New drugs called Gepants have been shown to improve the quality of life of many sufferers.

Migrane 101: data, symptoms, and treatments

Living with migraine, however often the neurological condition attacks, is a journey fraught with pain and isolation. This migraine guide offers insight into the condition, common triggers, possible treatments, personal stories, and tips for managing life with migraine.

Headache disorders have historically been neglected and under-researched

Confusion between the variety of headaches—from mild discomfort to debilitating pain—and gender bias—migraines primarily affect women—have led to widespread misunderstandings of the medical issue. Medical students in the US may get as little as 30 minutes of instruction on the three major types: migraines, cluster headaches, and tension-type headaches.

Why say 'migraine' instead of 'migraines'?

Language choice can affect people's assumptions and beliefs about the subject at hand, which is why some would prefer "migraine" to be treated as a singular and plural noun. This American Migraine Foundation article examines the logic behind the grammar choice.

Historians theorize Vincent Van Gogh suffered from Ménière's disease or epilepsy

A century after researchers suggested he suffered from epilepsy, some researchers in the 1990s began to support an alternate diagnosis: Ménière's disease, since he had suffered from severe, repeated attacks of disabling vertigo. Still, some researchers remain skeptical of the Ménière's diagnosis. One posits that Van Gogh had temporal epilepsy complicated by his absinthe consumption.

MS Drugs reduce inflammation, helping reduce relapses and slow disease progression

Disease-Modifying Drugs calm the body's inflammatory response to help stave off relapses—when new or existing MS symptoms show up for a day or longer. Avoiding smoking, exercising, reducing stress via mindfulness, checking for vitamin D deficiencies, drinking more water and eating well, all can slow disease progression. [The jury's still out on if HRT around the time of menopause may reduce dementia risk](https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(25)00122-9/fulltext) Estrogen can reduce inflammation and support neural growth in the brain, and some research has suggested that beginning hormone replacement therapy around menopause—versus later in life—reduces Alzheimer's disease risk. Still, a recent systematic review concluded that taking HRT didn't affect dementia risk, regardless of when women started taking it, so the science remains unsettled.

GLP-1 drugs mimic a natural hormone that triggers appetite-suppressing effects

Ozempic, one of the brand names for the drug semaglutide, was originally developed in 2012, to help treat Type 2 diabetes. Among other effects, the drug mimics a naturally produced hormone known as GLP-1, which is released while eating to let our bodies know we are full.

Using psychedelics to manage a cancer diagnosis

Dr. Roland Griffiths helped lead the revival of psychedelic research, often prescribing the use of psilocybin to address severe depression or anxiety in patients. This podcast explores how Griffiths leaned on his own career after being diagnosed with cancer and facing the prospect of death.

The evolution of dream science—from interpretation to advanced brain imaging

In the mid-1900s, dream scientists would tape study participants' eyes open, wait for them to fall asleep, and attempt to influence their dreams by shaking, tickling, and more. Now, advanced techniques like MRIs have shed new light on what’s happening in the brain as we sleep.

A man with organ failure used AI to speed discovery of his miracle drug

David Fajgenbaum had a few months to live after a diagnosis with a rare form of Castleman's disease. By studying his blood, medical records, and broader literature, he was able to identify the cause of his condition and a treatment. He's been in total relapse for ten years.

See how antidepressants were discovered

The decadeslong journey to the three major types of antidepressants began with medications designed to treat other maladies. Watch to learn more about how attempts to treat tuberculosis and blood pressure disorders led to new insights about neural chemistry and mood.

Two festival-goers were hospitalized after receiving peptide injections, raising questions

Investigative journalism shop ProPublica wrote about two people who became extremely ill following antiaging peptide injections. Authorities were examining whether the individuals were sickened by an infection, contamination related to the injections, or an issue with the medication itself, according to documents obtained by the journalists at ProPublica.

Changes in vision or eye pain can be early MS symptoms

This occurs due to myelin degradation around the optic nerve, impairing its ability to transmit visual information to the brain. Individuals may especially experience eye symptoms after exercising or taking a hot shower because boosted body temperatures slow down nerve function in nerves already damaged by MS.

Pharmaceutical companies can use ChatGPT to improve drug development

Moderna has incorporated the tool into its workflows to accelerate analysis and identify optimal drug dosage from clinical data. The company's legal team also uses a custom GPT—Contract Companion—to break down and summarize contracts quickly.

In a first, eye prosthesis has restored sight to macular generation patients

In a clinical trial, 27 of 32 participants with advanced macular degeneration regained enough vision to read books, food labels, and subway signs about a year after receiving a prosthetic retina device. This is the first device to restore functional vision to patients with incurable vision loss, though in this case they can only see in black and white, with no shades in between.

Longer-duration space missions may amplify astronaut motion sickness

NASA is using the Kraken, a 50-foot-long, 100-ton US Navy research device, to simulate space motion sickness and vertigo and test possible recovery strategies, including testing out different, specific head movements. The Kraken, located at Wright-Patterson Air Force Base near Dayton, Ohio, can rotate participants at exposures of up to 3G.

A BPPV patient describes how a neck massage fueled crippling vertigo

The pressure, she says, dislodged tiny crystals in her inner ear that are crucial to balance. The condition is called benign paroxysmal positional vertigo, or BPPV.

Dr. William Gorgas eradicated yellow fever in Panama, crucial to canal construction

The disease was one of the factors hampering the French effort to build the canal. Gorgas' experience elsewhere in the Caribbean had taught him that good drainage and quaranting patients were essential, and he would eventually apply mosquito prevention tactics on a mass scale.

Over 28% of US adults use yoga for pain management

According to a 2022 study, 28.8% of adults used yoga as a way to manage pain. That's a significant uptick from 2002, when only 11.2% did. The most used approach was chiropractic, which 85.7% used.

Aspirin was the first synthesized anti-inflammatory drug

Once used by the ancient Sumarians—extracted from willow bark—but now synthesized in the lab, the active ingredient of this popular medication has been used to treat headaches and pain for thousands of years.

Why the human brain loves opioids

When opioids enter the brain, they dock in receptors, blocking electrical pulses such as those that communicate pain. They also trigger the release of dopamine, a neurotransmitter tied to motivation and associated with stress relief.

Why are kids increasingly diagnosed with myopia?

According to the World Health Organization, 40% of the world will have myopia—nearsightedness—by 2030. This NPR podcast episode details why people are being diagnosed with myopia at increasingly younger ages. Early onset myopia can lead to...

Mapping where the drug captagon is seized worldwide

In the 1960s, Captagon was patented in Germany as a stimulant similar to amphetamines. It was prescribed for a time to address narcolepsy, ADHD, and other conditions. As its addictiveness and psychosis-inducing quality became more apparent, the drug has been banned in many countries. A robust illicit manufacturing of the drug endures in the Middle East, especially in Syria and Lebanon. Track locations where the drug has been seized on this updated map.

Losing a brain-computer interface can trigger lasting psychological distress

A clinical trial participant with severe epilepsy described becoming “one” with her implant after it gave her unprecedented control over her seizures. When the device was removed due to the company shutting down, she experienced deep emotional trauma and a sense of personal loss.

Diagnosis as an adult can have huge benefits, including helping someone with ASD to feel real

This first-person account of a woman diagnosed with autism at age 31 covers her experience of why it was useful for her to receive her diagnosis as an adult and how it helped her to understand her life and her feelings of 'being an imposter.'

A psychiatrist warns that chasing happiness can lead to misery

Rafa Euba, a retired consultant psychiatrist, argues that happiness is a vague and abstract concept that is hard to quantify. He suggests accepting that suffering and pain are a normal part of life. An attainable goal for one's life is to attempt to minimize pain, and pursue balance and contentment rather than a false ideal of permanent bliss.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

See the evolution of Ebola vaccine and treatment development.

The hormonal disorder PCOS was renamed PMOS in 2026, a move designed to improve care and research by shifting the focus to the hormonal causes of this condition that affects 1 in 8 women.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

After 25 people used virtual reality headsets to practice flying with virtual wings—flapping their arms—their visual cortex responded to the wings almost as if they were real arms, treating them as body parts.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

Double world record holder Hunter Ewen helped conquer his fear of balloons, called globophobia, by training to win Guinness World Record titles for balloon inflation.

In 1939, baseball star Lou Gehrig delivered his inspirational 'Luckiest Man' speech after retiring due to the health condition that now bears his name.

Larger animals like giraffes, elephants, and blue whales have developed a unique defense against cancer, a phenomenon known as Peto's Paradox

One of the most famous portraits ever taken is 'Afghan Girl' (1984) by Steve McCurry, yet the subject Sharbat Gula went much of her life without being identified or benefitting from the image's success.

See images of medical cases of firework injuries shared on this 'Instagram for doctors.' (Warning: Graphic content)

Alzheimer's can lead to brain shrinkage, with an average of around 2% of volume reduction per year

The Dracula character, now seen as the vampire archetype, was inspired by a seafood-induced nightmare its creator experienced.

Astronauts have repaired genetic damage in space using CRISPR—a molecular tool that can make precise changes to DNA and is used in single-celled organisms to attack invasive viruses.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

After her fellow cult members tried to kill her with an LSD-infused hamburger, one member of the Manson Family, the murderous cult led by Charles Manson, decided to testify against the group's leader.

American dance legend Martha Graham, sometimes called 'the Picasso of dance,' refused to perform at the 1936 Olympics in Berlin and conceived the piece 'Chronicle' in response to the experience.

Hotels in Cannes, the glamorous city on the French Riviera, hire hawks to ward off seagulls during the city's famous film festival.

A Yale student wrote a profound essay about the consulting industry's influence on elite college students that was published in a book of her writing after she died in a post-graduation car accident.

Graffiti dates back to at least ancient Pompeii, where citizens scrawled messages to one another on public walls

Dorothy's famous entrance into Oz in 'The Wizard of Oz' relied on analog tricks, including a body double and sepia-toned paint, as much as it did on technology

A century of Billboard issues documenting the evolution of popular music.