Ebola species have historically been named after the places where they were discovered, stigmatizing residents of those areas, including Bundibugyo, in Uganda

Three Ebola species are responsible for most large outbreaks of the disease

The Ebola Zaire, Sudan, and Bundibugyo species are the three ebolaviruses responsible for most large outbreaks in Africa. Among these, Ebola Zaire is the deadliest, with as many as 90% of cases resulting in death. Ebola Sudan has about a 50% fatality rate and has caused several outbreaks in Uganda. More recently discovered in 2007, Bundibugyo causes death in about 30% of people and has caused two large outbreaks in Uganda and the Democratic Republic of the Congo (DRC) before the spring 2026 DRC outbreak. Taï Forest virus is the rarest and is known to have infected a single person in the Côte d'Ivoire in 1994.

Three Ebola species are responsible for most large outbreaks of the disease, yet the only approved Ebola vaccine is known to work against just one of them.

The 2026 Ebola outbreak in the DRC is spurring new Ebola vaccine development for the Bundibugyo species.

West Nile is named after the district in Uganda where it was first isolated from a patient

In 1937, scientists isolated the virus from a woman in the West Nile District of Uganda. It's since been detected in much of Africa, Eastern Europe, West Asia, the Middle East, and was first detected in US patients during an outbreak in 1999.

The 2026 Ebola outbreak is hampered by a lack of vaccine against the species of the virus, heightening the need for rapid tests to aid in disease control

Clinics in the Democratic Republic of Congo saw patients with Ebola symptoms months before the disease was identified. The identification lag was due to inadequate diagnostics that could not accurately or quickly identify the virus's myriad species. Contact tracing and better diagnostics will be required to tamp down the outbreak.

Scientists have struggled to pin down Ebola's natural reservoir species for decades, but the available evidence suggests that it's very likely fruit and insect-eating bats found in Africa.

The 2026 Ebola outbreak in the DRC is spurring new Ebola vaccine development for the Bundibugyo species

An experimental vaccine candidate from Moderna will use the company's mRNA vaccine platform—the same one which enabled the COVID-19 vaccine to be rapidly developed during the pandemic.

Ebola's natural reservoir species are likely bats

But the virus doesn't seem to sicken the animals, so capturing an infected bat and performing necessary tests has remained challenging. Though many scientists believe fruit bats are the reservoir species for the virus, Ebola viral RNA fragments were detected in a greater long-fingered bat captured in 2016 in Liberia. The species isn't a fruit bat—it roosts in caves and feeds on insects. The scientist behind the discovery states that he believes the virus likely infects multiple host species and that the hosts may differ regionally. (Some users may encounter a paywall.)

See the evolution of Ebola vaccine and treatment development.

Marburg virus, related to Ebola, is also extremely deadly

Discovered nine years before Ebola, Marburg is part of the same filovirus family. While this virus is less contagious, it can still be deadly. Currently, no vaccines exist against this disease. (Some users may encounter a paywall.)

Ebola is a filovirus, meaning it resembles a thread under a microscope

Filovirus is derived from the Latin word 'filum', meaning 'thread.' That term describes its thin, flexible, threadlike appearance. Originally isolated in 1976, the microscopic image of the Ebola virus is now famous, even portrayed in the movie Outbreak. In fact, Ebola's threadlike appearance can vary in both length and degree of twisting, sometimes resembling a bowl of spaghetti.

Ebola is a filovirus, meaning it resembles a thread under a microscope, though it sometimes twists and can resemble a bowl of spaghetti.

Marburg virus, related to Ebola, is also extremely deadly, and has no available vaccine.

See how Ebola tore through Guinea, Sierra Leone, and Liberia in 2014-2016.

How the most famous Ebola outbreak book got aspects of the disease so wrong

Richard Preston's 1994 book The Hot Zone brought knowledge of Ebola to the masses. But, beyond the poor portrayals of the science and the scientists, the book fostered fearmongering about Ebola, with portrayals of "liquefying," "dissolving," and "bleeding out." These falsehoods about Ebola have persisted for decades and appear to be reinvigorated with every new emergence of the disease.

HIV originated in Central and West Africa from a virus in chimpanzees

Researchers believe the virus crossed from chimpanzees to humans through bushmeat practices in the early 20th century, with genetic studies suggesting the most recent common ancestor of the HIV-1 M group, which is responsible for the global AIDS pandemic, emerged around 1910–1930 in Léopoldville (now Kinshasa) in the Belgian Congo.

Watch how viruses like Ebola can spill over from animals to humans—and vice-versa.

How the most famous Ebola book, The Hot Zone, which sold 3.5 million copies and was translated into 30 languages, got aspects of the disease so wrong.

Every virus is classified into 7 groups based on genetic differences

Viruses infecting humans have been named based on symptoms ("chickenpox") or the location or animal in which they were first discovered ("Bolivian Haemorrhagic Fever" and "Monkeypox"). For clarity among scientists and to reduce stigma, virologists classify the 15,000 known viruses (270 of which infect humans) by their basic genetic material.

Cultural norms about how to handle the bodies of loved ones have hampered Ebola responses in West Africa

Awareness of local burial and grieving traditions eventually helped healthcare workers fight the spread of the virus. As healthcare workers and burial teams altered their procedures during the 2014 West African Ebola outbreak, and as community leaders pressed people to adapt traditional ceremonies, the spread of Ebola began to slow.

Explore what it's like inside a patient isolation unit, used in situations such as treating a patient or suspected patient with Ebola.

See how the Ebola virus affects blood circulation in the human body

Ebola infects and disables immune cells, causing a cascade of events that result in small blood clots throughout the body, weakening blood vessels, and interrupting blood flow to key organs.

Explore what it's like Inside a patient isolation unit

Containing a contagious disease like Ebola requires strict protective measures. There are several specialized medical wards to contain deadly infectious diseases at hospitals across the U.S. Emory University has one such unit, where 4 patients were treated during the 2014 outbreak.

Cultural norms about how to handle the bodies of loved ones in communities in West Africa have hampered Ebola responses.

Ebola infects and disables immune cells, triggering a cascade of events that leads to small blood clots throughout the body, weakening blood vessels and interrupting blood flow to key organs.

Explore inside a mosquito factory where millions of mosquitoes are bred weekly

In Medellin, Colombia, scientists are infecting Aedes aegypti mosquitoes with Wolbachia, a bacterium that wouldn't otherwise infect the species, but does block its ability to transmit dengue, Zika, yellow fever, and chikungunya. In the wild, infected mosquitoes would breed with wild mosquitoes, pass down Wolbachia, and thus reduce disease transmission.

'Sloth fever' is an emerging health threat, especially to pregnant women

This disease, caused by the Oropouche virus, is found in animals including sloths, primates, and birds. It primarily spreads through the bite of midges—insects commonly called "no-see-ums." It's endemic to the Amazon region, but US travelers are increasingly contracting it internationally.

Volcanoes in the 1340s likely helped trigger the Black Death

The "bubonic plague" that wiped out roughly half of Europe and Asia originated from many factors. Recent research suggests volcanic eruptions contributed as well. The "aerosol" effects of matter released from eruptions likely prompted famine and accelerated the spread of infected fleas riding on grains avoiding spoilage.

Watch David Attenborough's unexpected interaction with a family of gorillas on 'Life on Earth'

On the border between Rwanda and the modern-day Democratic Republic of the Congo, Attenborough used specific vocalizations and behaviors to approach a female gorilla peacefully, only to have two of her children lie down on him. Through a comical exchange, the incident helps show the creatures to be the opposite of the aggressive, violent stereotypes about them.

Archaeologists race to record ancient Nubia

Long ignored by white archaeologists as a mere footnote, modern scientists are now racing to document what’s left of the African civilization. Evidence of ancient Nubia is at risk of vanishing under environmental, societal, and political pressures. This Undark Magazine article walks you through archaeologists' fight to record ancient Nubia.

The cholera bacteria was first isolated in 1854—but the discovery was largely ignored

The pathogen was isolated by the Italian physician Filippo Pacini in Florence, Italy, though his discovery was largely ignored in favor of the popular miasma—bad air—theory of disease at the time. The pathogen was separately isolated about three decades later by German microbiologist Robert Koch.

Most invasive species are spread accidentally by human activity

In the Florida Everglades, Burmese pythons were only found as pets in the 1980s, but their escapes and releases since then have led to a population of hundreds of thousands as of 2024. The spotted lanternfly—native to Asia—was first detected in Pennsylvania in 2014 and has since spread to about 20 states by hitchhiking.

How quidditch brought a Ugandan school to life

The world phenomenon of Harry Potter inspired millions of kids to read. The books, and the make-believe game quidditch (played by the hero), have inspired a real-life sport called Quadball, based on the fictional game involving flying broomsticks. Teacher John Ssentamu brought the game to his town of Katwadde in Uganda to bring kids—long absent from school—back to receive an education. A documentary crew filmed them playing in an inspiring story of education and community.

The Chinese market for donkey hides has created a new source of diseases

Since 1992, China’s donkey population has dropped more than 80 percent. This report examines how China’s booming demand for a traditional medicine known as e-jiao, made from collagen from donkey hides, is leading to the slaughter of 6 million African donkeys annually, and providing a new source for zoonotic diseases.

The Chernobyl exclusion zone has become a unique wildlife refuge

Within the area—roughly the size of Yosemite National Park—animals such as wolves, bears, and feral dogs descended from the pets left behind have gradually adapted to low-level radiation. Eastern tree frogs in the area have darker skin than usual, which may have helped protect them from ionizing radiation.

This real-time tracking of the hantavirus cruise ship outbreak in May 2026 offers a unique glimpse into the global reach of the outbreak and whether the virus sickened passengers and their communities around the world.

A podcast detailing the drug markets of East and Southern Africa

The African continent plays a critical role in the global illicit drug market. Often forgotten when discussing drug trafficking, organized criminal networks in Africa have established relationships with other criminal organizations around the world....

The okapi was once considered a cryptid, or an animal with an unverified existence

Similar to dragons or Bigfoot, the okapi was once believed to be a mythical animal, known colloquially as an "African unicorn." Its confusing features include zebra-like legs on a donkey-esque body with a giraffe-like head. However, this animal is both real and quite cute.

Some Pokémon have been named after real and fictional organisms, while some real-world species have been named after Pokémon, such as Chilicola charizard and Binburrum zapdos.

Volcanic activity may have triggered the Black Death by spewing gases that led to crop failures in Europe, thus forcing the import of grain ships with plague-infested fleas.

The American cockroach is actually from Africa, an apparent hitchhiker aboard ships carrying enslaved people, with evidence suggesting the bug may have arrived in the New World as early as the 1600s.

Urushiol, the oily toxin in poison ivy, can remain allergenic on clothing for years.

NBA superstar Victor Wembanyama spent the 2025 summer training with monks in central China to enhance his body and mind.

The US first hosted the World Cup in 1994, a tournament that lives in soccer infamy for its poor planning and the murder of Colombian player Andres Escobar, who'd accidentally scored on his own net.

Louisiana's 'Cancer Alley' is infamous for having some of the highest industrial pollution, toxic air emissions, and cancer risks in the US.

Budweiser stores yeast derived from the original 1800s strain in a secret bunker, which only the Head of Yeast Management can access—not even the CEO

The Great Salt Lake's distinct dual coloration results from high-salinity organisms that only live in the northern portion and produce a purple protein.

One of the most famous portraits ever taken is 'Afghan Girl' (1984) by Steve McCurry, yet the subject Sharbat Gula went much of her life without being identified or benefitting from the image's success.

Some coin denominations have ridges etched on their sides, partly to prevent counterfeiting, in a practice called 'reeding.'

The United States is one of only around two dozen countries with a fully federal system of government, in which power is divided between national and state governments.