strategy in which investors seek to buy stocks trading below their intrinsic worth.

How fusion—which releases energy when two lighter atoms combine to form a heavier atom—differs from fission

The story of Dollree Mapp, whose legal challenge over her 1957 conviction for possessing "obscene material" led to a major strengthening of the Fourth Amendment

The Mona Lisa's celebrity status and repeated restorations have obscured what made the painting so revolutionary for its time

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

During the French Revolution, a botanist's letter asking about "dear Rhus" (poison ivy) was intercepted, leading authorities to suspect he was conspiring with the Russians.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

Legendary architect Frank Lloyd Wright designed the SC Johnson headquarters in Wisconsin, aiming to make a cathedral-like workplace

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Hear 50 years of iconic hip-hop samples, the genre's foundational looped tracks

American dance legend Martha Graham, sometimes called 'the Picasso of dance,' refused to perform at the 1936 Olympics in Berlin and conceived the piece 'Chronicle' in response to the experience.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

The US Constitution is widely regarded as the longest-standing written national constitution still in force—see how it has influenced rights worldwide.

Explore fun facts from the USPS, including unique post office buildings, a stamp that traveled past Pluto, and more.

Sony set the standard for cylinder-shaped batteries when it repurposed manufacturing equipment used to make rolls of magnetic recording tape.