One person dies from opioids every 7 to 8 minutes

The three waves of the opioid crisis: overprescription, heroin, and fentanyl

The US opioid crisis has unfurled in three distinct waves, each spiraling into an epidemic that's killed millions. The first crested in the 1990s with the overprescription of opioids for pain relief. The second manifested as heroin overdoses in the 2010s. The third began in 2013 with the rise of deaths related to tramadol and fentanyl.

From prescriptions to street drugs: Opioids trajectory across America

Exclusive data obtained by The Washington Post from the Centers for Disease Control and Prevention shows how individual counties moved through three waves of the opioid crisis, each wave paving the way for the next. Between 2011 and 2017, the drug responsible for the majority of overdose deaths shifted from prescription pills to heroin to fentanyl. Together, oxycodone, hydrocodone, heroin, and fentanyl have been major drivers in declining life expectancy in the US.

The Cincinnati Enquirer's Pulitzer-winning look at the opioid epidemic

Synthetic opioids kill someone in the US every 16 minutes. Communities across the country have been ravaged by deaths, overdoses, jail time, and babies born with drug-related medical problems as opioid abuse became a typical feature of many American towns. This seven-part exposé provides an inside look at the effect in southern Ohio and northern Kentucky.

Synthetic opioids: a historical and clinical review

In the 19th century, researchers began synthesizing and isolating poppy plant alkaloids, leading to the invention of morphine, codeine, heroin, oxycodone, and others. These highly addictive variants eventually gave rise to illicit use and a widespread underground market, laying the foundation for the current opioid crisis.

Learn about the US opioid crisis in this free course

Where did the US opioid crisis come from, and how did it spread? Learn this and more in this free, online Harvard University course. Learn about the disease model of addiction treatment and management, and get up-to-date with public health and law enforcement's current harm reduction practices. This free resource gives users a greater understanding of opioid addiction and the epidemic still haunting the US.

Opioid epidemic 101: lawsuits and settlements

State and local governments trying to address the opioid epidemic have sued organizations they believe started and supported the crisis. Companies that made, distributed, or contributed to sales of the highly addictive painkillers are expected to pay more than $50B in settlements. These settlements specifically state that at least 85% of settlement funds must be spent on addressing the epidemic, though where exactly the money is going is unclear.

Opioids mimic naturally produced endorphins to dull pain

Once in the body, opioids bind to naturally occurring opioid receptors typically used by endorphins to temper pain. They trigger the release of dopamine, a desire-related hormone, and decrease noradrenaline, a neurotransmitter involved in heart and breathing rate regulation, meaning high doses can slow these processes to dangerous levels.

Overwork contributes to thousands of worker deaths

Can work really kill you? The World Health Organization and the International Labor Organization have estimated that long work hours contribute to thousands of death from strokes and heart attacks each year. This BBC article argues that the culture of overwork and burnout is leading to a public health crisis in desperate need of solutions.

Infographics explaining global terrorism trends

Our World in Data’s terrorism page details global trends in terrorism. Through interactive infographics, the site shows how the number of terrorist acts varies around the world and how it has changed over time. Sections investigate common definitions of terrorism, trends in global terrorism deaths, and the global distribution of terrorism. Additional segments highlight airline hijackings, public opinion, and media coverage of terrorism. Explore this website for an array of infographics on terrorism.

Drug-resistant infections worldwide have increased by about 65% since 2000

Since 1990, antibiotic resistance has claimed at least one million lives annually and is projected to account for 39 million deaths between now and 2050 if current trends continue. The expanded use of antibiotics, particularly in agriculture, combined with a slowing pipeline of new drugs has led to the crisis.

The National Institute on Drug Abuse's resource library

The National Institute on Drug Abuse website is an in-depth and highly prolific resource on addiction science. Explore the vast scope of this website to access comprehensive guides, data visualizations, and educational materials on all facets of addiction and its treatment.

See the data comparing healthcare worker violence with other industries pre-pandemic

Nonfatal workplace violence against healthcare workers steadily climbed each year even before the pandemic. Healthcare workers comprised 73% of all nonfatal workplace injuries and illnesses due to violence in 2018. The violence was highest among psychiatric and substance abuse hospitals.

11 people died from firework injuries in the US in 2024

Most of those deaths involved misuse of the explosives and device malfunctions or misfires. That fatality count doesn't include the almost 15,000 people who received treatment in the emergency room due to firework-related injuries. More than a third of all the injuries in 2024 were burns, underscoring the risks of using these explosive devices.

Most Americans are now dying at home, reversing 20th century trends

For most of the 21st and 20th centuries most Americans died in hospital settings. But in 2016, home-based deaths overtook hospitals; most Americans are now dying at home, likely fueled by individual preferences to die at home or to receive at-home palliative care.

Someone suffers from a stroke every 40 seconds

Every 40 seconds, someone in the US experiences a stroke—and every minute without treatment destroys millions of brain cells. This explainer breaks down the two main types of strokes, their risk factors, and how early detection could change outcomes in the future.

11 people died from firework injuries in the US in 2024.

About 10%-15% of people experience chronic insomnia

How often would you say you struggle to stay or fall asleep? If it's more than three times per week (and has been going on for at least one month), then you might have one of the most common sleep disorders: insomnia.

How Kurt Cobain's suicide changed the media

Public health experts feared that the suicide of a high-profile figure, especially for young people, would lead to a rise in suicides across the country. The opposite turned out to be true: Suicide rates decreased. Specialists suggest that's due to the way Cobain's death was covered, with news organizations largely avoiding glorification and including crisis hotline information.

Calculate your risk of developing cancer

Hosted by the National Cancer Institute, this tool provides interactive charts that display the likelihood of dying from various causes—including cancer—based on factors like age, sex, race, and smoking status. By contextualizing cancer risk among other potential health threats, users can create custom charts.

See Virginia's emergency stats broken down by date, type, and even body part

This dashboard from Virginia's health department provides a detailed look at various aspects of its emergency care services from January 2019 to December 2024, when there were more than 575,000 emergency incidents. More than 40% of its emergency services were devoted to slips and falls.

What can psychedelics teach us about dying?

Psychedelics have made their way into the world of licensed mental healthcare, and the drugs have been proven to help people process and lessen anxiety and depression. What does this mean for people with terminal illnesses who are afraid of death?

The popularity of new weight loss drugs has led to a diabetes treatment shortage

The FDA approved Ozempic to help patients with diabetes, but the popularity of semaglutide as a weight loss drug led doctors to prescribe Ozempic to nondiabetic patients who needed to lose weight. Ozempic became so popular that manufacturers could not keep pace with demand, posing risks for Ozempic-users with diabetes.

1 in 10 US adults are taking medication for depression

A US government report indicates that about 10% of US adults took prescription medication for this disorder in 2023. Women, at 15.3%, were more than twice as likely to take one of these medications than the 7.4% of men.

Indigenous women are murdered at 10 times the rate of all other ethnicities in the US

Murder is the third-leading cause of death among Indigenous women, who are also 2.5 times more likely to experience violence than any other group. More than 4 in 5 Indigenous women have experienced violence in their lifetime.

The latest data on US motherhood

Here’s a snapshot of what motherhood looks like in the U.S. today, drawn from government data and Pew Research Center surveys. The list includes seven headline statistics with visual graphs, including the average age of a mother's first childbirth...

Influenza infects up to a billion people worldwide each year

The World Health Organization estimates that seasonal influenza causes about 1B cases annually, including 3 to 5M severe illnesses and between 290,000 to 650,000 deaths.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

Roughly 43 million US borrowers owe roughly $1.7T in student debt, the second-largest source of consumer debt behind mortgages.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

A century of Billboard issues documenting the evolution of popular music.

Some researchers have labeled nomophobia, the fear of being without your phone, as 'the phobia of the 21st century.'

The price of gas is a composite made up of several different factors, with the federal gas tax making up less than 20% of what drivers pay at the pump.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

The Nasdaq's 'Magnificent 7' companies are responsible for roughly 40% of the Nasdaq 100 index's gains, while the remaining 93 companies account for the other 60%.

About 2,000 US babies are born annually without some portion of their limbs, potentially leading to a lifetime of pricey prosthetics.

See 33 images that became central to huge scandals, including a young Charles and Camilla, Michael Jackson's baby on a hotel balcony, and Hugh Grant's mugshot.

Learn how monoclonal antibodies, which mimic the body's antibodies, can fight diseases like Ebola.

Poison ivy's rash-causing compound is found in the plant's roots, stem, and leaves—so coming into contact with any part of the plant can lead to rashes for the 85% of people who are allergic to it.

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in casualties, forces mobilized, and displacement of civilians.

44% of Americans say they pray at least once a day—discover how your state's religiosity stacks up against the rest of the country.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.

As of 2025, the most cited papers in science include a review of graphene, methods to improve image recognition, streamlining electron density calculations, and optimizing protein studies.

According to the physics of black holes, our 4D reality may be a hologram—a projection of information coded on a 2D surface on the edge of the universe.

Memecoins are a type of cryptocurrency—a form of digital currency with a wide variety of uses—created around popular 'memes,' or viral internet jokes.

Explore the known asteroids, comets, and spacecraft involved in asteroid studies within our solar system with 'Eyes on Asteroids,' a 3D visualization from NASA.

Volcanoes 'die' when their supply of magma runs out, if they are shifted away from their underlying magma reservoir, or if they get clogged by collapsing or their magma cooling back into rock.

An initial public offering or 'IPO' is the process of a private company becoming public by putting shares of the company on the stock market for purchase.