Dietary supplements are regulated like foods

The dietary market is worth more than $60B

Listen to this question and answer session with the US Food and Drug Administration about dietary supplements—vitamins, minerals, probiotics and similar products people may buy in liquid, pill, or powder form. They are categorized legally as a category of food and can be legally brought to market without the FDA even knowing about it, though consumers can tell FDA about issues with the products and FDA can take action to remove dangerous or unlawful items after they're available.

The FDA does not approve dietary supplements before they go to market

The US Food and Drug Administration does not regulate products including vitamins, probiotics, and herbal mixes as drugs due to the Dietary Supplement Health and Education Act of 1994, which amended the Federal Food, Drug, and Cosmetic Act. Because dietary supplements are regulated as a subcategory of foods, inspectors do not assess whether dietary supplements work as advertised before sale.

Reporting if supplements make you ill helps FDA know what products to investigate

The US Food and Drug Administration regulates supplements like foods and can only take action about a supplement if they learn that there are problems with it after it's on the market. This website allows consumers, industry, and others to file a complaint about a product that made them ill or raised other concerns.

Supplements often have issues with impurities, toxins, and inaccurate labels

Consumer Reports' tests of more than 20 supplement powders and shakes in 2025 found that more than two-thirds of them contain unsafe levels of lead. Some contained 10 times the amount of lead that's considered acceptable to ingest in a day. The levels they found, in some cases, were even higher than when they tested the products 15 years earlier.

ConsumerLab is a watchdog site reviewing supplements for quality and recalls

The group purchases supplements and tests them for accuracy. When it tested 26 popular B vitamin supplements, it found five failed their tests because they provide either significantly less or much more of the ingredients than listed. This type of product-label mismatch can occur because the FDA does not regulate these products as it would a drug.

Investigation finds 'influencer' dietitians paid to promote sugar, supplements on social media

A joint investigation by The Examiner and The Washington Post found that food, beverage, and supplement corporations and groups have paid registered dietitians on social media to promote content that goes against decades of scientific evidence on...

Search this citation-heavy database of nutrition and supplement research

Explore a reference site that aggregates and summarizes peer-reviewed studies on hundreds of supplements and dietary interventions. It is ad-free and funded by subscriptions, making it a health resource without a financial stake in what you buy.

USP-verified label on supplements means a nonprofit confirmed what's in the bottle

The black-and-yellow USP-verified program seal on a dietary supplement bottle means that the nonprofit US Pharmacopeia tested a sample of the product and verified that it was made in a facility with good manufacturing practices and that it will dissolve in the body. Their certification also means they tested to confirm that the product contains the ingredients listed on the bottle at the specified levels, and that it doesn't contain harmful levels of certain dangerous contaminants.

See preferred supplements across different countries in 2025, by generation

Millennials and Gen Z typically took more supplements than other age groups across vitamins, proteins, minerals, and herbal supplements, according to 2025 data from a Global Consumer Insights Survey conducted in 55 countries. Roughly two-thirds of Gen Z respondents stated they'd taken vitamins in the past 12 months. (Some users may experience a paywall.)

Humans need vitamins, but research is mixed on taking supplements

When an organism needs an organic molecule to survive, but cannot synthesize enough of it itself, that molecule is called a vitamin. Typically, we consume vitamins through food, but many resort to supplements—a common and mostly unregulated practice.

Vitamin D supplement pills are linked to rising cases of vitamin D toxicity in the US

Vitamin D deficiency is common. But taking Vitamin D supplements in doses exceeding 4,000 IU/day (a measurement of vitamin biological activity) for prolonged periods can raise bodily concentrations of this vitamin to dangerous values. US National Poison Data indicates that the annual average of vitamin D poisonings from 2000-05 was 196, but this rose by 1,600% to 4,535 per year for the period of 2005-11.

At the beginning of the 20th century, a group of young men ate standard American food—replete with food additives like borax and formaldehyde—as part of government research to better understand food safety.

Health food broke into the mainstream by the 1980s

A 1984 New York Times story noted that Americans were eating less red meat than a decade prior, and that, in general, the country was “talking, thinking and worrying about what they eat to a degree unique in the nation's history.” The feature then details foods that were then considered bizarre: whole-grain muffins, hummus, and a variety of vegetarian dishes. (Some readers may experience a paywall.)

Listen to how the 1902 'poison squad' experiments changed food safety in America

As part of government research, a group of young men were paid to eat standard American food—replete with food additives like borax and formaldehyde—which revealed the dangers of unregulated food. The work was led by the first FDA commissioner, Harvey Wiley, who helped end the "century of the great stomachache."

US federal law dictates that all ads must not be deceptive

It also dictates that all ads must be “not misleading, and, when appropriate, backed by scientific evidence.” However, enforcing these laws can be difficult given the massive number of ads that run all over America each day. This explainer on the subject from the FTC provides more information.

Telehealth demand for GLP-1s is booming as consumers seek easier access

Telehealth companies are rapidly expanding access to GLP-1s, but some doctors and researchers worry that these services are inadequately screening patients, skipping follow-up care, and prescribing cheaper compounded versions with little regulatory oversight—setting the stage for troubling medication errors and serious adverse events.

Ultra-processed foods are made to maximize cravings and encourage overeating

Often disguised as healthy options like granola bars and low-fat yogurt, these foods silently fuel chronic diseases, despite dominating diets. Reviewing labels for ingredients like stabilizers and emulsifiers can serve as indicators to help identify these products.

Collagen supplements have become a multibillion-dollar industry

Beginning in our 20s, the amount of this protein in our skin, muscles, and connective tissue declines. But independent, high-quality studies—like those that are double-blind—have not yet shown a significant association between their use and evidence of it improving skin elasticity, reducing wrinkles, or combating hair loss. Some collagen supplements do seem to help with joint pain and knee function, but NPR cautions that studies on that purpose are industry-funded.

Scientists from the frontline discuss the future of antibiotics and superbugs

Superbugs are a very real problem, but researchers around the world are working to advance our understanding of these pathogens and develop new medicines. This podcast talks with several scientists on the frontier of superbug research, offering insight into what we know—and what the future of medicine may look like.

See how DOJ prosecutors took down a pharmaceutical company's executives over the opioid crisis

This FRONTLINE documentary follows federal prosecutors as they used anti-racketeering laws to convict executives at Insys Therapeutics, a pharmaceutical company that bribed doctors to overprescribe a fentanyl painkiller.

How Big Oil misled the public into believing plastic would be recycled

An NPR and PBS Frontline investigation reveals how the oil and gas industry used the promise of recycling to sell more plastic, even when they knew it would never work on a large scale.

Telehealth demand for GLP-1s for weight loss is booming as consumers seek easier access.

GMOs sound scary, but you eat them every day

Why are GMOs bad? They aren’t. We’ve been eating them for decades with no ill effects, which makes sense, because a genetically modified organism is simply an organism, like every other organism, produces hundreds of thousands of proteins, but one or two of them are proteins that were chosen specifically by humans. Watch this 11-minute video for more.

Listen to an in-depth conversation on the links between Parkinson's disease and herbicide exposure and the challenging pace of scientific investigation.

Sesame seed regulations have led to fewer sesame-free products

Food producers have been required to include specific labeling on their packages for sesame since new regulations went into effect in January 2023. In response, some food producers have decided to add small amounts of sesame to foods, including breads, rather than do the costly work of scrubbing their facilities of all possible sesame contamination.

The Office of Chemical Safety and Pollution Prevention regulates toxic substances

This office evaluates and manages risks from industrial chemicals and pesticides. It reviews new chemicals before they enter the market, restricts hazardous substances, and promotes safer alternatives to protect human health and the environment.

Watch these Canadian doctors critique medical accuracy on television shows

Drs. Paul Zalzal and Brad Weening are orthopedic surgeons and members of the Royal College of Physicians and Surgeons of Canada. In this episode, they discuss which television shows they think are the most medically accurate. "Grey's Anatomy" did not fare well in their review.

'Why'd I take speed for twenty years?': an exploration of stimulant ADHD medication

Many people with ADHD are prescribed stimulant medication to assist with symptoms ranging from time blindness to executive dysfunction. This hour-long podcast episode by Search Engine explores the host's experience with ADHD medication and the history of amphetamine and methylphenidate use in the US.

An investigation suggests a Scottish island became awash in forever chemicals via seafoam and seaspray—raising questions about what that means for the safety of other coastal areas.

Read a deep dive on the 'all-purpose healing' peptide BPC-157.

Studies suggest when you sleep is as important as how much you get, and syncing with your circadian rhythms may lead to less fatigue and improved long-term health outcomes

'Shogun,' a 1980s TV series, helped popularize sushi in the US by stimulating an American interest in Japanese culture.

Netflix profits when you're not watching, and its movies are designed that way—read a detail-rich critical essay exposing lesser-known Netflix takes

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

Learn how to read a prospectus, the juicy document that any company must file with the SEC before going public.

See how Ebola tore through Guinea, Sierra Leone, and Liberia in 2014-2016.

Despite being favored by 87% of Americans, Congress does not have term limits.

Human-to-human transmission of hantavirus remains extremely rare, so the 2026 hantavirus cruise ship outbreak doesn't mean we're facing a COVID-style pandemic risk.

Doctors differentiate between a phobia and fear by asking patients whether their fear interferes with their day-to-day activities.

20,000 letters to the advice columnist 'Dear Abby' provide insight into prevailing sex, religion, and LGBTQ fears, anxieties, and concerns from the 1950s onward.

Watch how deep-sea mining equipment collects and processes polymetallic nodules—metal-rich, potato-shaped rocks—from the ocean floor and creates environmentally damaging plumes of sediments.

Calculate how much of your tax dollars go to each federal program based on your income, filing status, and number of children

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

Up to a million Girl Scouts sell about 200 million cookie boxes every spring, generating $800 million, largely because refusing a child is frowned upon

The US dollar is the most widely circulated currency in the world, and is involved in nearly 90% of global transactions

See this overview of the firework rules across all 50 states, ranging from a complete ban on non-professional fireworks in Massachusetts to states with more lax rules like Indiana.

Sunflowers have long been a symbol of nuclear disarmament because they can extract large amounts of radioactive cesium from soil.

The most expensive ad of all time was for Chanel No. 5 perfume and cost roughly $33M to produce in 2004—about $57M in today's dollars.

See how Budweiser's famous Clydesdales spend their days at Warm Springs Ranch, where roughly 70 to 80 of the beer brand's giant horses can be found at any given time.

Prince's sexually explicit 1984 track 'Darling Nikki' attracted the ire of the Parents Music Resource Center, an advocacy group that inspired the Parental Advisory sticker, even though the song ends with a Christian message.