What if we killed every mosquito on Earth?

Mosquitoes are the world's deadliest animal—gene drives could kill them

Historically, killing all disease-carrying mosquitoes has not seemed practical and there are concerns about disrupting food webs. Gene editing to render female mosquitoes infertile creates the theoretical possibility of wiping out disease-carrying species, but concerns remain about effectively limiting this engineered trait to target species.

Mosquitoes top the ranking of the world's deadliest animals

Mosquitos kill about 760,000 people every year. The vast majority of those deaths are caused by malaria, which is transmitted and spread by the Anopheles mosquito. The second-place deadliest animal title goes to snakes, with an estimated human death toll of around 100,000 annually.

Wolbachia: the bacteria that could eliminate dengue fever

Dengue fever, transmitted by mosquitoes, kills more people annually than all types of natural disasters combined. However, mosquitoes that host Wolbachia bacterium have their ability to transmit the virus naturally suppressed, offering a route to eliminating nearly 25,000 deaths annually.

Some mosquitoes are key pollinators—and eat disease-carrying mosquitoes

​​There are more than 3,500 species of mosquitoes, and only a small fraction of them bite humans. They also play vital roles in the ecosystem: One young elephant mosquito, for example, can eat dozens of smaller mosquitoes that bite humans in just one day. Sometimes mosquito-gobbling species are released by humans to control other mosquitoes.

Mosquitoes drink a maximum of 0.01 milliliters of blood in a single meal

That's roughly equal to a human drinking the contents of an entire bathtub. Females, which are the only ones that drink blood, have a sensory nerve that signals when they're getting full, but if it's disabled, a mosquito would keep drinking until it bursts—a scientist conducted that experiment.

Iceland, the last mosquito-free country, detected them in 2025

Recently several of the mosquito species Culiseta annulata were documented in Iceland—the last country that had not yet seen them, underscoring that climate change is shifting the bugs' patterns. Mosquitoes can hide out in human structures to survive icy temperatures. The bugs are now known to live everywhere except the continent of Antarctica.

Billions of flies are being dropped from the sky

The US is dropping billions of sterile flies to stop a deadly parasite. Screwworm maggots eat animals alive, so scientists are collapsing the population by ensuring females can’t reproduce.

Mosquito-borne illnesses have killed captive orcas at SeaWorld

After two SeaWorld orcas died from viruses carried by mosquitoes, scientists warn that mosquito-borne illnesses may be a bigger threat to these captive animals than previously known. Captive orcas spend a lot of time stationary, close to the surface, unlike their wild counterparts. Researchers saw mosquitoes landing on the animals' backs, heads, and dorsal fins, supping on their blood.

From 1970 to 2017, invasive species have caused $1.28T in damage globally

The costliest species were the Asian tiger and yellow fever mosquitoes ($149B), which arrived in the US from Asia and sub-Saharan Africa, respectively. The bulk of their damage came from their transmission of diseases such as Zika, chikungunya, and dengue. (Some readers may experience a paywall.)

Variola: the second-deadliest virus on Earth

Because it was declared eradicated in 1980, many forget smallpox is one of history's deadliest diseases—in its final century, it's estimated to have claimed 500 million lives. This 11-minute video from production studio Kurzgesagt takes a look at...

How Disney World keeps out mosquitos

Disney World may have been built on a swamp, but it's nearly free from the annoyance of mosquitos. That hasn't been an easy task; Disney has worked with engineers and pest specialists on minimizing the invasive bugs through a variety of different methods. This Reader's Digest article breaks down how they've successfully kept the park free from these unwanted guests.

More than 39 million people are expected to die from antimicrobial resistance by 2050

In 2024, researchers published an incredibly detailed study aimed at predicting the real-world impact of antimicrobial resistance over the next 25 years. The key findings were clear: the superbug crisis is poised to get much worse and needs to be addressed. This article offers a clear, concise overview of the study, which was published in The Lancet.

Why Earth would become a more deadly environment without the ozone layer

The ozone layer blocks almost all of the sun's harmful, including dangerous UVC rays that can damage cells by breaking chemical bonds. Without it, rates of skin cancer, crop failures, oceanic die-offs, and widespread ecosystem collapse would increase significantly, making Earth largely uninhabitable.

See how distant aliens could preemptively strike humanity

Could aliens destroy us from light-years away? The team at Kurzgesagt imagines the impact of a highly sophisticated alien civilization setting out to crush humanity and considers the real-world logistics for warfare conducted across the Universe.

Scientists still don't know why DEET is such an effective bug repellent

This chemical, used to keep ticks, fleas, mosquitoes, and other nuisance bugs away, is used by an estimated one-third of the US population and has been available to consumers since 1957. Researchers theorize that multiple mechanisms may be at work to deter bugs, including perhaps masking or confusing bugs' olfactory receptors.

Lightning may kill as many as 320 million trees each year

Ignoring the effects of tree loss resulting from lightning-induced wildfires, researchers at the Technical University of Munich developed a quantitative model to estimate the loss of these organisms due to cloud-to-ground strikes, based on global lightning data and forest structure. They expect the estimate to rise due to increased strikes resulting from climate change.

What is a sneeze? (And can it kill you?)

A sneeze is an important involuntary reflex to expel something that is irritating your nose. But can it kill you? No, say these silly video hosts. Although, the sneeze can expel air, saliva, and mucus at nearly 100 miles per hour in a five-foot radius. See them break it down with this quick, quirky video.

Feral and free-ranging cats rank among the most harmful invasive species

Transported across the planet by humans, cats can now be found in many environments and are estimated to kill about 2 billion birds each year in the US. Studies suggest cats have contributed to the extinction of at least 63 species worldwide.

See the geographic spread and incidence of malaria

This graphic shows the estimated global burden of malaria in 2025 as new cases per 1000 people at risk.

One-third of the world’s food supply relies on pollinators

By supporting crop production and farmland ecosystems, these animals contribute over $200B to the global economy. A 3% to 5% decrease in this production may result in as many as 427,000 deaths due to nutritional deficiencies.

Why scientists are making robot insects

Insects have much to teach us about flying, jumping, moving quickly, and more. So, roboticists are studying how insects do the ridiculous things they do, like walk on water or jump fifty times their body height, to inform their design and engineering of a new slate of robots: tiny ones. Learn the future of this type of robot with this fascinating video with insights into both insects and robots.

View a breakdown of the identified species on Earth

Over 2 million species have been documented by scientists, but there may be as many as a billion distinct species. The vast majority of the species on Earth are insects, while mammals form the smallest group.

Nearly 5,500 crows died during four months in 1999 from West Nile in NYC

Subsequent testing made clear the disease at that point was 100% fatal to crows. From 1999 to 2004, millions of birds died as West Nile spread across North America, but the virus fortunately became less virulent as it moved westward.

If the Earth stopped spinning, 85% of the world's population would experience supersonic winds

The planet's equator moves about 470 meters per second—over 1,000 miles per hour—and air there would continue moving at this speed for several minutes if the ground stopped rotating. These conditions would cause tsunamis, global storms, and fling debris fast enough to destroy nearly all human-made structures.

Why death is caused by a dearth of ATP

Though people die from many causes, this video makes the case that a lack of adenosine triphosphate production in the body is what kills almost all of us. Without ATP, physiological processes grind to a halt, and organs stop functioning.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

Visualize how CRISPR-Cas9—a type of immune system used by single-celled organisms to attack invasive viruses—targets and makes precise changes to a gene's DNA.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

Discover the catastrophic consequences of a failure of the US electrical grid—something that is more likely than many Americans think.

11 people died from firework injuries in the US in 2024.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

Hookworm infection, though risky, may help fight certain autoimmune conditions by tamping down the immune system's inflammatory response.

Indefinite cloning of some endangered species may not sustain their longevity because cloning success rates decrease as genetic mutations accumulate.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

The use of fungi to detoxify land and water—a process known as mycoremediation—has been used to clean up natural resources affected by the 2025 California wildfires.

Apeirophobia is an overwhelming fear of living forever, perhaps stemming from the brain's inability to conceptualize an infinite life.

Scientists testing how climate change affects plants found, in a years-long simulation study, that poison ivy grew 70% faster with the resulting extra carbon dioxide.

In 2018, 26-year-old missionary John Allen Chau was killed by tribesmen after attempting to reach and evangelize on India's isolated North Sentinel Island

After NASA's Voyager 1 captured Earth as a single pixel as it left the solar system in 1990, astronomer Carl Sagan used the image to reflect on humanity's fragility and the responsibility to protect 'the only world we've ever known.'

Chaos theory—informally known as the butterfly effect—is the reason why weather forecasts are presented with probabilities rather than certainties.

In 2019, a laptop loaded with six of the worst malware in history and described as 'an exhibit of historical weaponry' sold for $1.3M.

US intelligence allegedly pursued more than 600 schemes to assassinate Cuban revolutionary Fidel Castro.

While atoms are normally made of protons, neutrons, and electrons, exotic ones have been built with antimatter—alternate versions of normal matter that live for fractions of a second and are about a billion times as rare.

All rainbows are 'raincircles' caused by water droplets separating white sunlight into a spectrum of colors, but Earth's surface blocks the bottom half of the circle from our line of sight.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

Bone marrow (soft tissue found inside certain bones) generates roughly 500 billion new blood cells each day

The boiling temperature of water decreases with increasing elevation because the molecules need less energy to overcome the lower atmospheric pressure associated with thinner air.

Double world record holder Hunter Ewen helped conquer his fear of balloons, called globophobia, by training to win Guinness World Record titles for balloon inflation.

The Russia-Ukraine conflict is the largest ground war in Europe since World War II in casualties, forces mobilized, and displacement of civilians.

For centuries, Niagara Falls has been a magnet for daredevils seeking to conquer one of nature's most powerful wonders, with its 200-foot drop and water rushing at 32 feet per second with 280 tons of force.